Environment International最新文献

{"title":"Hazard assessment of airborne and foodborne biodegradable polyhydroxyalkanoates microplastics and non-biodegradable polypropylene microplastics","authors":"Hua Zha ,&nbsp;Shengjie Li ,&nbsp;Aoxiang Zhuge ,&nbsp;Jian Shen ,&nbsp;Yuanyuan Yao ,&nbsp;Kevin Chang ,&nbsp;Lanjuan Li","doi":"10.1016/j.envint.2025.109311","DOIUrl":"10.1016/j.envint.2025.109311","url":null,"abstract":"<div><div>Microplastics (MP) are ubiquitous in the environment, and are toxic to various living organisms. Proper application of biodegradable plastics may alleviate the hazards of conventional non-biodegradable plastics. In the current study, multi-omics analyses were performed to compare the biodegradable polyhydroxyalkanoates (PHA) and non-biodegradable polypropylene (PP) MP for their toxicity on mouse liver and lung. Airborne PHA MP induced nasal microbiome dysbiosis, pulmonary microbiome alteration, pulmonary and serum metabolome disruption, and hepatic transcriptome disturbances, resulting in mild pulmonary toxicity. By contrast, airborne PP MP caused greater alterations in nasal and pulmonary microbiome, pulmonary and serum metabolome, and hepatic transcriptome, resulting in pulmonary and hepatic toxicity. Both foodborne PHA and PP MP caused intestinal microbiome dysbiosis, while foodborne PHA MP caused slighter intestinal and serum metabolome disruption, hepatic transcriptome disturbances and hepatotoxicity (e.g., lower serum aspartate aminotransferase and alanine aminotransferase) compared to foodborne PP MP. Some potential differential biomarkers were determined between PP and PHA MP exposures, i.e., nasal <em>Allobaculum</em> and pulmonary <em>Alloprevotella</em> for airborne PHA; nasal <em>Lactobacillus</em> and pulmonary <em>Acinetobacter</em> for airborne PP; intestinal <em>Faecalibacterium</em> for foodborne PHA; and intestinal <em>unclassified_Erysipelatoclostridiaceae</em> for foodborne PP. The results show that PHA MP can induce less pulmonary and hepatic toxicity compared to PP MP, suggesting PHA is a potential substitution for PP. The findings can benefit the hazard assessment of airborne and foodborne PHA and PP MP.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109311"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143055348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of a multicomponent nature-based intervention on well-being and environmental engagement: A randomized clinical trial","authors":"Eliseth Ribeiro Leão ,&nbsp;Roberta Maria Savieto ,&nbsp;Gustavo Benvenutti Borba ,&nbsp;Elivane da Silva Victor ,&nbsp;Sabrina Bortolossi Bomfim ,&nbsp;Erika Hingst-Zaher ,&nbsp;Luciano Moreira Lima ,&nbsp;Luccas Guilherme Rodrigues Longo ,&nbsp;Leticia Bernardes de Oliveira ,&nbsp;Denise Tiemi Noguchi ,&nbsp;Lucas Pires Garcia Oliveira ,&nbsp;Rafael Facure Moredo ,&nbsp;Clarissa de Oliveira Santos ,&nbsp;André Menini ,&nbsp;Lital Moro Bass ,&nbsp;Karina Pavão Patrício ,&nbsp;Giulia Catissi ,&nbsp;João Marcos Rosa ,&nbsp;Emerson Barão Rodrigues Soldado ,&nbsp;Floriana Bertini ,&nbsp;Edgard Joseph Kiriyama","doi":"10.1016/j.envint.2025.109286","DOIUrl":"10.1016/j.envint.2025.109286","url":null,"abstract":"<div><h3>Background</h3><div>Nature-based interventions (NBIs) benefit human well-being, but clinical trials comparing different NBIs in various natural environments are scarce.</div></div><div><h3>Objective</h3><div>To evaluate the efficacy of a multicomponent nature-based intervention (MNBI) in comparison to control group (classical forest bathing). Primary outcome: well-being; Secondary outcomes: vitality, happiness, connection, and engagement with nature across urban, <em>peri</em>-urban, and rural areas.</div></div><div><h3>Methods</h3><div>Randomized clinical trial with 486 participants between October/2022 and June/2023, from five natural areas in Southeast and Southern/Brazil. Well-being was assessed immediately before the activity and 30 days after, and secondary outcomes immediately before, immediately after and 30 days after. The data analyses considered a 95 % confidence interval and p-values &lt; 0.05.</div></div><div><h3>Results</h3><div>The main hypothesis was confirmed, well-being levels of MNBI group were significantly improved, especially in <em>peri</em>-urban areas (p = 0.036). Both groups increased vitality (p &lt; 0.001), but MNBI was more effective overall (p = 0.038), especially in urban areas (p = 0.020). Happiness increased in both groups (p = 0.001), but MNBI participants maintained higher levels 30 days post-intervention (p = 0.010). Nature connection increased significantly in both groups (p &lt; 0.001) but remained higher in MNBI after 30 days (p = 0.021), especially in <em>peri</em>-urban areas (p = 0.034). While both groups reported calm and relaxation, MNBI uniquely fostered learning, knowledge, and contemplation.</div></div><div><h3>Conclusions</h3><div>MNBI was more effective than classical forest bathing in improving well-being, nature connection and pro-environmental behaviors, particularly in <em>peri</em>-urban settings, expanding the potential of NBIs for well-being promotion. ClinicalTrials registration: NCT05486156.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109286"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142989171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation-induced impacts on mitochondrial DNA and the transgenerational genomic instability","authors":"Ryosuke Seino ,&nbsp;Haruka Kubo ,&nbsp;Kai Nishikubo ,&nbsp;Hisanori Fukunaga","doi":"10.1016/j.envint.2025.109315","DOIUrl":"10.1016/j.envint.2025.109315","url":null,"abstract":"<div><h3>Background</h3><div>Mitochondrial genomes are dynamically evolving and are shaped by somatic mutation and selection throughout the female germline. In this study, we investigated the radiation-induced impacts on mitochondrial DNA <em>in vitro</em> and <em>in vivo</em>, as well as the transgenerational inheritance.</div></div><div><h3>Methods</h3><div>Human cervical cancer HeLa cells and telomerase-immortalized normal fibroblast BJ1-hTERT cells were exposed to X-rays at 0.5–8 Gy. Also, we exposed 8-week-old female C57BL/6N mice to a single whole-body dose of 2 Gy of X-rays and mated them with healthy males 1 day after irradiation. We extracted DNA from the irradiated cells, female mice, and the 2-week-old pups, then examined the mitochondrial DNA copy numbers (mtDNAcns) and radiation-induced damage by real-time quantitative PCR.</div></div><div><h3>Results</h3><div>The mtDNAcn levels in cells increased and the intact copy ratios decreased 24 h after irradiation, resulting in the delayed shift of heteroplasmy. Also, the peripheral blood-derived mtDNAcn levels in irradiated females increased 1 day after irradiation and the intact copy rates decreased, supporting the results <em>in vitro</em>. Furthermore, whole blood-derived mtDNAcn levels decreased in 2-week-old pups born from irradiated mothers, indicating the mitochondrial genomic instability.</div></div><div><h3>Discussion</h3><div>We found the delayed induction of mtDNA damage in human cancer and noncancerous cells after irradiation, as well as the same trend in mice. Furthermore, to our knowledge, this is first to demonstrate the hereditary effects of radiation on the regulation of mitochondrial genome. These provide novel insights into the significance of radiation protection and preventive medicine for not only pre-pregnancy females but also the next generation.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109315"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143072822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Climate change rivals fertilizer use in driving soil nitrous oxide emissions in the northern high latitudes: Insights from terrestrial biosphere models","authors":"Naiqing Pan ,&nbsp;Hanqin Tian ,&nbsp;Hao Shi ,&nbsp;Shufen Pan ,&nbsp;Josep G. Canadell ,&nbsp;Jinfeng Chang ,&nbsp;Philippe Ciais ,&nbsp;Eric A. Davidson ,&nbsp;Gustaf Hugelius ,&nbsp;Akihiko Ito ,&nbsp;Robert B. Jackson ,&nbsp;Fortunat Joos ,&nbsp;Sebastian Lienert ,&nbsp;Dylan B. Millet ,&nbsp;Stefan Olin ,&nbsp;Prabir K. Patra ,&nbsp;Rona L. Thompson ,&nbsp;Nicolas Vuichard ,&nbsp;Kelley C. Wells ,&nbsp;Chris Wilson ,&nbsp;Sönke Zaehle","doi":"10.1016/j.envint.2025.109297","DOIUrl":"10.1016/j.envint.2025.109297","url":null,"abstract":"<div><div>Nitrous oxide (N₂O) is the most important stratospheric ozone-depleting agent based on current emissions and the third largest contributor to increased net radiative forcing. Increases in atmospheric N₂O have been attributed primarily to enhanced soil N₂O emissions. Critically, contributions from soils in the Northern High Latitudes (NHL, &gt;50°N) remain poorly quantified despite their exposure to rapid rates of regional warming and changing hydrology due to climate change. In this study, we used an ensemble of six process-based terrestrial biosphere models (TBMs) from the Global Nitrogen/Nitrous Oxide Model Intercomparison Project (NMIP) to quantify soil N₂​O emissions across the NHL during 1861–2016. Factorial simulations were conducted to disentangle the contributions of key driving factors, including climate change, nitrogen inputs, land use change, and rising atmospheric CO₂ concentration​, to the trends in emissions. The NMIP models suggests NHL soil N₂O emissions doubled from 1861 to 2016, increasing on average by 2.0 ± 1.0 Gg N/yr (<em>p</em> &lt; 0.01). Over the entire study period, while N fertilizer application (42 ± 20 %) contributed the largest share to the increase in NHL soil emissions, climate change effect was comparable (37 ± 25 %), underscoring its significant role. In the recent decade (2007–2016), anthropogenic sources contributed 47 ± 17 % (279 ± 156 Gg N/yr) of the total N₂O emissions from the NHL, while unmanaged soils contributed a comparable amount (290 ± 142 Gg N/yr). The trend of increasing emissions from nitrogen fertilizer reversed after the 1980 s because of reduced applications in non-permafrost regions. In addition, increased plant growth due to CO₂ fertilization suppressed simulated emissions. However, permafrost soil N₂O emissions continued increasing attributable to climate warming; the interaction of climate warming and increasing CO₂ concentrations on nitrogen and carbon cycling will determine future trends in NHL soil N₂O emissions. The rigorous interplay between process modeling and field experimentation will be essential for improving model representations of the mechanisms controlling N₂O fluxes in the Northern High Latitudes and for reducing associated uncertainties.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109297"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastics in human skeletal tissues: Presence, distribution and health implications","authors":"Qiaoyi Yang ,&nbsp;Ye Peng ,&nbsp;Xiaodong Wu ,&nbsp;Xiaorui Cao ,&nbsp;Peng Zhang ,&nbsp;Zhuowen Liang ,&nbsp;Jiawei Zhang ,&nbsp;Yongfeng Zhang ,&nbsp;Peipei Gao ,&nbsp;Yunfang Fu ,&nbsp;Peng Liu ,&nbsp;Zipeng Cao ,&nbsp;Tan Ding","doi":"10.1016/j.envint.2025.109316","DOIUrl":"10.1016/j.envint.2025.109316","url":null,"abstract":"<div><div>Although microplastics have been detected in human blood, placenta and other tissues. In this study, for the first time, we characterized the presence and variation of microplastic deposition patterns in three human skeletal tissues, namely the bone, cartilage, and intervertebral discs. Forty microplastic fragments were observed in 24 samples from the bone, cartilage, and intervertebral disc, ranging from 25.44 to 407.39 μm in diameter. The deposition abundance of microplastics in the human intervertebral disc (61.1 ± 44.2 particles/g) was higher than those in the bone (22.9 ± 15.7 particles/g) and cartilage tissue (26.4 ± 17.6 particles/g). The average sizes of microplastics in intervertebral discs (159.5 ± 103.8 μm) and bone (138.86 ± 105.67 μm) were larger than that in the cartilage tissue (87.5 ± 30.7 μm). The most frequently identified polymers were polypropylene (35 %), ethylene vinyl acetate copolymer (30 %), and polystyrene (20 %). The <em>in vivo</em> experiment suggested that microplastics invaded the bone, cartilage, and intervertebral discs through blood circulation after 4 weeks of exposure. Serum levels of tumor necrosis factor-α (TNF-α), Type Ⅰ procollagen amino-terminal peptide (PINP), and tartrate-resistant acid phosphatase-5b (TRACP-5b) were elevated compared with those in the control group (<em>p</em> &lt; 0.05). Our study suggests that microplastics invade the bone, cartilage, and intervertebral discs through the blood supply, causing distinct patterns of microplastic accumulation in these regions. Microplastic invasion can affect skeletal health by influencing the expression of inflammatory and bone morphogenetic cytokines. These findings provide insights into investigating the impact of microplastics on human skeletal health.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109316"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143083463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synchronous changes in mercury stable isotopes and compound-specific amino acid nitrogen isotopes in organisms through food chains","authors":"Dawei Wang ,&nbsp;Xiaoyuan Lin ,&nbsp;Gaoen Wu ,&nbsp;Zhidong Xu ,&nbsp;Jiemin Liu ,&nbsp;Xiaohang Xu ,&nbsp;Dongya Jia ,&nbsp;Longchao Liang ,&nbsp;Md. Habibullah-Al-Mamun ,&nbsp;Guangle Qiu","doi":"10.1016/j.envint.2025.109327","DOIUrl":"10.1016/j.envint.2025.109327","url":null,"abstract":"<div><div>The relationship between stable isotope of mercury (Hg, Δ¹⁹⁹Hg and δ²⁰²Hg) and compound-specific nitrogen isotope of amino acids (CSIA-AA, δ¹⁵N_Glu and δ¹⁵N_Phe) remains poorly understood. In this study, we investigated bird species and their prey in an abandoned Hg mining area, southern China to elucidate these correlations for a better understanding of Hg sources, biological transfer, accumulation and amplification through food chains. Our findings revealed distinct isotopic patterns: Δ¹⁹⁹Hg showed a positive correlation with δ¹⁵N_Glu, indicating trophic transfer processes, while a negative correlation with δ¹⁵N_Phe suggested differences in Hg sources among birds. The wide ranges of δ¹⁵N_Phe and Δ¹⁹⁹Hg observed in birds appear to reflect mixtures of multiple nitrogen and Hg sources, likely due to their diverse food sources and the large variation in the proportion of MeHg in total Hg (MeHg%). The consistent slope between Δ¹⁹⁹Hg/δ¹⁵N_phe and MeHg%/δ¹⁵N_phe, reflecting both energy and Hg sources, provides new insights into the biotransfer and accumulation of Hg in organisms. Notably, the trophic magnification factor (TMF) of MeHg observed in water birds, such as egrets, reached an exceptionally high value of 97.7 estimated from CSIA of multiple amino acids (i.e., TMF_M), underscoring the significance of investigating Hg sources in birds. Our results demonstrate that the synchronous changes between CSIA-AA and odd Hg isotopes effectively identify Hg sources and transfer across multiple ecological systems.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109327"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143393606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health and associated economic benefits of reduced air pollution and increased physical activity from climate change policies in the UK","authors":"Heather Walton ,&nbsp;David Dajnak ,&nbsp;Mike Holland ,&nbsp;Dimitris Evangelopoulos ,&nbsp;Dylan Wood ,&nbsp;Christian Brand ,&nbsp;Nosha Assareh ,&nbsp;Gregor Stewart ,&nbsp;Andrew Beddows ,&nbsp;Shawn YC Lee ,&nbsp;Daniela Fecht ,&nbsp;Yunzhe Liu ,&nbsp;Bethan Davies ,&nbsp;Anna Goodman ,&nbsp;Tuan Vu ,&nbsp;Sean Beevers","doi":"10.1016/j.envint.2025.109283","DOIUrl":"10.1016/j.envint.2025.109283","url":null,"abstract":"<div><div>Climate change policies do not always include analysis of air quality and physical activity co-benefits. We compared business as usual (BAU) UK policy with Net Zero scenarios from the UK Climate Change Committee for road transport and building sectors. We quantified and monetised the health benefits of the Balanced Net Zero (BNZP) and Widespread Innovation (WI) Pathways.</div><div>Air pollution concentrations were predicted using Chemical Transport Models and population-weighted. Shifts from car to walking and cycling for transport were converted to METhrs/week. Literature concentration–response functions were combined with baseline rates from routine statistics/other sources. Mortality and multi-morbidity impacts were calculated using lifetable analysis, and an incidence/prevalence model from 2019 to 2154 (a lifetime after 2050). Monetary values were applied to the results.</div><div>The BNZP policy compared with BAU gave 4.9 (95 % confidence interval 1.0–9.0) million life-years gained (LYG) (UK population, to 2154), including 1.1 (0.7–1.6) million LYG from active travel improvements. Avoided COPD and childhood asthma cases were 201,000 (150,000 – 250,000) and 192,000 (64,600–311,000). The monetised air quality morbidity benefits (£52.1 (36.4 – 67.8) billion) substantially added to the air quality mortality benefits (£77.9 (42.9 to 90.8) billion). Total yearly monetised benefits for BNZP vs BAU summed to 2154 (air pollution/active travel) were £153 (122 to 184) billion (core); 278 (228 to 334) billion (+outcomes with weaker evidence).</div><div>Adding the effects of air pollution reductions on disease incidence, with effects of air pollution and physical activity on mortality, increases the monetised benefits that may justify Net Zero policies in cost-benefit analysis.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109283"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142987928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors influencing the effectiveness of nature-based interventions (NBIs) aimed at improving mental health and wellbeing: An umbrella review","authors":"Topaz Shrestha ,&nbsp;Cheryl Voon Yi Chi ,&nbsp;Marica Cassarino ,&nbsp;Sarah Foley ,&nbsp;Zelda Di Blasi","doi":"10.1016/j.envint.2024.109217","DOIUrl":"10.1016/j.envint.2024.109217","url":null,"abstract":"<div><div>Several systematic reviews support nature–based interventions (NBIs) as a mechanism of enhancing mental health and wellbeing. However, the available evidence for the effectiveness of these interventions is fragmentary and mixed. The heterogeneity of existing evidence and significant fragmentation of knowledge within the field make it difficult to draw firm conclusions regarding the effectiveness of NBIs. This can only limit the development of interventions to support personal and planetary wellbeing, potentially resulting in ineffective and ill–targeted investment decisions. These concerns have hindered the translation of research evidence into practice and guidelines are urgently required to assist researchers, practitioners and policymakers in developing interventions to promote environmental stewardship and meet the health needs of diverse communities. A higher-order or <em>meta</em>-level synthesis is required to make sense of this evidence. This umbrella review synthesises evidence on the barriers and enablers to nature–based interventions through a summative review of existing published systematic reviews and <em>meta</em>-analyses. A systematic search in PsycINFO, PubMed, Greenfile, Web of Science, Embase, Scopus, Academic Search Complete (EBSCO), Environment Complete (EBSCO), Cochrane Library, CINAHL, Health Policy Reference Centre and Google Scholar was performed. This is a mixed method review, and systematic reviews with both quantitative and qualitative data synthesis were included. 64 systematic reviews were included in the synthesis. The descriptive data, extracted from each study, forms an overview of the characteristics of available evidence on nature-based interventions. A narrative synthesis is used to present the potential factors influencing the outcomes of NBIs. The risk of bias of the systematic reviews was assessed using a 16-item Assessment of Multiple Systematic Reviews 2 (AMSTAR2) checklist. Directions for future research, potential quality needs and recommendations for future research, policymaking, and practice are discusssed.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109217"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142917813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exposure to smoking and greenspace are associated with allergy medicine use – A study of wastewater in 28 cities of China","authors":"Lingrong Zhang ,&nbsp;Peng Du ,&nbsp;Qiuda Zheng ,&nbsp;Menglin Zhao ,&nbsp;Ruyue Zhang ,&nbsp;Zhenglu Wang ,&nbsp;Zeqiong Xu ,&nbsp;Xiqing Li ,&nbsp;Phong K. Thai","doi":"10.1016/j.envint.2025.109291","DOIUrl":"10.1016/j.envint.2025.109291","url":null,"abstract":"<div><div>Allergies have become an important public health issue as their occurrence is reportedly on the rise around the world. Exposure to environmental factors is considered as trigger for allergic diseases. However, there was limited data on the importance of each factor, particularly in China. In this study, we aimed to investigate the association between occurrence of allergic diseases with exposure to multiple environmental factors via wastewater surveillance across 28 cities in China. The surveillance was conducted by measuring biomarkers of proxies of allergic diseases, i.e. antihistamines, asthma drug, and of smoking, i.e. cotinine in wastewater. Data of green space and air quality were also collected. We observed the level of antihistamine use were significantly associated with smoking, green space and pollen but not significant with air pollution. People in Northern China used more antihistamines than their compatriots in Southern China, an observation aligning with previous reporting of more allergy prevalence in the North than the South of China. Our study affirmed that in China smoking is responsible for a rise in allergy and asthma in the population. Meanwhile, selected sensitizing pollens (occurring during summer) could have stronger impact to trigger allergies than other pollens (occurring in winter).</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109291"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142989166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Air pollution-related disease and economic burden in China, 1990–2050: A modelling study based on Global burden of disease","authors":"Dachuang Zhou ,&nbsp;Yang Yang ,&nbsp;Zhenping Zhao ,&nbsp;Kejia Zhou ,&nbsp;Di Zhang ,&nbsp;Wenxi Tang ,&nbsp;Maigeng Zhou","doi":"10.1016/j.envint.2025.109300","DOIUrl":"10.1016/j.envint.2025.109300","url":null,"abstract":"<div><div>The disease burden of air pollution (AP) has been well-documented, yet few studies have explored its economic burden. Retrieving disease burden data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021, this study constructed a cost-of-illness (COI) model to estimate China’s economic burden of AP in 1990 and 2021 and to identify national and provincial differences, then, an age-period-cohort (APC) model was adopted to estimate trends to 2050. Results demonstrated a serious load of AP, emphasizing the necessity for intervention. Nationwide, 2021 witnessed a decline in the disease burden compared to 1990, while economic burden increased during the same period. Evidence has shown that the significant reduction in the disease and economic burden of household air pollution from solid fuels (HAP) was attributed to the adoption of clean energy, offering insights into air pollution control for low- and middle-income countries (LMICs). While ambient particulate matter pollution (AMP) emerged as the leading cause of disease and economic burden in 2021, it is predicted to endure, particularly in provinces like Heilongjiang, Hebei, and Liaoning. Northern and inland regions bear a higher burden than southern and coastal do. Population aging exacerbates these challenges, urging stricter controls on AMP and protections for the elderly, thereby mitigating health and economic impacts caused by AP.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"196 ","pages":"Article 109300"},"PeriodicalIF":10.3,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}