Food ChemistryPub Date : 2025-05-02DOI: 10.1016/j.foodchem.2025.144603
Yu Hou, Marlize Z. Bekker, Tracey E. Siebert, David W. Jeffery
{"title":"Persistence of wine polysulfides: Investigation of the stability of isolated glutathione and cysteine species","authors":"Yu Hou, Marlize Z. Bekker, Tracey E. Siebert, David W. Jeffery","doi":"10.1016/j.foodchem.2025.144603","DOIUrl":"https://doi.org/10.1016/j.foodchem.2025.144603","url":null,"abstract":"Recent studies have highlighted that polysulfides formed from biological thiols (e.g., glutathione, GSH) and sulfhydryls like H<sub>2</sub>S may act as reservoirs of undesirable sulfur-like odours (SLOs) in wine. The conditions leading to appearance of SLOs are not fully understood and the reactivity of polysulfides was investigated in aqueous solutions, focusing on the stability and behaviour of GSH polysulfides (up to six sulfur atoms) and mixed cysteine (Cys) and GSH polysulfides (up to four sulfur atoms). Polysulfides were prepared and isolated via semi-preparative HPLC and studied at different temperatures (25, 35, and 40 °C) to investigate their dynamic behaviour. Results revealed that higher temperatures did not necessarily accelerate the degradation of polysulfides; longer-chain GSH pentasulfide and hexasulfide, as well as the mixed Cys-GSH trisulfide and tetrasulfide, were relatively stable. However, storing samples at −20 °C and subsequent defrosting affected all polysulfides. Initial polysulfide concentrations also appeared to influence degradation over time.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"48 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food ChemistryPub Date : 2025-05-02DOI: 10.1016/j.foodchem.2025.144610
Qianhui Yu, Tuoping Li, Suhong Li
{"title":"Interaction between wheat starch and hawthorn seed polysaccharide and its influence on starch properties and in vitro digestibility","authors":"Qianhui Yu, Tuoping Li, Suhong Li","doi":"10.1016/j.foodchem.2025.144610","DOIUrl":"10.1016/j.foodchem.2025.144610","url":null,"abstract":"<div><div>This study investigated the impact of alkaline extracted hawthorn seed polysaccharides (AHSP) on the properties and in vitro digestibility of wheat starch (WS) under <em>co</em>-heating and non-co-heating conditions. AHSP dose-dependently inhibited the hydrolysis of WS, with the 5 % AHSP co-heating treatment significantly reducing the degree of hydrolysis by 42.33 %. Correspondingly, the resistant starch (RS) content was increased with the increasing dose of AHSP, which demonstrated the effectiveness of co-heating interactions in reducing WS digestibility. The binding style was that AHSP bound to the linear chains of WS via physical forces, achieving a complexation index of 48 % (at 5 % AHSP), which inhibited the solubilization and facilitated the aggregation of WS. Additionally, the strong associative network between WS and AHSP increased apparent viscosity and enhanced the short-range ordered and crystalline structures of WS. These results provided a foundation for applying AHSP in developing starchy foods with low glycemic index (GI).</div></div>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"485 ","pages":"Article 144610"},"PeriodicalIF":8.5,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143900324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food ChemistryPub Date : 2025-05-02DOI: 10.1016/j.foodchem.2025.144618
Sisi Tang, Ruili Li, Shuting Huang, Qi Liu, Xiaoqing Chen
{"title":"Sensitive and selective simultaneous detection of ampicillin and chloramphenicol in foods with a SERS-activated molecularly imprinted capillary sensor","authors":"Sisi Tang, Ruili Li, Shuting Huang, Qi Liu, Xiaoqing Chen","doi":"10.1016/j.foodchem.2025.144618","DOIUrl":"https://doi.org/10.1016/j.foodchem.2025.144618","url":null,"abstract":"The specific identification and effective surface-enhanced Raman scattering (SERS) detection of multiple antibiotic residues in food samples remain challenging due to the interference of complex matrices and the low concentrations of the target analytes. Herein, we develop a novel sensor (SERS-CP-MI) that integrates SERS with molecular imprinting technology for sensitive and selective simultaneous detection of ampicillin (AMP) and chloramphenicol (CAP). The SERS-activated capillary (SERS-CP) utilizes capillary as carriers for plasmonic nanoparticles (Ag NPs) serving as recognition unit, where the modification of Ag NPs on the inner wall of the capillaries significantly enhances sensitivity. Meanwhile, the dual-template imprinted polymer (TMIP) was synthesized as capture unit through bulk polymerization and surface imprinting, forming specific cavities for simultaneous detection of AMP and CAP. The proposed method was successfully applied to chicken and milk samples, demonstrating that the SERS-CP-MI sensor is a reliable and effective tool for detecting antibiotic residues in food samples.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"44 1","pages":"144618"},"PeriodicalIF":8.8,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143901528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enzyme-assisted dynamic extraction as a promising method to produce high-quality fresh tea juice from summer tea leaves","authors":"Yuan-Chao Li, Yan-Qing Fu, Ying Gao, Jie-Qiong Wang, Shan Jin, Yanglong Liu, Jian-Xin Chen, Yong-Quan Xu","doi":"10.1016/j.foodchem.2025.144608","DOIUrl":"https://doi.org/10.1016/j.foodchem.2025.144608","url":null,"abstract":"To improve the flavor of green tea juice processed from summer tea leaves, the enzyme-assisted dynamic extraction method was applied. The chemical components and taste of fresh green tea juice prepared under different extraction conditions with enzyme treatment (EM: tannase or its combination with protease/cellulase/pectinase) were investigated. The results showed that EM could reduce the bitterness and astringency of the tea juice by up to 40 % and 39 %, and enhance the sweet aftertaste to 132 %. These improvements resulted from a significant decrease in ester catechins and an increase in non-ester catechins and gallic acid. In addition, it was also found that the tea juice extracted with EM had less sediment (73 %) and better stability. Therefore, combined dynamic extraction with EM for the extraction of green tea leaves could effectively improve the taste, and increase the extraction rate of tea juice, promoting the utilization rate of abandon-plucked tea leaves in summer.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"15 1","pages":"144608"},"PeriodicalIF":8.8,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143901525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Machine learning assisted nanozyme sensor array for accurate identification and discrimination of flavonoids in healthy tea","authors":"Zemin Ren, Qingxu Deng, Yu Wang, Yajun Yang, Hongbin Wang, Fufeng Liu, Wenjie Jing","doi":"10.1016/j.foodchem.2025.144612","DOIUrl":"https://doi.org/10.1016/j.foodchem.2025.144612","url":null,"abstract":"Identifying flavonoids in herbs is of great significance for elucidating their biological activity and pharmacological effects. However, distinguishing and detecting multiple flavonoids simultaneously remains a challenge. Here, an innovative citric acid-Cu (CA-Cu) nanozyme with peroxidase mimic (POD) and laccase mimic (LAC) activities was successfully synthesized. Due to the varying inhibitory effects of flavonoids on CA-Cu dual-enzyme mimicking activities, and the degree of inhibition increasing with prolonged reaction time, a nanozyme sensor array was constructed based on reaction kinetics and applied to the identification of five flavonoids. This technique further streamlines the building of sensing channels. Moreover, by integrating various machine learning algorithms with the sensor arrays, accurate identification and prediction of five flavonoids in multiple herb samples have been successfully achieved. Finally, the sensor array successfully achieved the differentiation and recognition of multiple healthy tea, demonstrating its feasibility in efficiently distinguishing and detecting flavonoids in complex samples.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"22 1","pages":"144612"},"PeriodicalIF":8.8,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143901521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation, identification, and molecular mechanism of novel DPP-IV inhibitory peptides from pumpkin seed: In silico screening and experimental validation","authors":"Xiya Chen, Wenhao Zhang, Yuexin Pan, Jia Ran, Xia Liu, Xiaodong Yu, Qiyi He","doi":"10.1016/j.foodchem.2025.144530","DOIUrl":"https://doi.org/10.1016/j.foodchem.2025.144530","url":null,"abstract":"The rising prevalence of Type 2 diabetes mellitus (T2DM) and the limitations of synthetic DPP-IV inhibitors emphasize the need for natural alternatives with fewer side effects. This study explored pumpkin seed protein (PSP) as a source of potential DPP-IV inhibitory peptides. Through in silico screening and experimental validation, seven novel peptides were identified, with LPGFF, LPGF, and MPLPA exhibiting potent inhibitory activities (IC<sub>50</sub>: 449.68–478.88 μM). Molecular docking and dynamics simulations revealed stable binding to DPP-IV's active site, interacting with key residues (Tyr547, Ser630, Tyr662, Arg125, Glu205). Kinetic analysis indicated competitive inhibition. In vivo studies in C57BL/6 J mice demonstrated significant hypoglycemic effects, reducing blood glucose AUC by 14.98–18.65 % at 100 mg/kg. The peptides also exhibited stability under varying temperatures, pH, and gastrointestinal conditions. These findings position PSP as a promising source of DPP-IV inhibitors and highlight the potential of in silico screening for bioactive peptide discovery in T2DM management.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"1 1","pages":"144530"},"PeriodicalIF":8.8,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143901522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Food ChemistryPub Date : 2025-05-01DOI: 10.1016/j.foodchem.2025.144591
Jue Liu , Youjun Hu , Jie Zheng , Pan Yue , Shi-Yi Ou , Jiaqi Lu , Xiting Huang , Wanyi Cao , Hua Zhou
{"title":"Preliminary exploration of the loss of free Methylselenocysteine during selenium-rich tea processing","authors":"Jue Liu , Youjun Hu , Jie Zheng , Pan Yue , Shi-Yi Ou , Jiaqi Lu , Xiting Huang , Wanyi Cao , Hua Zhou","doi":"10.1016/j.foodchem.2025.144591","DOIUrl":"10.1016/j.foodchem.2025.144591","url":null,"abstract":"<div><div>Methylselenocysteine (SeMC), the primary organic selenium in tea, enhances human nutrition through its bioavailability and bioactivity (e.g. antioxidant activity). This study investigated SeMC stability during tea processing: high-temperature fixation caused 48.11 % SeMC loss (vs. 25.54 % when rolling at 25 °C), following first-order kinetics (<em>Ea</em> = 65.58<!--> <!-->kJ/mol, air). Nitrogen protection reduced degradation to <10 % at 150 °C. We first report that 29.19 % of oxidised SeMC (SeMCO) regenerates to SeMC at 25 °C, challenging the assumed irreversibility of selenium oxidation. Catalase (≥200 U/mg) synergized with nitrogen to inhibit oxidation, enabling 1) shortened thermal exposure, 2) nitrogen blanketing, and 3) enzymatic control. These results provide practical solutions to preserve selenium functionality during tea processing, thus advancing selenium-rich food production.</div></div>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"485 ","pages":"Article 144591"},"PeriodicalIF":8.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143893805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Controlled release of caffeine from oat globulin nanocomplexes: Biocompatibility and gastrointestinal dynamics","authors":"Junyu Lin, Hanhan Liu, Jianyu Yang, Yang Gao, Guanghua Zhao, Chenyan Lv","doi":"10.1016/j.foodchem.2025.144587","DOIUrl":"https://doi.org/10.1016/j.foodchem.2025.144587","url":null,"abstract":"Caffeine, a widely consumed stimulant, is known for its rapid absorption and clearance, leading to fluctuations in plasma concentration and potential gastrointestinal irritation. This study explored the interaction between oat globulin (OG) and caffeine, focusing on OG's ability to stabilize caffeine's release and bioavailability. Fluorescence quenching, FTIR and molecular docking indicated that each OG molecule is capable of binding 8.32 ± 1.59 molecules of caffeine with a high affinity. <em>In vitro</em> digestion simulations demonstrated slower caffeine release from the OG-caffeine nanocomplex, reducing toxicity to gastric epithelial cells (GES-1). <em>In vivo</em> studies showed that the OG-caffeine nanocomplex lowered the peak plasma concentration (C<sub>max</sub> = 1.761 ± 0.367 μg/mL) and extended the half-life of caffeine (T<sub>1/2</sub> = 62.159 ± 7.156 min), enhancing its sustained effect. Additionally, cytotoxicity assays revealed that the OG-caffeine nanocomplex exhibited improved biocompatibility, reducing the irritant effects of caffeine on GES-1 cells. This study highlights the novel application of plant-based OG as an effective carrier to improve the delivery and safety of caffeine without synthetic additives.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"1 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preparation, characterization and co-pigmentation mechanism of high stability indicator films: Anthocyanins and oxalic acid","authors":"Chunyan Jiang, Xiaoyu Li, Yue Zhao, Hongdong Deng, Cheng Li, Caixia Wang, Yuhang Su, Saiyan Chen","doi":"10.1016/j.foodchem.2025.144561","DOIUrl":"https://doi.org/10.1016/j.foodchem.2025.144561","url":null,"abstract":"A Roselle anthocyanin extract (RAE)-oxalic acid (OA) co-pigment indicator was synthesized and incorporated in indicator films. OA was selected as a co-pigment due to its unique conjugated structure and strong intermolecular interactions to improve stability of RAE. First, RAE was screened based on its lowest fading rate (22.20 %) and highest <em>a</em> value (40). Furthermore, the optimal mass ratio of RAE to OA was determined to be 2:1, as it resulted in minimal color change and absorbance reduction. The co-pigmentation mechanism of RAE-OA was subsequently elucidated through molecular docking simulations before being further confirmed by FT-IR and <sup>1</sup>H NMR spectroscopy. Finally, when pH variation exceeded 1, ΔΕ was more than 5 (compared to the original film). Additionally, the ammonia sensitivity achieved a score of 36.32 points in the sRGB evaluation system, with a shelf-life over 60 days. Overall, the RAE-OA film highlighted considerable potential for real-time food freshness monitoring.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"12 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling the differences between vitexin and isovitexin: From the perspective of sources, green advanced extraction technologies, biological activities, and safety","authors":"Jinquan Lin, Hao Ran, Qiqian Feng, Qun Shen, Sumei Zhou, Yuanlin Sun, Dianzhi Hou","doi":"10.1016/j.foodchem.2025.144600","DOIUrl":"https://doi.org/10.1016/j.foodchem.2025.144600","url":null,"abstract":"Vitexin and isovitexin, as the two of representative flavonoid C-glycosides, are naturally occurring bioactive compounds predominantly found in food plants. Their multiple pharmacological activities have generated a lot of interest in their application in disease management. However, as isomers, vitexin and isovitexin show differences between them in various aspects. To achieve their personalized application in precision nutrition, further research is needed to reveal their differences. Based on the various sources and distribution of vitexin and isovitexin, the advantages and limitations of various green advanced extraction technologies are discussed to improve their purity and activity. Furthermore, vitexin and isovitexin exhibit shared and diverse health benefits from the perspective of <em>in vitro</em> and <em>in vivo</em> research reports. This review contributes to a better understanding of the sustainable production of natural vitexin and isovitexin based on their differences, thus promoting the personalized application of them in the functional foods or pharmaceutical industries.","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"34 1","pages":""},"PeriodicalIF":8.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143897633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}