Environment International最新文献

{"title":"Comparison of the rare earth element trophodynamics between freshwater and coastal species from the upper Yellow River to estuary: Insights into health risk","authors":"Xiang Gu ,&nbsp;Maoshan Lian ,&nbsp;Chunye Lin ,&nbsp;Zhongmin Lian ,&nbsp;Xiaoli Zhao ,&nbsp;Fengchang Wu","doi":"10.1016/j.envint.2025.109625","DOIUrl":"10.1016/j.envint.2025.109625","url":null,"abstract":"<div><div>Rare earth elements (REEs) are currently considered as contaminants of emerging concern, but their residual levels and trophic transfer in aquatic species and potential health risks are not fully characterized. This study compared the distribution patterns and trophodynamics of 15 REEs in the wild species of the Yellow River and adjacent Laizhou Bay of northern China. The daily intake of REEs through consuming aquatic products for Chinese residents was also estimated. The squids were characterized by the highest REE concentrations (5779–6102 μg/kg), followed by the sea snails, shrimps and crabs, and both the coastal and freshwater fish. Among different tissues of the <em>Silurus lanzhouensis</em>, gill played an important role in accumulating REEs and detoxication. The Eu and Ce anomalies of the aquatic organisms were consistent with those in sediments of their living habits, showing a common lithogenic origin. According to the bioaccumulation factor, no obvious bioaccumulation of REEs was observed for these aquatic species. Importantly, the relationships between the REEs and stable nitrogen isotopes (δ¹⁵N) suggested a significant trophic dilution of REEs in the coastal organisms. The estimated daily intake of REEs from consuming the aquatic organisms were relatively low, indicating the negligible health risk for Chinese adults. These results provide improved insights into the trophodynamics of REEs in the aquatic organisms and potential human health risks of REEs from consuming the aquatic products in China.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109625"},"PeriodicalIF":10.3,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Projected compound effects of population aging and climate warming on emergency ambulance demand in Japan","authors":"Lina Madaniyazi ,&nbsp;Kazutaka Oka ,&nbsp;Yasushi Honda ,&nbsp;Masahiro Hashizume","doi":"10.1016/j.envint.2025.109619","DOIUrl":"10.1016/j.envint.2025.109619","url":null,"abstract":"<div><h3>Background</h3><div>The emergency medical services system, including emergency ambulance dispatch (EAD), faces significant challenges due to a rapidly aging population and climate change. Notably, despite the warming climate, it remains unclear whether the high EAD incidence in winter will persist. This study projects the compound impact of these factors on future seasonal demands of EAD in Japan.</div></div><div><h3>Methods</h3><div>We analyzed 26,595,933 all-cause EAD cases among older adults in Japan in 2011–2019 and projected EAD incidence in 2011–99 under climate-population scenarios. We compared EAD incidence and its seasonality between 2011 and 2019 and future decades. Peak-to-trough ratio (PTR) and attributable fraction (AF) were used to measure the amplitude and burden of seasonality.</div></div><div><h3>Results</h3><div>Until mid-century, annual incidence cases are projected to rise by 15 %, followed by a decline afterwards. The annual incidence rate is expected to increase by 2.95 % to 4.25 % by the 2090s under various scenarios. Importantly, the high-incidence peak is projected to shift from cold to warm season, while high incidence in cold season persists. PTR and AF are projected to increase, with more profound changes under extreme climate scenario.</div></div><div><h3>Conclusion</h3><div>Demand for emergency medical services among older adults is expected to rise, especially until mid-century, with high demand in both summer and winter. Adaptive strategies are needed to manage increasing emergency service demands and shifts in seasonal patterns.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109619"},"PeriodicalIF":10.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of developmental and reproductive toxicity of biocides in consumer products using ToxCast bioassays data and machine learning models","authors":"Donghyeon Kim,&nbsp;Siyeol Ahn,&nbsp;Jinhee Choi","doi":"10.1016/j.envint.2025.109621","DOIUrl":"10.1016/j.envint.2025.109621","url":null,"abstract":"<div><div>Developmental and reproductive toxicity (DART) is a critical regulatory endpoint for protecting human health from chemical exposure. Biocides in consumer products are widely encountered in daily life, yet DART assessments often require substantial animal testing and are costly, leading to significant data gaps for these chemicals. This study aimed to identify ToxCast bioassays relevant to DART and develop machine learning models to screen biocides in consumer products for their DART potential. Initially, we compiled 201 bioassays linked to DART-related mechanisms using the Integrated Chemical Environment (ICE) database of the National Toxicology Program of (NTP). For these assays, we identified chemicals common to both ToxCast bioassays and in vivo ToxRefDB and conducted correlation analyses between bioactive concentrations (AC50) or hit-call data from in vitro assays and the lowest effect levels (LELs) from in vivo DART studies. This analysis revealed 25 bioassays with statistically significant correlations to in vivo DART data. Using the bioactivity data from these selected assays, we trained machine learning algorithms, including Random Forest, XGBoost, Gradient Boosting, Decision Tree, and Logistic Regression, on molecular fingerprints (MACCS, Morgan, Layered, RDKit). Based on the assumption that chemicals active in these ToxCast assays and their machine learning models may have DART potential, we prioritized active biocides in consumer products. For biocides with existing in vivo DART data, this approach achieved acceptable predictivity with F1 score of 76.2%. For biocides lacking in vivo DART data, we identified 100 active biocides as a high-priority group for further assessment. This study suggested the potential of ToxCast bioassays and machine learning models in predicting DART potential, offering a promising approach to address data-gap in consumer product safety.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109621"},"PeriodicalIF":10.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacts of port and locomotive-related air pollution on respiratory symptoms within vulnerable communities in Southern California","authors":"Jason G. Su ,&nbsp;Vy Vuong ,&nbsp;Eahsan Shahriary ,&nbsp;John Jacobsen ,&nbsp;John Balmes ,&nbsp;Meredith Barrett","doi":"10.1016/j.envint.2025.109618","DOIUrl":"10.1016/j.envint.2025.109618","url":null,"abstract":"<div><div>The increasing operations of port craft and railway locomotives pose significant environmental and health challenges to vulnerable communities in California, where disadvantaged populations often bear a disproportionate burden of pollution exposure. This study employs digital inhaler sensors to monitor individual respiratory health and quantify the impacts of air pollution from port craft and railway activities on rescue medication use. Combining spatially resolved emissions data with meteorological inputs, we utilized advanced dispersion modeling to estimate pollution levels, focusing on fine particulate matter with an aerodynamic diameter equal to or less than 2.5 µm (PM_2.5) and nitrogen dioxide (NO₂).</div><div>Our analysis revealed that a 10-µg m⁻³ increase in PM_2.5 concentrations is associated with a 3.42% rise in daily rescue medication use when accounting for NO₂ and PM_2.5 jointly. The impacts are particularly pronounced in deprivation-high communities, where the effect of PM_2.5 on rescue medication use is 3.8 times greater than in less disadvantaged areas. These findings highlight stark disparities in health outcomes, with marginalized populations facing heightened risks due to their proximity to emission sources and lack of adequate environmental safeguards.</div><div>While substantial research has addressed air pollution impacts from roadway traffic and industrial activities, studies focusing specifically on port craft and railway emissions remain limited. Our study demonstrates the unique health burdens associated with these underexplored sources of pollution. Furthermore, the use of digital health technologies allows for unprecedented spatiotemporal resolution in tracking exposure and respiratory outcomes, providing a more nuanced understanding of the complex interplay between environmental and health dynamics.</div><div>These results underscore the urgent need for targeted interventions, including cleaner technologies, stricter emission regulations, and policies aimed at mitigating exposure in vulnerable populations. Addressing these disparities is essential to advancing environmental justice and protecting public health.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109618"},"PeriodicalIF":10.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Movement ecology of a large ungulate following human abandonment of areas contaminated by the Fukushima Dai-ichi nuclear accident","authors":"Helen L. Bontrager ,&nbsp;Travis E. Stoakley ,&nbsp;Thomas G. Hinton ,&nbsp;Jeff Hepinstall-Cymerman ,&nbsp;Kei Okuda ,&nbsp;Takehuro Uno ,&nbsp;James C. Beasley","doi":"10.1016/j.envint.2025.109616","DOIUrl":"10.1016/j.envint.2025.109616","url":null,"abstract":"<div><div>The Fukushima Dai-ichi nuclear power plant disaster in the Tōhoku region of Japan resulted in the release of a large quantity of radionuclides into the environment; while humans were quickly evacuated from the contaminated area, wildlife remained. Changes in human activity and presence can impact habitat use and movement patterns of wild animals across demographic levels, including shifts in resource selection such as incursions into human-abandoned areas. Thus, understanding changes in spatiotemporal patterns of wildlife within human-abandoned landscapes can help mitigate human-wildlife conflict in preparation for anthropogenic resettlement. In this study, we investigated spatial utilization and temporal behaviors of Japanese wild boar (<em>Sus scrofa leucomystax</em>) in and around the Fukushima Exclusion Zone (FEZ). We used GPS data from 34 wild boar within the FEZ to conduct second- and third-order resource selection and movement path analyses. We also included GPS data from seven additional wild boar collared surrounding the FEZ to generate hidden Markov models to compare the temporal trends of wild boar inside the FEZ to wild boar outside the FEZ across three behavioral states (e.g., resting, foraging, traveling). We found that wild boar within the FEZ shifted their activity patterns to be more diurnal than those outside the zone where humans continue to reside. Additionally, while wild boar within the FEZ used natural spaces like forests, individuals also selected for human-abandoned areas such as rice paddy fields and urban areas. Our results provide insights into the adaptability of wildlife following human abandonment following large-scale human displacement events.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109616"},"PeriodicalIF":10.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel polyfurfuryl alcohol loose nanofiltration membrane for efficient dye/salt selective separation","authors":"Yalong Liu ,&nbsp;Fengni Luo ,&nbsp;Ke Zheng ,&nbsp;Shaoqi Zhou","doi":"10.1016/j.envint.2025.109622","DOIUrl":"10.1016/j.envint.2025.109622","url":null,"abstract":"<div><div>Loose nanofiltration (LNF) is a novel separation and purification technology to achieve organic wastewater treatment and sustainable recovery and recycling of available components in wastewater. However, it is still a formidable challenge to further improve the selectivity and permeability of LNF membranes in applications. In this study, Polyfurfuryl alcohol (PFA) LNF membranes with controllable pore structure were constructed from furfuryl alcohol (FA) on the surface of poly(ether sulfone) (PES) substrate by an acid-catalyzed in situ self-polymerization approach. By regulating the concentration of FA, the hydrophilicity, pore size distribution, and charge properties of the PES/PFA membranes were optimized to achieve the high flux and selective separation efficient. The results showed that the PES/PFA LNF membrane presented a uniform porous structure and exhibited considerable hydrophilicity and electronegativity. The optimized membrane (PES/PFA-2.0) exhibited excellent water flux (∼112.04 L m⁻² h⁻¹ bar⁻¹), high dye rejection (e.g. R_CR &gt; 98 %) and low rejection of salts (R_salts &lt; 15 %). The PES/PFA-2.0 membrane also exhibited a high dye/salt separation efficiency (e.g. CR/Na₂SO₄ selectivity ≈ 107.62). In addition, the PES/PFA-2.0 membrane demonstrated an excellent long-term stability and significant anti-contamination properties due to the rigid cross-linked network of PFA with hydrophilic and electronegativity surface modifications. The acid-catalyzed in situ self-polymerization of FA proposed in this study provides a feasible membrane separation solution for high-salt wastewater treatment and conforms to the demand of sustainable chemical development.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109622"},"PeriodicalIF":10.3,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of triclosan on cytokine production by human immune cells in vitro","authors":"Mai Homburg ,&nbsp;María Teresa Martín Monreal ,&nbsp;Åse Krogh Rasmussen ,&nbsp;Claus Henrik Nielsen ,&nbsp;Hanne Frederiksen ,&nbsp;Marya Morevati ,&nbsp;Ulla Feldt-Rasmussen","doi":"10.1016/j.envint.2025.109588","DOIUrl":"10.1016/j.envint.2025.109588","url":null,"abstract":"<div><h3>Background</h3><div>Triclosan, an antibacterial agent with structural similarity to thyroxine, is used in personal and industrial products. Increasing evidence demonstrates a negative influence of triclosan on both the endocrine and the immune system.</div></div><div><h3>Objectives</h3><div>The aim of this in vitro study was to characterize the effect of triclosan on cytokine responses of peripheral blood mononuclear cells (PBMCs).</div></div><div><h3>Methods</h3><div>Human PBMCs were exposed to triclosan and stimulated with lipopolysaccharide (LPS) or phytohemagglutinin-L (PHA-L) to stimulate primarily monocytes/macrophages of the innate immune system and T lymphocytes of the adaptive immune system, respectively, for 20–22 h. Cell viability was assessed. The cytokine response was quantified. Triclosan was measured in cell homogenate.</div></div><div><h3>Results</h3><div>The LPS-induced secretion of interleukin (IL)-1β and IL-10 by PBMCs was enhanced by co-incubation with 0.003, 0.3 and 3.0 µM triclosan, while the induced secretion of tumor necrosis factor (TNF)-α and IL-6 increased after co-incubation with 3.0 µM triclosan. The PHA-L-induced secretion of IL-2 was inhibited after co-exposure to 3.0 µM triclosan and of several further cytokines after co-exposure to 9.0 µM triclosan. The percentage of dead cells was increased in cultures incubated with 9 µM triclosan. After incubation of PBMCs with triclosan, triclosan was detected intracellularly.</div></div><div><h3>Discussion</h3><div>Our observations indicate a dose-dependent uptake of triclosan in PBMCs, and that triclosan enhances the cytokine secretion by LPS-stimulated PBMC, while inhibiting the pro-inflammatory response by PHA-stimulated PBMCs. Further investigations of the effect of triclosan are needed to uncover the potential risk of exposure to triclosan.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109588"},"PeriodicalIF":10.3,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in serum perfluorooctane sulfonic acid and perfluorohexane sulfonic acid concentrations in firefighters accessing a voluntary perfluoroalkyl and polyfluoroalkyl substances reduction treatment program","authors":"Ian Delaere ,&nbsp;Kerry Harris ,&nbsp;Sharyn Gaskin ,&nbsp;Yonatal Tefera ,&nbsp;Krystle Mitchell ,&nbsp;David Springer ,&nbsp;Simon Mills","doi":"10.1016/j.envint.2025.109609","DOIUrl":"10.1016/j.envint.2025.109609","url":null,"abstract":"<div><h3>Background</h3><div>In 2018/2019 a voluntary baseline biomonitoring survey (n = 916) identified firefighters at a fire station with substantially elevated serum perfluorooctane sulfonic acid (PFOS) and perfluorohexane sulfonic acid (PFHxS) concentrations. The South Australian Metropolitan Fire Service (SAMFS) initiated a voluntary treatment program (VTP) to address the impact of these exposures (participants n = 19). At the conclusion of the VTP, a retrospective analysis of a de-identified and coded serum PFOS and PFHxS concentration spreadsheet was conducted independently of the VTP.</div></div><div><h3>Objective</h3><div>This study reports longitudinal changes in serum PFOS and PFHxS concentrations and compares participants accessing the VTP with an observational group that did not seek treatment.</div></div><div><h3>Methods</h3><div>The dataset included a treatment group (n = 19) and an observation group (n = 9). The treatment group was further subdivided into three subgroups: (1) plasma donation (n = 2), (2) cholestyramine administration (n = 12), and (3) a combination of plasma donation and cholestyramine administration (n = 5). Repeat samples identified participants’ maximum and minimum serum PFOS and PFHxS concentrations. The calculations only included data from participants whose serum PFOS and PFHxS concentrations decreased. Apparent half-lives were estimated using one-compartment first-order elimination kinetics. The study did not conduct statistical comparisons; conclusions were drawn based on visual observations.</div></div><div><h3>Results</h3><div>The average change in serum concentration for the treatment group (PFOS: maximum decrease of 162 ng/mL, annual decrease of 41 %, with a half-life of 1.2 years; PFHxS: maximum decrease of 37 ng/mL, annual decrease of 32 %, with a half-life of 2.5 years) was compared with the observation group (PFOS: maximum decrease of 41 ng/mL, annual decrease of 12 %, with a half-life of 7.3 years; PFHxS: maximum decrease of 6 ng/mL, annual decrease of 10 %, with a half-life of 9.4 years).</div></div><div><h3>Conclusion</h3><div>This study shows that participants who received treatment eliminated PFOS and PFHxS from their serum at a greater rate than the observation group.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109609"},"PeriodicalIF":10.3,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144296364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dietary patterns and exposure to non-persistent endocrine-disrupting chemicals during pregnancy","authors":"Sarah Warkentin ,&nbsp;Sandra Márquez ,&nbsp;Hana Vespalcová ,&nbsp;Bethany Knox ,&nbsp;Mireia Gascon ,&nbsp;Nuria Güil-Oumrait ,&nbsp;Sandra González-Palacios ,&nbsp;Maria Dolores Gomez Roig ,&nbsp;Camille Lassale ,&nbsp;Elisa Llurba ,&nbsp;Matthieu Rolland ,&nbsp;Amrit K. Sakhi ,&nbsp;Cathrine Thomsen ,&nbsp;Jesús Vioque ,&nbsp;Mariona Bustamante ,&nbsp;Jordi Sunyer ,&nbsp;Martine Vrijheid","doi":"10.1016/j.envint.2025.109612","DOIUrl":"10.1016/j.envint.2025.109612","url":null,"abstract":"<div><h3>Background</h3><div>Exposure to non-persistent endocrine disrupting chemicals (EDCs) is widespread, causing various adverse health effects, especially during pregnancy. Diet is a major source of EDCs and the identification of dietary patterns that give rise to higher exposure levels is crucial. We aimed to explore the relationship between dietary patterns during pregnancy and exposure to non-persistent EDCs.</div></div><div><h3>Methods</h3><div>We included 640 pregnant women from the Barcelona Life Study Cohort (BiSC), Spain. Using food frequency questionnaires (2nd trimester), we estimated ultraprocessed food (UPF) consumption and Mediterranean diet adherence, and derived data-driven dietary patterns. Metabolites of phthalates, 1,2-cyclohexane dicarboxylic acid di(isononyl) ester (DINCH), chlorpyrifos and pyrethroid, polycyclic aromatic hydrocarbons (PAHs, including phenanthrenes), and organophosphates, and parent compounds of phenols and parabens were measured in weekly urine pools (3rd trimester). Associations between dietary patterns and EDCs were evaluated through multivariable linear regressions.</div></div><div><h3>Results</h3><div>Higher compliance with a “Vegetarian” pattern or the Mediterranean diet was associated with lower levels of some of the phthalate metabolites (e.g., di-<em>iso</em>-nonyl phthalates [Geometric mean ratio (GMR) per unit increases in the “Vegetarian” score = 0.97, 95 %CI 0.95, 1.00]). Conversely, “Western” and “Animal protein” patterns, and UPF intake were associated with higher PAHs (e.g., “Western” and 2-Hydroxynaphthalene [GMR(95 %CI) 1.07(1.01, 1.13)]), pesticides (e.g., “Animal protein” and 3-Phenoxybenzoic acid [1.15(1.01, 1.32]), and phthalates metabolites levels (e.g., UPF and Monoethyl phthalate [1.05(1.01, 1.09)]). No association remained significant after correcting for multiple testing.</div></div><div><h3>Conclusions</h3><div>Following a plant-based diet may help reduce the exposure to certain phthalate and organophosphate metabolites, whereas higher consumption of foods from animal origin and high in fat/sugar/salt may increase exposure to PAHs, pesticides, and phthalates metabolites in pregnancy.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109612"},"PeriodicalIF":10.3,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144305346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guidance on minimum information requirements (MIR) from designing to reporting human biomonitoring (HBM)","authors":"Maryam Zare Jeddi ,&nbsp;Karen S. Galea ,&nbsp;Jillian Ashley-Martin ,&nbsp;Julianne Nassif ,&nbsp;Tyler Pollock ,&nbsp;Devika Poddalgoda ,&nbsp;Konstantinos M. Kasiotis ,&nbsp;Kyriaki Machera ,&nbsp;Holger M. Koch ,&nbsp;Marta Esteban López ,&nbsp;Ming Kei Chung ,&nbsp;Jihyon Kil ,&nbsp;Kate Jones ,&nbsp;Adrian Covaci ,&nbsp;Yu Ait Bamai ,&nbsp;Mariana F. Fernandez ,&nbsp;Robert Pasanen Kase ,&nbsp;Henriqueta Louro ,&nbsp;Maria J. Silva ,&nbsp;Tiina Santonen ,&nbsp;Nancy B. Hopf","doi":"10.1016/j.envint.2025.109601","DOIUrl":"10.1016/j.envint.2025.109601","url":null,"abstract":"<div><div>Human biomonitoring (HBM) provides an integrated chemical exposures assessment considering all routes and sources of exposure. The accurate interpretation and comparability of biomarkers of exposure and effect depend on harmonized, quality-assured sampling, processing, and analysis. Currently, the lack of broadly accepted guidance on minimum information required for collecting and reporting HBM data, hinders comparability between studies. Furthermore, it prevents HBM from reaching its full potential as a reliable approach for assessing and managing the risks of human exposure to chemicals.</div><div>The European Chapter of the International Society of Exposure Science HBM Working Group (ISES Europe HBM working group) has established a global human biomonitoring community network (HBM Global Network) to develop a guidance to define the minimum information to be collected and reported in HBM, called the “Minimum Information Requirements for Human Biomonitoring (MIR-HBM)”. This work builds on previous efforts to harmonize HBM worldwide.</div><div>The MIR-HBM guidance covers all phases of HBM from the design phase to the effective communication of results. By carefully defining MIR for all phases, researchers and health professionals can make their HBM studies and programs are robust, reproducible, and meaningful. Acceptance and implementation of MIR-HBM Guidelines in both the general population and occupational fields would improve the interpretability and regulatory utility of HBM data. While implementation challenges remain—such as varying local capacities, and ethical and legal differences at the national levels, this initiative represents an important step toward harmonizing HBM practice and supports an ongoing dialogue among policymakers, legal experts, and scientists to effectively address these challenges. Leveraging the data and insights from HBM, policymakers can develop more effective strategies to protect public health and ensure safer working environments.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"202 ","pages":"Article 109601"},"PeriodicalIF":10.3,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144296365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}