Environment International最新文献

{"title":"A paradigm shift in environmental monitoring − The time for non-targeted analysis (NTA) is now","authors":"Mark J. Strynar","doi":"10.1016/j.envint.2025.109332","DOIUrl":"10.1016/j.envint.2025.109332","url":null,"abstract":"","PeriodicalId":308,"journal":{"name":"Environment International","volume":"197 ","pages":"Article 109332"},"PeriodicalIF":10.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic and geographic inequalities in exposure to projected hot and extreme summer days in England: A nationwide socio-spatial analysis","authors":"Jonathan R Olsen ,&nbsp;Claire Niedzwiedz ,&nbsp;Natalie Nicholls ,&nbsp;Benedict W Wheeler ,&nbsp;Frederick K Ho ,&nbsp;Jill P. Pell","doi":"10.1016/j.envint.2025.109351","DOIUrl":"10.1016/j.envint.2025.109351","url":null,"abstract":"<div><h3>Introduction</h3><div>Climate change is a global health emergency, with extreme heat events increasing morbidity, mortality, and hospitalisations, and exacerbating health and social inequalities. Global temperatures have risen by over 1.1 °C since pre-industrial times and could reach 2.5 °C or even 4.0 °C based on current policies.</div><div>This study examined how projected climate change will vary geographically and by population sub-group in England, to assess whether these changes will affect existing health inequalities.</div></div><div><h3>Methods</h3><div>We used small-area baseline (2001 to 2020) and climate projection data from the UK’s Met Office, linking it to area-level sociodemographic (2019) and health data (2016/17 to 2020/21), including age, socioeconomic status, ethnicity, hospital admissions, and mortality. Summated numbers of hot and extreme summer days were plotted by area-level health and sociodemographic quintiles. Models assessed the association between area-level quintiles and the projected number of hot (&gt;30 °C) and extreme (&gt;35 °C) summer days under 2.5 °C and 4.0 °C global heating scenarios.</div></div><div><h3>Results</h3><div>There were clear geographical variations in experiencing hot and extreme summer days, with the South of England seeing the highest increases. The pattern of projected temperature increases does not align with typical health inequalities, as less deprived areas will experience more hot and extreme summer days, while areas with larger ethnic minority populations will face a greater number.</div></div><div><h3>Conclusion</h3><div>Climate adaptation strategies are needed to two levels: (1) locally to support vulnerable population groups in coping with global heating; and (2) national and global strategies to prevent global temperatures from exceeding 2.5 °C or reaching 4.0 °C, given the severe population-level health risks such increases would entail.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"197 ","pages":"Article 109351"},"PeriodicalIF":10.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143496033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conducive circulation patterns and transport mechanisms for spring dust from Taklimakan Desert to the Tibetan Plateau","authors":"Xinyi Zhang, Tianhe Wang, Sichen Wang, Yingzi Jiao, Jingyi Tang, Jingtao Li, Fan Yang, Mansur O. Amonov, Sabur F. Abdullaev","doi":"10.1016/j.envint.2025.109356","DOIUrl":"https://doi.org/10.1016/j.envint.2025.109356","url":null,"abstract":"Dust aerosols have an impact on both public health and environmental health. The Taklimakan Desert (TD) serves as a significant source of high-altitude airborne dust over the Tibetan Plateau (TP). However, systematic understanding of its transport mechanism requires further exploration beyond isolated case studies. This study effectively identified the atmospheric circulation patterns and transport mechanisms that facilitate airborne dust movement from TD to TP in the spring, utilizing an obliquely rotated principal component analysis alongside various reanalysis and satellite datasets. The findings indicate that out of the five identified circulation patterns, three — specifically the northwest high-pressure (NWH), the northern high-pressure with warm anomaly (NH-W), and the northern high-pressure with cold anomaly (NH-C) — favor the occurrence of dust storms in the TD. In the NWH and NH-W patterns, dust is transported to the northeastern TP and the northwestern and central TP as a result of the interaction between dynamic, thermal, and terrain factors. This process features an elevated boundary layer, increased temperature, a steeper temperature lapse rate, and a more significant surface sensible heat flux in the TD. In contrast, the NH-C pattern restricts dust transport due to the presence of downdrafts along the north slope of the TP, and a reduced boundary layer and stable temperature stratification in the TD. This research provides valuable insights into the crucial function of atmospheric circulation in transporting dust from TD to TP, which is beneficial for assessing the condition of the cryosphere and developing environmental protection strategies.","PeriodicalId":308,"journal":{"name":"Environment International","volume":"16 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A decade of China’s air quality monitoring data suggests health impacts are no longer declining","authors":"Ben Silver,&nbsp;Carly L. Reddington,&nbsp;Yue Chen,&nbsp;Steve R. Arnold","doi":"10.1016/j.envint.2025.109318","DOIUrl":"10.1016/j.envint.2025.109318","url":null,"abstract":"<div><div>China’s national air quality monitoring network has revealed a rapid improvement in air quality during the 2010s, during which fine particulate matter (PM_2.5) and other priority pollutant levels fell, except for ozone, which concurrently increased. However, recent changes in China’s economic outlook mean that the future trajectory of China’s air quality is highly uncertain. Here we analyse the last 10 years of air quality monitoring data to assess whether China’s air quality has continued to improve in recent years. We find that the period of steep negative trends in PM_2.5 observed during 2014–2019 (−2.47 µg m⁻³ year⁻¹) has ended, slowing to −0.18 µg m⁻³ year⁻¹ during 2021–2024. Meanwhile, ozone levels continued to increase during 2021–2024, with a trend of 2.06 µg m⁻³ year⁻¹. We demonstrate that population PM_2.5 exposure in China can be accurately constrained using only surface monitoring station data, and we use this to estimate future health impacts under three observationally-based future PM_2.5 scenarios. We show that the current government PM_2.5 reduction target is insufficient to sustain the decrease in PM_2.5-attributed mortality that was achieved during 2014–2019, and a ∼2 times more ambitious target is needed to offset the effects of China’s ageing population.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"197 ","pages":"Article 109318"},"PeriodicalIF":10.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carbamazepine-exposed earthworms are characterized by tissue-specific accumulation patterns and transcriptional profiles","authors":"Chubin Zhang, Filipe Cabreiro, Leon P. Barron, Stephen R. Stürzenbaum","doi":"10.1016/j.envint.2025.109357","DOIUrl":"https://doi.org/10.1016/j.envint.2025.109357","url":null,"abstract":"Pharmaceutically active compounds enter soils via wastewater reuse and biosolid application. A ubiquitous drug present in wastewater is carbamazepine, a frequently prescribed anti-convulsant. Its mode of action is not species-specific and affects the nervous system of non-target organisms, including most likely the soil dwelling earthworms, which in turn has the potential to negatively impact soil quality. In this project, soils were amended with carbamazepine to explore uptake dynamics and resultant changes in molecular and life cycle endpoints of earthworms (<em>Dendrobaena veneta</em>). Earthworms were maintained, under laboratory conditions, for 28 days in soil spiked with either a solvent control, 0.6 mg/kg carbamazepine (encountered in the terrestrial system) or 10 mg/kg carbamazepine (significantly above an environmental hotspot). Carbamazepine concentrations were quantified in soils and worms by liquid chromatography tandem mass spectrometry (LC-MS/MS) which revealed tissue, dose and time-dependent differences in accumulation. Carbamazepine also modulated the make-up of the microbiome in the soil as well as the earthworm’s gut. <em>De novo</em> RNA sequencing identified novel transcripts and complex tissue-specific transcriptomic changes, where, for example, the expression of the <em>tubulin polymerisation promoting protein (tppp)</em> was inhibited (9-fold) in the gut but induced (11-fold) in the cerebral ganglion of exposed earthworms. However, the notable absence of a strong cytochrome P450 response across all conditions suggests that the terrestrial earthworm also relies on detoxification pathways that differ to those observed in well-studied aquatic models. The novel finding that carbamazepine exposure triggers tissue-specific impacts in non-target soil organisms highlights the value and need for a more comprehensive understanding of how contaminants of emerging concern behave within an ecotoxicological context. This, in turn, will lead to informed and reliable risk assessments defining the consequences of wastewater and biosolid amendment practices on soil ecology and ecosystem function.","PeriodicalId":308,"journal":{"name":"Environment International","volume":"5 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular mechanistic insights towards aggregation of nano-biochar moderated by aromatic components in dissolved organic matter","authors":"Zheng Zhou ,&nbsp;Meng Lu ,&nbsp;Yu Huang ,&nbsp;Changping Zhao ,&nbsp;Yafeng Wang ,&nbsp;Marc Pidou ,&nbsp;Min Wu ,&nbsp;Quan Chen ,&nbsp;Paul Jeffrey ,&nbsp;Bo Pan","doi":"10.1016/j.envint.2025.109350","DOIUrl":"10.1016/j.envint.2025.109350","url":null,"abstract":"<div><div>Nano-biochar (NBC) is a promising tool for sustainable remediation of contaminants in aquatic environments. However, the presence of ubiquitous ions and dissolved organic matter (DOM) can impact NBC aggregation, resulting in reduced application efficacy and potential ecological risks. Understanding and regulating NBC aggregation offers valuable insights for its deployment. This study integrated batch aggregation experiments, theoretical models, Fourier transform ion cyclotron resonance-mass spectrometry (FTICR-MS), and density functional theory (DFT) calculations to explore the behaviors and mechanisms of NBC aggregation with coexisting ions and model DOM. NBC aggregation kinetics followed the classical Derjaguin-Landau-Verwey-Overbeek (DLVO) theory in both NBC-ions and NBC-ions-fulvic acid (FA) solutions, indicating that the aggregation process is controlled by Van der Waals forces and electrostatic repulsion. Mono/di-valent electrolytes promoted NBC aggregation, whereas FA moderated it, with higher molecular weight FA fractions exhibiting superior performance. Three-dimensional excitation-emission (3D-EEM) fluorescence spectra and Parallel factor analysis (PARAFAC) analyses revealed that HA-like substances, followed by FA-like substances, can form a complex with ions, thereby moderating NBC aggregation. FTICR-MS scans identified lignin substances with aromatic structures as key components that effectively reduce the promoted NBC aggregation with coexisting mono/di-valent electrolytes. DFT calculations confirmed that the aromatic structures in FA spontaneously form complexes with electrolytes, thereby potentially regulating NBC aggregation. This research highlights potential strategies for regulating NBC applications and offers insights into the behavior of nanoparticles in aquatic environments.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"197 ","pages":"Article 109350"},"PeriodicalIF":10.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nationwide prediction of pesticide residual levels in soil: Implications on the resulting risk and prioritization framework","authors":"Bin Zhang, Hongyu Mu, Hua Li, Xianghua Zhang, Guang Yang, Wenxiu Chen, Yan Yan, Wei An, Min Yang","doi":"10.1016/j.envint.2025.109355","DOIUrl":"https://doi.org/10.1016/j.envint.2025.109355","url":null,"abstract":"Pesticides are widely accumulated in agricultural soils in China under successive applications, causing negative impacts on non-target species and environmental qualities. However, a nationwide overview of the residual levels of pesticides in soil, and the ecological risks to non-target soil species are lacking. In this study, we calculated geographically gridded concentrations of 107 pesticide active ingredients (AIs) in soils in China based on the Computational Pesticide Input (CPI) model and further assessed the ecological risks to soil biota. In the end, we proposed an integrated usage-impact model to identify prioritize control pesticides based on the usage, risk and persistence of pesticides. Pesticide concentrations were calculated in a range from 0.01 mg kg⁻¹ to over 185 mg kg⁻¹. Glyphosate is the most prevalent pesticide that exists in most locations. The ecological risks were mostly assessed as medium risk, with extreme high- and high risk found in 1 % and 21 % of soils. Supervision and management of azoxystrbin, boscalid, butachlor and chlorpyrifos need to be prioritized. The results of this study provide guidance to local governments for the designation more accurate risk mitigation strategies across regions.","PeriodicalId":308,"journal":{"name":"Environment International","volume":"15 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143526063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcriptome alterations in long-term mining region residents: Insights into immune response and molecular pathways","authors":"Ani Stepanyan ,&nbsp;Arsen Arakelyan ,&nbsp;Jonathan Schug","doi":"10.1016/j.envint.2025.109344","DOIUrl":"10.1016/j.envint.2025.109344","url":null,"abstract":"<div><div>Pollution with metals and metalloids is a global problem that adversely affects human health and environment. Although several studies have reported gene expression changes in response to human exposures to metals, there are a limited number of studies exploring the effect of long-term residence in mining areas. The evidence of increased levels of several essential and non-essential metals in soil, water, and plants in Kapan mining area (Armenia) has been previously demonstrated in several environmental studies. Our study investigated the impact of long-term residence in this mining area on the transcriptome state of human peripheral blood mononuclear cells and the possible association of transcriptome changes with the blood metallome.</div><div>In total, 58 participants including 27 mining region residents (MRR) and 31 non-mining region residents (NMR) were selected for our study. Transcriptomic analysis of peripheral blood mononuclear cells was performed by mRNA sequencing. Differential expression analyses were conducted using generalized linear modeling, optimized for participant demographics, cell types, and sequencing technical factors, followed by pathway analysis.</div><div>The study revealed that long-term residence in a mining area is correlated with alterations in the blood transcriptome, with responses varying by sex. The identified transcriptome changes were enriched for pathways related to immune response and RNA translation. These changes correlated with higher blood levels of a mixture of non-essential metals, including arsenic, antimony, nickel, thallium, and beryllium. Additionally, the study identified differences in the transcriptome response between male and female MRR. While females exhibited a stronger immune response, males show dysregulation in ion transport and epigenetic modifications. Our findings contribute to understanding the effects of long-term residence in mining regions and can aid in developing more effective risk assessment and mitigation approaches in target populations.</div></div>","PeriodicalId":308,"journal":{"name":"Environment International","volume":"197 ","pages":"Article 109344"},"PeriodicalIF":10.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxicity enhancement of microplastics released from food containers through thermal aging: Absorbing more serum proteins thus activating the innate immune response via actin polymerization","authors":"Fang Du, Meiqian Hou, Song Lu, Xiaotian Ding, Ling Zhang, Yajie Du, Zhen An, Wenwen Cai, Leicheng Zhao, Weidong Wu, Zhiguo Cao","doi":"10.1016/j.envint.2025.109358","DOIUrl":"https://doi.org/10.1016/j.envint.2025.109358","url":null,"abstract":"This study examined the effects of hot high-fat simulants on the physicochemical properties of microplastics (MPs) from polypropylene (PP)-, low-density polyethylene (LDPE)-, and polylactic acid (PLA)-based single-use food container (SUFC) leachates and those of aging on their immunomodulatory effectors. Scenario studies have demonstrated that MPs were released from these three types of SUFCs. LDPE- and PLA-based SUFCs also released cellulose. Among the SUFCs, only the PP leachates particles exhibited a new absorption peak at 1725 cm⁻¹, which aging phenomenon may be attributed to the presence of unstable tertiary carbon atoms. Subsequently, we investigated the immunomodulatory effects of removing additive both PP and thermal-aged PP with polystyrene (PS) and carboxyl-modified PS (PS-COOH) polymer backbones as reference materials. The findings indicated that thermal-aged PP and PS-COOH induced comparable innate immune responses, with PS-COOH particles exhibiting a similar size to SUFC percolates. Consequently, PS and PS-COOH were selected as original and thermal-aged MPs, respectively, to evaluate the effects of aging on innate immunity. The results revealed that<!-- --> <!-- -->a protein corona formed on both particle types, with more protein adsorption observed on PS-COOH particles. The complex enhanced the phagocytosis of RAW264.7 macrophages and increased the expression of pro-inflammatory genes <em>NOS2</em> and <em>TNF-α</em> through an actin polymerization cross-linking mechanism. In this study, we investigated how thermal-aged MPs affect innate immune responses using PS-COOH as a model system, emphasizing the importance of a comprehensive safety evaluations of MPs.","PeriodicalId":308,"journal":{"name":"Environment International","volume":"130 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-omics association pattern between gut microbiota and host metabolism of a filter-feeding fish in situ exposed to microplastics","authors":"Jun-Nan Huang, Cong-Cong Gao, Hong-Yu Ren, Bin Wen, Zhuo-Nan Wang, Jian-Zhong Gao, Zai-Zhong Chen","doi":"10.1016/j.envint.2025.109360","DOIUrl":"https://doi.org/10.1016/j.envint.2025.109360","url":null,"abstract":"Microplastics (MPs) are widespread in water environments and can affect gut microbiota and host metabolism of fish, but whether changes in host metabolism under MPs are mediated by gut microbiota remains unclear. Here, silver carp, a filter-feeding fish with important ecological functions, was <em>in-situ</em> exposure to environmentally relevant MPs. Multi-omics analysis and fecal microbiota transplantation were used to reveal the metabolic responses of carp along gut-liver-muscle axis. After three months of <em>in situ</em> exposure to MPs, community structure of gut microbiota of carp was reshaped, and five dominate phyla were significantly changed, including increased Cyanobacteria, Chloroflexi and Planctomycetota but decreased Firmicutes and Fusobacteriota. Weighted gene co-expression network analysis was further performed between these phyla and liver transcription spectrum, showing that the hub gene module contained up-regulated <em>hppD</em>, <em>maiA and plg</em> and activated ubiquinone and other terpenoid-quinone biosynthesis and phenylalanine metabolism. By fecal microbiota transplantation, the key gene module associated with core microbiota phyla of carp was verified in germ-free zebrafish. Interestingly, up-regulated <em>hppD</em>, <em>maiA and plg</em> and enriched phenylalanine metabolism were also observed in this module. Subsequently, metabolome performed in carp liver also shared activated phenylalanine metabolism, including increased <em>trans</em>-cinnamic acid and L-tyrosine. Furthermore, high-associated mapping showed that the differentially expressed metabolites (gamma-aminobutyric acid, ornithine and L-serine) related to amino acid metabolism in carp muscle were significantly accompanied with increased L-tyrosine in its liver. Overall, MPs exposure could change gut microbiome of silver carp and alter host metabolism especially amino acid metabolism along the gut-liver-muscle axis.","PeriodicalId":308,"journal":{"name":"Environment International","volume":"52 1","pages":""},"PeriodicalIF":11.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}