{"title":"Anatomy across centuries: From ancient Greeks to modern innovations. The merit and significance of autopsies today","authors":"Iryna Tehlivets","doi":"10.24969/hvt.2023.425","DOIUrl":"https://doi.org/10.24969/hvt.2023.425","url":null,"abstract":"The article discusses the history of anatomy in the context of its development from antiquity to modern achievements, including the latest visualization technologies. The influence of historical anatomical research on the understanding of the structure and functions of the human body is analyzed. The article discusses the problems that arise from the attractiveness of the latest imaging technologies and emphasizes the enduring value of practical autopsy experience. We should not forget that the essence of medical practice goes beyond digital simulations - it is rooted in the tactile exploration of human tissues and organs. In a world characterized by rapid technological progress, it is extremely important not to forget about the invaluable knowledge gained through centuries-old autopsy traditions. The complex dance between tradition and innovation has shaped the trajectory of our understanding of anatomy, pathology, and medical intervention. From the ancient Greeks who laid the foundations for anatomical research to the advanced technologies of today that offer us unprecedented insights into the human body, the path of medical discovery thrives on a delicate balance between respecting the past and embracing the future. The field of cardiovascular medicine is a vivid illustration of the symbiotic relationship between tradition and innovation. Autopsies, with their timeless significance, constantly guide doctors and researchers to improve interventions and surgical techniques. The intricate details revealed during autopsies have paved the way for remarkable achievements, from elucidating the pathogenesis of diseases to improving surgical procedures.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135482095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the possibility of using spectral analysis of a single-channel ECG for the diagnosis of diastolic dysfunction of the left ventricle of the heart","authors":"Ishenbay Moldotashev, Yuriy Bogdanov, A. Sorokin","doi":"10.24969/hvt.2023.424","DOIUrl":"https://doi.org/10.24969/hvt.2023.424","url":null,"abstract":"Objective: Assessment of diastolic function of the left ventricle (LVDF) makes it possible to detect chronic heart failure (CHF) at the preclinical stage of development, when its progression can still be prevented. Doppler echocardiography (echo) is the most accurate non-invasive diagnostic method for left ventricular diastolic dysfunction (LVDD), requiring expensive equipment and trained professionals. The development of an accessible screening method for the diagnosis of LVDD is an urgent and practically significant task. Purpose of the study was to evaluate the diagnostic value, sensitivity and specificity, positive predictive value and negative predictive value of the method of spectral analysis of a single-channel electrocardiogram (S-ch ECG) proposed by us for the diagnosis of LVDD in comparison with Doppler echo as a reference. Methods: The study involved 60 people (35 patients on program hemodialysis with arterial hypertension and 25 healthy individuals). Among the patients there were 19 men and 16 women aged 29 to 65 (45.9 (12.8)) years. Among the healthy were 15 men and 10 women aged 25 to 63 (43.2(11.8)). Doppler echo was performed on the SonoSite Micro Maxx Belse X2 apparatus. LVDF was determined according to the generally accepted method. S-ch ECG was taken with portable recorder DuoEK 118 from Lepu Medical. LVDD was determined by S-ch ECG spectral analysis as the ratio of the sum of harmonic power in the period of early diastolic filling to the sum of harmonic power during the period of atrial contraction. Results: The sensitivity of the method developed by us was 0.74, and the specificity was 0.84. Positive predictive value was 0.87 and negative predictive value was 0.70. Chi-square: 15.043, p<0.0001 - the presence of a relationship is statistically highly significant; Phi=0.514, p<0.0001 - the presence of a connection is highly significant. Area Under the Curve is 0.791 (0.061) with a confidence interval of 0.672 to 0.911. The obtained values indicate that S-ch ECG scores are fairly good predictors of LVDD. Conclusion: Spectral analysis of S-ch ECG has a high sensitivity and sufficient specificity for the diagnosis of LVDD. This method can be used for remote mass screening studies for the purpose of preclinical diagnosis of CHF.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134975812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of mountain climate on multiple sclerosis","authors":"Begimai Kadyrova, Asel Jusupova, Nurzhan Dzhaparalieva, Bolot Kulov","doi":"10.24969/hvt.2023.423","DOIUrl":"https://doi.org/10.24969/hvt.2023.423","url":null,"abstract":"Objective: Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. Although the exact cause of multiple sclerosis is unknown, it is believed to be a combination of genetic and environmental factors. One of the environmental factors is climate, including the influence of the mountain climate on this disease. We aimed to analyze current evidence on influence of mountain climate on multiple sclerosis. Methods: We followed the guidelines for the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement. Reviewers systematically searched Scopus, PubMed and EMBASE for peer-reviewed publications in English from January 1994 to December 2022 reporting MS and influence of mountain climate. The outcome was change in MS incidence rate according to geographical region. Results: The mountainous climate is characterized by high-altitude, low humidity and extreme temperatures, which can have both positive and negative effects on multiple sclerosis. On the one hand, a cold and dry mountain climate can be beneficial for people with multiple sclerosis, as it can reduce inflammation and improve symptoms such as fatigue, cognitive impairment, and spasticity. In addition, high altitude may have a protective effect on multiple sclerosis, as it is associated with a lower incidence rate. On the other hand, mountain climates can also have a negative impact on multiple sclerosis, especially in terms of vitamin D deficiency. Sun exposure is the main source of vitamin D, and people living at higher altitudes get less sunlight due to the thinner atmosphere, resulting in the body producing less vitamin D. Conclusion: Thus, the influence of mountain climate on multiple sclerosis is complex and depends on many factors. Further research is needed to better understand the relationship between altitude and MS risk.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135344236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The angiographic and clinical profile of patients with Takayasu aortoarteritis","authors":"Jitendra Sharma, Tarun Madan, Dinesh Joshi, Riyaz Charaniya, Pratik Raval, Vishal Sharma, Krutika Patel, Himani Upadhyaya","doi":"10.24969/hvt.2023.422","DOIUrl":"https://doi.org/10.24969/hvt.2023.422","url":null,"abstract":"Objective: Takayasu arteritis is a rare, chronic, inflammatory disease that primarily affects the aorta and its major branches. It mainly affects young females, and it can cause significant morbidity and mortality if untreated. The aim of this study was to evaluate the demographic profile, clinical manifestations, diagnostic features, angiographic findings in patients with aortoarteritis (Takayasu arteritis). Methods: We enrolled prospectively 116 patients with Takayasu arteritis who came to Cardiology OPD at tertiary cardiac care hospital. We looked for constitutional symptoms, heart-related symptoms, systemic hypertension, neurological symptoms and upper & lower limb fatigue and claudication. We evaluated our patients using different diagnostic criteria: clinical, ACR criteria and Indian Takayasu Activity score. We also studied the angiographic profile and lesion characteristics in these patients, based on peripheral and coronary angiograms. Results: We studied patients consisted of 14 male patients (12.1%) and 102 female patients (87.9%). Type V Takayasu arteritis was most common type (36.2%). Fatigue (60%) was most common cardinal symptom followed by myalgia (30%) and arthralgia (10%). About 43% of patients had neurological symptoms. Systemic hypertension (67%) was the most common manifestation of renal involvement. 110(95%) of the patients met clinical criteria and 105(91%) patients had American College of Rheumatology (ACR) score ≥3. Angiographic evidence of left renal artery stenosis was more (20%) than right renal artery stenosis (15%). bilateral renal artery involvement was found in 29% of patients. Conclusion: Type V Takayasu arteritis was most common type (36.2%) of total study population. Hypertension and subclavian artery involvement both were seen in 2/3rd of population. Angiographic evidence of right and left renal artery stenosis was seen in 15% and 20% respectively, while bilateral renal artery involvement was found in 29% of patients. Take home message: Takayasu arteritis rarely involves the coronary arteries. Angiographic evidence of right and left renal artery stenosis was observed in 15% and 20% of patients, respectively, with bilateral renal artery involvement found in 29% of patients.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136014854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Superiority of 3D transesophageal echocardiography in assessment of mechanical prosthetic valve dysfunction as compared to 2D transesophageal echocardiography","authors":"Nilesh Chandak, Hasit Joshi, Pooja Vyas, Kamal Sharma, Gajendra Dubey, Iva Patel, Kewal Kanabar","doi":"10.24969/hvt.2023.421","DOIUrl":"https://doi.org/10.24969/hvt.2023.421","url":null,"abstract":".","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134912659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complications of endoscopic ligation of varicose veins in patients with portal hypertension","authors":"Bahrom Bebezov, Talgat Abdykadyrov","doi":"10.24969/hvt.2023.420","DOIUrl":"https://doi.org/10.24969/hvt.2023.420","url":null,"abstract":"Objective: The aim of the investigation is to analyze the results of endoscopic varicose vein ligation (EVL) in patients with portal hypertension; to estimate the character and frequency of early and late postoperative complications after EVL; to evaluate the possibility of endoscopic ligation at the moment of active bleeding. Methods: This work includes an analysis of 138 procedures for endoscopic ligation of the esophageal varices in 111 patients from 2016 to 2020. Intrahepatic form of portal hypertension was in 90 patients, extrahepatic form - in 21 patients. The total number of interventions performed was divided into 2 groups. In the first group of patients with EVL was performed urgently, and the second group includes patients, if necessary, with targeted prescription and secondary prevention of portal esophageal bleeding. Results : In 74 (53.6%) cases out of 138, different types of complications were detected. There were 2 lethal cases (1.4%). It should be noted that there were no lethal outcomes in second group after EVL, and after urgent operations, the mortality rate was 33.3%. The most critical complication of ligation was the resumption of hemorrhage due to the site of ligation in the early (1-3 days) and late periods after surgery (5-10 days). Conclusion: In this analysis of the studied cases of complications after EVL, the most common complication was pain syndrome and early and late bleeding were also identified. We showed that control esophagogastroscopies helped to identify bleeding recurrences; examination algorithms in case of detection of bleeding complication after EVL, and measures to prevent the development of recurrent hemorrhage were also necessary.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136071351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Kochkorova, M. Esenamanova, R. Atambaeva, Tatyana Tsivinskaya
{"title":"Nutrition in coronavirus infection (COVID -19)","authors":"F. Kochkorova, M. Esenamanova, R. Atambaeva, Tatyana Tsivinskaya","doi":"10.24969/hvt.2023.419","DOIUrl":"https://doi.org/10.24969/hvt.2023.419","url":null,"abstract":"Insufficient, irrational nutrition is the most widely spread reason of immunodeficiency. Few is known on nutrition in COVID-19 that caused pandemics worldwide. In this review, we summarized key points of nutrition in COVID patients, including macronutrients and micronutrients.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76162304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dario Mafricaa, Luigi Spadafora, Kristian Galanti, Giuseppe Biondi-Zoccai, M. Bernardi
{"title":"The role of coronary physiology in the management of percutaneous coronary intervention: Insights from the European Association of Percutaneous Cardiovascular Interventions (EAPCI) Consensus","authors":"Dario Mafricaa, Luigi Spadafora, Kristian Galanti, Giuseppe Biondi-Zoccai, M. Bernardi","doi":"10.24969/hvt.2023.416","DOIUrl":"https://doi.org/10.24969/hvt.2023.416","url":null,"abstract":"The European Association of Percutaneous Cardiovascular Interventions (EAPCI) recently released a consensus statement on coronary physiology's role in managing percutaneous coronary interventions (PCI). Indeed, in recent years, significant advancements have been made in coronary imaging techniques, which have greatly improved our ability to assess stenosis features. Techniques like instantaneous wave-free ratio (iFR), fractional flow reserve (FFR), and longitudinal vessel analysis have evolved, providing insights into the hemodynamic significance of coronary lesions and guiding treatment decisions, particularly in PCI. This commentary aims to enlighten the critical issues of the EAPCI statement, briefly reviewing the main techniques for the study of coronary physiology and their applications.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76069949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Editor-in-Chief: On current issue, our SCOPUS metrics and databases, ICMJE updates on artificial intelligence in manuscript preparation, ESC 2023 congress trials, 2023 ESC and ACC/AHA guidelines and statement documents, long COVID","authors":"G. Kudaiberdieva","doi":"10.24969/hvt.2023.415","DOIUrl":"https://doi.org/10.24969/hvt.2023.415","url":null,"abstract":"","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90668843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on AHA Scientific Statement `Dual-Organ Transplantation: Indications, Evaluation, and Outcomes for Heart-Kidney and Heart-Liver Transplantation”","authors":"B. Todurov","doi":"10.24969/hvt.2023.414","DOIUrl":"https://doi.org/10.24969/hvt.2023.414","url":null,"abstract":"Recently published AHA Scientific Statement document “Dual-Organ Transplantation: Indications, Evaluation, and Outcomes for Heart-Kidney and Heart-Liver Transplantation: A Scientific Statement from the American Heart Association” has a detailed analysis of simultaneous heart transplantation along with kidney and liver transplantation (1). The combination of cardiac, renal and hepatic insufficiencies is quite common and is a challenge for transplant teams in all transplantation centers. The protocols and guidelines for transplantation of each individual organ are now well developed, but the indications and risk factors in simultaneous transplantations are always very personalized and difficult to systematize and summarize. In this article, the authors have managed to make a statistical analysis of the indications for surgery, analyze immune responses after dual-organ transplantation, compare different immunosuppression protocols, describe various techniques of simultaneous transplantation, and track immediate and long-term outcomes, all using a large clinical material. Based on this profound analysis, the authors make recommendations for a protocol of pre-surgery evaluation. Following the evaluation results, clear indications for heart-kidney and heart-liver transplantation are defined. Recommendations for induction and long-term immunosuppression are given. The authors also analyze organ allocation policies and the risks for unfair allocation, especially for kidney transplant candidates where the gap between the number of recipients and the number of transplantations is particularly large. Such allocation should be based on ethical principles of fairness and rational use of donor organs. Of particular interest in the article is Table 2, which shows unresolved issues and potential solutions of dualorgan transplantation. The lack of consensus for selection of patients for dual-organ transplantation remains an open issue and requires further resolution. Summarizing their study, the authors conclude that in the context of organ donor shortage, a very balanced selection of candidates for dual heart-kidney and heartliver transplantation should be made, keeping in mind that two recipients, each in need of only one organ, can be saved with these two organs. The article authors have certainly done a great analytical job in such a complex problem. The published results are especially helpful to those centers that are just starting their transplant program and have no experience of their own in dual-organ transplantations.","PeriodicalId":32453,"journal":{"name":"Heart Vessels and Transplantation","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79386348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}