{"title":"Medical Diagnostics of Quantum Dot-Based Protein Micro- and Nanoarrays","authors":"A. Gokarna, Yong‐Hoon Cho","doi":"10.1002/9783527610419.NTLS0195","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0195","url":null,"abstract":"The sections in this article are \u0000 \u0000 \u0000Introduction \u0000Invention of Protein Microarrays \u0000Optical Readout of Protein Arrays: Traditional versus New Labels \u0000 \u0000 \u0000Protein Arrays \u0000The Various Types of Protein Array \u0000Methods of Optical Detection in Protein Arrays Using Labeled Probes \u0000 \u0000 \u0000From Microarrays to Nanoarrays: Why Nanoarrays? \u0000Functionalization of QDs for Attachment to Proteins or Other Biomolecules \u0000Fabrication of Protein Biochips \u0000Printing of QDs-Conjugated Protein Microarray Biochips \u0000Nanoarray Protein Chips Using QDs \u0000 \u0000 \u0000QDs Probes in Clinical Applications \u0000Detection of Disease (Cancer) Biomarkers Using QD Labels \u0000Certain Limitations in QDs Labeled Microarrays: Nonspecific Binding Effects \u0000QDs versus Organic Dyes in Protein Microarrays \u0000Multiplexing in Protein Microarrays Using QDs \u0000 \u0000 \u0000QDs-Labeled Protein Nanoarrays \u0000Summary and Future Perspectives \u0000Acknowledgments \u0000 \u0000 \u0000Keywords: \u0000 \u0000quantum dots; \u0000protein microarrays; \u0000nanoarrays; \u0000biochips; \u0000biomarkers; \u0000organic dyes","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126223032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gold Nanofilms: Synthesis, Characterization, and Potential Biomedical Applications","authors":"S. Tokonami, H. Shiigi, T. Nagaoka","doi":"10.1002/9783527610419.NTLS0183","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0183","url":null,"abstract":"The sections in this article areIntroductionPreparation of Various AuNPsFunctionalization of AuNPs and their Applications through AggregationAuNP Assemblies and ArraysAuNP Assemblies Structured on SubstratesAuNP Assembly on BiotemplatesAuNP Arrays for Gas SensingAuNP Arrays for BiosensingConclusionsKeywords:biosensor;nanoparticle;gold nanoparticle;nanoparticle array;DNA detection;immunoassay","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124339686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nanomaterials‐Based Magnetic Relaxation Switch Biosensors","authors":"T. Lowery","doi":"10.1002/9783527610419.NTLS0163","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0163","url":null,"abstract":"The sections in this article are \u0000 \u0000 \u0000Introduction \u0000Superparamagnetic Nanoparticles \u0000Agglomeration-Based Sensing \u0000T2 Sensitivity of MRSW Particles \u0000Fundamentals of T2 Relaxation \u0000Detecting T2 Relaxation \u0000Theoretical Model for T2 and Nanoparticle Size \u0000 \u0000 \u0000Kinetics of Magnetic Relaxation Switch Biosensors \u0000Demonstrations of Magnetic Relaxation Switch Biosensors \u0000Detecting Nucleic Acids \u0000Detecting Proteins \u0000Detecting Enzymes \u0000Detecting Viruses \u0000Detecting Small Molecules \u0000Detecting Ions \u0000Detecting Cells \u0000 \u0000 \u0000Methods Development \u0000Reagent Synthesis, Preparation, and Characterization \u0000Measurement and Sensitivity Enhancement Methods \u0000 \u0000 \u0000Micro-NMR of Magnetic Relaxation Switch Biosensors \u0000Acknowledgments \u0000 \u0000 \u0000Keywords: \u0000 \u0000nanoparticles; \u0000superparamagnetism; \u0000diagnostics; \u0000biosensor; \u0000nuclear magnetic resonance; \u0000portable detectors","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127276136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Lin, Raymond S. H. Yang, Chung-Shi Yang, Chia-Hua Lin, Louis W. Chang
{"title":"Toxicology and Biosafety Evaluations of Quantum Dots","authors":"P. Lin, Raymond S. H. Yang, Chung-Shi Yang, Chia-Hua Lin, Louis W. Chang","doi":"10.1002/9783527610419.NTLS0202","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0202","url":null,"abstract":"The sections in this article are \u0000 \u0000 \u0000Introduction \u0000The Physico-Chemical Properties of Quantum Dots \u0000Surface Chemistry and Coatings \u0000Charge and Size of QDs in Relationship to Potential Toxicity \u0000Core Metals and Biodegradation of QDs \u0000 \u0000 \u0000Toxicity and Role of Oxidative Stress \u0000ADME and Biosafety Evaluation \u0000The Mitochondrion as a Prime Target for QD Toxicity \u0000Environmental and Ecological Concerns \u0000Concluding Comments and Future Perspectives \u0000 \u0000 \u0000Keywords: \u0000 \u0000toxicity; \u0000biosafety; \u0000oxidative stress; \u0000mitochondria; \u0000cytotoxicity; \u0000pharmacokinetics; \u0000ADME","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"105 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127154869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Polymer Thin Films for Biomedical Applications","authors":"V. K. Vendra, Lin Wu, S. Krishnan","doi":"10.1002/9783527610419.NTLS0179","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0179","url":null,"abstract":"The sections in this article are \u0000 \u0000 \u0000Introduction \u0000Biocompatible Coatings \u0000Protein-Repellant Coatings \u0000PEGylated Thin Films \u0000Non-PEGylated Hydrophilic Thin Films \u0000Thin Films of Hyperbranched Polymers \u0000Multilayer Thin Films \u0000 \u0000 \u0000Antithrombogenic Coatings \u0000Surface Chemistry and Blood Compatibility \u0000Membrane-Mimetic Thin Films \u0000Heparin-Mimetic Thin Films \u0000Clot-Lyzing Thin Films \u0000Polyelectrolyte Multilayer Thin Films \u0000Polyurethane Coatings \u0000Vapor-Deposited Thin Films \u0000 \u0000 \u0000Antimicrobial Coatings \u0000Cationic Polymers \u0000Nanocomposite Polymer Thin Films Incorporating Inorganic Biocides \u0000Antibiotic-Conjugated Polymer Thin Films \u0000Biomimetic Antibacterial Coatings \u0000Thin Films Resistant to the Adhesion of Viable Bacteria \u0000 \u0000 \u0000 \u0000 \u0000Coatings for Tissue Engineering Substrates \u0000PEGylated Thin Films \u0000Zwitterionic Thin Films \u0000Thin Films of Hyperbranched Polymers \u0000Polyurethane Coatings \u0000Polysaccharide-Based Thin Films \u0000Polyelectrolyte Multilayer Thin Films \u0000Temperature-Responsive Polymer Coatings \u0000Electroactive Thin Films \u0000Other Functional Polymer Coatings \u0000Multilayer Thin Films for Cell Encapsulation \u0000Patterned Thin Films \u0000 \u0000 \u0000Polymer Thin Films for Drug Delivery \u0000Polymer Thin Films for Gene Delivery \u0000Conclusions \u0000 \u0000 \u0000Keywords: \u0000 \u0000biomaterials; \u0000biocompatible; \u0000antithrombogenic; \u0000antibacterial coatings; \u0000tissue engineering substrates; \u0000cell encapsulation; \u0000drug and gene delivery; \u0000protein-repellant surfaces; \u0000polyelectrolyte multilayers","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"191 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126421379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Structural Characterization Techniques of Molecular Aggregates, Polymer, and Nanoparticle Films","authors":"T. Hasegawa","doi":"10.1002/9783527610419.NTLS0190","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0190","url":null,"abstract":"The sections in this article are \u0000 \u0000 \u0000Introduction \u0000Characterization of Ultrathin Films of Soft Materials \u0000X-Ray Diffraction Analysis \u0000Infrared Transmission and Reflection Spectroscopy \u0000Multiple-Angle Incidence Resolution Spectrometry (MAIRS) \u0000Theoretical Background of MAIRS \u0000Molecular Orientation Analysis in Polymer Thin Films by IR-MAIRS \u0000Analysis of Metal Thin Films \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000Keywords: \u0000 \u0000polymer thin films; \u0000metal nanoparticles; \u0000multiple-angle incidence resolution spectrometry (MAIRS); \u0000infrared spectroscopy; \u0000anisotropy; \u0000plasmon-polariton","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130745335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding and controlling wetting phenomena at the micro/nanoscale","authors":"Zuankai Wang","doi":"10.1002/9783527610419.NTLS0188","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0188","url":null,"abstract":"The sections in this article are \u0000 \u0000 \u0000Introduction \u0000Wetting and Contact Angle \u0000Design and Creation of Superhydrophobic Surfaces \u0000Design Parameters for a Robust Composite Interface \u0000Creation of Superhydrophobic Surfaces \u0000Superhydrophobic Surfaces with Unitary Roughness \u0000Superhydrophobic Surfaces with Two-Scale Roughness \u0000Superhydrophobic Surfaces with Reentrant Structure \u0000 \u0000 \u0000Impact Dynamics of Water on Superhydrophobic Surfaces \u0000Impact Dynamics on Nanostructured MWNT Surfaces \u0000Impact Dynamics on Micropatterned Surfaces \u0000 \u0000 \u0000Electrically Controlled Wettability Switching on Superhydrophobic Surfaces \u0000Reversible Control of Wettability Using Electrostatic Methods \u0000Electrowetting on Superhydrophobic Surfaces \u0000Novel Strategies for Reversible Electrowetting on Rough Surfaces \u0000 \u0000 \u0000Electrochemically Controlled Wetting of Superhydrophobic Surfaces \u0000Polarity-Dependent Wetting of Nanotube Membranes \u0000Mechanism of Polarity-Dependent Wetting and Transport \u0000Potential Applications of Electrochemically Controlled Wetting and Transport \u0000 \u0000 \u0000Summary and Future Perspectives \u0000Future Perspectives \u0000 \u0000 \u0000Acknowledgments \u0000 \u0000 \u0000Keywords: \u0000 \u0000superhydrophobic; \u0000electrowetting; \u0000dewetting; \u0000carbon nanotube; \u0000contact angle; \u0000nanoengineering","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124823420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Imaging of Thin Films, and Its Application in the Life Sciences","authors":"S. Mittler","doi":"10.1002/9783527610419.NTLS0189","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0189","url":null,"abstract":"This chapter summarizes the fabrication, patterning, microscopy, and applications of thin films and, notably, their applications in the life sciences. Because the field is enormous, only organic thin films on metal and glass substrates are described. Details of optical microscopy technologies are discussed in detail, based mainly on evanescent technology, while near-field methods and electron microscopy are referred to only briefly. The applications described incorporate only a small fraction of those used in thin film technology and engineering in the life sciences. \u0000 \u0000 \u0000Keywords: \u0000 \u0000thin films; \u0000imaging; \u0000microscopy; \u0000resonant and nonresonant microscopy methods; \u0000Brewster angle; \u0000total internal reflection; \u0000surface plasmons; \u0000fluorescence","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121962356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dip‐Pen Nanolithography of Nanostructured Thin Films for the Life Sciences","authors":"E. Kim, Yuan-Shin Lee, R. Aggarwal, R. Narayan","doi":"10.1002/9783527610419.NTLS0187","DOIUrl":"https://doi.org/10.1002/9783527610419.NTLS0187","url":null,"abstract":"The sections in this article are \u0000 \u0000 \u0000Introduction \u0000Dip-Pen Nanolithography \u0000Important Parameters \u0000Applications of DPN \u0000 \u0000 \u0000Direct and Indirect Patterning of Biomaterials Using DPN \u0000Background \u0000Direct Patterning \u0000Indirect Patterning \u0000 \u0000 \u0000Applications of DPN for Medical Diagnostics and Drug Development \u0000General Methods of Nano/Micro Bioarray Patterning \u0000Virus Array Generation and Detection Tests \u0000Diagnosis of Allergic Disease \u0000Cancer Detection Using Nano/Micro Protein Arrays \u0000Drug Development \u0000Lab-on-a-Chip Using Microarrays \u0000 \u0000 \u0000Summary and Future Directions \u0000 \u0000 \u0000Keywords: \u0000 \u0000dip-pen nanolithography; \u0000protein patterning; \u0000microarray; \u0000nanoarray; \u0000medical diagnostics; \u0000drug development","PeriodicalId":312946,"journal":{"name":"Nanotechnologies for the Life Sciences","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115311197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}