ScienceRisePub Date : 2021-08-31DOI: 10.21303/2313-8416.2021.002036
Shaka Yesufu
{"title":"The socio-economic impact of the Covid-19: a South African perspective on its impact on the socio-economic, inequality, security, and food systems","authors":"Shaka Yesufu","doi":"10.21303/2313-8416.2021.002036","DOIUrl":"https://doi.org/10.21303/2313-8416.2021.002036","url":null,"abstract":"The objects of this research are: first, to highlight some of the socio-economic impact, arising out of the government's strict lockdown rules due to the Covid-19 pandemic. Second, to explore the psychological effects of the new normal on citizens, arising out of the lockdown. \u0000The author investigated the following problems: social problems, caused by restricted movements, increase interpersonal violence crimes, and economic problems due to job losses, emanating from several businesses closures. \u0000The main results of the research are: very high number of death rates with over (78 000), succumbing to coronavirus in South Africa, high unemployment, threats of food scarcity, educational setbacks due to schools closure, economic inequality gap, more widely pronounced, and hospitals, put under severe pressure due high patients needs. \u0000The area of practical use of the research is for all citizens, directly affected by the global pandemic. The research highlights the significance of the use of technology to inform and support lifelong learning using more e-learning platforms as an alternative for the old pedagogic delivery of lectures. \u0000The innovative technological products, arising out of the lockdown, were several e-learning softwares introduced. Apps like ‘uber eats; Vromo; Open Table; and ChatFood were all introduced and made delivery of fast food to our homes relatively easy. Several e-learning products were made popular: Microsoft teams; Zoom; Skype; Canvas; Ariculate 360; 7 taps; Spayee and teachable. \u0000The Scope of the innovative technology products were more pronounced in both the hospitality, catering industries, and educational institutions.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48274708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2021-06-30DOI: 10.21303/2313-8416.2021.001917
M. Porokhnia, O. Shestopalov, S. Bukhkalo, T. Novozhylova
{"title":"Influence of structural descriptions of underbody of bicarbonate columns on duration of period of their operation and ecologization of process","authors":"M. Porokhnia, O. Shestopalov, S. Bukhkalo, T. Novozhylova","doi":"10.21303/2313-8416.2021.001917","DOIUrl":"https://doi.org/10.21303/2313-8416.2021.001917","url":null,"abstract":"Object of research: optimization of the operation period of bicarbonate columns by optimizing their design features. \u0000Investigated problem: increasing the efficiency, environmental friendliness and duration of the bicarbonate columns by optimizing the design of the sludge discharge unit. \u0000Main scientific results: the article analyzes the main design features of bicarbonate columns for the production of purified sodium bicarbonate. A relationship has been established between the design of the apparatus, the intensity of mixing and the duration of the apparatus operation without stopping for washing. On the basis of the existing problems, laboratory and industrial experiments were carried out at one of the soda plants, aimed at increasing the efficiency of operation of the bicarbonate columns of the purified sodium bicarbonate shop. So, due to the modernization of the design of the sludge unloading unit and the identification of the optimal amount and month of the location of the mesh trays, an increase of 1.5-2 times in the duration of operation of the columns without stopping for washing was achieved. This contributed to an increase in plant productivity and environmental friendliness of the process due to a decrease in the amount of liquid waste generated during the washing of the column equipment. \u0000Area of practical use of the research results: enterprises for the production of purified sodium bicarbonate of food and pharmaceutical quality. \u0000Innovative technological product: design solutions for bicarbonate columns and the technology of carbonization of soda-bicarbonate solution for the production of purified sodium bicarbonate. \u0000Scope of application of the innovative technological product: soda production, food and pharmaceutical industries.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41475004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2021-06-30DOI: 10.21303/2313-8416.2021.001920
K. Mammadov, H. Shiraliyeva, Elnur Ismikhan Mehtiyev, U. Aliyeva-Jabbarly, Elchin Ilham Guliyev, N. Mirzayev, A. Huseynova
{"title":"Studying the treatment processes of soil samples from radionuclides","authors":"K. Mammadov, H. Shiraliyeva, Elnur Ismikhan Mehtiyev, U. Aliyeva-Jabbarly, Elchin Ilham Guliyev, N. Mirzayev, A. Huseynova","doi":"10.21303/2313-8416.2021.001920","DOIUrl":"https://doi.org/10.21303/2313-8416.2021.001920","url":null,"abstract":"Object of research: Soil samples contaminated with radionuclides and processes for treatment of contaminated soil. \u0000The problem to be solved: Isolation of radionuclides from contaminated soil samples by extraction with weak solutions of acids and alkalis. \u0000Main scientific results: Treatment of soil samples contaminated with uranyl nitrate using extraction with weak solutions of nitric and hydrochloric acid, caustic sodium and subsequent washing of soil residues with distilled water is effective process and leads to a more than tenfold decrease in the content of uranium isotopes (U238, U235, U234 and U236) in the soil samples. At the same time, there is a decrease in the content of natural radionuclides (Na22, K40, Zn65, Sn113, Sn126) in the extracted soil samples. An increase in their content in the extract of the analyzed soil samples corresponds to a decrease in their content in the residue of the extracted soil samples. The analysis of the values of the decrease in the content of natural radionuclides in the soil contaminated with uranyl nitrate corresponds to the values of the decrease in their content in the identical soil, but not contaminated with uranium isotopes. The combined extraction with weak solutions of acids and alkalis leads to the enrichment of the soil with nitrates and chlorine-containing compounds. \u0000The area of practical use of the research results: Subdivisions of the Ministry of Emergency Situations and Chemical Troops specializing in the study of emergencies and natural disasters can use the results of these studies in the elimination of the consequences of global environmental disasters and incidents that pose a threat to the life of the civilian population and the personnel of paramilitary units. \u0000Innovative technological product: The proposed method for treatment of soil contaminated with radionuclides makes it possible to more than tenfold reduce their concentration in the soil. \u0000Scope of application of an innovative technological product: treatment of contaminated soil in areas affected by nuclear tests or accidents at nuclear power plants.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44705571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2021-06-30DOI: 10.21303/2313-8416.2021.001904
D. Fedorova
{"title":"Formal differentiated approach to managing women with stress urinary incontinence","authors":"D. Fedorova","doi":"10.21303/2313-8416.2021.001904","DOIUrl":"https://doi.org/10.21303/2313-8416.2021.001904","url":null,"abstract":"ABSTRACT \u0000The object of research: treatment of women with stress urinary incontinence (SUI). \u0000Investigated problem: substantiation of the choice of treatment methods in the management of women of different ages with SUI depending on the urogynecological status, age, financial capabilities, risk of complications and speed of achieving the desired result. \u0000The main scientific results: An approach has been developed to substantiate the most rational method of treatment of women of different ages with SUI, taking into account the provision of an adequate standard of living. It is based on the use of hierarchy analysis, which allows to determine the priorities between competing treatments - mid-urethral sling (MUS), pelvic floor muscle training (PFMT) and containment (absorbent pads). The expediency of applying a formal differentiated approach is confirmed by the results of questionnaires of representative groups of women on the technology of UDI-6 and IIQ-7 questionnaires before and after treatment. It is recommended to choose a rational method of treatment or a set of treatment methods personally depending on the urogynecological status, age, financial capabilities, risk of complications and speed of achieving the desired result. MUS has gained the highest number of points due to the short time of treatment and rehabilitation, long-term postoperative effect, accessibility, low level of complications and significant improvement of life quality in young and elderly women. The most rational method of treatment of middle-aged patients with SUI is the method of PFMT as one that has a positive impact on the life quality of women and does not require financial costs. \u0000The area of practical use of the research results: medical institutions providing urogynecological care to women. \u0000Innovative technological product: development of a formal differentiated approach to the management of women with SUI, which allows to choose the most rational method of treatment taking into account the life quality. \u0000Scope of the innovative technological product: clinical practice of treatment of women with SUI.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47533163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2021-06-30DOI: 10.21303/2313-8416.2021.001919
N. Blazhennyi, O. Turovsky, L. Kyrpach, Y. Kremenetskaya, O. Zhukova
{"title":"Development of methods for the assessment of vulnerability of the receiver input of free-space optical communication from the effects of radiation, as the effects of the destruction of radiation hazardous objects","authors":"N. Blazhennyi, O. Turovsky, L. Kyrpach, Y. Kremenetskaya, O. Zhukova","doi":"10.21303/2313-8416.2021.001919","DOIUrl":"https://doi.org/10.21303/2313-8416.2021.001919","url":null,"abstract":"Object of research: Free-space optical communication (FSO). \u0000Investigated problem: Significant advantages of free-space optical communication in comparison with the existing networks of useful data transmission justify their use in various complex environmental conditions, which require the organization of fast and reliable digital communication when it is impossible or limitation to use wired or radio lines. \u0000Main scientific results: One of the factors that can considerably affect the FSO efficiency is radioactive radiation produced by various sources and phenomena of ionizing effects. In the research the issues of the assessment of the vulnerability of the FSO receivers of input signal from the effects of gamma radiation are directly considered. The analysis of the design of the receiving path of the input signal of FSO is conducted and the list and the partial attenuation coefficients of radioactive radiation by the FSO components that separate the receiver of input signal from the external environment are determined. \u0000The area of practical use of research results: The methods has been developed and with its help the assessment of the vulnerability of the FSO receivers of input signal from the effects of gamma radiation, as the effects of the destruction of the radiation-hazardous object has been conducted. \u0000Innovative technological product: The nature of the influence of gamma radiation as the effects of the destruction of the radiation-hazardous object on the FSO receiver of input signal is determined. \u0000Scope of application of an innovative technological product: The results allow to develop a set of measures aimed at reducing the effects of gamma radiation, as the effects of the destruction of the radiation-hazardous object, on the FSO efficiency.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42943055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2021-06-30DOI: 10.21303/2313-8416.2021.001927
S. Pylypenko
{"title":"Technologization of human of the postmodern age as a challenge to the natural reality of the earth","authors":"S. Pylypenko","doi":"10.21303/2313-8416.2021.001927","DOIUrl":"https://doi.org/10.21303/2313-8416.2021.001927","url":null,"abstract":"Object of research: technology as a component of human social life in the context of the postmodern era. \u0000Investigated problem: determination of the features of the influence of technological processes on a person of the postmodern era, as a result of which the natural is replaced by an artificial one and the images of both man and the Earth change. \u0000Main scientific results: the study of the contradictions of the process of technologization in the postmodern era made it possible to determine the transformation processes taking place in the life of a person and society. This defines social reality, represented by various markers, among which technology is gaining in importance. The latter act as a composite, which provides new opportunities for determining the relationship between the elements of the \"world - man - culture\" system. It is not only about the emergence of new human figures, among which the technological man (Homo Technologicus) occupies a prominent place, but also the emergence of a new image of the Earth, where the natural is replaced by the technological. \u0000The scope of practical use of the research results: the research results can be used in teaching normative courses \"Philosophical Anthropology\", \"Ethics\", \"Sociology\" for students and undergraduates, graduate students of humanitarian and natural faculties. \u0000Innovative technological product: the plurality of existing technologies (economic, medical, educational, humanitarian, etc.) destroys the new European concept of culture and man, which were provided within the framework of the monoparadigm. The anthropological dimension of technology testifies that the latter are beginning to act as a condition for human expansion. This situation has a significant impact on the existentials of human existence. \u0000The scope of using the innovative technological product: the intensive technologization of the last decades not only provokes environmental risks and changes the state of the Earth, the natural reality of the Earth is replaced by an artificial one, which allows to conclude that the Earth is formed by a technological one.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45571524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2021-04-30DOI: 10.21303/2313-8416.2021.001816
O. Patlasov, Y. Fedorenko, D. Shulha
{"title":"Development of methods to increase the efficiency of railway maintenance","authors":"O. Patlasov, Y. Fedorenko, D. Shulha","doi":"10.21303/2313-8416.2021.001816","DOIUrl":"https://doi.org/10.21303/2313-8416.2021.001816","url":null,"abstract":"Object of research: technology of track maintenance optimization \u0000Solved problem: In the development of decisions to optimize the decision-making system in the content of the upper structure of the track used methods of control theory, systems analysis, methodology of optimal control. \u0000Main scientific results: An analysis of the degrees of research on improving the efficiency of the technical management of railways showed that there was no systematic approach and that existing developments in the organization, in particular the relative optimization, Separate track repair standards or take into account parameter models, process requirements and conditions. \u0000Area of practical use of research results: industrial enterprises, railway stations. \u0000Providing the stable support of the railway, sustainable and rhythmic operation of railway traffic is ensured. About 7.3 thousand km are exploited in the ferrous metallurgy of Ukraine. More than 70 % of routes are up to 500 km long and belong to a large company. Consequently, an important task is to maintain the technical state of railways at the production demands level. \u0000Innovative technological product: combined transportations that can interact with similar networks of foreign countries. \u0000Scope of application of innovative technological product: formation and effective functioning of railway-transport complex, improvement of tariff policy, substantiation of perspective parameters of transportation process and its technical means, creation of advanced technologies, choice of rational structure of transport network, formation of transport corridors, development of fundamentally new management systems.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":"1 1","pages":"11-22"},"PeriodicalIF":0.0,"publicationDate":"2021-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44495249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2020-12-30DOI: 10.21303/2313-8416.2020.001497
L. Bogush
{"title":"FEATURES AND PROSPECTS OF THE ECONOMIC RENT FROM WORKFORCE AND SOCIAL CONDITIONS IN UKRAINE","authors":"L. Bogush","doi":"10.21303/2313-8416.2020.001497","DOIUrl":"https://doi.org/10.21303/2313-8416.2020.001497","url":null,"abstract":"Object of research: the article presents the results of studying the economic rent from workforce and social conditions (significant components of the important rent-forming resource of nowadays global economy – social capital) in Ukraine. Solved problem: determining the features of economic rent, outlining the conditions and prospects for increasing the rental income of the Ukrainian economy from the capitalization of workforce’ intellectual and creative qualities, as well as socium rent-generating conjunctures. Main scientific results: the role of the economic rent in the system of rental relations of the modern global economy and its national components is examined; the features of the formation and distribution of economic rent’ various types in the process of using the workforce’ intellectual and creative potential, as well as other components of the nowadays most significant type of rent-forming resources – social capital – are studied. The specificity of human component and social capital in general as a rent-generating resource is manifested in the generation of additional prerequisites (resource, organizational and economic) and incentives to increase volumes and expand potential areas for extracting rent income in the process of its use, since the using of the employee’ knowledge and abilities leads to a consistent accumulation of professional experience, and consequently – to a permanent increase in the aggregate of these rent-generating properties and in activities for improving the environment of their implementation in Ukraine. Scope of practical use of research results: the research results can be used in developing strategies and programs of Ukrainian economy’ innovative diversification in the process of its further competitive integration into the global economic space, that, among other things, requires the creation of conditions for improving the rent-generating properties of workforce and social environment, as well as increasing the level of its capitalization.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46326100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2020-12-30DOI: 10.21303/2313-8416.2020.001558
D. Korol, A. Yefimenko, M. Korol
{"title":"COMPARISON OF THE CONDITION OF THE PERI-IMPLANT ORAL MUCOUS ACCORDING TO THE RESULTS OF DIGITAL MICROSCOPY","authors":"D. Korol, A. Yefimenko, M. Korol","doi":"10.21303/2313-8416.2020.001558","DOIUrl":"https://doi.org/10.21303/2313-8416.2020.001558","url":null,"abstract":"The object of the study there is a level of hyperemia of the mucous membrane around the installed intraosseous dental implants with different coating material according to the results of histogram analysis of digital microscopy. The problem to be solved – evaluation of the degree of hyperemia of the periimplant mucosa around intraosseous dental implants coated with rutile, in comparison with titanium implants of VT-6 alloy after prosthetics. Main scientific results: Analysis of digital images using histogram evaluation of the red component of the spectrum showed that 1 month after prosthetics in group 1, which included 20 patients who had intraosseous implants made of titanium alloy TiV6Al (VT-6), the above indicator increased to 191 (St.Err. 4.45). The difference was 4 conventional units. Similarly, in group 2 (16 people) who had intraosseous zirconium implants, there was an increase in the quantitative rate after prosthetics by 9 conventional units, and its value was 194 conventional units (St.Err. 3.64). Since increasing numerical values and shifting the digital histogram to the right is an objective criterion for reducing the intensity of redness, it can be concluded that there is a reduction of mucosal irritation after orthopedic treatment with a predominance of this process in the group of patients who received intraosseous dental implants coated with rutile. The area of practical use of research results: Since the authors first studied the reaction of the peri-implant mucosa in contact with various implant materials at the stages of orthopedic treatment, this is the basis for the introduction into general medical practice of intraosseous dental implants made in Ukraine using rutile application technology. The area of application of an innovative technological product - it is a dental implant practice. The obtained results will allow to use more widely Ukrainian implants of non-demountable construction with a high level of surface preparation, for the purpose of further orthopedic treatment with the use of non-removable metal-ceramic dentures.","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42394705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ScienceRisePub Date : 2020-12-30DOI: 10.21303/2313-8416.2020.001549
O. Kuzenko, Y. Demin, Y. Kuzenko
{"title":"RESEARCH OF REPARATIVE MECHANISMS IN THE OPTIC NERVE IN TOXIC NEUROPATHY CAUSED BY Cr (VI)","authors":"O. Kuzenko, Y. Demin, Y. Kuzenko","doi":"10.21303/2313-8416.2020.001549","DOIUrl":"https://doi.org/10.21303/2313-8416.2020.001549","url":null,"abstract":"Intoxication lesions of the optic nerve (toxic optic neuropathy, TON) most often occur under the influence of exogenous factors, including heavy metals. Сell survival under stress have involves heat shock proteins (HSPs). The aim of the research. To assess the optic nerve’s immunoreactivity to heat shock proteins of the HSP70 and HSP90α families and reveal its relationship with the severity of morphological changes in toxic optic neuropathy caused by Cr (VI). Materials and methods. The study was conducted on 48 mature male rats. The experimental groups were given to drink water with Cr(VI) for 20, 40 and 60 days. This type of water is typical for the water basins in the northern districts of the Sumy region. Optic nerves сhanges under the influence of Cr(VI) have investigated by the morphometric method. Neuroglial cells and capillary endothelial cells were assessed by immunohistochemistry by HSP70α and HSP90 expression for intensity and spatial distribution. Results. The data analysis revealed that Cr (VI) has a neurotoxic effect on the optic nerve with the development of edema, which is manifested by the thickening of nerve fibers. The dynamics of HSP70 immunoexpression in the endothelium of the optic nerve capillaries of rats on 20 and 40 experimental days was characterized by stable values and was 1.5 times higher than the control. The maximum number of positively stained cells for the HSP70 marker was detected in endothelial cells of the microvasculature for 60 days – 82.44±12.42 %. HSP70 levels in neuroglia cells of optic nerve have decreased on day 40 (55.66±11.56% p=0.05) and lower than the control (70.44±4.81 %.) group. Optic nerve capillaries was highest immunoactivity on HSP90 in group II endothelial cells – 51.22±14.57% (p=0.05). The activity of HSP90α protein in optic neuroglia cells was characterized by a gradual increase in the duration of the experiment and was higher by 12, 4 % in experimental group III (81.77±21.67 %) compared with control (71.66±4.95 %). Conclusions. Our study provides an insight into the significant difference in the immunoreactivity of heat shock proteins of the HSP70 and HSP90α families in neuroglia and endothelial cells of the optic nerve capillaries under the influence of Cr(VI). The results obtained suggest that Cr (VI) has a neurotoxic effect on the optic nerve with the development of edema, which is manifested by the thickening of nerve fibers. A comparison of the dynamics of the development of the dystrophic process in the optic nerve with the results of the immunohistochemical analysis showed, that an increase in the thickness of nerve fibers is accompanied by an increase in immunoreactive neuroglial cells (HSP90α) and endothelial cells (HSP70).","PeriodicalId":30651,"journal":{"name":"ScienceRise","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42528411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}