Environmental Pollution最新文献

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Formation and stability of environmental persistent free radicals (EPFRs) from the reaction between phenolic compounds and Fe(III)-loaded particles 酚类化合物与载铁颗粒反应中环境持久性自由基(EPFRs)的形成和稳定性
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-19 DOI: 10.1016/j.envpol.2025.127012
Yuxuan Cao , Tianyi Zhao , Xiaoyu Hu , Juanjuan Qin , Qinghe Cai , Yang Bai , Lijia Zhang , Peng Huo , Yang Zhang
{"title":"Formation and stability of environmental persistent free radicals (EPFRs) from the reaction between phenolic compounds and Fe(III)-loaded particles","authors":"Yuxuan Cao ,&nbsp;Tianyi Zhao ,&nbsp;Xiaoyu Hu ,&nbsp;Juanjuan Qin ,&nbsp;Qinghe Cai ,&nbsp;Yang Bai ,&nbsp;Lijia Zhang ,&nbsp;Peng Huo ,&nbsp;Yang Zhang","doi":"10.1016/j.envpol.2025.127012","DOIUrl":"10.1016/j.envpol.2025.127012","url":null,"abstract":"<div><div>Environmentally Persistent Free Radicals (EPFRs) are defined as a new type of pollutant, which can cause environmental pollution and do harm to human health. However, few studies have comprehensively explored the formation conditions and mechanism of EPFRs. This study investigated the EPFR formation abilities and mechanisms of two organic phenolic precursors (4-tert-butylcatechol, TBC, and catechol, CT) on model particulate matter (Fe(III)-loaded SiO<sub>2</sub> and kaolin) using electron paramagnetic resonance (EPR) in combination with Fourier-transform infrared attenuated total-reflectance spectroscopy (FTIR-ATR) and Gas Chromatography-Mass Spectrometry (GC-MS) techniques. The results showed that TBC produces more EPFRs than CT, while the matrix kaolin produces a wider linewidth and greater concentration of EPFRs compared to SiO<sub>2</sub>. The increasing concentrations of organic phenolic compounds led to a decrease in the species of EPFRs but an increase in their concentration. The variation of EPFR formation from CT and TBC was evaluated through long-term observation. The results revealed that CT could cause a stable increase in EPFR formation during the 456 h, whereas a reverse trend was observed for TBC. The predominant final products of dimers for both precursors indicated that EPFRs might have been intermediate products via polymerization reaction. This study suggests that when predicting the environmental behavior and risks of EPFRs, it is important to consider (1) the chemical properties of the particulate matter and (2) the precursor species and concentration.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"Article 127012"},"PeriodicalIF":7.3,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144887180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ferroptosis-driven neurobehavioral impairment in zebrafish embryos: Mechanistic links to developmental dibutyl phthalate exposure. 斑马鱼胚胎中铁中毒导致的神经行为损伤:与发育中邻苯二甲酸二丁酯暴露的机制联系。
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-19 DOI: 10.1016/j.envpol.2025.127009
Tingting Hou, Yuhang Guo, Lu Tao, Xiaoteng Fan
{"title":"Ferroptosis-driven neurobehavioral impairment in zebrafish embryos: Mechanistic links to developmental dibutyl phthalate exposure.","authors":"Tingting Hou, Yuhang Guo, Lu Tao, Xiaoteng Fan","doi":"10.1016/j.envpol.2025.127009","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.127009","url":null,"abstract":"<p><p>Dibutyl phthalate (DBP), a ubiquitous chemical contaminant detected in various environmental matrices, poses growing concerns regarding its ecotoxicity and public health risks. In this study, zebrafish (Danio rerio) model was used to investigate the ferroptosis-mediated neurotoxicity elicited by iron dyshomeostasis and lipid peroxidation, upon developmental DBP exposure. DBP-induced ferroptosis compromised zebrafish embryogenesis, leading to reduced tail bent rate and heart rate, as well as elevated mortality and deformity. Larval neurobehavioral deficits, assessed through spontaneous locomotion, light/dark transition, and vibrational startle response assays, manifested as significant hypoactivity in total distance, velocity, maximum acceleration, and cumulative mobility. Importantly, these impairments were notably attenuated by the iron chelator of deferasirox. Metabolomic profiling revealed profound perturbations in the signaling pathway of Neuroactive ligand-receptor interaction, as indicated by KEGG enrichment analyses. Consistently, neurotransmitter levels (serotonin, dopamine, taurine, acetylcholine) and transcriptional markers related to neurodevelopment were suppressed by DBP, but differentially restored upon co-treatment with deferasirox. These mechanistic findings bridge environmental ecotoxicology with vertebrate developmental risk prediction, underscoring the urgency of developing potential management and intervention strategies to address phthalates exposure during critical developmental windows.</p>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"127009"},"PeriodicalIF":7.3,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144937765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of biomass burning on HONO chemistry and atmospheric oxidation capacity in the Yangtze River delta, China 生物质燃烧对长江三角洲HONO化学和大气氧化能力的影响
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-19 DOI: 10.1016/j.envpol.2025.127008
Baobin Han , Min Qin , Wu Fang , Fanhao Meng , Ke Tang , Yihang Yu , Song Guo , Keding Lu , Pinhua Xie
{"title":"Impact of biomass burning on HONO chemistry and atmospheric oxidation capacity in the Yangtze River delta, China","authors":"Baobin Han ,&nbsp;Min Qin ,&nbsp;Wu Fang ,&nbsp;Fanhao Meng ,&nbsp;Ke Tang ,&nbsp;Yihang Yu ,&nbsp;Song Guo ,&nbsp;Keding Lu ,&nbsp;Pinhua Xie","doi":"10.1016/j.envpol.2025.127008","DOIUrl":"10.1016/j.envpol.2025.127008","url":null,"abstract":"<div><div>Extensive research confirms that biomass burning (BB) significantly contributes to particulate matter and gaseous pollutant emissions. Open burning of wheat straw is particularly common during the harvest season, directly affecting air quality and atmospheric oxidation capacity. In this study, nitrous acid (HONO) and associated atmospheric species were investigated during the BB season at a suburban station, as part of the 2018 EXPLORE-YRD campaign. Based on the enhancement ratio of acetonitrile (C<sub>2</sub>H<sub>3</sub>N) to CO, 10 nighttime BB events were identified, with the remaining nighttime periods defined as non-biomass burning (NBB) periods. Compared to the NBB period, the HONO levels during BB events increased from 0.49 ± 0.48 ppbv to 1.75 ± 0.98 ppbv. The average concentrations of other species also exhibited significant increases, ranging from 73 % to 192 %. The average HONO to CO normalized excess mixing ratio (NEMR) in the BB events ranged from 1.83 ± 0.42 to 3.41 ± 0.39 ppbv/ppmv, consistent with the range reported in previous laboratory and field burning studies. Smoldering combustion may contribute to the lower observed HONO to CO NEMR. Furthermore, the roles of different heterogeneous sources in HONO production were compared using correlation analysis and source strength calculations. The ground surface displayed significantly greater promotion of NO<sub>2</sub> to HONO conversion than the aerosol surface during NBB periods. During BB periods, the significant increase in particle concentration and expanded aerosol surface area result in the contribution of aerosol surface being comparable to that of the ground surface. The NO<sub>2</sub> heterogeneous conversion to HONO was influenced by relative humidity during nighttime. Following the BB events, HONO photolysis (1.76 ± 0.69 ppbv h<sup>−1</sup>) emerged as the primary hydroxyl radical (OH) source, exceeding contributions from formaldehyde photolysis (0.86 ± 0.36 ppbv h<sup>−1</sup>) and O<sub>3</sub> photolysis (0.49 ± 0.32 ppbv h<sup>−1</sup>).</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"Article 127008"},"PeriodicalIF":7.3,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144879777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on “Direct laser infrared microscopy for the monitoring of microplastics in Holothuria poli and sediments of the Mar Menor coastal lagoon” 对“直接激光红外显微法监测马尔门诺尔海岸泻湖海螺和沉积物中的微塑料”一文的评论
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-18 DOI: 10.1016/j.envpol.2025.127006
Prajnasini Satapathy , Rachana Mehta , Ranjana Sah
{"title":"Comment on “Direct laser infrared microscopy for the monitoring of microplastics in Holothuria poli and sediments of the Mar Menor coastal lagoon”","authors":"Prajnasini Satapathy ,&nbsp;Rachana Mehta ,&nbsp;Ranjana Sah","doi":"10.1016/j.envpol.2025.127006","DOIUrl":"10.1016/j.envpol.2025.127006","url":null,"abstract":"","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"Article 127006"},"PeriodicalIF":7.3,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144889427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microplastic accumulation in endometrial cancer tissues and its metabolic impact 子宫内膜癌组织中的微塑料积累及其代谢影响
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-18 DOI: 10.1016/j.envpol.2025.127005
Chunlin Dong , Hongwen Xu , Bing Zhang , Yaying Lin , Jing Song , Jinjin Yu , Ding Ma
{"title":"Microplastic accumulation in endometrial cancer tissues and its metabolic impact","authors":"Chunlin Dong ,&nbsp;Hongwen Xu ,&nbsp;Bing Zhang ,&nbsp;Yaying Lin ,&nbsp;Jing Song ,&nbsp;Jinjin Yu ,&nbsp;Ding Ma","doi":"10.1016/j.envpol.2025.127005","DOIUrl":"10.1016/j.envpol.2025.127005","url":null,"abstract":"<div><div>With increasing global awareness of plastic pollution, microplastics (MPs) have emerged as a potential environmental health hazard. While MPs have been detected in various human tissues, their relevance to gynecological malignancies, particularly endometrial cancer (EC), remains largely unexplored. This study aims to evaluate MP accumulation in EC tissues and investigate its potential impact on tissue metabolic reprogramming. Raman spectroscopy, combined with untargeted metabolomics, was employed to comprehensively assess both the presence and metabolic consequences of MPs in EC and matched normal endometrial tissues. In 32 analyzed samples, MPs averaged 3.2 ± 2.3 particles/g, with polyethylene (15.7 %), polypropylene (11.8 %), ethylene-acrylic acid (10.8 %), and polystyrene (8.8 %) predominating. Endometrial cancer tissues exhibited significantly higher MP levels (3.7 ± 2.5 particles/g) than normal controls (2.0 ± 1.5 particles/g). Metabolomic profiling revealed that MP exposure is associated with substantial alterations in cancer-related metabolic pathways, with the glycine, serine, and threonine metabolism pathway showing the most pronounced enrichment. Key differential metabolites included glycine, N-acetyl-arginine, and 4-aminobutyric acid, which have been implicated in tumor proliferation and immune regulation. These findings suggest that MPs may promote the development of EC through modulation of metabolic pathways, providing novel insights into the role of MPs in gynecological cancers. This study highlights the emerging threat of environmental pollution to women's reproductive health and offers innovative theoretical perspectives for future research.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"Article 127005"},"PeriodicalIF":7.3,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144879048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Where there is smoke, there is fire: long- and mid-range biomass burning role on São Paulo's state air quality 哪里有烟,哪里就有火:长期和中期生物质燃烧对<s:1>圣保罗州空气质量的影响
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-18 DOI: 10.1016/j.envpol.2025.126993
Anderson Paulo Rudke , Leila Droprinchinski Martins , Jorge Alberto Martins , Maurício C. Mantoani , Maria de Fátima Andrade , Prashant Kumar , Ronaldo Adriano Alves , Rizzieri Pedruzzi , Tammy Thompson , Otavio Medeiros Sobrinho , Bruna Lima Véras Maia , Amanda Karine Chaves Ribeiro , Taciana Toledo de Almeida Albuquerque
{"title":"Where there is smoke, there is fire: long- and mid-range biomass burning role on São Paulo's state air quality","authors":"Anderson Paulo Rudke ,&nbsp;Leila Droprinchinski Martins ,&nbsp;Jorge Alberto Martins ,&nbsp;Maurício C. Mantoani ,&nbsp;Maria de Fátima Andrade ,&nbsp;Prashant Kumar ,&nbsp;Ronaldo Adriano Alves ,&nbsp;Rizzieri Pedruzzi ,&nbsp;Tammy Thompson ,&nbsp;Otavio Medeiros Sobrinho ,&nbsp;Bruna Lima Véras Maia ,&nbsp;Amanda Karine Chaves Ribeiro ,&nbsp;Taciana Toledo de Almeida Albuquerque","doi":"10.1016/j.envpol.2025.126993","DOIUrl":"10.1016/j.envpol.2025.126993","url":null,"abstract":"<div><div>Prolonged exposure to fine particulate matter (PM<sub>2.5</sub>) is the leading environmental risk factor for human health. In Brazil, frequent wildfires during dry seasons, especially in the Amazon, Cerrado, and more recently the Pantanal, significantly increase PM<sub>2.5</sub> levels, often exceeding national and international air quality standards. This study analyzed ten years of PM<sub>2.5</sub> data from 25 monitoring stations across São Paulo State and used 1464 backward trajectories from the HYSPLIT model to assess the influence of open biomass burning and long-range pollutant transport. Results show that after declining trends, 2024 recorded a sharp increase in PM<sub>2.5</sub>, with concentrations peaking up to seven times higher during fire season and some daily averages exceeding 100 μg/m<sup>3</sup>. The analysis revealed that air masses arriving in the state frequently crossed major fire hotspots, including neighboring states and countries. Consequently, the estimated avoidable deaths rose significantly in 2024, with interior municipalities showing the highest rates. These findings underscore the urgent need to address transboundary pollution sources linked to open biomass burning within Brazil's air quality management and climate adaptation strategies.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"Article 126993"},"PeriodicalIF":7.3,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144864824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tire wear particles drive size-dependent loss of freshwater bacterial biofilm diversity 轮胎磨损颗粒驱动淡水细菌生物膜多样性的大小依赖性损失
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-16 DOI: 10.1016/j.envpol.2025.127004
Dana Bludau , Sophie Volkenandt , Julian Wagenhofer , Frank Nitsche , Jens Boenigk
{"title":"Tire wear particles drive size-dependent loss of freshwater bacterial biofilm diversity","authors":"Dana Bludau ,&nbsp;Sophie Volkenandt ,&nbsp;Julian Wagenhofer ,&nbsp;Frank Nitsche ,&nbsp;Jens Boenigk","doi":"10.1016/j.envpol.2025.127004","DOIUrl":"10.1016/j.envpol.2025.127004","url":null,"abstract":"<div><div>Tire wear particles (TWPs) represent a significant, yet understudied, source of anthropogenic pollution in aquatic environments, contributing to microplastic contamination and potentially altering microbial ecosystems. As TWPs are continuously released through abrasion during vehicle use, they accumulate in rivers and sediments, where they can act as surfaces for microbial biofilm formation. In this study, we investigated how TWP characteristics - particle size (small &amp; large), wear condition (unused &amp; used), and vehicle type (car &amp; truck) - affect microbial biofilm composition after four weeks of exposure in the River Rhine, compared to natural sediment. Using 16S rRNA amplicon sequencing, we found that TWP-associated biofilms harboured significantly lower bacterial diversity than natural sediment biofilms. While a substantial number of OTUs were shared between both habitats, TWPs exhibited increased richness but decreased overall diversity, indicating selective enrichment of specialized taxa. Larger particles further reduced diversity, and specific genera such as <em>Aquabacterium</em> and <em>Ketobacter</em> were highly enriched on TWPs, indicating selective microbial colonization. These findings reveal the effects of TWPs on microbial biofilm communities, emphasizing their potential role in altering freshwater microbial ecosystems. Given the widespread release of TWPs, understanding their ecological impact is crucial for assessing their role in aquatic pollution and ecosystem functioning.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"Article 127004"},"PeriodicalIF":7.3,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144861144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of BPAF Exposure on Endometrial Remodeling: A Focus on The Homeostasis of The Extracellular Matrix and The Immune Status BPAF暴露对子宫内膜重塑的影响:关注细胞外基质的稳态和免疫状态
IF 8.9 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-16 DOI: 10.1016/j.envpol.2025.127000
Xiaotong Ji, Jiande Li, Peilin Li, Linzhuo Shen, Haoyang Wu, Weiwei Wang, Lihong Su, Zhihong Zhang
{"title":"Effects of BPAF Exposure on Endometrial Remodeling: A Focus on The Homeostasis of The Extracellular Matrix and The Immune Status","authors":"Xiaotong Ji, Jiande Li, Peilin Li, Linzhuo Shen, Haoyang Wu, Weiwei Wang, Lihong Su, Zhihong Zhang","doi":"10.1016/j.envpol.2025.127000","DOIUrl":"https://doi.org/10.1016/j.envpol.2025.127000","url":null,"abstract":"Bisphenol AF (BPAF), a substitute for bisphenol A (BPA), is frequently found in the environment and daily necessities and has garnered significant attention due to its endocrine-disrupting effects. Uterus is a potential target of BPA while more evidences about BPAF are needed, especially at human-relevant levels. The aim of this study was to determine the effects of BPAF exposure with realistic human exposure pathway and dosage on the uterus, as well as to explore its molecular mechanisms through transcriptome sequencing (RNA-seq) and alternative splicing (AS) analysis. Female CD-1 mice were continuously exposed to BPAF levels of 30, 300, and 3000 μg/kg/day for six weeks through diet. Following euthanasia, blood and uterus were collected. The results showed that mice in BPAF exposure group exhibited symptoms of endometrial hyperplasia in the uterus, characterized by thickening of the endometrium. In addition, BPAF exposure altered the levels of nine hormones, including pregnenolone, androsterone, estrone, testosterone and so on, and led to prolonged estrus cycle. Transcriptomic analysis revealed a significant disruption in the balance of extracellular matrix (ECM) and humoral immune biological processes, to which matrix metallopeptidase 7 (<em>Mmp7</em>) and indian hedgehog (<em>Ihh</em>) were identified as key genes related. Additionally, AS analysis indicated intron retention occurred in collagen type I alpha 2 chain (<em>Col1a2</em>), which resulted in a protein structure alternation and further led to uterine abnormality. These findings suggest that BPAF exposure at relatively low levels disturbs the balance of the extracellular matrix and the immune system in the uterus. Considering that there are currently only toxicity limits for BPA, our study provides data reference for the toxicological evaluation and threshold setting of BPA substitute, and provides a new research paradigm for the progress of related toxicology research.","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"13 1","pages":""},"PeriodicalIF":8.9,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microplastics in aquatic communities of neotropical agroecosystems 新热带农业生态系统水生群落中的微塑料。
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-16 DOI: 10.1016/j.envpol.2025.126997
Taciéli dos Santos , Angelo R. Morrone , Ricardo Meurer Papaleo , Daniela Alves da Silva , Fabrício Luiz Skupien , Liziara da Costa Cabrera , David Augusto Reynalte-Tataje
{"title":"Microplastics in aquatic communities of neotropical agroecosystems","authors":"Taciéli dos Santos ,&nbsp;Angelo R. Morrone ,&nbsp;Ricardo Meurer Papaleo ,&nbsp;Daniela Alves da Silva ,&nbsp;Fabrício Luiz Skupien ,&nbsp;Liziara da Costa Cabrera ,&nbsp;David Augusto Reynalte-Tataje","doi":"10.1016/j.envpol.2025.126997","DOIUrl":"10.1016/j.envpol.2025.126997","url":null,"abstract":"<div><div>Microplastics (MP's) are pervasive pollutants; however, research on their ingestion by freshwater biota in the Neotropics remains limited, particularly in riverine ecosystems surrounded by agricultural landscapes. This study tested the hypothesis that MP's are present in streams within agricultural areas and that MP's loads in aquatic organisms can be predicted based on stream position and both taxonomic and ecological traits. Macroinvertebrates and fish were sampled at 18 sites across six streams, covering upper, middle, and lower reaches within the Comandaí basin (Brazil) during the winter and spring of 2022. Both macroinvertebrate and fish taxa with diverse ecological traits were selected within a broad range for MP's analysis. Fish body length and weight were measured to assess potential correlations with MP's loads. MP's were detected in organisms from all sampling sites. In total, 106 plastic particles were recovered from macroinvertebrates and 172 from fish. Most particles were blue/green polyethylene fibers. In fish, MP's presence was associated with specific trophic guilds, water column position, and taxa, whereas MP's loads in macroinvertebrates were consistent across taxa and trophic guilds. These findings highlight the vulnerability of freshwater organisms to plastic pollution throughout stream systems with certain fish groups exhibiting greater susceptibility to MP's ingestion.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"Article 126997"},"PeriodicalIF":7.3,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genome-wide alterations of DNA methylation and hydroxymethylation in uroepithelial cells revealed potential carcinogenicity of halobenzoquinone disinfection byproducts 尿上皮细胞DNA甲基化和羟甲基化的全基因组改变揭示了卤苯醌消毒副产物的潜在致癌性
IF 7.3 2区 环境科学与生态学
Environmental Pollution Pub Date : 2025-08-16 DOI: 10.1016/j.envpol.2025.127001
Xinran Zhao , Mine Du , Pei Guo , Jiating Zhao , Lizhong Zhu , Wei Wang
{"title":"Genome-wide alterations of DNA methylation and hydroxymethylation in uroepithelial cells revealed potential carcinogenicity of halobenzoquinone disinfection byproducts","authors":"Xinran Zhao ,&nbsp;Mine Du ,&nbsp;Pei Guo ,&nbsp;Jiating Zhao ,&nbsp;Lizhong Zhu ,&nbsp;Wei Wang","doi":"10.1016/j.envpol.2025.127001","DOIUrl":"10.1016/j.envpol.2025.127001","url":null,"abstract":"<div><div>Halobenzoquinones (HBQs), a class of emerging disinfection byproducts (DBPs) ubiquitously existed in drinking water, were predicted to be bladder carcinogens. HBQs exhibited a unique capacity to promote the conversion of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC). Thus, we propose that a varied epigenetic landscape may serve as an essential initial molecular event in cancer development under HBQs stress. We investigated the global levels of cytosine modifications and revealed genome-wide alteration of 5mC and 5hmC induced by HBQs in human bladder epithelial cells SV-HUC-1. The results showed that the global level of 5hmC significantly increased after exposure to HBQs. HBQ exposure resulted in more hypo-methylated (39,365) and hyper-hydroxymethylated (26,053) sites, with 7441 overlapping sites, suggesting the conversion of 5mC to 5hmC. The genes associated with hypo-differentially methylated regions (hypo-DMRs) and hyper-differentially hydroxymethylated regions (hyper-DhMRs) were enriched in cancer-related pathways, such as the Hippo signaling pathway, PI3K-AKT signaling pathway and Wnt signaling pathway. In particular, three bladder cancer-related genes (<em>CASC8</em>, <em>TTTY14</em>, <em>METRNL</em>) associated with hypo-DMRs or hyper-DhMRs exhibited significantly differential expression. This study revealed epigenetic changes induced by HBQs and a potential association with the risk of bladder cancer.</div></div>","PeriodicalId":311,"journal":{"name":"Environmental Pollution","volume":"384 ","pages":"Article 127001"},"PeriodicalIF":7.3,"publicationDate":"2025-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144857924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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