Medical Express最新文献_第7页

Appropriate adherence to antiretroviral therapy in the Alto Paranaiba, Minas Gerais, Brazil 在巴西米纳斯吉拉斯州的上巴拉奈巴，适当坚持抗逆转录病毒治疗

Medical Express Pub Date : 2016-08-04 DOI: 10.5935/MEDICALEXPRESS.2016.03.05

G. Souza, A. Tiburcio, M. Koike

{"title":"Appropriate adherence to antiretroviral therapy in the Alto Paranaiba, Minas Gerais, Brazil","authors":"G. Souza, A. Tiburcio, M. Koike","doi":"10.5935/MEDICALEXPRESS.2016.03.05","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.03.05","url":null,"abstract":"OBJECTIVE: This study aimed to assess the adherence to antiretroviral treatment of HIV-infected patients at the Centro de Referencia Viva Vida in Patos de Minas, Minas Gerais, Brazil. METHODS: As a descriptive and quantitative retrospective cross-sectional study, we enlisted HIV-infected patients, over 18 years old, users of highly active antiretroviral therapy (HAART) from June 2011 to July 2012. Data on withdrawal of medication and viral load were collected from the drug logistics management information system and from the medical records, respectively. Sociodemographic and data regarding HAART use were collected manually, using appropriate forms. The CEAT-HIV questionnaire was filled out by140 patients who were using HAART. For data analysis, we used ANOVA and Kruskal-Wallis Rank Sum tests, complemented with Dunn's test, when necessary. P < 0.05 was adopted as the limit for significance. RESULTS: The age group 18-30 years presented lower adherence compared with the group aged over 60 years (p = 0.047). Regarding the HAART usage time, there was no difference between groups (p = 0.515). For the number of pills taken per day, there was greater adherence for patients taking up to 4 pills compared to those taking 5-10 pills daily (p = 0.037). Concerning adherence measured by the CEAT-HIV questionnaire, there was strict/rigorous adherence in 57.8% of patients, with 21.4% of the patients classified as having adequate adherence, according to the data on dispensation of medicines. CONCLUSION: Patients participating in HAART and taking up to 4 pills had good adherence to treatment.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Is there a link between upper gastrointestinal polyps and colonic polyps? A retrospective study from a Turkish cohort 上消化道息肉和结肠息肉之间有联系吗?来自土耳其队列的回顾性研究

Medical Express Pub Date : 2016-07-23 DOI: 10.5935/MEDICALEXPRESS.2016.04.06

Meral Sözen, M. Yalaza, C. Turkay

{"title":"Is there a link between upper gastrointestinal polyps and colonic polyps? A retrospective study from a Turkish cohort","authors":"Meral Sözen, M. Yalaza, C. Turkay","doi":"10.5935/MEDICALEXPRESS.2016.04.06","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.04.06","url":null,"abstract":"OBJECTIVE: To investigate the incidence and associated demographical and clinical factors related to lower GI polyps and neoplasms in patients with upper GI polyps and neoplasms. METHODS: We investigated 99 patients who had upper GI polyps and neoplasms and who were screened with colonoscopy: the following data were collected: demographical and clinical data consisting of age, sex, smoking status, presence of H. pylori infection, placement of upper GI polyps or neoplasms, presence of gastric atrophy, usage of proton pump inhibitors (PPI), presence of lower GI polyp or neoplasm, type of colon polyp, pathological grade of colon polyp. The patients were grouped according to having/not having lower GI polyps and neoplasms; data was compared between groups. RESULTS: Smoking rate was significantly higher in patients with lower GI polyps and neoplasms (χ2: 4.35, p: 0.03). Furthermore, there was a signifant association between presence of lower GI polyps and neoplasms vs. smoking (OR: 2.44 CI: 1.01-5.84, p: 0.04). CONCLUSIONS: Patients with upper GI polyps and neoplasms who are smokers should be considered as candidates for having lower GI polyps and neoplasms and should be screened and followed more carefully. Additionally, we believe that large sampled and prospective studies are needed to higligt the association between upper GI polyps and presence of lower GI polyps and neoplasms.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"3 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2016-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings 精神分裂症的认知行为疗法:疗效、最新趋势和神经生物学发现综述

Medical Express Pub Date : 2016-07-17 DOI: 10.5935/MEDICALEXPRESS.2016.05.01

Maristela Candida, Carlos Campos, Carlos Campos, Bárbara Monteiro, N. Rocha, F. Paes, A. Nardi, S. Machado

{"title":"Cognitive-behavioral therapy for schizophrenia: an overview on efficacy, recent trends and neurobiological findings","authors":"Maristela Candida, Carlos Campos, Carlos Campos, Bárbara Monteiro, N. Rocha, F. Paes, A. Nardi, S. Machado","doi":"10.5935/MEDICALEXPRESS.2016.05.01","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.05.01","url":null,"abstract":"INTRODUCAO: A terapia cognitivo-comportamental (TCC) tem sido recomendada em diversas guidelines internacionais como a intervencao psicoterapeutica padrao de ouro para pacientes com esquizofrenia. Esta revisao tem como objetivo fornecer uma visao global sobre os avancos recentes da TCC na esquizofrenia. METODOS: Para esta revisao narrativa foi realizada uma busca eletronica na PubMed/MEDLINE, Web of Science e Cochrane Database utilizando as palavras-chave: \"schizophrenia\", \"psychosis\", \"cognitive-behavioral therapy\", \"CBT\" e \"psychotherapy\". RESULTADOS: Varias revisoes sistematicas suportam a eficacia da TCC na reducao a curto e longo prazo dos sintomas positivos e negativos da esquizofrenia. Na ultima decada, a TCC tem sido aplicada a individuos com alto risco de psicose, sendo tambem exploradas abordagens inovadoras na sua utilizacao (curta duracao, web-based, autogestao). Redes neurais responsaveis por funcoes cognitivas de nivel superior tem sido associadas a respostas positivas apos TCC para esquizofrenia. Existe ainda evidencia preliminar que a TCC promove a ativacao de zonas pre-frontais responsaveis pela modulacao top-down face a ameacas sociais. CONCLUSAO: Na ultima decada, a TCC para esquizofrenia tem explorado novos desfechos, intervindo em populacoes agudas e pre-clinicas e utilizado metodos alternativos para alcancar mais pacientes e reduzir custos O perfil neurocognitivo dos pacientes aparenta ter um papel critico na resposta ao tratamento, pelo que combinar a TCC com reabilitacao cognitiva podera potenciar os seus efeitos terapeuticos. Apesar da TCC ser uma pratica recomendada para a esquizofrenia, estudos futuros usando protocolos inovadores e explorando preditores e desfechos relacionados com o cerebro poderao possibilitar que esta intervencao seja mais eficaz, personalizavel e alcance o maximo numero de pacientes possivel.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"25 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Anthropometric Risk Factors for Metabolic Syndrome in HIV patients HIV患者代谢综合征的人体测量危险因素

Medical Express Pub Date : 2016-06-25 DOI: 10.5935/MEDICALEXPRESS.2016.04.05

J. A. Leal, M. A. Fausto, M. Carneiro

{"title":"Anthropometric Risk Factors for Metabolic Syndrome in HIV patients","authors":"J. A. Leal, M. A. Fausto, M. Carneiro","doi":"10.5935/MEDICALEXPRESS.2016.04.05","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.04.05","url":null,"abstract":"OBJECTIVE: Metabolic syndrome, which affects the general population in epidemic proportions, is associated with a set of cardiovascular disease risk factors. The aims of this cross-sectional study were to determine the prevalence and investigate the risk factors associated with metabolic syndrome in outpatients living with HIV/AIDS using anthropometric and clinical evaluations. METHOD: The study was carried out on 253 HIV infected outpatients. Metabolic syndrome was classified according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP/ATPIII) and the International Diabetes Federation (IDF) criteria. Logistic regression was used to identify factors associated with the metabolic syndrome. RESULTS: The prevalence of metabolic syndrome varied from 19.4% to 26.4%, according to the criterion used. The factors associated with it in the two classifications used, when adjusted by sex and BMI, were age (≥ 40years) and subscapular skinfold (> 12 mm). In the final model, using the NCEP/ATPIII criterion the risk factors associated with metabolic syndrome were age ≥ 40 years (OR = 3.18; CI95% = 1.42; 7.14) and subscapular skinfold > 12 mm (OR = 2.85, CI95% = 1.13; 7.17). In the final model, using the IDF criterion the risk factors associated with metabolic syndrome were age (OR = 3.38, CI95% = 1.61; 7.10) and subscapular skinfold > 12 mm (OR = 4.37, CI95% = 1.84; 10.39). CONCLUSION: In clinical practice, the regular monitoring of subscapular skinfold can help in the identification of HIV infected individuals in risk of MS.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"3 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2016-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Effects of dual-task interventions on gait performance of patients with Parkinson's Disease: A systematic review 双任务干预对帕金森病患者步态表现的影响:一项系统综述

Medical Express Pub Date : 2016-06-22 DOI: 10.5935/MEDICALEXPRESS.2016.04.01

Luís A. A. Santos, Carlos Campos, Teresa Bento, E. Lattari, A. Nardi, N. Rocha, S. Machado

{"title":"Effects of dual-task interventions on gait performance of patients with Parkinson's Disease: A systematic review","authors":"Luís A. A. Santos, Carlos Campos, Teresa Bento, E. Lattari, A. Nardi, N. Rocha, S. Machado","doi":"10.5935/MEDICALEXPRESS.2016.04.01","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.04.01","url":null,"abstract":"OBJECTIVE: Parkinson's disease is characterized by motor and non-motor symptoms that impair patients' gait performance, especially while performing dual/concurrent tasks. These deficits impair patients' daily function, because dual-tasking is a crucial ability in terms of everyday living. The aim of this study was to systematically review the effects of dual task interventions on gait performance of patients with Parkinson's disease. METHOD: Studies were retrieved from MEDLINE/PubMed, LILACS and SciELO. We used the PICOS strategy to determine eligibility criteria. The search strategy included an advanced search on the included databases, using the following search query: \"Parkinson's Disease\" AND \"Double Task\" OR \"Concurrent Tasks\" OR \"Gait\" AND \"Walk\". Study selection was carried out by two independent researchers and a third one was called when consensus was needed. RESULTS: A total of 188 articles were identified: 169 articles from Medline/PubMed, 10 articles in SciELO, 8 articles in LILACS and 1 item from manual searches. A total of 56 articles were analyzed regarding the eligibility and exclusion criteria based on full text. A final total of 7 studies were included in the systematic review. CONCLUSION: The different types of dual-task interventions reported (dance, sound stimuli, visual and somatosensory) were associated to improvements in several gait performance indicators of Parkinson's disease patients, including gait speed, stride time and length, cadence and step length. External stimuli seem to play a critical role on specific training effects on dual-task gait performance.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"3 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2016-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5935/MEDICALEXPRESS.2016.04.01","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

The contract-relax proprioceptive neuromuscular facilitation (PNF) stretching can affect the dynamic balance in healthy men 收缩-放松本体感觉神经肌肉促进(PNF)拉伸可影响健康男性的动态平衡

Medical Express Pub Date : 2016-06-06 DOI: 10.5935/MEDICALEXPRESS.2016.04.04

A. Ghram, M. Damak, F. Rhibi, P. H. Marchetti

引用次数: 9

Neck circumference can differentiate obese from non-obese individuals 颈围可以区分肥胖者和非肥胖者

Medical Express Pub Date : 2016-05-22 DOI: 10.5935/MEDICALEXPRESS.2016.04.03

Raquel Eduardo Lucas, Ana Laura Ferreira Fonseca, R. Dantas

{"title":"Neck circumference can differentiate obese from non-obese individuals","authors":"Raquel Eduardo Lucas, Ana Laura Ferreira Fonseca, R. Dantas","doi":"10.5935/MEDICALEXPRESS.2016.04.03","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.04.03","url":null,"abstract":"OBJETIVO: A obesidade e um importante problema de saude publica, com crescente prevalencia na populacao. O diagnostico e fundamentado no indice de massa corporal (IMC). No entanto, a circunferencia do pescoco pode ser uma alternativa para diferenciar obesos de nao obesos. METODO: Circunferencia do pescoco foi medida sobre a cartilagem cricoide, usando uma fita graduada, em 50 individuos nao obesos (66% mulheres) e 97 individuos obesos (65% mulheres) diagnosticados pelo IMC. RESULTADOS: A circunferencia do pescoco foi maior em obesos comparados aos nao obesos, e maior nos homens quando comparados as mulheres. Medidas acima de 42 cm para homens e 36 cm para mulheres foram associados a obesidade, com alta sensibilidade (98%) e especificidade (96%). Nas mulheres houve associacao positiva entre os valores da circunferencia do pescoco com o peso e o IMC. Nas pessoas obesas houve correlacao negativa entre idade e IMC. A altura das mulheres obesas foi menor do que a das mulheres nao obesas. CONCLUSOES: A medida da circunferencia do pescoco pode diferenciar pessoas obesas de nao obesas, com alta sensibilidade e especificidade. Ela e maior em obesos que nao obesos, maior em homens do que em mulheres, e e associada com o grau de obesidade.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"4 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2016-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Body image in a representative sample of overweight, obese and normal weight active older women living in the community: associations with body composition, physical fitness and function 生活在社区的超重、肥胖和正常体重活跃老年妇女的代表性样本中的身体形象:与身体组成、身体健康和功能的关系

Medical Express Pub Date : 2016-05-15 DOI: 10.5935/MEDICALEXPRESS.2016.04.02

V. Raso, C. Garber, R. Mancini, S. Matsudo

{"title":"Body image in a representative sample of overweight, obese and normal weight active older women living in the community: associations with body composition, physical fitness and function","authors":"V. Raso, C. Garber, R. Mancini, S. Matsudo","doi":"10.5935/MEDICALEXPRESS.2016.04.02","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.04.02","url":null,"abstract":"OBJECTIVE: To compare and examine relationships between body image (BI), body composition and physical function in overweight and normal weight active older women. METHOD: We measured body mass (BM), body mass index (BMI), waist circumference (WAIST), grip strength (GS), lower limb muscle strength [LLMS], arm curl, balance, step-in-place test (SIPT), usual walk (WALK), fast walking (fastWALK), single chair stand (CHAIRtime) and repeated chair stand (CHAIRreps) in 398 overweight or obese women (67.2 ± 8.5 years; BMI > 27 kg·m2) and 302 women with a BMI < 27 kg·m2 (67.3 ± 8.5 years). Current (CBI) and ideal body image (IBI), and body dissatisfaction (DS; current - ideal) were determined by participant's responses to standardized silhouettes. RESULTS: Multiple regression analyses verified positive (CBI) and negative associations (DS) for balance in obese category. A positive association with WALK and fastWALK was observed for current (normal weight and obesity categories) and IBI (overweight). There were positive associations for SIPT, arm curl and CHAIRreps. CONCLUSION: Physically active older women showed an elevated prevalence of dissatisfaction regardless of BMI which was mediated by age, and associated with worsened physical function; similar associations were seen for current body image.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"3 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2016-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Establishing a quality management system in a fertility center: experience with ISO 9001 在生育中心建立质量管理体系:ISO 9001的经验

Medical Express Pub Date : 2016-05-09 DOI: 10.5935/MEDICALEXPRESS.2016.03.02

Fabiola C. Bento, S. Esteves

{"title":"Establishing a quality management system in a fertility center: experience with ISO 9001","authors":"Fabiola C. Bento, S. Esteves","doi":"10.5935/MEDICALEXPRESS.2016.03.02","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.03.02","url":null,"abstract":"In Fertility Centers, quality should be measured by how well the organization complies with pre-defined requirements, and by how quality policies are implemented and quality objectives achieved. Having a quality management system (QMS) is a mandatory requirement for IVF centers established in most countries with regulatory guidelines, including Brazil. Nevertheless, none of the regulatory directives specify what a QMS must have in detail or how it should be implemented and/or maintained. ISO 9001 is the most important and widespread international requirement for quality management. ISO 9001 standards are generic and applicable to all organizations in any economic sector, including IVF centers. In this review, we discuss how we implemented QMS according to ISO 9001 and what we achieved 5 years later. In brief, with ISO we defined our structure, policies, procedures, processes and resources needed to implement quality management. In addition, we determined the quality orientation of our center and the quality objectives and indicators used to guarantee that a high-quality service is provided. Once measuring progress became part of our daily routine, quantifying and evaluating the organization's success and how much improvement has been achieved was an inevitable result of our well-established QMS. Several lessons were learned throughout our quality journey, but foremost among them was the creation of an internal environment with unity of purpose and direction; this has in fact been the key to achieving the organization's goals.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5935/MEDICALEXPRESS.2016.03.02","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Depression, stress and guilt are linked to the risk of suicide associated to ectopic pregnancy 抑郁、压力和内疚与异位妊娠相关的自杀风险有关

Medical Express Pub Date : 2016-04-22 DOI: 10.5935/MEDICALEXPRESS.2016.03.07

G. Benute, Debora Cristina Nozzella Bordini, T. Juhas, F. R. Cabar, P. P. Pereira, M. C. S. Lúcia, R. Francisco

引用次数: 2