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Oxidative stress in the progression of Chronic Kidney Diseases in children 氧化应激在儿童慢性肾脏疾病进展中的作用
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.05
A. Ciuntu, J. Bernic, Tatiana Băluțel
{"title":"Oxidative stress in the progression of Chronic Kidney Diseases in children","authors":"A. Ciuntu, J. Bernic, Tatiana Băluțel","doi":"10.52673/18570461.22.4-67.05","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.05","url":null,"abstract":"Current studies show that the increase in the incidence of Chronic Kidney Disease cannot be fully explained only by risk factors well elucidated in the specialty literature, as knowing that oxidative stress is prevalent in Chronic Kidney Disease patients and is considered to be an important pathogenetic mechanism. Reactive oxygen species, which appear in excess as a result of ischemic, toxic or immune mediator changes, can negatively influence various pathological processes in renal pathology. These processes mainly refer to the pathogenesis of Chronic Kidney Disease or acute kidney injury. There are at least two pathophysiological mechanisms by which oxidative stress is formed in renal pathology, and then their damaging effects can cause, maintain or aggravate the cause of the condition. Following the initiation of inflammatory processes, the progression of renal damage is accelerated, with the eventual damage to all nephron structures as well as the interstitial space. The main sources of reactive oxygen species are mitochondria, but other cellular organelles may also be involved. Oxidant radicals produce oxidation of proteins, lipids, modification of nucleic acids with destruction of cell membranes, induction of apoptosis and lysis of kidney tissue. It is shown that free radicals are normally annihilated by superoxide dismutase – the antioxidant enzyme. There are several biomarkers that can be evaluated to detect oxidative stress and antioxidant status in patients with chronic kidney disease. Their determination in the context of a complex examination represents an informational support in the elucidation of pathogenetic mechanisms with the implementation of non-invasive early diagnosis methods. We reviewed the Chronic Kidney Disease literature to see if the guidelines and data are reliable enough to justify a particular approach.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75612786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cantemirian works in the community of Saint Paisie from the Neamt monastery Cantemirian在Neamt修道院的Saint Paisie社区工作
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.09
Andrei Eşanu, V. Eşanu
{"title":"Cantemirian works in the community of Saint Paisie from the Neamt monastery","authors":"Andrei Eşanu, V. Eşanu","doi":"10.52673/18570461.22.4-67.09","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.09","url":null,"abstract":"The study shows that some of Dimitrie Cantemir’s works (Divan and Description of Moldavia) reached the Neamt monastery from Moldova between the 18th – the first half of the 19th century. Copies of the Divan ..., printed in Iasi in 1698, were part of the old library of the monastery, being read by monks in the Paisian and post-Pasian period (17631859). The Description of Moldavia was even more appreciated in Neamt, which, thanks to the efforts of the monks, saw the light of print in 1825, within the monastery’s printing house. Since a small part of the edition remained in Neamt, the most of it, thanks to the Neamt monks again, were sent to many ecclesiastical centers, libraries, and universities, in all the lands inhabited by Romanians, including Bessarabia.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74432788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Establishment and development of the stage dance: trends and particulars 舞台舞的建立与发展:趋势与特点
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.18
Snejana Apostol
{"title":"Establishment and development of the stage dance: trends and particulars","authors":"Snejana Apostol","doi":"10.52673/18570461.22.4-67.18","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.18","url":null,"abstract":"This article is dedicated to the retrospective analysis of the constitution and development of stage dance, starting with the appearance of the first works with reference to the art of dance and ending with the best-known contemporary studies in this regard. The emphasis is put on the specific premises and trends that have generated the development of stage dance. It extensively analyzes the evolution of stage dance from the perspective of modernity and postmodernity, including in the context of the Romanian area, highlighting the external and internal factors that determined the specificity of the development of national choreographic art. The article also addresses the dichotomic aspect in the constitution and development of stage dance. At the same time, the purpose of this article is to present the analytical framework of the most valuable works in the field of choreography.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89928634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Synthesis of new coordination compounds of some 3d metals bazed on N(4)-(ethyl acetate) thiosemicarbazones 2-formil and 2-acetyl pyridine. Antioxidative properties 基于N(4)-(乙酸乙酯)硫代氨基脲、2-甲酰基和2-乙酰吡啶的三维金属配位化合物的合成。抗氧化性质
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.02
Anna Rusnac, O. Garbuz, S. Şova, A. Gulea
{"title":"Synthesis of new coordination compounds of some 3d metals bazed on N(4)-(ethyl acetate) thiosemicarbazones 2-formil and 2-acetyl pyridine. Antioxidative properties","authors":"Anna Rusnac, O. Garbuz, S. Şova, A. Gulea","doi":"10.52673/18570461.22.4-67.02","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.02","url":null,"abstract":"The given work includes the description of methods for the synthesis of new coordinative combinations of Cu(II), Mn(II), Fe(III) Co(III), Ni(II) and Zn(II) with N(4)-(ethyl acetate) thiosemicarbazones of 2-formylpyridine and 2-acetylpyridine. The characterization of the newly synthesized compounds was carried out using 1H NMR, 13C NMR, FTIR spectroscopy, conductivity, and elemental analysis. In addition, the structures of N(4)-(ethyl acetate) thiosemicarbazide and N(4)-(ethyl acetate) thiosemicarbazone 2-acetylpyridine (HL2) were determined using single crystal X-ray diffraction. The antioxidant activity of coordinative combinations was studied and compared with that of free ligands. The most pronounced antioxidant properties are possessed by [Ni(L2)Cl], whose value of IC50=15,05 μM is three times higher than the IC50=46,76 μM of the non-coordinating ligand and about 2,5 times higher than the reference substances Rutin and Trolox.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73235449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving the company’s image through the use of an operational strategic image management framework 通过使用运营战略形象管理框架来改善公司形象
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.06
Iurie Malancea
{"title":"Improving the company’s image through the use of an operational strategic image management framework","authors":"Iurie Malancea","doi":"10.52673/18570461.22.4-67.06","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.06","url":null,"abstract":"In order to continuously improve the competitiveness of the enterprise through the use of non-tangible assets, the paper discusses and proposes an operational framework for the strategic image management, which comprises three levels and is based on four steps aimed at strengthening and improving the company’s image so that the enterprise’s non-tangible assets serve as a source of sustainable competitive advantage. By going through all the stages, beginning with determining and defining the company’s identity and ending with its continuous improvement, the image of the company is enhanced, strengthened, and communicated in a way that gives it both short and long-term competitive advantages.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84852303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oenological potential of local and new selection grape varieties 本地和新选种葡萄的酿酒潜力
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.07
N. Taran, B. Morari, O. Soldatenco, Irina Ponomoriova, S. Nemteanu, B. Gaina, Crina Vicol
{"title":"Oenological potential of local and new selection grape varieties","authors":"N. Taran, B. Morari, O. Soldatenco, Irina Ponomoriova, S. Nemteanu, B. Gaina, Crina Vicol","doi":"10.52673/18570461.22.4-67.07","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.07","url":null,"abstract":"Currently, in the Republic of Moldova the assortment of red wine grape varieties is dominated by the classic French varieties. In recent decades, however, there has been a growing interest in red wines produced from local varieties. This research shows the oenological potential of the local red wine grape varieties Negru de Causeni and Copceac and the new selection variety Codrinschii, while the local grape variety Feteasca Neagra was selected as a control one. The dynamics of the maceration-fermentation process and the accumulation of the phenolic complex and the oenological potential of the produced dry red wines were studied. Physical-chemical indices of the experimental red wines were identified, including organic acids, phenolic complex, and monomeric anthocyanins content. The research allowed to establish the prospect of producing dry red wines rich in phenolic and coloring substances from Copceac and Codrinschii grape varieties.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85241409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Collective mentalities of the nobility in Bessarabia in the second half of the 19th century 19世纪下半叶比萨拉比亚贵族的集体心态
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.10
C. Gherasim
{"title":"Collective mentalities of the nobility in Bessarabia in the second half of the 19th century","authors":"C. Gherasim","doi":"10.52673/18570461.22.4-67.10","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.10","url":null,"abstract":"The change of mentality is a lasting process, carried out in special political, socio-economic and cultural conditions. In this sense, the influence of the tsarist domination regime, through all the policies promoted in the area between the Prut and the Dniester Rivers, generated some changes in the environment of the Bessarabian population in the second half of the 19th century, especially in the environment of the elites. The phenomenon is part of the general spirit of the 19th century, when the modernization and secularization of societies was fully affirmed, and with it the change of spiritual and cultural priorities. Keywords: nobility, Bessarabia, tsarist","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74882309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modernisation and the paradox of right and rights 现代化与权利与权利的悖论
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.08
R. Ciobanu
{"title":"Modernisation and the paradox of right and rights","authors":"R. Ciobanu","doi":"10.52673/18570461.22.4-67.08","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.08","url":null,"abstract":"The research behind this paper has been directed towards identifying the governance mechanisms focused on the protection of the human rights, being accompanied by studies that have defined states and processes occurring in societies that are increasingly interconnected. Several stages are shown when referring to these studies: identification of the demands made by citizens towards institutions and authorities; definition of the government’s perspective on the issues of the citizens and the society; determination of solutions so that in the Republic of Moldova the transition to a modernized society occurs, in which rights and freedoms are protected. As a result, there have been identified several problems not only of conjunctural nature (such as the pandemic crisis and the war in the region, presented in the paper as a case study), which constitute impediments to the development of the Republic of Moldova, but also deeper problems rooted in society, such as lack of trust, lack of will, lack of integrity, lack of efficiency of legal institutions etc. All these have generated a paradoxical state of law and legal institutions. Thus, the article examines the combined analysis of the modernization-crisis-law concepts through theoretical and methodological incursions that make the individual-collective connection, highlighting the way modernization is seen in the Republic of Moldova and indicating the need to review the role of law in the society.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"146 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78575622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stability of the metrological characteristics of the mass comparator HRP 200.4Y.KO 质量比较器HRP 200.04 . ko计量特性的稳定性
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.03
Anna Sabadaș, Alexei Pianîh, Alexandru Braguta, Victor Grușca
{"title":"Stability of the metrological characteristics of the mass comparator HRP 200.4Y.KO","authors":"Anna Sabadaș, Alexei Pianîh, Alexandru Braguta, Victor Grușca","doi":"10.52673/18570461.22.4-67.03","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.03","url":null,"abstract":"The metrological characteristics of the measuring devices are the characteristics that refer to the behavior of the measuring device in relation to the object under measurement, the environment and the human operator. Thus, having the same conditions in the laboratory and a well-trained and competent staff, the stability of the metrological characteristics of the mass comparator is studied in order to demonstrate its stability over time and provide increased confidence to subsequent beneficiaries. The actual measurements were carried out over a period of one year under the same conditions, their results proving that the mass comparator HRP 200.4Y.KO is capable of ensuring the traceability of the measurement unit.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88349392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mihail Statnii: through traditions towards the universal art 米哈伊尔·斯塔尼:通过传统走向普遍艺术
Akademos Revista de Stiinta Inovare Cultura si Arta Pub Date : 2023-03-01 DOI: 10.52673/18570461.22.4-67.21
Tudor Stăvilă
{"title":"Mihail Statnii: through traditions towards the universal art","authors":"Tudor Stăvilă","doi":"10.52673/18570461.22.4-67.21","DOIUrl":"https://doi.org/10.52673/18570461.22.4-67.21","url":null,"abstract":"The native village in the north of Moldova where Mihail Statnîi was born – Beleavinț, Briceni, with a predominantly Ukrainian population, with spectacular traditions preserved from his ancestors, has profoundly marked his artistic destiny. Few of our artists have approached with such consistency and dedication the themes of rustic life, traditional winter celebrations, wedding customs, carpet weaving etc. The velvety coloring and the resonant decoration of his paintings express the charming Bucovina, but also the universe of the childhood, the native village, the myths and legends of these lands. It is significant that Mihail Statnîi named his jubilee exhibition, which was held on the occasion of his 80th birthday, after the unfailing source of his inspiration – Traditions.","PeriodicalId":30644,"journal":{"name":"Akademos Revista de Stiinta Inovare Cultura si Arta","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82535300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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