Medical Express最新文献

McArdle’s disease: an underestimated or underdiagnosed myopathy in rheumatologic practice? Cases series and literature review McArdle病：风湿病实践中被低估或诊断不足的肌病？案例系列及文献综述

Medical Express Pub Date : 2018-10-06 DOI: 10.5935/MedicalExpress.2018.mo.008

P. Pallo, A. M. Silva, E. Zanoteli, S. Shinjo

引用次数: 1

Spontaneous pneumomediastinum in dermatomyositis: a case series and literature review 皮肌炎并发自发性纵隔气肿:一个病例系列和文献回顾

Medical Express Pub Date : 2018-07-02 DOI: 10.5935/MEDICALEXPRESS.2018.MO009

P. Pallo, S. Shinjo

{"title":"Spontaneous pneumomediastinum in dermatomyositis: a case series and literature review","authors":"P. Pallo, S. Shinjo","doi":"10.5935/MEDICALEXPRESS.2018.MO009","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2018.MO009","url":null,"abstract":"OBJECTIVES: To describe a case series of spontaneous pneumomediastinum in dermatomyositis and to review the literature. METHODS: This was a retrospective single-center case series, reporting 9 patients with pneumomediastinum and defined dermatomyositis, followed from 2005 to 2017. RESULTS: Median age of patients: 33 years; cutaneous and pulmonary involvement in all cases; constitutional symptoms in 88.8% of patients; involvement of the joints in 11.1%, gastrointestinal tract in 44.4%, and muscles in 77.7%; subcutaneous emphysema was observed in 55.5% and pneumothorax in 11.1%, respectively. Muscle weakness was observed in 77.7% of cases and with a median level of serum creatine phosphokinase of 124U/L. Drawing on results for our literature review, the overall analysis showed that the risk factors associated with spontaneous pneumomediastinum were: (a) a history of interstitial pneumopathy; (b) normal or low levels of muscle enzymes; (c) previous use of systemic glucocorticoid; (d) over 50% of patients had subcutaneous emphysema; (e) high mortality as a consequence of severity of the interstitial lung disease. CONCLUSIONS: Our case series revealed that pneumomediastinum is a rare complication in dermatomyositis that occurs in patients with a history of interstitial pneumopathy and may be accompanied by subcutaneous emphysema and pneumothorax.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":" ","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2018-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42578037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Cardiac vagal index varies according to field position in male elite football players 男性优秀足球运动员心脏迷走神经指数随场地位置的不同而变化

Medical Express Pub Date : 2018-05-20 DOI: 10.5935/MEDICALEXPRESS.2018.MO.006

CLAUDIO GIL ARAUJO, Altamiro Bottino, F. G. F. Pinto

{"title":"Cardiac vagal index varies according to field position in male elite football players","authors":"CLAUDIO GIL ARAUJO, Altamiro Bottino, F. G. F. Pinto","doi":"10.5935/MEDICALEXPRESS.2018.MO.006","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2018.MO.006","url":null,"abstract":"BACKGROUND: Cardiac vagal index (CVI) is supposedly higher in athletes and may differ between sports and/or between field positions. OBJECTIVE: To compare CVI: a) between elite football players vs. non-athletes and b) according to five football positions. METHOD: 242 football players of the first Brazilian/Angolan division were divided in five positions (N): goalkeepers (17), defenders (44), wingers (34), midfielders (87) and forwarders (60) and compared with 303 age-matched healthy non-athletes. CVI was estimated from a 4-second exercise test by quantifying the ratio of two cardiac cycle durations, before and at the end of a fast unloaded cycling exercise. RESULTS: Football players had resting and maximal heart rates of, respectively, 59 and 190 bpm and measured VO2max of 62.2 mL/(kg.min). Players and non-athletes showed similar CVI results (median-[P25-P75]) – 1.63[1.46-1.84] vs 1.61-[1.41-1.81] (p = 0.22). Wingers tended to have a higher CVI (1.84-[1.60-1.99]), especially when compared to defenders (1.53-[1.41-1.72] (p = 0.01). There was a modest non-physiologically relevant association between VO2max and CVI (r = 0.15). CONCLUSIONS: Football players did not differ from non-athletes in CVI; however, among players, wingers were more often vagotonic, which may represent a hemodynamic advantage for match situations, where rapid heart rate transitions and faster oxygen delivery to muscles are required.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":" ","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2018-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47768187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The influence of exercise order on strength performance in post menopause women 运动顺序对绝经后妇女力量表现的影响

Medical Express Pub Date : 2018-05-16 DOI: 10.5935/MEDICALEXPRESS.2018.MO.005

J. Jesus, A. Brown, Diogo Cardozo, L. G. Santos, Ingrid Dias, Fábio Cahuê, V. Salerno, R. Simão

{"title":"The influence of exercise order on strength performance in post menopause women","authors":"J. Jesus, A. Brown, Diogo Cardozo, L. G. Santos, Ingrid Dias, Fábio Cahuê, V. Salerno, R. Simão","doi":"10.5935/MEDICALEXPRESS.2018.MO.005","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2018.MO.005","url":null,"abstract":"OBJECTIVE: Verify the influence of different exercise orders on the performance of the number of maximal repetitions in older women. METHODS: Twelve older women (65.7 ± 5.6 years, 66.9 ± 9.5 kg, 1.56 ± 0.67 m, 27.4 ± 3.6 kg/m2) underwent four nonconsecutive visits and two different orders of Resistance Training. At the first visit, the volunteers were submitted to anamnesis, anthropometric evaluation and a 10RM test. On the second visit, a re-test of 10RM was performed. On the third and fourth visits, the volunteers performed two exercise sequences: sequence A: bench press, latissimus pulldown close grip, biceps curl, triceps extension; for sequence B the order was inverted. Performance was measured by the number of repetitions in each exercise. To determine differences in performance for sequence A vs. sequence B, repeated measures were performed by two-way ANOVA followed by the Tuckey post-hoc test. RESULTS: The number of repetitions of each exercise varied significantly for the bench press, biceps curl and triceps extension between the exercise sequences. CONCLUSIONS: The order of the exercises performed in a resistance training session can affect the performance in the number of repetitions in older women.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"5 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2018-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5935/MEDICALEXPRESS.2018.MO.005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47424436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Application of adiposity indices to a sample of physically active individuals living in the city of Ribeirão Preto, São Paulo, Brazil 肥胖指数在巴西圣保罗Ribeirão Preto市体力活动人群样本中的应用

Medical Express Pub Date : 2018-04-14 DOI: 10.5935/MEDICALEXPRESS.2018.MO.004

M. Mialich, A. Aiello, B. R. Silva, A. Jordão

{"title":"Application of adiposity indices to a sample of physically active individuals living in the city of Ribeirão Preto, São Paulo, Brazil","authors":"M. Mialich, A. Aiello, B. R. Silva, A. Jordão","doi":"10.5935/MEDICALEXPRESS.2018.MO.004","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2018.MO.004","url":null,"abstract":"OBJECTIVE: To compare adiposity indexes in physical activity individuals to evaluate behavior, diagnostic ability and to determine which parameter best reflects and diagnoses body fatness. METHODS: A cross-sectional study was performed on 100 physically active individuals (59% female). The participants were submitted to anthropometric and body composition evaluation; we measured weight, height, circumferences, blood pressure and bioelectrical impedance analysis. A physical activity questionnaire (IPAQ, short version) was applied, as well as a questionnaire about the possible use of nutritional supplementation. The data were statistically analyzed, with significance level set at p <0.05. RESULTS: Mean age, height, weight and BMI were 24.2 ± 6.65 years, 169.5 ± 8.94 cm, 69.1 ± 14.83 kg and 23.9 ± 4.19 kg/m2 , respectively, with a significant difference between the genders, except for age. Most of the subjects were in the normal weight range, with a BMI of 18.5 to 24.9 kg/m2, and were very active. BMIfat correlated better with body fat for males (r = 0.896) and females (r = 0.935), followed by BMI (0.689 and 0.767, respectively) and BAI (0.590 and 0.718). CONCLUSIONS: Adiposity indexes are viable alternatives for the diagnosis of obesity and should be more explored as fast, practical and low cost measures in clinical practice.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":" ","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45943469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Insulin resistance is increased in adult patients with dermatomyositis 成人皮肌炎患者胰岛素抵抗增加

Medical Express Pub Date : 2018-04-10 DOI: 10.5935/MEDICALEXPRESS.2018.MO.003

D. S. Oliveira, Marilda Silva Guimarães, S. Shinjo

{"title":"Insulin resistance is increased in adult patients with dermatomyositis","authors":"D. S. Oliveira, Marilda Silva Guimarães, S. Shinjo","doi":"10.5935/MEDICALEXPRESS.2018.MO.003","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2018.MO.003","url":null,"abstract":"OBJECTIVE: To evaluate insulinemia in glucocorticoid naïve patients with dermatomyositis and to evaluate insulin resistance using the homeostatic model assessment of insulin resistance (HOMA2-IR). METHODS: This cross-sectional study included 25 dermatomyositis, non-diabetic glucocorticoid naïve patients. The control group consisted of 50 volunteers matched for age, gender, ethnicity, weight and height. The HOMA2IR index was calculated from baseline insulin and glucose data. The International Myositis Assessment & Clinical Studies Group (IMACS) parameters were used to evaluate disease status. RESULTS: Mean age of the patients was 43.5 years and these were predominantly females. Patients had low disease activity according to IMACS parameters. Higher body mass index and waist circumference were observed in the dermatomyositis group compared to the control group. Insulin level and HOMA2-IR were also higher in patients with dermatomyositis. Moreover, analyzing dermatomyositis alone, the HOMA2-IR index correlated positively with weight, body mass index and waist circumference and was independent on disease status parameters. CONCLUSIONS: Patients with dermatomyositis had higher values for basal insulinemia, insulin resistance, body mass index and waist circumference. Moreover, HOMA2-IR moderately correlated with these anthropometric parameters. These metabolic abnormalities are related to the development of metabolic syndrome, one of the main comorbidities observed in dermatomyositis.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":" ","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46910099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Medical Express Pub Date : 2018-04-02 DOI: 10.5935/MEDICALEXPRESS.2018.MO.007

J. Greve, Marcelo Rosa Resende, H. Carvalho, G. Andreuccetti, C. Bernini, V. Leyton

{"title":"Factors related to motorcycle accidents with victims: an epidemiological survey","authors":"J. Greve, Marcelo Rosa Resende, H. Carvalho, G. Andreuccetti, C. Bernini, V. Leyton","doi":"10.5935/MEDICALEXPRESS.2018.MO.007","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2018.MO.007","url":null,"abstract":"OBJECTIVE: To evaluate the factors associated with traffic motorcycles accidents. METHODS: The sample consisted of 285 motorcycle accident victims in São Paulo. Data were collected from 24-hour emergency service shifts regarding: conditions of the victims, security equipment, road and vehicle conditions. RESULTS: Victims were mostly young men (92%); 23% used the motorcycle for work (average: 8 hours per day); 45% had owned a motorcycle for less than two years; 77% were licensed motorcycle drivers; 33% had less than four years of qualification; 31% had attended a course of defensive driving. Severe lesions were identified in 67% of the unlicensed drivers. Polytrauma occurred in 9% head trauma in 5% of the entire population. Lower limb fractures occurred more frequently than upper limb (17% vs. 12%). Most wore helmets (90%) but only 18% wore helmet, boots and jacket. Positive readings for alcohol (7%) and drugs (14%) occurred in 21% of victims. Most accidents occurred as a consequence of imprudence (88%), during the day (67%), in dry weather conditions (94%). A side impact was registered in 48% of cases; 80% of motorcycles had an engine capacity up to 250 cc. In 51% of the accidents the person responsible for the accident was the driver of the other vehicle in the accident. CONCLUSION: Most accidents involve motorcyclists who are young male adults, use the motorcycle as a means of transport and do not consider safety, defensive driving and the use of alcohol and drugs as important factors.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":"5 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2018-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42154059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Patients with pure dermatomyositis/polymyositis and anti-PM/Scl autoantibody resembling anti-synthetase syndrome 单纯皮肌炎/多发性肌炎合并抗pm /Scl自身抗体类似抗合成酶综合征的患者

Medical Express Pub Date : 2018-03-02 DOI: 10.5935/MEDICALEXPRESS.2018.MO.002

Samara Pereira Alves, M. G. Silva, I. Borges, S. Shinjo

{"title":"Patients with pure dermatomyositis/polymyositis and anti-PM/Scl autoantibody resembling anti-synthetase syndrome","authors":"Samara Pereira Alves, M. G. Silva, I. Borges, S. Shinjo","doi":"10.5935/MEDICALEXPRESS.2018.MO.002","DOIUrl":"https://doi.org/10.5935/MEDICALEXPRESS.2018.MO.002","url":null,"abstract":"OBJECTIVE: The anti-PM/Scl autoantibody has been described in patients with scleromyositis. However, there are scant studies evaluating its prevalence and reactivity in dermatomyositis and polymyositis. METHOD: A cross-sectional, single center study evaluating the anti-PM/Scl autoantibody in 85 dermatomyositis and 32 polymyositis patients, without overlapping syndrome, was conducted between 2000 and 2016. Clinical data and complementary examinations were reviewed from electronic medical records with pre-parameterized information. RESULTS: The mean age of dermatomyositis and polymyositis patients was 41.1 and 42.8 years, respectively. The presence of anti-PM/Scl was observed in 5 (5.9%) dermatomyositis and 2 (6.3%) polymyositis patients. Two of these patients also had the anti-Ku antibody. The relevant clinical manifestations of these 7 patients were constitutional symptoms (100% of cases), muscular (100%), pulmonary (85.7%) and joint (71.4%) involvement, “mechanic hands” (85.7%), Raynaud phenomenon (85.7%) and plantar hyperkeratosis (85.7%). The 7 patients had relapses of disease activity, but at conclusion of the present study, 5 had complete clinical response and 2 complete remission of the disease. CONCLUSION: There is a low frequency of the anti-PM/Scl autoantibody in dermatomyositis and polymyositis patients. In addition, patients with this autoantibody exhibit a similar pattern of manifestations to that of antisynthetase syndrome.","PeriodicalId":31471,"journal":{"name":"Medical Express","volume":" ","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2018-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42871810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Rapid progression of neurotoxoplasmosis in a patient with concomitant rheumatoid arthritis and systemic lupus erythematous 伴发类风湿性关节炎和系统性红斑狼疮的患者神经氧体病的快速进展

Medical Express Pub Date : 2018-02-25 DOI: 10.5935/MEDICALEXPRESS.2018.ML.002

M. Oliveira, C. B. Pereira, Vitor Brito SilvaI, M. Costa, V. Paes, R. Ibrahim

引用次数: 2

The Importance of Oral Health during Pregnancy: A review 孕期口腔健康的重要性:综述

Medical Express Pub Date : 2018-01-20 DOI: 10.5935/MEDICALEXPRESS.2018.MR.002

V. Marla, R. Srii, D. Roy, Hardik Ajmera

引用次数: 32