European Polymer Journal最新文献_第10页

Organosilicone-based clustered phosphinic acid endows outstanding synergistic flame retardancy of epoxy resins

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-26 DOI: 10.1016/j.eurpolymj.2025.113771

Yize Wang , Lijie Qu , Lijun Qian , Wang Xi , Jingyu Wang , Yong Qiu

{"title":"Organosilicone-based clustered phosphinic acid endows outstanding synergistic flame retardancy of epoxy resins","authors":"Yize Wang , Lijie Qu , Lijun Qian , Wang Xi , Jingyu Wang , Yong Qiu","doi":"10.1016/j.eurpolymj.2025.113771","DOIUrl":"10.1016/j.eurpolymj.2025.113771","url":null,"abstract":"<div><div>In this study, an organosilicone-based clustered phosphinic acid (MVCP) was successfully synthesized by an addition reaction with 2,4,6,8-tetra-methyl-2,4,6,8-tetra-vinyl-<em>cyclo</em>-tetrasiloxane (MVC) and hypophosphorous acid (HPA). MVCP was applied to biscitraconimide-reinforced epoxy resin (BCIEP) systems separately or along with TAD, a 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) derivative flame retardant. MVCP/TAD modified BCIEP were investigated systematically concerning on the flame retardancy and mechanism. When the flame retardants containing reached 3 wt%, the limiting oxygen index (LOI) of 3(MVCP/TAD)/BCIEP was increased to 31.2%, while UL 94 reached V-0 level. The peak heat release rate (pk-HRR) of 3(MVCP/TAD)/BCIEP was reduced by 37.3% and the charring residual rate was increased by 7.3% in the cone calorimetry test results, compared to those of BCIEP. Upon combustion, the clustered MVCP formed an aerogel-like residual carbon structure on the surface of the blends through the characteristics of its own silica aggregation, indicating that MVCP was an excellent condensed phase flame retardant. Meanwhile, MVCP reduced the damage of TAD to the mechanical properties of the matrix, showing a broad application prospect.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"227 ","pages":"Article 113771"},"PeriodicalIF":5.8,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143177459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

H2O2-responsive mPEG-2-mercapto-1-methylimidazole prodrug nanosystem for enhanced therapeutic efficacy against hyperthyroidism

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-25 DOI: 10.1016/j.eurpolymj.2025.113767

Yue Dai , Dian Zheng , Yanan Zhao , Wenying Wei , Xiaopei Wu , Honglian Dai

{"title":"H2O2-responsive mPEG-2-mercapto-1-methylimidazole prodrug nanosystem for enhanced therapeutic efficacy against hyperthyroidism","authors":"Yue Dai , Dian Zheng , Yanan Zhao , Wenying Wei , Xiaopei Wu , Honglian Dai","doi":"10.1016/j.eurpolymj.2025.113767","DOIUrl":"10.1016/j.eurpolymj.2025.113767","url":null,"abstract":"<div><div>Methimazole (MMI) is a widely used anti-hyperthyroidism drug. To improve the therapeutic effect of MMI and reduce its side effects on thyroid and liver, a new hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) responsive prodrug nanosystem for the therapy of hyperthyroidism was constructed via thiol-Michael addition between MMI and propiolic acid and followed by esterification with polyethylene glycol monomethyl ether (mPEG) and then ultrasonic dispersion. The α, β-unsaturated C = C double bond (−SCH = CHCOO–) in the prodrug could be cleaved by high concentrations of H<sub>2</sub>O<sub>2</sub> (0.3 mM or above) to release MMI, which was verified by <sup>1</sup>H nuclear magnetic resonance (<sup>1</sup>H NMR) and electrospray ionization mass spectrometry (ESI MS). Esterase and weakly acidic pH stimulation could also enhance the drug release. The cell experiment demonstrated that the nanoparticles (NPs) could significantly elevate diseased cell-selective drug release and the released amount could be adjusted according to the level of H<sub>2</sub>O<sub>2</sub> in the diseased cells. In addition, due to the synergy of H<sub>2</sub>O<sub>2</sub>-stimulated drug release and H<sub>2</sub>O<sub>2</sub>-deprivation, the NPs showed a more noticeable inhibition effect on lactoperoxidase (LPO) and were more effective in hyperthyroidism treatment than MMI. More importantly, in vitro cell culture studies and in vivo evaluations demonstrated that the system had markedly reduced thyroid toxicity and hepatotoxicity compared with MMI. It also possessed a prolonged circulating half-life, and could significantly reduce the oxidative damage of thyroid and liver tissues caused by hyperthyroidism. Thus, this nanosystem provides a novel strategy for improving the therapeutic efficacy of MMI against hyperthyroidism.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"228 ","pages":"Article 113767"},"PeriodicalIF":5.8,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Waste tire based thermoreversible elastomeric networks

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-25 DOI: 10.1016/j.eurpolymj.2025.113770

Boumekla Yougourthen , Chataigner Isabelle , Dez Isabelle

引用次数: 0

Glutathione-integrated waterborne polyurethanes: aqueous dispersible, redox-responsive biomaterials for cancer drug delivery

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-23 DOI: 10.1016/j.eurpolymj.2025.113759

Francesco Cancilla , Annalisa Martorana , Calogero Fiorica , Giovanna Pitarresi , Gaetano Giammona , Fabio S. Palumbo

{"title":"Glutathione-integrated waterborne polyurethanes: aqueous dispersible, redox-responsive biomaterials for cancer drug delivery","authors":"Francesco Cancilla , Annalisa Martorana , Calogero Fiorica , Giovanna Pitarresi , Gaetano Giammona , Fabio S. Palumbo","doi":"10.1016/j.eurpolymj.2025.113759","DOIUrl":"10.1016/j.eurpolymj.2025.113759","url":null,"abstract":"<div><div>Waterborne polyurethanes (WPUs) are increasingly recognized for their eco-friendly characteristics and mechanical versatility, offering a sustainable alternative to solvent-based polyurethanes. In this study, redox-responsive glutathione-extended WPUs were developed to enable targeted drug release in the reductive tumour microenvironment. Three WPUs with increasing hydrophilic character were synthesized using a PCL-PEG-PCL triblock copolymer, isophorone diisocyanate and 2,2-bis(hydroxymethyl)propionic acid (DMPA) as an emulsifier, allowing efficient water dispersion of hydrophobic polyurethane segments. A purification process was developed to replace triethylammonium counterions with sodium ions, resulting in a dried polymer easily redispersible in water through autoclaving. Membranes produced from WPU dispersions demonstrated excellent hydrolytic stability and high hydrophilicity. Effective paclitaxel (PTX) loading (40 μg/mg) was achieved during autoclaving and controlled drug release was observed, with increased release rates under reductive conditions. Under homeostatic conditions, less than 20 % of the loaded PTX was released over 16 days, while in a reductive tumour-like environment, the release rate increased to 40 %, indicating strong redox responsiveness. Enhanced cytotoxicity was also observed in HCT-116 cells under simulated reductive conditions. This redox-triggered drug release, responsive to high glutathione levels of tumours, highlights the potential of WPUs for localized cancer therapies. These biomaterials offer a promising platform for developing injectable or implantable WPU-based systems for peritumoral or intratumoral delivery of anticancer drugs, reducing off-target effects and improving treatment efficacy.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"226 ","pages":"Article 113759"},"PeriodicalIF":5.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photopolymerization initiated by aggregation-induced emission (AIE) dyes: Towards design of fluorescent photocatalysts with hybridized excited state

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-22 DOI: 10.1016/j.eurpolymj.2025.113750

Ke Sun , Wenlong Tang , Mingyang Wu , Yuchen Yang , Yizhi Shao , Tao Gong , Yangyang Xu , Hongwei Ma , Jianyong Jin

{"title":"Photopolymerization initiated by aggregation-induced emission (AIE) dyes: Towards design of fluorescent photocatalysts with hybridized excited state","authors":"Ke Sun , Wenlong Tang , Mingyang Wu , Yuchen Yang , Yizhi Shao , Tao Gong , Yangyang Xu , Hongwei Ma , Jianyong Jin","doi":"10.1016/j.eurpolymj.2025.113750","DOIUrl":"10.1016/j.eurpolymj.2025.113750","url":null,"abstract":"<div><div>Despite the truth that organic chromophores were deeply investigated as light-harvesting photocatalysts (PCs) or photoinitiators (PIs), innovative designs on the photoredox catalysts with specific photophysical/chemical characteristics, for instance, chromophores with clear hybridized excited state or aggregation-induced emission (AIE) are rarely reported to conduct visible-light induced polymerization. Here, we newly designed four chromophores as PCs in photopolymerization, with Donor-Acceptor structure and hybrid local and charge-transfer (HLCT) states, in order to provide diradicals with moderate concentrations while inducing the photopolymerization of acrylate monomers under separate light sources with different wavelengths. As results, moderate spin–orbit coupling (SOC) coefficients may assist to depress the retardation or inhibition of photopolymerization processes, which enables to efficiently induce free radical photopolymerization of acrylate monomer upon light irradiation. What’s more, two of them are recognized as typical AIE dyes, direct laser write experiments were thus performed on AIE dye-induced photopolymerization, especially for the water-soluble resin, poly(ethylene glycol) diacrylate (PEGDA), which seems to expand their applications in bio and medical fields as perspective.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"226 ","pages":"Article 113750"},"PeriodicalIF":5.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and photovoltaic properties of the efficient polymer donor based on benzo[1,2-b:4,5-b’]difuran unit

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-22 DOI: 10.1016/j.eurpolymj.2025.113766

Jin Luo, Lei Wang, Linglong Ye, Songting Tan

{"title":"Synthesis and photovoltaic properties of the efficient polymer donor based on benzo[1,2-b:4,5-b’]difuran unit","authors":"Jin Luo, Lei Wang, Linglong Ye, Songting Tan","doi":"10.1016/j.eurpolymj.2025.113766","DOIUrl":"10.1016/j.eurpolymj.2025.113766","url":null,"abstract":"<div><div>Benzo[1,2-<em>b</em>:4,5-<em>b</em>’]dithiophene (BDT) has been used as the electron-donating block in the majority of polymer donors which generally achieve high-performance organic solar cells (OSCs). Benzo[1,2-<em>b</em>:4,5-<em>b</em>’]difuran (BDF), with a similar structure to BDT, has attracted increasing attention because its raw materials are renewable. To diversify building blocks for high-performance donor polymers, we synthesized a new polymer donor, namely PFD, based on the BDF and benzo[1,2-<em>c</em>:4,5-<em>c’</em>]dithiophene-4,8-dione (BDD) units as the backbone with 1-(2-butyloctyl)-chlorobenzene as the side-chain. The PFD possesses a deeper highest occupied molecular orbital (HOMO) energy level of −5.54 eV, which helps to generate a high open-circuit voltage (<em>V</em><sub>oc</sub>) in OSCs. When Y6 was chosen as an acceptor, a fair <em>V</em><sub>oc</sub> of 0.867 V and a decent PCE of 16.95 % were achieved in the binary OSCs. With the addition of a small molecule acceptor BTMe-4Cl as the third component, the PCE of the PFD:Y6:BTMe-4Cl ternary device has improved to 17.58 %. The results indicate that BDF-based polymers exhibit the potential for fabricating efficient OSCs.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"226 ","pages":"Article 113766"},"PeriodicalIF":5.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simple and efficient synthesis and functionalization of well-defined, linear telechelic polycarbonates by reversible polycondensation through alkoxide exchange reaction

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-22 DOI: 10.1016/j.eurpolymj.2025.113762

Takayoshi Katoh, Nao Kobayashi, Yoshihiro Ohta, Tsutomu Yokozawa

{"title":"Simple and efficient synthesis and functionalization of well-defined, linear telechelic polycarbonates by reversible polycondensation through alkoxide exchange reaction","authors":"Takayoshi Katoh, Nao Kobayashi, Yoshihiro Ohta, Tsutomu Yokozawa","doi":"10.1016/j.eurpolymj.2025.113762","DOIUrl":"10.1016/j.eurpolymj.2025.113762","url":null,"abstract":"<div><div>We investigated the synthesis of telechelic polycarbonates free from cyclic polymers by means of reversible polycondensation of diol formate <strong>1</strong> and dipropyl carbonate (<strong>2</strong>) under reduced pressure, using an excess of either reagent in the presence of 5 mol% potassium <em>tert</em>-butoxide (<em><sup>t</sup></em>BuOK) as an alkoxide exchange catalyst. In the polycondensation of dodecane-1,12-diol diformate (<strong>1a</strong>) with excess <strong>2</strong> in diglyme, linear polycarbonates with a propyl carbonate moiety at both ends were obtained free from cyclic polymer. The <em>M</em><sub>n</sub> value of the obtained polymer was increased to 6510 when the amount of <strong>2</strong> was decreased to 1.10 equivalents, while the propyl carbonate ends remained. However, the polycondensation using 1.05 equivalents of <strong>2</strong> afforded polycarbonate with a hydroxyl end and cyclic polymer, although the molecular weight was higher than 13000. This result can be explained in terms of the evaporation of <strong>2</strong>, which has a low boiling point, during the polymerization under reduced pressure. On the other hand, the polycondensation of excess <strong>1a</strong> with <strong>2</strong> in bulk yielded linear polycarbonates with a hydroxyl group at both ends. The <em>M</em><sub>n</sub> value increased to 10,100 as the amount of <strong>1a</strong> was decreased to 1.04 equivalents, while the hydroxyl ends remained. Furthermore, the polycondensation of equimolar <strong>1a</strong> with <strong>2</strong> in the presence of functional carbonate <strong>3</strong> or functional diol ester <strong>4</strong> afforded telechelic polycarbonates with functional groups derived from <strong>3</strong> or <strong>4</strong> at both ends.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"227 ","pages":"Article 113762"},"PeriodicalIF":5.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143177462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced wound-healing by hydrogel from okra mucilage grafted with Poly-2-Acrylamido-2-methylpropane sulfonic acid (AMPS), a stimuli-responsive polymer

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-22 DOI: 10.1016/j.eurpolymj.2025.113748

Vandna Choudhary, Amita Malik

{"title":"Enhanced wound-healing by hydrogel from okra mucilage grafted with Poly-2-Acrylamido-2-methylpropane sulfonic acid (AMPS), a stimuli-responsive polymer","authors":"Vandna Choudhary, Amita Malik","doi":"10.1016/j.eurpolymj.2025.113748","DOIUrl":"10.1016/j.eurpolymj.2025.113748","url":null,"abstract":"<div><div>Mucilage, a naturally occurring polymer found in plants, has applications in water filtration, drug delivery, and the food industry. This study aimed to enhance the bioavailability of wound healing medications by modifying okra mucilage with the hydrophilic monomer 2-Acrylamido-2-methylpropane sulfonic acid (AMPS) through free radical polymerization. Various ratios of okra mucilage to AMPS, with ethylene glycol dimethacrylate as a cross-linker and potassium persulfate as an initiator, were tested. The resulting hybrid polymers exhibited biocompatibility and stimuli-responsive behavior at different pH levels. Swelling studies in physiological fluids revealed that the 1:10 okra to AMPS ratio demonstrated the best swelling behavior, which was selected for further in vitro and in vivo evaluations. Thermal analysis, X-ray diffraction (XRD), Scanning Electron Microscope (SEM), and Fourier Transform Infrared Spectroscopy (FT-IR) confirmed the successful polymer modification. At pH 4, the 1:10 cross-linker ratio achieved maximum swelling of 194%. The polymer exhibited 40% drug loading and 77.2% encapsulation efficiency with Calendula officinalis flower extract (CE). In vivo tests showed significant improvements in wound contraction, wound index, and epithelization time. The wound closure in the encapsulated sample was 97.15%, compared to 86.7% in the control. These results suggest that the pH-responsive okra-AMPS polymer system offers a promising controlled-release solution for wound healing.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"227 ","pages":"Article 113748"},"PeriodicalIF":5.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143178451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bactericidal and anti-adhesion polymers containing trialkyl-(4-vinylbenzyl)ammonium and plant-based tocopherol for coating applications

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-21 DOI: 10.1016/j.eurpolymj.2025.113746

Yeonsu Cho, Hyo Kang

{"title":"Bactericidal and anti-adhesion polymers containing trialkyl-(4-vinylbenzyl)ammonium and plant-based tocopherol for coating applications","authors":"Yeonsu Cho, Hyo Kang","doi":"10.1016/j.eurpolymj.2025.113746","DOIUrl":"10.1016/j.eurpolymj.2025.113746","url":null,"abstract":"<div><div>Polymers containing trialkyl-(4-vinylbenzyl)ammonium and plant-based tocopherol (abbreviated as P(C8N<sub>10</sub>TOC<sub>#</sub>), #=10, 30, 50, 70, and 90), where # indicates the molar content (%) of the tocopherol moiety in the side group, were prepared using the poly(4-chloromethylstyrene) (PCMS) as precursor and the trioctylamine and tocopherol as substituent to evaluate its abilities for coating application. Transparent P(C8N<sub>10</sub>TOC<sub>#</sub>) films were prepared on a glass substrate by spin coating and polymer films showed bactericidal and anti-adhesive properties with different alkyl chain lengths of ammonium and contents of tocopherol as substitution. It was found that the P(C8N<sub>10</sub>TOC<sub>#</sub>)s have a probability of bactericidal function and possess bactericidal properties above 49.6 and 94.6 % against <em>Escherichia coli</em> (<em>E. coli</em>; ATCC 8739) and <em>Staphylococcus aureus</em> (<em>S. aureus</em>; ATCC 6538), respectively. The anti-adhesive properties of the P(C8N<sub>10</sub>TOC<sub>90</sub>) films were shown against various contaminations with low surface energy. In detail, P(C8N<sub>10</sub>TOC<sub>#</sub>) films were expected to exhibit dual functional properties because they contained an optimum amount of hydrophilic trioctylammonium units and a sufficient amount of hydrophobic plant-based tocopherol units to impart bactericidal activity and low surface energy, respectively. Furthermore, the thermal, optical, and surface properties of the P(C8N<sub>10</sub>TOC<sub>#</sub>) films were investigated. Thus, this study reveals the potential of the P(C8N<sub>10</sub>TOC<sub>#</sub>) coating as a coating agent in various application areas and is also the first study to investigate the bifunctional properties of polymers containing quaternary ammonium and plant-based tocopherol moieties.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"226 ","pages":"Article 113746"},"PeriodicalIF":5.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143093350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of solvophilic monomer unit distribution on the block copolymers in RAFT-mediated dispersion polymerization-induced self-assembly

IF 5.8 2区化学

European Polymer Journal Pub Date : 2025-01-21 DOI: 10.1016/j.eurpolymj.2025.113760

Ling Li , Yifan Wang , Yong Wu

{"title":"Effect of solvophilic monomer unit distribution on the block copolymers in RAFT-mediated dispersion polymerization-induced self-assembly","authors":"Ling Li , Yifan Wang , Yong Wu","doi":"10.1016/j.eurpolymj.2025.113760","DOIUrl":"10.1016/j.eurpolymj.2025.113760","url":null,"abstract":"<div><div>Previous studies showed the crucial effects of morphology and size of polymer vesicles on applications. Herein, we report an efficient approach for producing amphiphilic block copolymer (BCP) vesicles with various sizes via tunable distributions of solvophilic monomer units of acrylic acid (AA) on the amphiphilic BCP in reversible addition-fragmentation chain transfer (RAFT)-mediated dispersion polymerization-induced self-assembly. The distribution of solvophilic block was facilely regulated by RAFT agents with two structures and copolymerized with solvophobic monomer (styrene, St). Transmission electron microscopy and dynamic light scattering were utilized for the characterization of the morphology and size of self-assemblies. As a consequence, PAA-<em>b</em>-PSt-<em>b</em>-PSt vesicles with sizes ranging from 85 ± 8 nm to 692 ± 59 nm were produced through the distribution of BCP. In addition, large compound vesicles, porous nanospheres, and multilamellar vesicles were observed in the system. Besides, we also combined the experiments with theoretical calculations to demonstrate the effect of different AA distributions in the block copolymer chains on assembly behavior, providing a new strategy for the efficient preparation of polymer nanoparticles.</div></div>","PeriodicalId":315,"journal":{"name":"European Polymer Journal","volume":"226 ","pages":"Article 113760"},"PeriodicalIF":5.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143128428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0