Scholars International Journal of Anatomy and Physiology最新文献

{"title":"Correlation of Indices of Obesity with Hypertension among Igbos in Enugu Metropolis","authors":"Maxwell Ubanagu Odumeh, Chike I. P. Anibeze, Emmanuel Anayochukwu Esom, Rosemary Ngozi Njeze, Nto Johnson Nto, Elizabeth Finbarrs- Bello, Emeka Mgbe, Nneka Iloanusi","doi":"10.36348/sijap.2023.v06i10.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i10.001","url":null,"abstract":"Background: Relationship between obesity and hypertension is well established and hypertension shows positive relationship with all obesity indices. Objective: To determine the obesity indicator with the greatest sensitivity in predicting hypertension. Method: A cross-sectional community-based descriptive survey was carried out in Enugu Metropolis. Multistage sampling procedures were used to select participants using the World Health Organization STEPS instrument. Height, weight, waist circumference; hip circumference and blood pressure were measured and recorded. Results: A total of 482 participants were recruited; of which 160 (33.2%) and 322 (66.8%) were males and females respectively. 89 (18.5%) participants have high systolic blood pressure, 117(24.3%) have high diastolic blood pressure, while the overall hypertension prevalence is seen in 123 participants (25.5%). The blood pressure was noticed to increase as obesity increases regardless of the index of obesity used and that at WHR≥1 all the 15 participants (M:8, F:7m) that crossed that threshold were hypertensive regardless of age and sex demonstrating the sensitivity of WHR in predicting hypertension and associated cardiometabolic risks. Conclusion: obesity and hypertension are interrelated and common in our environment, all the indices of obesity show positive correlation with hypertension but WHR offers a simple index that can be used to detect occult hypertension in our clinics due its 100% correlation at the WHR threshold of ≥1.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135546933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haemorrheological Proprties of Blood in Phases of Menstrual Cycle in Female Undergraduate Students in Port Harcourt, Nigeria","authors":"Abiye Tamuno- Opubo, Rosemary Oluchi Stanley, Joy Tonye Wihioka, Zosa Ugbana Deinye, Siyeofori Belema Dede, Jerry Dumley Nwiyor, Sophia Chimenem Akah","doi":"10.36348/sijap.2023.v06i09.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i09.001","url":null,"abstract":"Background: Blood flow pattern among various women in different location of the world had been noted to vary significantly with some anthropometric variations, geospatial locations, age, BMI and cardiovascular parameters. As a result, this study therefore investigated the flow properties of blood during menstrual cycle in female undergraduate students in Port Harcourt as a baseline study with a view of establishing local reference data for Port Harcourt, Nigeria. Materials and Methods: 125 volunteers were recruited into the study using stratified random sampling techniques and were administered well-structured questionnaires. Their blood samples were collected and haemorheological properties (Whole Blood Viscosity, Plasma Viscosity, ESR and haematocrits) were analysed against various phases of menstrual cycle namely: menstruation, follicular, ovulation and luteal phases among female undergraduate students in Port Harcourt. Results and Discussions: Result of the study when compared with the WHO standard references showed a significant (ρ≤0.05) difference in ESR, PV, WBV and ESR for menstruation and follicular phases while HCT was not significant with ovulation and luteal phases. Flow properties was also significant (ρ≤0.05) with ages (16-23, 24-30 and ≥31) years as compared with the WHO Control. BMI and blood pressure was also significant (ρ≤0.05) with Haemorrheological properties of blood. Conclusion: The study therefore concluded that there is a significant (ρ≤0.05) correlation between flow properties of blood and phases of menstrual cycle among university students in Port Harcourt, Nigeria as compared with the WHO standard values.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"79 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136010893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Waist to Height Ratio a reliable Indicator of Obesity in Igbos of Enugu Metropolis","authors":"Maxwell Ubanagu Odumeh, C. Anibeze, Rosemary Ngozi Njeze, N. Nto, E. Bello, E. Mgbe, N. Iloanusi","doi":"10.36348/sijap.2023.v06i08.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i08.001","url":null,"abstract":"Background: Obesity could be generalized or truncal/android and most of the pathologies linked to obesity is with the android obesity. There is multiplicity of indices for measuring obesity hence the need for simple but sensitive and accurate index of assessing obesity. Objective: the aim was to determine the index that is simple, accurate and sensitive in detecting obesity. Method: A cross-sectional community-based descriptive survey was carried out in Enugu Metropolis. Multistage sampling procedures were used to select participants using the World Health Organization STEPS instrument. Ethical approval and consents were duly and respectively obtained from the Ethics Committee of the Enugu state university of science and technology Enugu. The data obtained were coded and analyzed into frequencies, percentages and mean using the Statistical Package for Social Sciences (SPSS) version 17. Chi-square (x) test was used to compare categorical variables for associations while multi-nominal logistic regression was used to examine correlates. Statistical significance is set at p< 0.05 and 95% confidence interval. Result: A total of 482 participants were recruited; of which, 33.2% and 66.8% were males and females respectively. By BMI, 95(19.7%) were obese; 180(37.3%) were considered obese by WHR; 94(19.5%) were obese by %body fat; while 214(44.4%) were obese by WC and 230(47.7%) were obese by WHtR. Conclusion: The superiority of WHtR in detecting obesity is clearly demonstrated in this study and this can easily be applied in our clinics.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121632205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collateral Artery from the 1st Part of the Axillary Artery: A Case Report","authors":"J. Srinivasan, R. N, Dinesh Kumar V","doi":"10.36348/sijap.2023.v06i07.006","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i07.006","url":null,"abstract":"During radiological studies and surgeries, the branch architecture of the Axillary artery (AA) is crucial. Variations can complicate the interpretation of radiological data and cause unanticipated surgical complications. In the present situation, an uncommon collateral artery arose from the 1st part of the AA and gave rise to the lateral thoracic artery (LTA) and subscapular artery (SSA) before becoming the posterior circumflex humeral artery (PCHA). The SSA additionally gave rise to the thoracodorsal (TDA) and circumflex scapular arteries (CSA). For safe and effective surgical treatments and to prevent technical failures during catheterization and interventional procedures, it is essential to be aware of these anatomical differences.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114487405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Physiological Effects of Drop Set on IGF and GH in the Quadriceps Femoris Among Males in Kakamega County, Kenya","authors":"Robert Ouma Namango, N. Magak, K. Onyango","doi":"10.36348/sijap.2023.v06i07.005","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i07.005","url":null,"abstract":"Background: Resistance training (RT) for muscle growth (hypertrophy training – HT) theoretically optimizes the mechanical tension placed on the working muscle, which may be key to activating hypertrophic mechanisms. After prolonged HT, specialized weightlifting techniques like drop set training (DS) – or lifting progressively reduced loads without recovery – may help overcome plateaus in strength and re-stimulate hypertrophy, but physiological evidence to potentially support this hypothesis or the efficacy of implementing an acute drop set protocol in comparison to maintaining a standard hypertrophy training program is lacking. Objective: This objective of this study was to assess the levels of plasma growth hormone, and IGF during drop set and concentric exercises. Methods: The study used a randomized controlled, counterbalanced, repeated measures design. A repeated measures design was used to minimize the inter-individual variability of the hypertrophic response to resistance training. Thirty young males participated in a randomized, counterbalanced, within-subjects design, a DS protocol (4 sets, 4 loads/set, 75-30% 1RM, minimal recovery between loads, 3-minute recovery intervals between sets) and, separated by at least 7 days, a HT protocol (4 sets, 75% 1RM, 3-minute recovery intervals between sets). Data was analyzed using a 2 (Training Type: DS, HT, levels of quadriceps muscle hypertrophy) ´ 2 (Time: pre-exercise, post-exercise) repeated measures ANOVA to test the differences in concentrations of IGF-1 and GH during DS and HT at the specified time points. Results: The study found that there was a significant difference in IGF 1 levels before and after the exercise for both groups (Drop set and concentric exercise), with a p-value of .007. The interaction effect between the within-subjects factor (IGF 1 pre and post) and group was also significant. The results showed that there was a significant difference in GH levels before and after the exercise for both groups (Drop set and concentric exercise), with a p-value of < .001. For the Drop set group, GH pre was also significantly lower than GH post. It can be concluded that both the drop set and concentric exercise techniques have an impact on the levels of IGF 1, and GH in the quadriceps femoris. The study recommends that physical trainers and fitness professionals should consider using the Drop set exercise technique in their training programs for clients who are looking to improve their performance.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115614418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Serological and Morphogenetic Variability among Students in Federal Polytechnic, Ile-Oluji, Ondo State","authors":"M. O. Yekeen, S. Umar, Abdolzadeh Ahmad","doi":"10.36348/sijap.2023.v06i07.004","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i07.004","url":null,"abstract":"Background: Human beings, like all living organisms, are characterized by the presence of genetically inherited physical and/or physiological characters which made them to be genetically distinct from each other. These traits, known as morphogenetic traits, are transmitted in autosomal dominant or recessive fashion. This study strives to determine the distribution, association and inheritance pattern of morphogenetic characters among students of Federal Polytechnic Ile-Oluji, Ondo State, Nigeria. Materials and Methods: A random sample of four hundred (male 219 and female 181) students were evaluated for two serological (blood group and rhesus factor) and ten morphogenetic traits including, earlobe attachment, bent little finger, widow’s peak, hitchhiker’s thumb, tongue rolling, tongue flipping, cleft chin, mid-phalangeal hair, eye colour and polydactyly. The data obtained were expressed in simple percentages. Chi- square analysis was used to test for statistically significant associations between observed allelic and genotypic frequency at 5% level of significance. Results and Discussions: The study revealed Blood group O as the most prevalent (47%) followed by A (22.75%), B (18.5%) while the least was AB (11.75%). Over 91% of these population were Rh (D) positive while over 8% were Rh (D) negative. The other genetic traits were observed in frequencies; attached earlobe (57.25%), bent little finger (27.5%), widow’s peak (34.25%), hitchhiker’s thumb (65.75%), tongue rolling (54.25%), tongue flipping (23%), cleft chin (24%), mid-digital hair (42%), dark eye colour (31%) and polydactyly (26.75%). Association analysis showed the presence of association between gender and all the traits excepting widow’s peak (χ2 = 19.7, p = 0.000), cleft chin (χ2 = 11.5, p = 0.000) and polydactyl (χ2 = 12.2, p = 0.000). Conclusion: Recessive traits were much more prevalent in the sampled population. The results obtained established baseline data for this population, and it can be used for medically, legally and also for anthropological studies.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125647558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Soya Beans and Brown Beans in Degenerative Changes Expressed in Cortical Neun Immunoreactivity in a Casava-Induced Konzo Disease Rat Model","authors":"Okakpu Evangeline Ebelechukwu, David Lekpa Kingdom, Okoseimiema Sonny Clement","doi":"10.36348/sijap.2023.v06i07.003","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i07.003","url":null,"abstract":"Background: Konzo is related to a habit of long-term consumption of cassava; it is a chronic disease with quite different symptoms from acute cassava poisoning. The ameliorative effect of soya beans and brown beans in degenerative changes expressed in cortical NeuN immunoreactivity in a konzo disease rat model was investigated in the present study. Materials and Methods: 30 male wistar rats weighing 200-250g were assigned to Group 1 (Control, n=5) and was fed on animal pellet, whereas Group 2 (Protein, n=5) was administered with protein food (Soya beans+Brown bean). Bitter cassava flour was provided to Group 3 (cassava-induced Konzo, n=15). Protein (Soya beans+Brown bean) and bitter cassava flour were administered to Group 4 (protein treatment group, n=5). The Cerebrum (primary motor cortex) region was harvested through transcardiac perfusion for histological and immunohistochemical staining. Image J was used to quantify the neurons in the motor cortex. We examined general structures in the primary motor cortex with hematoxylin and eosin (H&E) stain. Result and Discussion: H&E demonstration showed distinct pyramidal neurons with large round nucleus, and prominent nucleoli in the Control group. Interspersed between the pyramidal neurons were numerous glia cells. Protein (Soya beans+Brown bean) group, Cassava group, and Cassava + Protein group also showed intact histology of the cortex compared to control usig H&E stain. NeuN stains analyzed immunoreactive neurons. The rats fed on cassava showed significant decrease in the NeuN immunoreactive neurons at ***[p<.001] compared to the Control and Protein administered group, whereas Cassava + Protein groups showed decrease NeuN immunoreactive neurons at**p<0.1 compared to Protein group(Soya beans+Brown bean). Conclusions: This study has provided an empirical data on the ameliorative effect of soya beans and brown beans supplement on Cassava-induced konzo disease animal model. This data will be very useful to Anatomists, konzo researchers and neuroscientist.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"3 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133169408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude and Practice of Edutainment among Anatomy Educators: A Nigerian Survey","authors":"O. Egwu, Uloaku Akubueze Nto- Ezimah, N. Nto, Eneje Ifunanya, Chioma Ekenna- Ohanenye","doi":"10.36348/sijap.2023.v06i07.002","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i07.002","url":null,"abstract":"Background: It is well known that education and learning can be linked with lucid, playful and pleasurable experiences. Aim: This study evaluated the knowledge, attitude and practice of edutainment among anatomy educators. Methods: The study was conducted among Anatomy educators in four Colleges of Medicine in South Eastern Nigeria. The study adopted a survey research design with a validated structured questionnaire. A total of 34 lecturers (8 females and 24 males) participated in the study. Results: Thirty one (91.2%) of our respondents has heard of edutainment. Their major source of information was from the internet (n=19; 61.3%) followed by conferences (n=9; 29%). Our respondents showed a positive attitude to edutainment. 28 (82.4%) of our respondents said edutainment is not part of their curriculum and 24 (70.6%) of our respondents use edutainment to teach anatomy. Conclusion: Edutainment in anatomy teaching is necessary and will be productive, there is need to complement traditional teaching method (lectures) with edutainment in anatomy teaching in other to increase students’ interest and understanding.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"379 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123448763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tetrapleura tetraptera and Xylopia aethiopica Consumption Fluctuate Estrogen Levels","authors":"Jimmy Etukudo Okon, Bassey Grace Edet, Nwachukwu Favour Obed, Amagwu, Patrick Iberi","doi":"10.36348/sijap.2023.v06i06.002","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i06.002","url":null,"abstract":"Extract of Tetrapleura tetraptera and Xylopia aethiopica have been used in the management and treatment of various ailments. This study investigated and compared the effects of ethanolic extract of both plants on estrogen in female wistar rats. Twenty-four rats were randomly divided into eight groups (n=3): one group for control and groups 2-8 served as experimental test groups. At the end of twenty-five days of oral administration of Tetrapleura tetraptera and Xylopia aethiopica extract, the test rats were sacrificed under chloroform anaesthesia and estrogen was measured using enzyme-linked immunosorbent assay (ELISA) method. Results showed significant reduction in serum estrogen after administration of low dose of Tetrapleura tetraptera in Group 2 rats at P < 0.05, but a non-significant increase and decrease in serum estrogen level in Groups 3 and 4 respectively at P < 0.05. Xylopia aethiopica extract caused a non- significant decrease in serum Estrogen level in Groups 5 and 6, but a non-significant increase in estrogen level of Group 7 at P < 0.05. In contrast, serum estrogen was significantly increased in Group 8 rats at P < 0.05 when Tetrapleura tetraptera and Xylopia aethiopica extracts were administered simultaneously. In conclusion, results obtained in this study suggest that individually, both Tetrapleura tetraptera and Xylopia aethiopica can affect the secretion and concentration of estrogen. The combination of extract of both plants could exert a positive effect on female fertility by increasing the levels of Estrogen.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132067517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low Dose Earth Ball (Icacina mannii) may be Beneficial to Reproductive Health in Males","authors":"Udokang Nsikak Ephraim, Bassey Grace Edet","doi":"10.36348/sijap.2023.v06i06.001","DOIUrl":"https://doi.org/10.36348/sijap.2023.v06i06.001","url":null,"abstract":"This study investigated the effects of ethanolic extract of Earth ball (Icacina mannii) tuber on the testes. Icacina mannii is a well-known plant in Africa due to its unique ball-shaped underground tuber. The extract was prepared by washing the tuber, cutting it into pieces, sun drying it, and extracting it with 80% ethanol. Four-week-old male Wistar rats were used in the experiment and were randomly assigned to four groups. Group A served as the control and received distilled water, while groups B, C, and D received low, intermediate, and high doses of the extract, respectively. The rats were fed for 28 days. On the twenty-eighth day, the animals' final weight was taken, and blood samples were obtained by cardiac puncture for testosterone level analysis. The testes were recovered for histology. The results showed a significant increase in testosterone level in the low and medium dose groups and a significant decrease in the high dose group when compared with the control. The histologic section of the testes of rats in groups B and C revealed hypochromic sections of seminiferous tubules with swollen germinal cells and spermatogenic lining cells and irregular alignment of myoid cells when compared to the control group. The testicular histologic section of rats in group D showed atrophied and necrotic testicular cells. This study shows that Icacina mannii tuber could be a potential plant for research in the management of infertility in men due to testosterone deficiency, but high doses could be necrotic and atrophic to the testes.","PeriodicalId":317608,"journal":{"name":"Scholars International Journal of Anatomy and Physiology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131484009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}