Exclusive Real World Evidence Journal最新文献_第2页

Prognostic Value of Coronary Artery Calcium in the Intermediate-Risk Population of Developing Coronary Artery Disease 冠状动脉钙对冠状动脉疾病中危人群的预后价值

Exclusive Real World Evidence Journal Pub Date : 2023-11-20 DOI: 10.54136/erwej-0304-10063

K. Kagita, Madhuri Posina

{"title":"Prognostic Value of Coronary Artery Calcium in the Intermediate-Risk Population of Developing Coronary Artery Disease","authors":"K. Kagita, Madhuri Posina","doi":"10.54136/erwej-0304-10063","DOIUrl":"https://doi.org/10.54136/erwej-0304-10063","url":null,"abstract":"Background: The present study was designed to estimate the coronary artery calcium score (CACS) and its association with the incidence of major adverse cardiovascular events (MACE) in asymptomatic patients who are at risk of coronary artery disease (CAD). Objective: To estimate the CACS and its association with the incidence of MACE in asymptomatic patients. Methods: In this prospective cross-sectional observational study, 108 consecutive patients were enrolled. Demographic details and clinical data including lipid profile, systolic blood pressure, electrocardiography, 2D echocardiography, and routine blood investigations were reported. CACS was derived from computed tomography using a 256-slice scanner with a rotation time of 270 milliseconds. MACE was recorded at a one-year follow-up. Results: The mean age was 54.55 ± 7.7 years with male predominance (62%). CACS categories 0, 1-99, 10-399, 400-999, and more than 1000 constituted 43.5%, 28.7%, 18.52%, 8.33%, and 0.93% respectively. The correlation between the groups of positive and negative CACS and the presence or absence of standard risk factors was found to be statistically significant in diabetes mellitus (P=<0.001), hypertension (P=<0.001), and history of CAD in the family (P = 0.036). Although the association between smokers and calcium was statistically insignificant, it had clinical significance (P= 0.294). Out of 108 patients, MACE was observed in 16 (14.81%) patients with positive CACS at the 1-year follow-up. Conclusion:CACS measurement is often regarded as the primary non-invasive approach for risk stratification, MACE estimation, and promptly identifying high-risk asymptomatic individuals. Keywords: Coronary Artery Calcium Score; Cardiovascular Events; Coronary Calcification; Risk Stratificationa","PeriodicalId":312076,"journal":{"name":"Exclusive Real World Evidence Journal","volume":"303 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139255631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Climate Change and Disease Emergence 气候变化与疾病出现

Exclusive Real World Evidence Journal Pub Date : 2023-08-20 DOI: 10.54136/erwej-0303-10055

Gifty Immanuel

引用次数: 0

A Case of Left Atrial Myxoma Diagnosed on Routine Preoperative Evaluation 术前常规检查诊断左心房黏液瘤1例

Exclusive Real World Evidence Journal Pub Date : 2023-08-20 DOI: 10.54136/erwej-0303-10060

Dhinakaran Krishnamurthy

引用次数: 0

Bladder Endometriosis in Perimenopausal Woman- A Rare Case Report 围绝经期妇女膀胱子宫内膜异位症1例报告

Exclusive Real World Evidence Journal Pub Date : 2023-08-20 DOI: 10.54136/erwej-0303-10057

Ramya Vandanasetti, Sirisha Sunkavalli, T. Sundari, U. Devi

引用次数: 0

Tooth Fracture in a 12-year-old Patient: A Case Report 12岁患者牙齿骨折1例报告

Exclusive Real World Evidence Journal Pub Date : 2023-08-20 DOI: 10.54136/erwej-0303-10058

Suhani Gupta

引用次数: 0

Tetrapartition of the Achilles Tendon After Extensive Muscular Resection in a Lower Leg Synovial Sarcoma 下肢滑膜肉瘤广泛肌肉切除后跟腱四分离

Exclusive Real World Evidence Journal Pub Date : 2023-08-20 DOI: 10.54136/erwej-0303-10059

Antonio Gentil da Silva Martins

引用次数: 0

Perineal Hernia in a Previously Operated Patient of Prolapse: A Case Report 会阴疝术前脱垂患者一例报告

Exclusive Real World Evidence Journal Pub Date : 2023-08-20 DOI: 10.54136/erwej-0303-10061

Namrata Sethi, Anshumala Shukla-Kulkarni

{"title":"Perineal Hernia in a Previously Operated Patient of Prolapse: A Case Report","authors":"Namrata Sethi, Anshumala Shukla-Kulkarni","doi":"10.54136/erwej-0303-10061","DOIUrl":"https://doi.org/10.54136/erwej-0303-10061","url":null,"abstract":"Perineal hernia can occur in patients after abdominal or pelvic surgeries, especially in those who are immunosuppressed, have a history of laparoscopy, or are of the female sex. Patients with a perineal hernia may be asymptomatic or complain of urinary or bowel disturbance or pain. Our patient was a 63-year-old symptomatic female with a history of vaginal hysterectomy and laparoscopic sacrospinous fixation. She presented with heaviness in the lower abdomen and increased stooling frequency. She was found to have a perineal hernia up to the right ischioanal fossa, with grade four vaginal vault prolapse. Laparoscopic sacrocolpopexy with levator ani plication with perineal hernia repair was performed. We used a T-shaped mesh composed of monofilament polypropylene with a combination of synthetic sutures to plicate the levator ani bilaterally and repair the vault prolapse. The postoperative course has been favorable. As of 12 months postoperative, there are no fresh complaints. The use of mesh (e.g., polypropylene) is important for levator ani repair for reinforcement. Laparoscopic repair is generally preferred, as it provides better access with a lesser risk of complication. Almost all cases of perineal hernia in literature have been after colorectal surgery and with no specific protocol for management. A standardized surgical approach with a scope for individualization would be helpful.","PeriodicalId":312076,"journal":{"name":"Exclusive Real World Evidence Journal","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115401975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study to Determine Correlation of Elevated Serum Creatine Kinase-Muscle Brain Fraction (CK-MB) and Lactate Dehydrogenase (LDH) Levels with Asphyxia Neonatorum and Severity of Hypoxic Ischaemic Encephalopathy 血清肌酸激酶-肌脑分数(CK-MB)和乳酸脱氢酶(LDH)水平升高与新生儿窒息和缺氧缺血性脑病严重程度的相关性研究

Exclusive Real World Evidence Journal Pub Date : 2023-08-20 DOI: 10.54136/erwej-0303-10056

N. Shaikh, Namey Sujata, Sudhir Sarwade

{"title":"Study to Determine Correlation of Elevated Serum Creatine Kinase-Muscle Brain Fraction (CK-MB) and Lactate Dehydrogenase (LDH) Levels with Asphyxia Neonatorum and Severity of Hypoxic Ischaemic Encephalopathy","authors":"N. Shaikh, Namey Sujata, Sudhir Sarwade","doi":"10.54136/erwej-0303-10056","DOIUrl":"https://doi.org/10.54136/erwej-0303-10056","url":null,"abstract":"Background: Asphyxia Neonatorum is a significant contributor to neonatal mortality and morbidity. Its burden in resource-poor countries prompts the development of investigative modalities that offers accuracy and affordability. Objective: To determine that serum CK-MB and LDH estimation could be markers of Asphyxia neonatorum, and the elevated levels directly correlate with the grade of severity of Hypoxic Ischemic Encephalopathy (HIE) as defined by Levine. Methods: In this single-center, non-interventional study, we included 100 asphyxiated neonates from level III NICU in the case group, and 100 apparently healthy neonates from the post-natal ward admitted over 18 months at RCSM Government Medical College and CPR Hospital, Kolhapur. 100 healthy neonates were the control group. Results: The median 8-hr serum CK-MB in the case group was 74 U/L and in the control group as 63.5 U/L with P<0.001. Whereas the median serum LDH level in the case group was 597 U/L and the control group was 383.5 U/L with P<0.001. Raised LDH (cut off 580 U/L) had 100% specificity, while CK-MB (cut off 92.6 U/L) had 100% specificity for asphyxia. Amongst the neonates with HIE (n=60), 56% had raised CK-MB (cut off 92.6) and 80% had raised LDH (cut off 580 U/L). 100% of neonates with HIE Grade III (n=9) had elevated CK-MB and LDH levels. Conclusion: The present study concluded that CK-MB and LDH as biochemical markers can be utilitarian in the diagnosis of perinatal asphyxia.","PeriodicalId":312076,"journal":{"name":"Exclusive Real World Evidence Journal","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127157366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uterine Rupture from Previous Myomectomy Scar 子宫肌瘤切除术后瘢痕性子宫破裂

Exclusive Real World Evidence Journal Pub Date : 2023-05-20 DOI: 10.54136/erwej-0302-10054

Shruti Haldar, Indrani Haldar

引用次数: 0

Congenital Macrostomia: A Rare Congenital Anomaly 先天性大口畸形:一种罕见的先天性异常

Exclusive Real World Evidence Journal Pub Date : 2023-05-20 DOI: 10.54136/erwej-0302-10053

Varsha Deodhe, Ravindra Sonawane, R. Koppikar

引用次数: 0