JRSM Cardiovascular Disease最新文献

{"title":"Pharmaceutical intervention after evaluation of the risk of ictus in elderly patients institutionalized with atrial fibrillation.","authors":"Alberto Frutos Pérez-Surio,&nbsp;Roberto Lozano Ortiz,&nbsp;Alejandro Martínez Crespo","doi":"10.1177/2048004019848273","DOIUrl":"https://doi.org/10.1177/2048004019848273","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the risk of having a stroke and the risk of bleeding in institutionalized patients with atrial fibrillation. Atrial fibrillation is a common cardiac arrhythmia associated with increased morbidity and mortality. It is necessary to develop pharmacotherapy plans to minimize the risk.</p><p><strong>Design: </strong>A prospective study.</p><p><strong>Setting: </strong>Institutionalized patients.</p><p><strong>Participants: </strong>Inclusion criteria were: patients diagnosed with atrial fibrillation, with or without treatment for the prevention of stroke.</p><p><strong>Main outcome measures: </strong>The evaluation of the CHA2DS2-VASc criteria was performed. The risk of hemorrhage was assessed using the HAS-BLED scale, based on the risk factors associated with the probability of bleeding.</p><p><strong>Results: </strong>We included 53 patients (86.4 ± 6.4 years, 30.2% men). Of these, 37 (69.8%) were correctly anticoagulated. Of the remaining, 5 patients (31.2%) did not have any type of anticoagulant or antiaggregant treatment and 11 (68.7%) were treated with antiaggregant alone. The pharmaceutical intervention was performed in patients who did not meet stroke criteria. Of the untreated patients: two died before the intervention, two were recommended to be referred to cardiology and in one there was no intervention because of very advanced age. In the antiaggregant patients, it was decided not to modify the treatment. The reasons were: high risk of bleeding, very advanced age, advanced dementia or terminal illness, moderate risk of stroke, and clotting factor deficiency.</p><p><strong>Conclusions: </strong>The risk of stroke in elderly patients with atrial fibrillation is high, so it is important to control the risk factors.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019848273"},"PeriodicalIF":1.6,"publicationDate":"2019-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019848273","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37075036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of aortic ¹⁸F-NaF tracer uptake using PET/CT as a predictor of aortic calcification in postmenopausal women: A longitudinal study.","authors":"Marina Cecelja,&nbsp;Amelia Moore,&nbsp;Ignac Fogelman,&nbsp;Michelle L Frost,&nbsp;Glen M Blake,&nbsp;Phil Chowienczyk","doi":"10.1177/2048004019848870","DOIUrl":"https://doi.org/10.1177/2048004019848870","url":null,"abstract":"<p><strong>Introduction: </strong>Aortic calcification as detected by computed tomography is associated with arterial stiffening and is an important predictor of cardiovascular morbidity and mortality. Uptake of ¹⁸F-sodium fluoride (¹⁸F-NaF) in the aortic wall reflects metabolically active areas of calcification. The aim of this study was to determine if ¹⁸F-NaF uptake in the aorta is associated with calcification and progression of calcification as detected by computed tomography.</p><p><strong>Methods: </strong>Twenty-one postmenopausal women (mean age 62 ± 6 years) underwent assessment of aortic ¹⁸F-NaF uptake using positron emission tomography/computer tomography at baseline and a repeat computed tomography scan after a mean follow-up of 3.8 ± 1.3 years. Tracer uptake was quantified by calculating the target-to-background (TBR) ratios at baseline and follow-up. Calcification was assessed at baseline and follow-up using computed tomography.</p><p><strong>Results: </strong>Over the follow-up period, aortic calcium volume increased from 0.46 ± 0.62 to 0.71 ± 0.93 cm³ (<i>P</i> < 0.05). However, the change in calcium volume did not correlate with baseline TBR either unadjusted (<i>r</i> = 0.00, <i>P</i> = 1.00) or adjusted for age and baseline calcium volume (beta coefficient = -0.18, <i>P</i> = 0.42). TBR at baseline did not differ between participants with (<i>n</i> = 16) compared to those without (<i>n</i> = 5) progression in calcium volume (2.43 ± 0.46 vs. 2.31 ± 0.38, <i>P</i> = 0.58). In aortic segments identified to have the highest tracer uptake at baseline, calcium volume did not significantly change over the follow-up period (<i>P</i> = 0.41).</p><p><strong>Conclusion: </strong>In a cohort of postmenopausal women, ¹⁸F-NaF uptake as measured by TBR in the lumbar aorta did not predict progression of aortic calcification as detected by computed tomography over a four-year follow-up.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019848870"},"PeriodicalIF":1.6,"publicationDate":"2019-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019848870","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37253123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of EndoAnchors in endovascular repair of abdominal aortic aneurysms with challenging proximal neck: Single-centre experience.","authors":"Rocco Giudice,&nbsp;Ottavia Borghese,&nbsp;Giorgio Sbenaglia,&nbsp;Carlo Coscarella,&nbsp;Claudia De Gregorio,&nbsp;Marco Leopardi,&nbsp;Gabriele Pogany","doi":"10.1177/2048004019845508","DOIUrl":"https://doi.org/10.1177/2048004019845508","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this study was to present a single-centre experience with EndoAnchors in patients who underwent endovascular repair for abdominal aortic aneurysms with challenging proximal neck, both in the prevention and treatment of endograft migration and type Ia endoleaks.</p><p><strong>Methods: </strong>We retrospectively analysed 17 consecutive patients treated with EndoAnchors between June 2015 and May 2018 at our institution. EndoAnchors were applied during the initial endovascular aneurysm repair procedure (primary implant) to prevent proximal neck complications in difficult anatomies (nine patients), and in the follow-up after aneurysm exclusion (secondary implant) to correct type Ia endoleak and/or stent-graft migration (eight patients).</p><p><strong>Results: </strong>Mean time for anchors implant was 23 min (range 12-41), with a mean of 5 EndoAnchors deployed per patient. Six patients in the secondary implant group required a proximal cuff due to stent-graft migration ≥10 mm. Technical success was achieved in all cases, with no complications related to deployment of the anchors. At a median follow-up of 13 months (range 4-39, interquartile range 9-20), there were no aneurysm-related deaths or aneurysm ruptures, and all patients were free from reinterventions. CT-scan surveillance showed no evidence of type Ia endoleak, anchors dislodgement or stent-graft migration, with a mean reduction of aneurysm diameter of 0.4 mm (range 0-19); there was no sac growth or aortic neck enlargement in any case.</p><p><strong>Conclusions: </strong>EndoAnchors can be safely used in the prevention and treatment of type Ia endoleaks in patients with challenging aortic necks, with good results in terms of sac exclusion and diameter reduction in the mid-term follow-up.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019845508"},"PeriodicalIF":1.6,"publicationDate":"2019-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019845508","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37199196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Susac syndrome presenting with acute hemibody paraesthesia.","authors":"Philip Campbell,&nbsp;Diego Kaski,&nbsp;Tabish A Saifee","doi":"10.1177/2048004019844687","DOIUrl":"https://doi.org/10.1177/2048004019844687","url":null,"abstract":"<p><p>Susac syndrome is an orphan disease characterised by encephalopathy, branch retinal artery occlusion and sensorineural hearing loss. As the clinical triad is rarely present at symptom onset, it is often initially misdiagnosed and appropriate treatment is often delayed. Herewith, we report a case of Susac syndrome in a 47-year-old man presenting with acute hemisensory loss and highlight the challenges of early diagnosis, particularly relevant in the era of hyperacute stroke management.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019844687"},"PeriodicalIF":1.6,"publicationDate":"2019-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019844687","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37198157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right atrial myxoma presenting as a pulmonary embolism in a 32-year-old female.","authors":"Amitabh C Pandey,&nbsp;John J Carey,&nbsp;Jess L Thompson","doi":"10.1177/2048004018817606","DOIUrl":"https://doi.org/10.1177/2048004018817606","url":null,"abstract":"<p><p>Primary cardiac tumors are typically benign, with myxomas being most common. We present a 32-year-old female with a chief complaint of dyspnea and a constant non-radiating chest pressure along the left sternal border. She was found to have a pulmonary embolism that was ultimately caused by embolization of a right atrial myxoma with remnants of a large, highly mobile mass attached to the right inter-atrial septum prolapsing through the tricuspid valve. The patient underwent a median sternotomy, right atrial mass resection, pulmonary embolectomy, and inter-atrial septum reconstruction using the patient's pericardium. The importance of finding the etiology of initial diagnoses is stressed with long-term outcomes for patients.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004018817606"},"PeriodicalIF":1.6,"publicationDate":"2019-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004018817606","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37358500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low Walking Impairment Questionnaire score after a recent myocardial infarction identifies patients with polyvascular disease.","authors":"Birgitta Jönelid,&nbsp;Björn Kragsterman,&nbsp;Lars Berglund,&nbsp;Bertil Andrén,&nbsp;Nina Johnston,&nbsp;Bertil Lindahl,&nbsp;Jonas Oldgren,&nbsp;Christina Christersson","doi":"10.1177/2048004019841971","DOIUrl":"https://doi.org/10.1177/2048004019841971","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate whether the Walking Impairment Questionnaire score could identify patients with polyvascular disease in a population with recent myocardial infarction and their association with cardiovascular events during two-year follow-up.</p><p><strong>Design: </strong>A prospective observational study.</p><p><strong>Setting: </strong>Patients admitted to the acute coronary care unit, the Department of Cardiology, Uppsala University Hospital.</p><p><strong>Participants: </strong>Patients admitted with acute Non-STEMI- or STEMI-elevation myocardial infarction.</p><p><strong>Main outcome measures: </strong>The Walking Impairment Questionnaire, developed as a self-administered instrument to assess <i>walking distance</i>, <i>speed</i>, and <i>stair climbing</i> in patients with peripheral artery disease, predicts future cardiovascular events and mortality. Two hundred and sixty-three patients with recent myocardial infarction answered Walking Impairment Questionnaire. Polyvascular disease was defined as abnormal findings in the coronary- and carotid arteries and an abnormal ankle-brachial index. The calculated score for each of all three categories were divided into quartiles with the lowest score in first quartile.</p><p><strong>Results: </strong>The lowest (worst) quartile in all three Walking Impairment Questionnaire categories was associated with polyvascular disease, fully adjusted; <i>distance</i>, odds ratio (OR) 5.4 (95% confidence interval (CI) 1.8-16.1); <i>speed</i>, OR 7.4 (95% CI 1.5-36.5); <i>stair climbing</i>, OR 8.4 (95% CI 1.0-73.6). In <i>stair climbing score</i>, patients with the lowest (worst) score had a higher risk for the composite cardiovascular endpoint compared to the highest (best) score; hazard ratio 5.3 (95% CI 1.5-19.0). The adherence to medical treatment was high (between 81.7% and 99.2%).</p><p><strong>Conclusions: </strong>The Walking Impairment Questionnaire is a simple tool to identify myocardial infarction patients with more widespread atherosclerotic disease and although well treated medically, stair climbing predicts cardiovascular events.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019841971"},"PeriodicalIF":1.6,"publicationDate":"2019-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019841971","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37358502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endothelial dysfunction and heart failure: A review of the existing bibliography with emphasis on flow mediated dilation.","authors":"Sofia Giannitsi,&nbsp;Maria Bougiakli,&nbsp;Aris Bechlioulis,&nbsp;Katerina Naka","doi":"10.1177/2048004019843047","DOIUrl":"https://doi.org/10.1177/2048004019843047","url":null,"abstract":"<p><p>Heart failure affects 1-2% of the population worldwide, and it is characterized by episodes of decompensation often requiring hospitalization. Although targeted treatment has reduced the prevalence of rehospitalizations to 30-50%, mortality rates remain high. A complex blend of structural and functional alterations accounts for the genesis and progression of heart failure, but the exact underlying pathophysiology remains poorly understood. The aim of this review is to summarize endothelial dysfunction and its role in the pathogenesis and progression of heart failure. Moreover, it sums up all the appropriate methods of assessing endothelial dysfunction emphasizing on flow-mediated dilation and introduces endothelium as a potential target for new therapeutic development and research in the wide spectrum of the syndrome called heart failure.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019843047"},"PeriodicalIF":1.6,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019843047","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37171830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"False activation of the cardiac catheterization laboratory: The price to pay for shorter treatment delay.","authors":"George Degheim,&nbsp;Abeer Berry,&nbsp;Marcel Zughaib","doi":"10.1177/2048004019836365","DOIUrl":"https://doi.org/10.1177/2048004019836365","url":null,"abstract":"<p><strong>Introduction: </strong>In patients with acute ST elevation myocardial ischemia (STEMI), national efforts have focused on reducing door-to-balloon (D2B) times for primary percutaneous coronary intervention (PCI). This emphasis on time-to-treatment may increase the rate of inappropriate cardiac catheterization laboratory (CCL) activations and unnecessary healthcare utilization. To achieve lower D2B times, community hospitals and EMS systems have enabled emergency medical technicians (EMTs) and emergency department (ED) physicians to activate the CCLs without immediately consulting a cardiologist.</p><p><strong>Objective: </strong>The purpose of this study is to determine the rate and main causes of inappropriate activation of the CCL which will aid in finding solutions to reduce this occurrence.</p><p><strong>Method: </strong>This is a retrospective study, based on an electronic medical system review of all inappropriate CCL activation who presented to Providence Hospital and Medical Centers (PHMC) in Michigan, from January 2015 to July 2016.</p><p><strong>Results: </strong>The CCL was activated 375 times for suspected STEMI. The false STEMI activation was identified in 47 patients which represents 12.5% of total CCL activation. The vast majority of this false activation was due to non-diagnostic electrocardiogram (ECG) that did not meet the STEMI criteria.</p><p><strong>Conclusion: </strong>The subjective interpretation of the ECG by EMTs and ED physicians tend to show a wide variability, which may lead to higher-than-anticipated false activation rates of up to 36% in one study. Some studies had reported that up to 72% of inappropriate activations were caused by ECG misinterpretations. These false activations have ramifications that lead to both clinical and financial costs.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019836365"},"PeriodicalIF":1.6,"publicationDate":"2019-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019836365","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37171827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of direct oral anticoagulants on the resolution of left ventricular thrombus-A case series and literature review.","authors":"Reem A Bahmaid,&nbsp;Shoroq Ammar,&nbsp;Sarah Al-Subaie,&nbsp;Mohammed A Soofi,&nbsp;Hassan Mhish,&nbsp;Madonna Ali Yahia","doi":"10.1177/2048004019839548","DOIUrl":"https://doi.org/10.1177/2048004019839548","url":null,"abstract":"<p><strong>Background: </strong>Left ventricular thrombus is a frequent complication of acute myocardial infarction and a risk factor for thromboembolic complications. Warfarin has been frequently used, but has some disadvantages that limit its use. Direct oral anticoagulants, in particular Dabigatran and Rivaroxaban have been proved to be effective in preventing thromboembolism among patients with non-valvular atrial fibrillation. However, no randomized clinical trials testing the efficacy and safety of these agents in patients with existing left ventricular thrombus. Furthermore, direct oral anticoagulants are still not approved by the Food and Drug Administration in the management of left ventricular thrombus.</p><p><strong>Method: </strong>This study was a retrospective cohort assessing the efficacy of direct oral anticoagulants (Dabigatran or Rivaroxaban) on the resolution of left ventricular thrombus in patients taking either of these drugs during the study period from December, 2011 to December, 2016 at King Fahad Medical City. All patients' records were reviewed and all patients who were diagnosed with left ventricular thrombus were included. Patients without available echocardiogram records were excluded. The study was approved by the institutional review board of King Fahad medical city, Riyadh Saudi Arabia.</p><p><strong>Result: </strong>During the defined study period we found that 413 and 1218 patients were taking Dabigatran and Rivaroxaban, respectively. After filtering them based on the specialty of the prescriber, we ended up with 299 patients who have been started on Dabigatran and 448 patients who have been started on Rivaroxaban by cardiologists. Moreover, after reviewing echocardiogram reports for all of them (747 patients), we found that 11 patients were diagnosed to have left ventricular thrombus. Among those 11 patients, seven of them were treated with direct oral anticoagulants from the beginning and the remaining four patients were shifted from Warfarin to direct oral anticoagulants. All of them (7 patients) showed left ventricular thrombus resolution on follow-up echocardiogram.</p><p><strong>Conclusion: </strong>Use of direct oral anticoagulants showed promising results in the resolution of left ventricular thrombus in patients diagnosed with left ventricular thrombus. Further studies at multiple health care centers are needed to further evaluate the efficacy and safety of direct oral anticoagulants as compared to traditional treatment in patients with left ventricular thrombus.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019839548"},"PeriodicalIF":1.6,"publicationDate":"2019-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019839548","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37170883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient outcomes in GuideLiner facilitated percutaneous coronary intervention stratified by the SYNTAX score: A retrospective analysis.","authors":"Shuangbo Liu,&nbsp;Christopher Parr,&nbsp;Hannah Zhang,&nbsp;Basem Elbarouni,&nbsp;Ashish Shah,&nbsp;Malek Kass,&nbsp;Amir Ravandi","doi":"10.1177/2048004019835449","DOIUrl":"https://doi.org/10.1177/2048004019835449","url":null,"abstract":"<p><strong>Objectives: </strong>To determine patient outcomes in GuideLiner facilitated percutaneous coronary intervention stratified by the SYNTAX score.</p><p><strong>Design: </strong>Single centre retrospective cohort analysis.</p><p><strong>Participants: </strong>A total of 540 consecutive cases facilitated by GuideLiner at a single center.</p><p><strong>Main outcome measures: </strong>Successful stent delivery, in-hospital, 30 day and 1 year mortality rates stratified by SYNTAX score.</p><p><strong>Results: </strong>The most common indication for GuideLiner was need for increased support for balloon or stent delivery (82%), 6% for non-coaxial guide, 9% for chronic total occlusion and 3% for selective vessel engagement. Successful stent delivery was achieved in 91% of all cases, with no complications occurred due to GuideLiner use. In-hospital, 30 day and 1 year mortality rates were 2.8%, 2.1% and 4.5%, respectively. The high SYNTAX group was associated with higher rates of initial TIMI score of 0-1; however, the final TIMI score rate of successful delivery and complications did not differ between groups. In-hospital and 1 year mortality rates were higher in the higher SYNTAX groups.</p><p><strong>Conclusions: </strong>The GuideLiner is an easy to use guide catheter extension system with high rates of success and low rates of complications, across all SYNTAX groups.</p>","PeriodicalId":30457,"journal":{"name":"JRSM Cardiovascular Disease","volume":"8 ","pages":"2048004019835449"},"PeriodicalIF":1.6,"publicationDate":"2019-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2048004019835449","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37093501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}