Medical ExpressPub Date : 2016-01-05DOI: 10.5935/MEDICALEXPRESS.2016.03.09
V. Raso, R. Cassilhas, M. Santana, R. Boscolo, V. Viana, V. Grassmann, S. Tufik, M. Mello
{"title":"Predictors of muscle strength in older individuals","authors":"V. Raso, R. Cassilhas, M. Santana, R. Boscolo, V. Viana, V. Grassmann, S. Tufik, M. Mello","doi":"10.5935/MEDICALEXPRESS.2016.03.09","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2016.03.09","url":null,"abstract":"PURPOSE: To analyze possible relationships between load, body mass and lean body mass in an effort to provide norm-referenced standards for the one repetition maximum test and to predict whole body muscle strength (WBMS) in older individuals. METHODS: We measured body mass, lean body mass and the one repetition maximum (1RM) test in different exercises in 189 older men and women aged 61 to 82 years. Whole body muscle strength (WBMS) was calculated as the sum of loads of the different exercises. RESULTS: For women, the inclusion of body mass or lean body mass increased the R2 from 0.41 to 0.82, and yielded the following equation: WBMS = 75.788 + (2.288 × load in kg of latissimus pull down) + (0.799 × lean body mass in kg). For men, the inclusion of either body mass (WBMS = 290.33 - [3.140 × age in years] + [1.236 × body mass in kg] + [1.549 × load in kg of leg press]) or, in particular, lean body mass (WBMS = 343.25 - [3.298 × age in years] + [.415 × lean body mass in kg] + [1.737 × load in kg of leg press]) decreased the standard error of the estimate. CONCLUSION: Our data support the idea that load correlates with body mass and lean body mass and that the load used for a specific exercise is significantly associated with WBMS, thereby permitting the development of a predictive model of WBMS with increased accuracy.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2016-01-02DOI: 10.5935/MedicalExpress.2016.01.08
M. Rocha-e-Silva
{"title":"MedicalExpress Year Three: SciELO and Sports Medicine Highlights","authors":"M. Rocha-e-Silva","doi":"10.5935/MedicalExpress.2016.01.08","DOIUrl":"https://doi.org/10.5935/MedicalExpress.2016.01.08","url":null,"abstract":"As we launch MedicalExpress Year Three, the journal begins its life in SciELO: within the next few weeks, our entire collection will become available at www.scielo.org. For Brazilian authors this means a reasonable to good QUALIS rating. All the articles included in this issue (nominally dated February, 2016) have been progressively uploaded to our site between December 15, 2015 and January 16, 2016. They may be read and downloaded from http:// www.medicalexpress.net.br/summary. Publication doesn’t get much faster out there, in Brazil or even worldwide. We would like to draw your attention to two studies in sports medicine: Cunha et al. offer a very useful report on the effects of a training program for elementary school teachers who do not have formal training in Physical Education, but must minister PE to their pupils. These teachers were submitted to a few weeks of training for specifics in Physical Education. Results monitored in their pupils were compared for those trained by teachers not","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2015-12-01DOI: 10.5935/MedicalExpress.2015.06.08
M. Rocha-e-Silva
{"title":"Two years seen out: MedicalExpress going stronger than ever","authors":"M. Rocha-e-Silva","doi":"10.5935/MedicalExpress.2015.06.08","DOIUrl":"https://doi.org/10.5935/MedicalExpress.2015.06.08","url":null,"abstract":"New journals cannot survive without friends: for who else, except real friends, would ever send papers to a journal that, to begin with, does not even exist, then barely survives; if it eventually finds its way into a serious database it begins to look at a real existence. So, this editorial celebrates two auspicious landmarks: MedicalExpress has made it into SciELO and is closing out volume two, year 2015; the entire collection will become visible in www.scielo.org sometime early next year. But even before appearing in SciELO, with nothing but Google Scholar and our own site (www. medicalexpress.net.br), we can boast close to 30 citations (and counting) to the 61 articles published in 2014. This means that we now have practically 0.5 citations/article. This is not an impact factor; it is better! For those familiar with the intricacies of this metric, 0.5 citations/year in the year immediately following publication foretells a pretty good Impact Factor twelve months hence. But at this point guesswork is still a dangerous sport. Published articles have been downloaded close to 35,000 times, 50 times/day. And we are sticking to our main offer: we publish in 40 ± 10 days after acceptance, which is faster than most of the competition. But far above celebrations, this is the time for a number of thank yous: MedicalExpress is forever indebted to the authors of the 100-plus papers, which were published throughout 2014-15 and paved the way for the future. As I said, new journals do not survive without friends. Thanks are also due to our sponsors, who believed in us to start from, and still apparently do. The last, certainly not least, “thanks a lot” simply has to go from the editor to his wife, Vera Lucia, who put up with a lot of anxiety, with numerous bouts of foul humor and who never failed to keep telling the editor that success was just around the corner. Did she really know? Did she really believe in it? It has often been said that smart ladies always know! It goes without saying that articles from the, oh so loyal friends are still hoped for, still expected, still","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"2 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2015-11-08DOI: 10.5935/MEDICALEXPRESS.2015.05.05
I. F. Moretti, Roseli da Silva, S. Oba-Shinjo, P. O. Carvalho, Lais C. Cardoso, I. Castro, S. Marie
{"title":"The impact of interleukin-13 receptor expressions in cell migration of astrocytomas","authors":"I. F. Moretti, Roseli da Silva, S. Oba-Shinjo, P. O. Carvalho, Lais C. Cardoso, I. Castro, S. Marie","doi":"10.5935/MEDICALEXPRESS.2015.05.05","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2015.05.05","url":null,"abstract":"INTRODUCTION: Astrocytomas are common brain tumors. Increased expression levels of Interleukin-13 Receptor α2 (IL-13RA2) have been reported in astrocytomas. The Interleukin-13 signaling pathway may be associated with cell migration when binding to Interleukin-13 Receptor α1. OBJECTIVE: To investigate Interleukin-13 Receptor α1 (IL-13RA1) and IL13RA2 expression levels in human diffusely infiltrative astrocytomas and test the involvement of Interleukin-13 levels in cell migration in two glioblastoma cell lines. METHODS: IL13RA expression levels were accessed by quantitative real time PCR in 128 samples of astrocytomas and 18 samples of non-neoplastic brain tissues from temporal lobe epilepsy surgery. The impact of IL-13 levels (10 and 20 ng/mL) on cell migration was analyzed by the wound assay in U87MG and A172 cells. RESULTS: Glioblastoma presented higher IL13RA1 and IL13RA2 expression levels compared to lower grades astrocytomas and to non-neoplastic cases. U87MG and A172 cells presented higher expression levels of IL-13RA1 vs. IL-13RA2. A significant difference in migration rate was observed in A172 cells treated with 10 ng/mL of IL-13 vs. control: treated cells presented slower migration than non-treated cells. U87MG cells treated with IL-13 20ng/mL presented slower migration than non-treated cells. This indicates that the IL13Rα1 signaling pathway was not activated, indeed inhibited by the decoy IL-13Rα2, slowing cell migration. This impact occurred with a lesser concentration of IL-13 on the A172 than on the U87MG cell line, because A172 cells have a higher IL-13RA2/A1 ratio. CONCLUSION: The present results suggest IL-13 receptors as possible targets to decrease tumor cell migration.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"2 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2015-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2015-10-31DOI: 10.5935/MEDICALEXPRESS.2015.06.02
E. Lattari, F. Paes, A. Machado, N. Rocha, A. Nardi, S. Machado
{"title":"Chronic effects of aerobic exercise on panic disorder: a systematic review of randomized and non-randomized trials","authors":"E. Lattari, F. Paes, A. Machado, N. Rocha, A. Nardi, S. Machado","doi":"10.5935/MEDICALEXPRESS.2015.06.02","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2015.06.02","url":null,"abstract":"BACKGROUND: In general, most studies have supported an association between the acute effects of exercise and a reduced state anxiety, but failed to completely explain the relationship between the chronic effect of exercise and anxiety traits. OBJECTIVE: The aim of this study was to systematically review the literature regarding the chronic effect of exercise on symptoms associated with panic disorder. METHODS: The studies were retrieved from a MEDLINE/PubMed, ISI Web of Knowledge and SciELO. We adopted PICOS’s strategy recommended to determine the eligibility criteria. The survey was conducted using an advanced search in the ISI Web of Science and MEDLINE / PubMed with MeSH terms and Entry Terms for the keywords “Panic Disorder” basis and “Exercise”. Boolean operators “AND” and “OR” were used separately or in combination. Two independent researchers performed the selection of studies; in case of disagreement they sought a consensus on the selection. RESULTS: A total of 265 articles were identified: 199 articles from PubMed/Medline, 63 articles from ISI Web of Science and 3 articles by manual searches. Thus, 31 articles were analyzed by the eligibility criteria and the exclusion criteria, a total of five studies included in the systematic review. CONCLUSION: The regular practice of aerobic exercise seems to be an appropriate intervention to promote improvements in the severity of anxiety symptoms in PD patients.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"2 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2015-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2015-10-20DOI: 10.5935/MEDICALEXPRESS.2015.06.07
E. Hiruma, M. Uchida, H. Sasaki, M. Umimura
{"title":"Heat pack treatment does not attenuate repeated muscle damage in collegiate females","authors":"E. Hiruma, M. Uchida, H. Sasaki, M. Umimura","doi":"10.5935/MEDICALEXPRESS.2015.06.07","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2015.06.07","url":null,"abstract":"OBJECTIVE: Unaccustomed exercise causes transient Delayed Onset Muscle Soreness (DOMS); creatine-kinase and DOMS are indirect markers of muscle damage. Heat pack treatment increases blood flow and relieves pain. We determined the effects of heat pack treatment on DOMS, Creatine-Kinase, pain and jumping following maximum calf-raise exercises. METHODS: Exercise (3 days): calf-raise, 1 movement every 3 seconds until subjects could not maintain movement speed, Recovery: monitored for 7 days. Subjects: 14 female collegiate students (age: 20-22) with previous regular moderate exercise history, divided into heat pack treatment (n = 7; 40oC, 20-min on both calf muscles immediately after exercise) vs. no treatment (n = 7). Measured parameters: number of daily movements, Creatine-Kinase, one-leg long jumping (JUMP) and perceived pain (PAIN). Maximum dorsiflexion, calf maximum circumference and isometric muscle strength were also measured, but showed no significant variation. RESULTS: There were no differences between groups regarding the number of the calf-raise repetitions; Creatine-Kinase increased significantly from day 3 of the Exercise-period to day 5 of the recovery period and peaked on Recovery day 2 in both groups; it was higher in the treated-group vs. controls; PAIN significantly decreased immediately after the heat pack treatment; DOMS peaked in both groups on day 3 of the Exercise-period, and recovered by day 4 of the recovery period. JUMP values decreased significantly after the initial exercise and recovered to initial values by Day 4 of the recovery period. CONCLUSION: Heat pack treatment for 20 minutes did not minimize DOMS following the maximum calf-raise exercise, but reduced immediate muscle soreness.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"2 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2015-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2015-10-01DOI: 10.5935/MEDICALEXPRESS.2015.05.07
M. Rocha-e-Silva
{"title":"MEDICALEXPRESS has been accepted for inclusion in SciELO and LILACS","authors":"M. Rocha-e-Silva","doi":"10.5935/MEDICALEXPRESS.2015.05.07","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2015.05.07","url":null,"abstract":"We are pleased to announce that MEDICALEXPRESS has been approved for inclusion into SciELO, the Scientific Electronic Library Online (www.scielo.org). This automatically determines that it also approved for inclusion in LILACS. SciELO is a highly respected multinational Science database, represented in 14 Latin American, Caribbean, European and African countries, with over 1,000 periodicals listed. It is a free open access collection, with a highly sophisticated search engine and operated as a permanent collection. In January, 2016, the entire collection of MEDICALEXPRESS, will become available in the SciELO site. This is probably the most important game changing fact in the eighteen-month life of this journal. Together with an extremely favorable rate of citations to our 2014 issue (25 citations to 61 articles – 0.41 cites/article – and counting), this may just be enough to obtain inclusion into the Science Citation Index (Impact Factor). The Editorial Office will make a decision on submission in November. This entire issue (MEDICALEXPRESS. 2015;2(5), October, is coming out ahead of schedule. All but one of the papers have been available ahead of print and the last one comes together with this editorial. All of the available articles have already been downloaded by interested parties. The highlights of this issue are Botelho et al demonstrated that transdermal testosterone enhances libido in periand postmenopausal women, with no undesirable side effects. Moretti et al showed that interleukin-13 receptors are possible therapeutic targets to prevent neoplastic cell migration in astrocytomas. Looking forward to your contribution to the journal. To the best of our knowledge, no Brazilian journal publishes as fast as we do.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"2 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2015-10-01DOI: 10.5935/MEDICALEXPRESS.2015.06.05
A. Barbosa, Moane Marchesan, A. V. Guimarães, Vivian Francielle França, M. Marucci, R. Coqueiro, M. Fernandes
{"title":"Anthropometric indicators and their adequacy in older adults from two towns in distinct Brazilian regions","authors":"A. Barbosa, Moane Marchesan, A. V. Guimarães, Vivian Francielle França, M. Marucci, R. Coqueiro, M. Fernandes","doi":"10.5935/MEDICALEXPRESS.2015.06.05","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2015.06.05","url":null,"abstract":"OBJECTIVE: To compare anthropometric indicators and their adequacy among older adults from two towns of distinct Brazilian regions. METHODS: A cross-sectional, population, and household-based epidemiological study. A total of 793 persons (age ≥ 60) from the Southern and Northeastern regions of Brazil were evaluated, according to age groups (60-69, 70-79, and ≥ 80 years) and sex. Data for body mass, height, body mass index, triceps skinfold thickness, arm muscle circumference, arm, waist and calf circumferences are presented. The prevalence of adequate anthropometric indicators was also compared for body mass index, arm circumference arm muscle circumference, triceps skinfold thickness, calf circumference and waist circumference. RESULTS: Subjects from the Southern region (n = 477) showed significantly greater mean values for all anthropometric variables vs. subjects from the Northeastern region (n = 316). Underweight (BMI 27.0 kg/m2) in the South. Older adults from the Northeast presented a higher proportion of adequate weight circumference. Other measured anthropometric indicators revealed a greater proportion of older adults with nutritional adequacy in the Southern region. CONCLUSION: This study provides information that can be used for anthropometric assessment of older adults in towns within the same context. Older adults of the two regions show vulnerable nutritional status, deficiency in the northeastern and excess in the southern region.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"2 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2015-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2015-09-25DOI: 10.5935/MEDICALEXPRESS.2015.06.03
L. B. Felix, A. D. Netto, Fernando de Souza Ranaudo, A. M. M. D. Sá
{"title":"A spatial coherence-based vision-free brain-computer interface using auditory selective attention","authors":"L. B. Felix, A. D. Netto, Fernando de Souza Ranaudo, A. M. M. D. Sá","doi":"10.5935/MEDICALEXPRESS.2015.06.03","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2015.06.03","url":null,"abstract":"INTRODUCTION: The development of Brain Computer Interfaces based on Auditory Selective Attention allows patients unable to voluntarily control eye movement to interact with the interface, because such systems are independent of vision. An alternative technique suitable for Brain Computer Interface applications is Spatial Coherence, an objective method to detect the side where a subject is focusing attention. This method takes into consideration the Coherence Function and the topographic distribution of responses between EEG electrodes. In this work, we further study the Information Transfer Rate and the effects of overlapping windows in the calculations. The idea behind the overlapping is to decrease the duration of the test in order to augment the Information Transfer Rate. METHOD: EEG signals were collected from fourteen adult men aged between 19 and 28 years. Amplitude-modulated tones were used for stimulation, with 32 and 38 Hz modulation and 500 and 2000 Hz carrier frequencies, on the left and right ears, respectively. Spatial coherence was used in an online Brain Computer Interface system using auditory steady-state responses modulated by Auditory Selective Attention. RESULTS: The obtained hit rates and the Information Transfer Rate may be considered appropriate, with a maximum value of 82% and 1.89 bits/min. The better detector regarding sensitivity versus specificity can be obtained by using a 50% overlap between consecutive data windows. CONCLUSION: We conclude that the Spatial Coherence successfully detected the focus of attention, and it seemed useful as a classifier of the attention condition for vision-free Brain Computer Interface.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"2 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2015-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5935/MEDICALEXPRESS.2015.06.03","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Medical ExpressPub Date : 2015-09-23DOI: 10.5935/MEDICALEXPRESS.2015.06.04
J. C. Pereira, M. P. Hallinan, J. H. Pessoa
{"title":"Excessively crying infants are more common among children of parents with restless legs syndrome","authors":"J. C. Pereira, M. P. Hallinan, J. H. Pessoa","doi":"10.5935/MEDICALEXPRESS.2015.06.04","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2015.06.04","url":null,"abstract":"OBJECTIVE: We have frequently observed that infants presenting with excessive crying and fussing, or colic at night have parents with Restless Legs Syndrome. Our objective was to determine if these infants are more likely to have parents with Restless Legs Syndrome (Willis-Ekbom Disease). METHODS: We interviewed 67 families with infants and children, in search of a history of excessive crying and fussing during their first four months of life. Their parents were investigated for Restless Legs Syndrome. RESULTS: Among the 134 interviewed parents, 39 (29%) had Restless Legs Syndrome. Among the 96 children, 37 (38%) presented excessive crying and fussing. Of these, 28 (76%) had at least one parent with Restless Legs Syndrome. Among the 59 children without excessive crying and fussing only 14 (24%) had at least one parent with Restless Legs Syndrome. The association between events (children of parents with vs. without Restless Legs Syndrome) was measured by the phi coefficient (0.510), indicating a more than trivial association. The estimated association was 75.7 vs. 27.7, Odds Ratio = 10 at 95% confidence interval, 3.82-26.15). CONCLUSION: Children with excessive crying and fussing were more likely to have at least one parent with Restless Legs Syndrome. The present evidence is insufficient to conclude that infantile excessive crying and fussing is equivalent to a a probable diagnosis of parental Restless Legs Syndrome. However, they provide information as well as the necessary motivation to undertake more extensive studies of infants with excessive crying and fussing.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"2 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2015-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71189411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}