{"title":"Introduction to Human Nutrition, edited by Michael J Gibney, Hester H Vorster, and Frans J Kok, 2002, 342 pages, paperback, $49.99. Blackwell Science Ltd, Oxford, United Kingdom.","authors":"J. Gilchrist","doi":"10.1093/AJCN/78.6.1228","DOIUrl":"https://doi.org/10.1093/AJCN/78.6.1228","url":null,"abstract":"","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125211607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to B Sreedhar","authors":"T. Lind, L. Persson, B. Lönnerdal","doi":"10.1093/AJCN/78.6.1226","DOIUrl":"https://doi.org/10.1093/AJCN/78.6.1226","url":null,"abstract":"","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"264 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124987123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to RP Heaney","authors":"R. Wood, L. Martini","doi":"10.1093/AJCN/78.3.493A","DOIUrl":"https://doi.org/10.1093/AJCN/78.3.493A","url":null,"abstract":"","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114501147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serum 25-hydroxyvitamin D response to oral vitamin D intake in children.","authors":"A. Zittermann","doi":"10.1093/AJCN/78.3.496A","DOIUrl":"https://doi.org/10.1093/AJCN/78.3.496A","url":null,"abstract":"","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"118593385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Nutrition Transition: Diet and Disease in the Developing World edited by Benjamin Caballero and Barry M Popkin, 2002, 276 pages, hardcover, $79.95. Academic Press, London.","authors":"N. Solomons, C. Nieves","doi":"10.1093/AJCN/78.3.500","DOIUrl":"https://doi.org/10.1093/AJCN/78.3.500","url":null,"abstract":"","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117913257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in Nutritional Research, Vol 10, Immunological Properties of Milk, edited by Bill Woodward and Harold H Draper, 2001, 410 pages, hardcover, $140. Kluwer Academic/Plenum Publishers, New York.","authors":"W. Heird","doi":"10.1093/AJCN/77.3.755","DOIUrl":"https://doi.org/10.1093/AJCN/77.3.755","url":null,"abstract":"Make more knowledge even in less time every day. You may not always spend your time and money to go abroad and get the experience and knowledge by yourself. Reading is a good alternative to do in getting this desirable knowledge and experience. You may gain many things from experiencing directly, but of course it will spend much money. So here, by reading advances in nutritional research vol 10 immunological properties of milk, you can take more advantages with limited budget.","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"118706636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to R Cooper and A Luke","authors":"N. Schonfeld-Warden, C. Warden","doi":"10.1093/AJCN/77.3.752","DOIUrl":"https://doi.org/10.1093/AJCN/77.3.752","url":null,"abstract":"","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117573246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advances in Nutritional Research, Vol 10, Immunological Properties of Milk","authors":"W. Heird","doi":"10.1093/AJCN/77.3.755B","DOIUrl":"https://doi.org/10.1093/AJCN/77.3.755B","url":null,"abstract":"","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122425663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence.","authors":"D. Mischoulon, M. Fava","doi":"10.1093/AJCN/76.5.1158S","DOIUrl":"https://doi.org/10.1093/AJCN/76.5.1158S","url":null,"abstract":"Major depression remains difficult to treat, despite the wide array of registered antidepressants available. In recent years there has been a surge in the popularity of natural or alternative medications. Despite this growing popularity, there is limited evidence for the effectiveness of many of these natural treatments. S-adenosyl-L-methionine (SAMe) is one of the better studied of the natural remedies. SAMe is a methyl donor and is involved in the synthesis of various neurotransmitters in the brain. Derived from the amino acid L-methionine through a metabolic pathway called the one-carbon cycle, SAMe has been postulated to have antidepressant properties. A small number of clinical trials with parenteral or oral SAMe have shown that, at doses of 200-1600 mg/d, SAMe is superior to placebo and is as effective as tricyclic antidepressants in alleviating depression, although some individuals may require higher doses. SAMe may have a faster onset of action than do conventional antidepressants and may potentiate the effect of tricyclic antidepressants. SAMe may also protect against the deleterious effects of Alzheimer disease. SAMe is well tolerated and relatively free of adverse effects, although some cases of mania have been reported in bipolar patients. Overall, SAMe appears to be safe and effective in the treatment of depression, but more research is needed to determine optimal doses. Head-to-head comparisons with newer antidepressants should help to clarify SAMe's place in the psychopharmacologic armamentarium.","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124578074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Saletu, P. Anderer, C. Padova, A. Assandri, G. Saletu-Zyhlarz
{"title":"Electrophysiological neuroimaging of the central effects of S-adenosyl-l-methionine by mapping of electroencephalograms and event-related potentials and low-resolution brain electromagnetic tomography","authors":"B. Saletu, P. Anderer, C. Padova, A. Assandri, G. Saletu-Zyhlarz","doi":"10.1093/AJCN/76/5.1162S","DOIUrl":"https://doi.org/10.1093/AJCN/76/5.1162S","url":null,"abstract":"Background: S-Adenosyl-L-methionine (SAMe, or ademetionine) is a naturally occurring molecule used as both a nutraceutical and a pharmaceutical to treat depression. Objective: The central mode of action of SAMe was investigated in 20 healthy volunteers by mapping of electroencephalograms (EEGs) and event-related potentials (ERPs) and low-resolution brain electromagnetic tomography (LORETA). Design: In an acute and subacute, double-blind, placebo-controlled, crossover study, subjects received in random order infusions of 800 mg SAMe and placebo for 7 d, with a washout period of 3 wk between the 2 treatment periods. EEG recordings were made 0, 1, 3, and 6 h after and ERP recordings were made 0 and I h after the drug infusions on days 1 and 7. Results: Multivariate analyses of variance and Hotelling T 2 tests showed significant acute and subacute encephalotropic effects of SAMe compared with placebo. Acute pharmaco-EEG changes were typical of classic antidepressants of the thymoleptic type; subacute alterations were typical of congnition enhancers. Regarding ERPs, standard N I and P2 latencies were shortened, and target P300 latencies were lengthened. Nl amplitudes increased after subacute treatment, and temporooccipital P300 amplitudes increased after the acute dose Similar changes were described for antidepressants. LORETA showed that the N2 source strength increased in both the left and the right temporal lobes, whereas the P300 source strength increased in the dorsolateral prefrontal regions and decreased in the ventral limbic regions Conclusion: EEG-ERP mapping identified SAMe as an antidepressant. LORETA targeted brain regions crucial in the therapeutic efficacy of antidepressants.","PeriodicalId":315016,"journal":{"name":"The American journal of clinical nutrition","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127245779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}