Caspian Journal of Neurological Sciences最新文献_第3页

Abductor Pollicis Brevis/Abductor Digiti Minimi Compound Muscle Action Potential Ratio as a Diagnostic Marker for Amyotrophic Lateral Sclerosis 短拇外展肌/小指外展肌复合肌动作电位比值作为肌萎缩性侧索硬化的诊断指标

Caspian Journal of Neurological Sciences Pub Date : 2023-07-01 DOI: 10.32598/cjns.9.34.387.1

Majid Ghasemi, M. Alizadeh, K. Basiri, B. Ansari, R. Tayebi Khorami

{"title":"Abductor Pollicis Brevis/Abductor Digiti Minimi Compound Muscle Action Potential Ratio as a Diagnostic Marker for Amyotrophic Lateral Sclerosis","authors":"Majid Ghasemi, M. Alizadeh, K. Basiri, B. Ansari, R. Tayebi Khorami","doi":"10.32598/cjns.9.34.387.1","DOIUrl":"https://doi.org/10.32598/cjns.9.34.387.1","url":null,"abstract":"Background: We aimed to assess the diagnostic utility of abductor pollicis brevis/abductor digiti minimi compound muscle action potentials (APB/ADM CMAP) ratio as an indicator of split hand phenomenon in the differentiation of amyotrophic lateral sclerosis (ALS) patients from healthy controls. Objectives: To assess diagnostic utility of APB/ADM CMAP ratio as an indicator split hand phenomenon in differentiation of ALS patients from healthy controls. Materials & Methods: This cross-sectional retrospective study was conducted at Alzahra and Kashani hospitals of Isfahan, Iran, in 2021. The study population consisted of all patients with definite diagnoses of ALS who had undergone electrophysiological studies within the previous 5 years. APB/ADM CMAP ratio was calculated in both groups based on right/left hand and below/ over 50 years of age. The statistical analysis also evaluated the diagnostic accuracy of the APB/ ADM amplitude ratio. Results: A total of 200 ALS patients and 200 healthy controls were evaluated. APB/ADM ratios of the right hand in the controls and patients were 1.27±0.71 and 1.27±1.69 (P=0.961), while in the left hand, these figures were 1.30±0.54 and 1.11±0.97, respectively (P=0.018). Analysis based on age group revealed a significant difference in the APB/ADM amplitude ratio in the left hand of individuals younger than 50. The cut-off points of 0.81 (sensitivity=86.2% and specificity=58.7%) and 1.03 (sensitivity=72.5% and specificity=58.5%) were calculated for right and left hands, respectively. Conclusion: APB/ADM CMAP ratio is a relatively highly sensitive but moderately specific diagnostic marker for differentiating ALS patients from healthy controls with higher diagnostic utility in patients younger than 50.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84512177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Series of Cerebral Venous Sinus Thrombosis After COVID-19 Vaccination 新型冠状病毒疫苗接种后脑静脉窦血栓形成病例系列

Caspian Journal of Neurological Sciences Pub Date : 2023-07-01 DOI: 10.32598/cjns.9.34.399.1

M. Soltani, Nasrin Salimnia, M. Nahayati, Maryam Payere

引用次数: 0

Effectiveness of Behavior Management Intervention in Migraine With a Focus on Comorbid Depressive 行为管理干预偏头痛的有效性，重点是共病抑郁症

Caspian Journal of Neurological Sciences Pub Date : 2023-07-01 DOI: 10.32598/cjns.9.34.350.1

Kimia Safarionpur, A. Zebardast, A. Saberi

{"title":"Effectiveness of Behavior Management Intervention in Migraine With a Focus on Comorbid Depressive","authors":"Kimia Safarionpur, A. Zebardast, A. Saberi","doi":"10.32598/cjns.9.34.350.1","DOIUrl":"https://doi.org/10.32598/cjns.9.34.350.1","url":null,"abstract":"Background: Migraine negatively affects sufferers’ physical and mental health and social and economic status. Objectives: This study compared the effectiveness of behavior management therapy and pharmacotherapy in reducing migraine-related disabilities with and without focusing on comorbid depressive symptoms. Materials & Methods: This quasi-experimental study has a pre-test-post-test design with a control group. The study was conducted on migrainous patients with comorbid depressive symptoms referred to neurology clinics in Rasht City, Iran, in 2021. A total of 18 female patients were selected using purposive sampling based on neurological diagnosis and the diagnostic and statistical manual of mental disorders (DSM-5) criteria for depressive disorder. The participants were randomly assigned to two groups after matching regarding age and severity of depression. Combined therapy (behavior management intervention [BM] and pharmacotherapy [P]) was performed in two groups during eight sessions, with (case group) and without (control group) focusing on comorbid depressive symptoms. The data were collected using the Beck depression inventory (BDI-II), the headache disability inventory (HDI) , and the headache diary (HD) and analyzed using multivariate analysis of covariance. Results: The first therapeutic approach was significantly superior to the second in reducing migraine-related disabilities (F(2, 13)=10.43, P<0.05, Wilks Lambda=0.384, partial Ƞ2=0.616). Conclusion: Combined therapy (BM & P) focusing on comorbid depressive symptoms can be an alternative or complementary therapeutic method to reduce various disabilities in migraine patients.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82366410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-glaucomatous Optic Disc Cupping: A Brief Review 非青光眼性视盘拔火罐:简要回顾

Caspian Journal of Neurological Sciences Pub Date : 2023-07-01 DOI: 10.32598/cjns.9.34.417.1

Hassan Behboudi, Ebrahim Azaripour

{"title":"Non-glaucomatous Optic Disc Cupping: A Brief Review","authors":"Hassan Behboudi, Ebrahim Azaripour","doi":"10.32598/cjns.9.34.417.1","DOIUrl":"https://doi.org/10.32598/cjns.9.34.417.1","url":null,"abstract":"Although optic disc cupping is mostly seen in glaucoma patients, it can occur in non-glaucomatous optic neuropathies (NGON). The characteristics of NGON are cupping toxic optic neuropathies, optic neuritis, compressive ischemia, and hereditary nature. The basic components of optic disc cupping are prelaminar and laminar. Prelaminar thinning, which seemed to be non-specific, occurs in all types of retinal ganglion cell axon loss; such as compressive, ischemic, and inflammatory events; glaucoma; and aging. This form of cupping is usually shallow, with less excavation of the optic disc. Laminar type of cupping which is a clinically profound type of cupping, may damage peripapillary scleral and lamina cribrosa. Sometimes experienced clinicians cannot clearly distinguish glaucomatous from non-glaucomatous cupping. The non-glaucomatous optic neuropathy has more neuroretinal rim pallor with less excavation of the disc than in glaucoma. It also involves central visual acuity and color vision in primary levels with visual field defects aligned vertically and respecting the midline. Evaluation of the patient’s medical records, disease presentation, ocular function, and examination are also crucial. Secondary examinations, including visual field examination and optical coherence tomography (OCT) or neuroimaging, facilitate the disease’s differentiation. This review presents the methods of examining a patient with an increased cup-to-disc ratio.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80008628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation of Healthy Aging Brain Care Monitor Selfreport Questionnaire in Patients With Post-intensive Care Syndrome 重症监护后综合征患者健康老化脑保健监测自我报告问卷的验证

Caspian Journal of Neurological Sciences Pub Date : 2023-07-01 DOI: 10.32598/cjns.9.34.391.2

Mehdi Ahmadi, Simin Jahani, Amir Elhaee, N. Sayadi

{"title":"Validation of Healthy Aging Brain Care Monitor Selfreport Questionnaire in Patients With Post-intensive Care Syndrome","authors":"Mehdi Ahmadi, Simin Jahani, Amir Elhaee, N. Sayadi","doi":"10.32598/cjns.9.34.391.2","DOIUrl":"https://doi.org/10.32598/cjns.9.34.391.2","url":null,"abstract":"Background: Many survivors of intensive care units experience functional disabilities and significant physical, mental, and perceptive impairments known as post-intensive care syndrome (PICS). Objectives: This research intended to translate and examine the psychometric properties of the Persian version of the healthy aging brain care monitor self-report (HABC-M-SR). Materials & Methods: This methodological research was directed to ascertain the psychometric properties of the Persian version of HABC-M-SR (p-HABC). This study was conducted in Ahvaz City, Iran, in 2021. The HABC-M-SR was translated into Persian. Face validity, content validity index, and content validity ratio were examined. Exploratory and confirmatory factor analyses were performed on 500 samples. The Cronbach α and interclass correlation coefficients were calculated to check the reliability. Results: Regarding the quantitative and qualitative face and content validity assessments, all items were suitable for further analysis, with a content validity index >0.79 and a content validity ratio >0.62. Afterward, exploratory factor analysis was implemented on 270 subjects assuming that three factors were constant on the questionnaire. Also, questions 7, 8, 9, and 12 were removed due to low factor loading, and confirmatory factor analysis was performed on 23 questions. Finally, 230 samples were taken, and the results were almost within the acceptable range. The Cronbach α (0.828) and interclass correlation coefficient (0.752) were satisfactory results. Conclusion: The p-HABC showed acceptable psychometric properties and can be used to screen for PICS. The p-HABC can trigger further studies on early diagnosis and management of PICS in ICU survivors in Iran.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87450994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraosseous Cavernous Hemangioma of the Neurocranium: A Review of the Literature 神经颅骨骨内海绵状血管瘤:文献综述

Caspian Journal of Neurological Sciences Pub Date : 2023-04-01 DOI: 10.32598/cjns.9.33.400.1

A. Curcio, Lucia Maria Cecilia Dimitri, C. Copelli, Leonardo Pio Gorgoglione, A. Germanò, D. Catapano

引用次数: 0

Bilateral Optic Neuritis After Administration of Inactivated COVID-19 Vaccine: A Case Report COVID-19灭活疫苗后双侧视神经炎1例报告

Caspian Journal of Neurological Sciences Pub Date : 2023-04-01 DOI: 10.32598/cjns.9.33.393.1

Evaliza Villoria, Prima Quintay, Elin Dela Cruz, Artemio Roxas Jr

{"title":"Bilateral Optic Neuritis After Administration of Inactivated COVID-19 Vaccine: A Case Report","authors":"Evaliza Villoria, Prima Quintay, Elin Dela Cruz, Artemio Roxas Jr","doi":"10.32598/cjns.9.33.393.1","DOIUrl":"https://doi.org/10.32598/cjns.9.33.393.1","url":null,"abstract":"Background: Since the beginning of the COVID-19 pandemic, various efforts have been taken to alleviate the spread of the severe acute respiratory syndrome coronavirus 2 (SARS CoV2). Studies have shown effective prevention and protection through vaccination. However, there have also been reports of neurologic diseases after vaccination. Case Presentation: The first case in the Philippines belonged to a 25-year-old female who initially sought a consult for the increased sleeping time associated with retrograde amnesia immediately after receiving her second dose of inactivated SARS-CoV-2 vaccine. She was then managed as a case of viral encephalitis. However, two weeks later, the patient developed a bilateral decline in visual acuity. Diagnostics included visual perimetry, routine EEG, contrast enhanced cranial MRI, and visual evoked potentials. The patient was then managed as a case of bilateral optic neuritis and was started on pulse methylprednisolone for 3 days with noted gradual but incomplete reversal of the condition. Conclusion: Autoimmune neurologic events after COVID-19 vaccination are treatable, and the benefits of the vaccination outweigh its risk.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83712582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Bridging Integrator 1 Gene Polymorphism and Susceptibility to Alzheimer’s Disease 桥接整合子1基因多态性与阿尔茨海默病易感性的关系

Caspian Journal of Neurological Sciences Pub Date : 2023-04-01 DOI: 10.32598/cjns.9.33.6

A. Saberi, Zohair Niroomand, A. Ghayeghran, F. Ajamian, Ashkan Karimi, Samaneh Ghorbani Shirkouhi, L. Mirzanejad, Somayeh Ahmadi Gooraji, S. Andalib

{"title":"The Relationship Between Bridging Integrator 1 Gene Polymorphism and Susceptibility to Alzheimer’s Disease","authors":"A. Saberi, Zohair Niroomand, A. Ghayeghran, F. Ajamian, Ashkan Karimi, Samaneh Ghorbani Shirkouhi, L. Mirzanejad, Somayeh Ahmadi Gooraji, S. Andalib","doi":"10.32598/cjns.9.33.6","DOIUrl":"https://doi.org/10.32598/cjns.9.33.6","url":null,"abstract":"Background: Alzheimer’s Disease (AD) is the most common type of dementia. The role of genetic factors in AD development remains non-demonstrated. Objectives: In this study, we aimed to investigate the association between one of the BIN1 gene’s single-nucleotide polymorphisms (SNP) rs744373 and Late-Onset Alzheimer’s Disease (LOAD) in an Iranian population in Guilan Province. Materials & Methods: In this case-control study, 110 patients with LOAD and 110 unrelated healthy controls were recruited. Polymerase chain reaction-restriction length polymorphism (PCRRFLP) was performed for genotyping the BIN1 gene’s SNP rs744373. Electrophoresis was thereafter conducted using agarose gel and DNA-safe stain, and the gels were visualized under an Ultraviolet (UV) trans-illuminator. The allelic and genotypic frequencies were determined. Results: The frequency of allele T (Wild-type allele) in the control and the LOAD groups was 70.9% (n=159) and 58.6% (n=129), respectively (P=0.007). The frequency of allele C in the LOAD group (41.4%) (n=91) was significantly higher than that of the control group (29.1%) (n=64) (P=0.007). BIN’s homozygous genotype (CC) frequency was significantly higher in the LOAD group than in the control group (P=0.043). Conclusion: The rs744373 SNP of the BIN1 gene is significantly associated with the risk of developing AD in the studied population.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84015386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association Between Depression and Activity of Inflammatory Bowel Disease 抑郁与炎症性肠病活动之间的关系

Caspian Journal of Neurological Sciences Pub Date : 2023-04-01 DOI: 10.32598/cjns.9.33.390.1

F. Joukar, M. Asgharnezhad, N. Faraji, Tahereh Zeinali, A. Hojati, Sara Maveddati, M. Sepehrimanesh, Adele Isanazar, A. Mansour-Ghanaei, A. Samadi, F. Mansour-Ghanaei

{"title":"The Association Between Depression and Activity of Inflammatory Bowel Disease","authors":"F. Joukar, M. Asgharnezhad, N. Faraji, Tahereh Zeinali, A. Hojati, Sara Maveddati, M. Sepehrimanesh, Adele Isanazar, A. Mansour-Ghanaei, A. Samadi, F. Mansour-Ghanaei","doi":"10.32598/cjns.9.33.390.1","DOIUrl":"https://doi.org/10.32598/cjns.9.33.390.1","url":null,"abstract":"Background: The association between depression and inflammatory bowel disease (IBD) has been reported worldwide. Objectives: We aimed to investigate the prevalence of active and inactive IBD depression and its associated risk factors among patients with depression and IBD. Materials & Methods: In this cross-sectional study, demographic data and clinical characteristics of 156 IBD patients referred to Razi Hospital, Rasht City, Iran, were recorded from 2015 to 2016. The Beck depression inventory (BDI) was administered to all patients, and their scores were classified as no, mild, moderate, and severe depression. Modified Truelove and Witts severity index (MTWSI) for ulcerative colitis (UC) and Harvey Bradshaw severity index (HBSI) for Crohn’s disease (CD) were used to quantitate IBD activity as active UC (scored ≥10) and active CD (scored ≥7). Results: About 35.9% of the patients (n=56) had depression. Patients with active IBD had significantly higher BDI scores than those with inactive IBD (14.41±10.34 vs 10.14±10.28, respectively, P=0.011). Except for income (P=0.001), no significant associations were detected between IBD status and other background variables (P>0.05). No patients in either active or inactive IBD groups had cancers. Based on the severity of depression, the patients were grouped as follows: 64.1% had no depression, 30.1% had mild depression, 5.8% had moderate depression, and 0.0% had severe depression. However, significant positive associations were seen between an increase in depression severity and having autoimmune diseases, a lower education level, and a history of IBD-related surgeries. Conclusion: It seems that patients with active IBD are more depressed than inactive IBD patients.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87616939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional Gait Assessment Tests in Elderly: A Systematic Review 老年人功能性步态评估试验:系统综述

Caspian Journal of Neurological Sciences Pub Date : 2023-04-01 DOI: 10.32598/cjns.9.32.295.3

A. Norasteh, Esmail Balayi, H. Zarei

{"title":"Functional Gait Assessment Tests in Elderly: A Systematic Review","authors":"A. Norasteh, Esmail Balayi, H. Zarei","doi":"10.32598/cjns.9.32.295.3","DOIUrl":"https://doi.org/10.32598/cjns.9.32.295.3","url":null,"abstract":"Background: Due to the mobility problems of the elderly, it is better to use low-cost and applicable methods in any place, which do not require expertise to measure gait. One of these ubiquitous methods is functional gait assessment (FGA). Objectives: The purpose of this study was to collect and evaluate FGA in the elderly. Materials & Methods: This study conducted a comprehensive study of FGA in the elderly by searching the databases of PubMed, MEDLINE, Web of Science, ScienceDirect, Cochrane Central Register of Controlled Clinical Trials, Google Scholar, Scopus, MAGIRAN, IRANDOC, Iran Medex, MedLib, and SID from 1996 to November 2020. After compiling the search results, we first studied the titles and then the abstracts. If an article matched the inclusion and exclusion criteria, its results were used in the review study; otherwise, it was excluded. Results: Based on the research criteria and objectives, from 23 different tests, the results of 19 articles that studied FGA in the elderly were selected and reported. Conclusion: Studies seem to attempt FGA in the elderly using different methods and for different purposes. For example, studies to assess gait velocity, normal gait, and gait, along with functional and cognitive tasks, have measured FGA in the elderly. Besides, the two main features of a valid test including sensitivity and specificity have been less studied. Therefore, more studies should focus on these test features in measuring FGA in the elderly.","PeriodicalId":31302,"journal":{"name":"Caspian Journal of Neurological Sciences","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81170609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0