Scholars International Journal of Anatomy and Physiology最新文献

{"title":"Investigation of Physiologic Effect of Prolonged Consumption of Raphia Hookeri Fruits Pulp Aqueous Extract on Renal Functions of Male Wistar Rats","authors":"Egbono Frank Fubara, Ekoriko P. I., N. M","doi":"10.36348/sijap.2023.v06i07.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i07.001","url":null,"abstract":"The aim of this study is to investigate the physiologic effect of prolonged consumption of Raphia Hookeri fruits pulp aqueous extract on renal functions of male wistar rats. A total of 32 male wistar rats of weight ranging from 130gram to 200grams were used. The extract was administered orally for each 4 groups except control (group1) for twenty-eight (28) days. Group 1 rats were given animal feed and water only, group 2 were given 500mg/kg body weight of the extract, group 3 were given 1000mg/kg body weight of the extract, group 4 were given 2000mg/kg body weight of extract. The statistical analysis done using mean and standard deviation, P value at ≤ 0.05 and results showed that the sodium ion levels in all the test groups were marginally raised when compared to group 1, potassium ion levels in all test groups had only non-significant variations when compared to both the control and test groups but in test groups were seen to be slightly reduced with respect to group 1. Groups 2, 3 and 4 indicated elevated bicarbonate ion but of all, it was most and significant in group 4 when compared to group 1. Chloride ion indicated non-uniform and non-significant changes when compared to both the control and test groups. Creatinine all indicates non-significant effects of the extract when compared to group 1. The increase observed in urea and creatinine indicates that kidney function would deteriorate as it prolongs which negatively alter the renal physiology of the male wistar rats.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115272409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Atherogenic Lipid Profile amongst Obese Women Resident in Rivers State, Nigeria","authors":"Tamuno-Opubo A., Ojeka S. O., Dapper D. V","doi":"10.36348/sijap.2023.v06i05.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i05.001","url":null,"abstract":"Increasing incidences of obesity are widely and significantly connected to the risks of cardiovascular/coronary heart diseases, hypertension, stroke, etc. However, prevalence of obesity contrasts by genetic, gender and inter/intra population factors. The present study thus investigated the changes in atherogenic lipid profile in obese women resident in Rivers State. A minimum sample size of 272 was determined using the Leslie Fischer's formula; precisely 334 obese and non-obese women within their 18 and 65 years of age with no critical health condition and resident in Upland and Riverine areas of Rivers State were actually surveyed by the present study. A multistage sampling technique was adopted, and subjects were recruited across the upland and riverine locations of the State. These subjects were uniformly drawn from the multi-ethnic residents of the state. Anthropometric (body mass index-BMI) data and blood sample (via antecubital vein following standard procedures) were obtained from the consenting subjects. After laboratory analyses, the numerical data were subjected to statistical analyses using the statistical package for social sciences (SPSS) version 21.0. One-way analysis of variance (ANOVA) and independent t-test with a p< 0.05 considered statistically significant were determined. Virtually all atherogenic lipid profile markers evaluated in the present study [TC, TG, and LDL-C, Castelli risk index (CRI), atherogenic index of plasma (AIP) and AC atherogenic coefficient (AC)] were significantly (p<0.05) higher in the obese subjects compared to those of the non-obese. And the values were even higher in the riverine obese subjects than in those of their upland counterparts. In conclusion, the outcome of the present study indicates possible existence of intra-cultural or intra-population distinctions that may be responsible for the severer atherogenic lipid profile of the obese subjects, (particularly amongst the riverine subjects). The likely imminent grave health risks (like coronary artery diseases, cardiovascular diseases and atherosclerotic, etc.) amongst the subjects (mainly the riverine residents) must be checked and properly managed at the levels of the individual, caregiver and government/regulators, in order to consciously reduce the huge health burden of obesity in our populace.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114974190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Wormian Bones in Dry Adult Human Skull in University of Port Harcourt and Rivers State University","authors":"A. A., J. W., Ajie P. C., Victor P. D., Horsefall U. A., Eyinda B., Okpara P. E., R. E., Dan-Jumbo T., Tee G. P.","doi":"10.36348/sijap.2023.v06i04.003","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i04.003","url":null,"abstract":"Wormian bones, otherwise ‘Sutural’ bones, are accessory bones within or near cranial sutures. They are mostly found on lambdoid sutures and can be one or more in each suture. This study is aimed at examining the incidence and frequency of Wormian bones in the dry adult cadaveric skull in Rivers State, Nigeria. Forty-three (43) dry adult skulls were examined for the presence, number, and location of Wormian bone. Thirty-seven (37) of the skulls were from the osteological collections of the Department of Human Anatomy, Faculty of Basic Medical Sciences, College of Health Science, University of Port Harcourt, and six (6) from the osteological collections of the Department of Human Anatomy, Faculty of Basic Medical Sciences, College of Medical Sciences, Rivers State University. 13 (30.23%) of the calvarias had Wormian bones while sutural bones were absent in 30 (69.77%0). 8 (61.53%) calvarias with Wormian bones had sutural bones in the lambdoid suture; with 3 (23.08%) on the left arm and 5 (38.46%) on the right arm of the lambdoid suture. 2 (15.38%) of the calvarias with Wormian bone had sutural bone in the sagittal suture and 3 (23.08%) had Wormian bones in the lambda (Inca bone). The knowledge of incidence of Wormian bone and their calvaric distribution as described in this study is essentially useful to the Anatomist, Radiologist, Pediatrician, and Surgeon in their daily practice, as well as in forensic medicine.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"4 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123636498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex and Age Estimation using the Morphometric Assessment of the Femur","authors":"C. Orupabo, L. Oghenemavwe, B. Didia","doi":"10.36348/sijap.2023.v06i04.002","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i04.002","url":null,"abstract":"Anthropological assessment becomes the sole available medium for identification of the deceased in most forensic cases. We hope therefore to assess metrically if the femur bone could be used to estimate the age and sex of individuals by focusing on some rare morphological parameters. The skeletal samples of the right femur from 105 individuals (78 males and 27 females), who are within the age range of 21 and 60 years were harvested. The male samples had 53 profiled and 25 specimens non-profiled for age, while the females had 10 profiled and 17 specimens non- profiled for age. Direct measurements were taken for the marrow cavity diameter (MCD) and cortical thickness or radius (CT or Cr) using a centimeter rule and a sliding digital caliper to the nearest 0.1mm.The Marrow Cavity Diameter in our study is higher in the male population (1.70± 0.05) than the female population (1.43± 0.05). This variation was statistically significant (P<0.05) using the student t-test. The radius or thickness of the cortex decreases with age in females but is higher in the female population (0.73±0.03) than the males (0.68±0.03). ANOVA shows that there is a significant variation across male age groups (P=0.00) for the MCD, MA and Area of cortex. The marrow cavity diameter increases with age in males while area of cortex reduces with age in females. It is imperative therefore that the marrow cavity diameter, the medullary area and area of cortex are good assessors of age and sex.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127801334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effects of Extracts of Laurus nobilis on some Biochemical Parameters of Wistar Rats","authors":"","doi":"10.36348/sijap.2023.v06i04.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i04.001","url":null,"abstract":"Laurus nobilis is one of the most popular species belonging to the lauraceae family and it has been reported to possess many physiological properties such as antimicrobial, antifungal and wound healing effects. In this study, effects of ethanolic leaf extract of Laurus nobilis on some oxidative stress markers and liver function parameters of female Wistar rats were investigated. Five rats were randomly assigned into each of groups 1-4, of which group one (1) served as control and received distilled water. Groups 2-4 were treated with 100mg/kg bw, 200mg/kg bw and 400mg/kg bw of the ethanolic extract of the leaves of Laurus nobilis respectively, for a period of 14 days. The results obtained indicated that the superoxide dismutase and catalase enzyme activities as well as, gluthathione reductase and peroxidase activities were not significantly affected. The malondialdehyde level did not change significantly after two weeks of extract administration. The extract caused no significant (P<0.05) alteration in the enzyme activities of alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), as well as serum concentrations of total protein (TP), albumin (ALB) and total bilirubin. This study have shown that extract of Laurus nobilis neither altered hepatic function parameters nor promoted toxic stress in the female Wistar rats.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121221601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Monosodium Glutamate Ingestion on Spatial Memory and Cognitive Behaviour in Wistar Rats","authors":"Austin A. Ajah, V. O. Hart","doi":"10.36348/sijap.2023.v06i03.002","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i03.002","url":null,"abstract":"Monosodium glutamate (MSG), one of the most widely used food-additives in commercial foods gives a special aroma (umami) to processed foods. It’s vital to brain metabolism and function. Adverse effects of MSG have been widely reported. However, there is scarcity of literature on the action of MSG on spatial memory and cognition. Hence, there is need to assess the effect of MSG ingestion on spatial memory and cognitive behavior in Wistar rats. 25 Wistar rats were randomly selected into five groups and treated for three weeks thus: Group 1 (control), Group 2 (0.7 mL MSG), Group 3 (1 mL MSG), Group 4 (1.5 mL MSG) Group 5 (0.1 mL Epinephrine). Neurobehavioral (Barnes, navigation, and handgrip) activities exhibited by the various groups were recorded and analyzed using ANOVA. In the Barnes maze test, there was a significant decrease (p<0.05) in escape time in group 4 when compared to the control for weeks 1 and 3. In week 1 of the Navigation maze test, group 4 animals spent less time (p<0.05) to navigate the maze when compared to the control. In week 1 and 3 of the handgrip test, animals in groups 2, 3 and 5 had a significant decline (p<0.05) in grip strength when compared to the control group; However, in week 2, only the animals in group 5 had a decline in grip strength (p<0.05) when compared to control. MSG did not cause any form of neurotoxicity, cognitive or motor decline in rats.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"255 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122879634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Ethanolic Extract of Premature Carica papaya (Pawpaw) Fruits on the Reproductive System of Female Wistar Rats","authors":"Victor P. D., O. S., Ogaree T. B, Nkoju, T. C., A. T., Ajie P. C., Wami-Amadi C. F., Okpara P. E., R. E., Ekokodje J. W., Dan-Jumbo D., Tee G. P., Jaja N. B.","doi":"10.36348/sijap.2023.v06i03.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i03.001","url":null,"abstract":"In recent times, different plant extracts have been reported to exert fertility enhancing effects. Carica papaya fruit is known for its use in preparation of herbal remedies. The aim of this study is to investigate the effects of Carica papaya on the reproductive system of female Wistar rats. Sixteen (16) female Wistar rats with regular oestrous cycle were used for this study. Animals were grouped into four (4) groups (control, low dose, middle dose, and high dose) of 4 animals each. Carica papaya fruit extract was administered for 14 days while monitoring the oestrous cycle. Twenty hours after the last administration, animals were sacrificed, and blood samples taken. Blood samples were collected for hormonal assay. Data obtained was expressed as Mean ± standard deviation, values were considered statistically significant when P ≤ 0.05. Phytochemical analysis of premature Carica papaya fruit revealed the presence of alkaloids, terpenes, sterols and terpenoids were heavily present. Estrous cycle was not altered. Serum FSH and LH increased. The extract is likely to possess fertility enhancing properties.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122131617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orbitofacial Photometric Analysis in Nigerian Children","authors":"O. Ozioko, O. Egwu, E. Finbarrs-Bello","doi":"10.36348/sijap.2023.v06i02.002","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i02.002","url":null,"abstract":"Aim: This study was conducted to gather data on the normal measurements of facial features in healthy children from South-East Nigeria. The aim was to measure the distance between the pupils (IPD), the distance between the inner corners of the eyes (ICD), and the distance between the outer corners of the eyes (OCD) in order to establish a reference for ophthalmological assessments and diagnoses. The study was based on the understanding that these orbitofacial measurements and canthal indices are important tools for anatomists and craniofacial surgeons in evaluating systemic syndromes, craniofacial abnormalities, and post-traumatic telecanthus. Method: A sample of 120 healthy subjects within the age range of 1 to 5 years was enrolled in this study. The photographs of the face were captured non- invasively using a Nikon D 90 camera, orbitofacial landmarks were identified and measured using Image J Software. The data was then analyzed to determine the normal measurements for these facial features in healthy children from South- East Nigeria. Results: showed that all parameters measured (IPD, ICD, OCD) were higher in females than in males, but the difference was not statistically significant. Conclusion: The study presents a primary data base for orbitofacial anthropometric indices of children in South-East Nigerian which can be used as a reference for ophthalmological assessments and diagnoses. This data can be used to aid in the diagnosis of craniofacial abnormalities and post-traumatic telecanthus, as well as to evaluate systemic syndromes. Additionally, this study can be used as a benchmark for future studies on this topic in the same population or other population as well.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116194215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiothoracic Ratio, Vertical Height, Transverse Dimension of the Trachea of Nigerians Resident Port Harcourt, Rivers State, Nigeria","authors":"S. C. Okoseimiema, C. Agi","doi":"10.36348/sijap.2023.v06i02.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i02.001","url":null,"abstract":"Introduction: Cardiothoracic ratio and vertical height are important indicators of cardiac size. The chest radiograph provides excellent contrast between the air-filled, cardiac, and aortic outlines. Aim of the study: This study was aimed at determining the cardiothoracic ratio, vertical height, transverse dimension of the trachea of Nigerians resident in Port Harcourt. Materials and Methods: This was a retrospective descriptive study carried out in the Radiology Department of the University of Port Harcourt Teaching Hospital, Rivers State. The study duration was 8 months (January–September, 2021), which involved four hundred and forty-eight (216 males and 232 females) normal chest radiographs of adult Rivers aged between 18 and above. The radiographs were found to be normal by a qualified radiologist in the department. Random sampling was used to determine the sample size for the study. Results and Discussions: Males [VH(cm) 1.49±0.40; TDT(cm) 20.20±2.81; ACR(cm) 0.46±0.068]; females [VH(cm) 19.08±2.58; ACR(cm) 0.48±0.06; CTR (cm) 41.44±3.40]. The males had repeatedly higher values vertical height and cardiothoracic ratio than the females, while the females had a higher value for aorto-cardiac ratio. Conclusions: The values of vertical height, cardiothoracic ratio, transverse dimension of trachea, and aorto-cardiac ratio demonstrated sexual dimorphism, the males had consistently higher values than the females except for aorto-cardiac ratio.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129452785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological and Morphometric Study of Glenoid Cavity and It’s Clinical Application in Western Rajasthan Population","authors":"Kataria Sushma K, S. Manu, Gehlot Kalpana, Goyal Samata","doi":"10.36348/sijap.2023.v06i01.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i01.001","url":null,"abstract":"Background: Glenoid cavity (GC) is a shallow, concave and oval fossa at superolateral border of scapula and form glenohumeral joint with scapula. There is a notch present on its anterosuperior part which gives its different shape. When this glenoid notch is indistinct its shape is pear shaped, when it is distinct it looks like inverted comma shape and when it is absent its oval shape. Understanding morphometric and morphological variation of GC plays an important role for surgeon while designing and fitting of glenoid component for total shoulder arthroplasty. Aims: A morphometric study of the glenoid cavity of 120 adult dry human scapulae in Western Rajasthan Population was done to evaluate the shape and various diameters of the GC. Material and methods: 120 dry scapulae (60 Right and 60 Left) of unknown sex, were taken for the study. Damaged bones were excluded from the study. Supero-Inferior Diameter (SI-D), Antero-Posterior Diameters (AP-D1 and AP-D2) of both sides were analysed and compared by unpaired t-test. Results: Most common shape of GC was pear shaped (45.83%) followed by oval shape (35%). Least common shape was inverted comma shape (19.16%). Difference in mean SI-D of both sides were statistically insignificant while AP-D1 and AP-D2 were found statistically significant. Mean Glenoid Cavity Index on right and left sides were 64.57 ± 6.91% and 68.33 ± 6.29% respectively. Conclusions: The above study helps Orthopedicians in shoulder dislocation, fractures and treating shoulder pathological conditions like glenohumeral instability and rotator cuff pathology.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133944387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}