伴发类风湿性关节炎和系统性红斑狼疮的患者神经氧体病的快速进展

M. Oliveira, C. B. Pereira, Vitor Brito SilvaI, M. Costa, V. Paes, R. Ibrahim
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引用次数: 2

摘要

尊敬的编辑弓形虫病是最常见的人类感染之一。全世界约有三分之一的人口感染了潜伏性弓形虫病。1-6中枢神经系统(CNS)弓形虫病的发生是由于先前潜伏性感染的重新激活。患者通常表现为发烧、头痛、意识受损、癫痫发作和/或局灶性神经功能缺损。1-5中枢神经系统弓形虫病可能会使获得性人类免疫缺陷(如艾滋病)、免疫系统疾病或长期药物免疫抑制治疗的患者的临床病程复杂化。1-5因为临床图片和诊断具有挑战性,神经氧合胞体病可能与其他几种中枢神经系统疾病相似,特别难以控制,经常需要经验性治疗。1-5我们报告了一例在伴有类风湿性关节炎和系统性红斑狼疮(SLE)的患者中发生的神经氧合细胞病的不寻常病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Rapid progression of neurotoxoplasmosis in a patient with concomitant rheumatoid arthritis and systemic lupus erythematous
Dear Editor Toxoplasmosis is one of the most common human infections. About one-third of the entire world population is infected with latent toxoplasmosis.1-6 Central nervous system (CNS) toxoplasmosis occurs due to reactivation of previous latent infection. Patients usually present with fever, headache, impaired consciousness, seizures, and/ or focal neurological deficits.1-5 CNS toxoplasmosis may complicate the clinical course of patients with acquired human immunodeficiency (e.g. AIDS), immune system disease, or prolonged pharmacologic immunosuppressive treatment.1-5 Because the clinical picture and diagnosis are challenging, neurotoxoplasmosis may mimic several other CNS disorders, being especially difficult to manage and frequently requiring empiric treatment.1-5 We present an unusual case of neurotoxoplasmosis developing in a patient with concomitant rheumatoid arthritis and systemic lupus erythematous (SLE).
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