IEEE Ultrasonics Symposium, 2005.最新文献_第4页

On the oscillations of microbubbles in tubes with diameters as small as 12 microns 在直径小至12微米的管中微泡的振荡

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1602984

C. Caskey, D. Kruse, P. Dayton, K. Ferrara

{"title":"On the oscillations of microbubbles in tubes with diameters as small as 12 microns","authors":"C. Caskey, D. Kruse, P. Dayton, K. Ferrara","doi":"10.1109/ULTSYM.2005.1602984","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1602984","url":null,"abstract":"In recent years, experiments coupled with mathematical models have been used to predict microbubble oscillation. Theoretical investigations of ultrasonically driven microbubble behavior are based on the Rayleigh-Plesset equation and assume that the oscillating microbubble is symmetric and in an infinite fluid. The present study shows that constrained microbubble activity in a tube with a diameter on the same order of magnitude as the microbubble diameter differs from previous investigations that assume an infinite fluid. In the microvessel phantoms used in our study, microbubbles expand less in vessels with a diameter of 12 μm than in vessel phantoms with a diameter of 195 μm, with expansion in a 25-μm vessel shown to lie between that observed in the larger and smaller vessels. In the interest of exploring ultrasonic parameters that are relevant to current drug and gene delivery studies, experiments for relative expansion involve a transmission center frequency of 1 MHz with a peak negative pressure (PNP) of 1.4 MPa. Radiation force is also demonstrated following transmission with a center frequency of 5 MHz. Keywords-contrast ultrasound; microbubble; drug delivery; gene therapy","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122154454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

New developments in tissue-type imaging (TTI) of prostate cancer: combined ultrasonic and magnetic-resonance methods 前列腺癌组织型成像(TTI)的新进展:超声与磁共振联合成像方法

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1602978

E. Feleppa, S. Dasgupta, A. Kalisz, J. Ketterling, S. Ramachandran, C. Porter, M. Lacrampe, D. Dail, D. Sparks, F. Arias-Mendosa

{"title":"New developments in tissue-type imaging (TTI) of prostate cancer: combined ultrasonic and magnetic-resonance methods","authors":"E. Feleppa, S. Dasgupta, A. Kalisz, J. Ketterling, S. Ramachandran, C. Porter, M. Lacrampe, D. Dail, D. Sparks, F. Arias-Mendosa","doi":"10.1109/ULTSYM.2005.1602978","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1602978","url":null,"abstract":"Because current methods of imaging prostate cancer are inadequate, biopsies cannot be guided effectively and treatment cannot be planned, targeted or monitored optimally. Therefore, our research is aimed at ultrasonically characterizing cancerous prostate tissue so that we can image it more effectively and thereby provide improved means of detecting, treating, and monitoring prostate cancer. We base our characterization methods on spectrum analysis of radiofrequency (RF) ultrasonic (US) echo signals combined with clinical variables such as prostate-specific antigen (PSA). We classify parameters of US spectra (USS) using artificial neural networks (ANNs), and express classification efficacy using relative-operating- characteristic (ROC) methods. The US methods produce ROC- curve areas of 0.84 compared to 0.64 for conventional methods. We generate lookup tables (LUTs) that translate spectral parameters and clinical variables directly to pixel values in tissue-type images (TTIs) that show cancerous regions in 2- or 3- D. Based on encouraging results obtained by others using magnetic-resonance spectroscopy (MRS) for identifying cancerous prostate lesions, we are investigating means of combining MRS with USS methods to produce multimodality TTIs.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"166 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122162214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Trapping of low sensitivity object by seed bubbles 用种子气泡捕获低灵敏度物体

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1602784

Y. Yamakoshi

{"title":"Trapping of low sensitivity object by seed bubbles","authors":"Y. Yamakoshi","doi":"10.1109/ULTSYM.2005.1602784","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1602784","url":null,"abstract":"Recently, many kinds of micro bubbles have been developed for ultrasonic wave contrast agents. Some bubbles have hard biopolymer shells in order to prevent internal gas diffusion. Another bubble is equipped with multiple shells to give some functions to the bubble. However, these developments usually harden the bubbles decreasing volumetric oscillation under ultrasonic wave radiation. The Bjerknes force, which is driving force in micro bubble trapping by ultrasonic wave, is proportional to the volumetric oscillation, the received force is often too small to manipulate the bubbles. In sonoporation, which is a sophisticated method in dose improvement, it is expected that the micro bubbles explode as a result of large volumetric oscillation. In this paper, a novel method of micro objects trapping by seed bubbles is proposed. The seed bubbles trap the target objects by spatially restricted Bjerknes force, which is generated by secondary ultrasonic waves radiated from the oscillating seed bubbles. The produced target objects-seed bubbles complex may play an important role in sonoporation, because the seed bubbles, which are easy to explode by high intensity ultrasonic wave, exist close to the payloads of the target objects.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129576685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Finite element analysis of monolithic filters 单片滤波器的有限元分析

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1603064

M.S. Patel, Y. Yong, M. Tanaka

引用次数: 0

Single-chip multiple-frequency RF microresonators based on aluminum nitride contour-mode and FBAR technologies 基于氮化铝轮廓模和FBAR技术的单片多频射频微谐振器

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1603063

G. Piazza, P. Stephanou, J. Black, R. White, A. Pisano

引用次数: 17

Small percent bandwidth design of a 423-MHz notch-coupled micromechanical mixler 423 mhz陷波耦合微机械混频器的小百分比带宽设计

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1603090

Sheng-Shian Li, Yu-Wei Lin, Yuan Xie, Z. Ren, C. Nguyen

引用次数: 14

Ionic conductivity in acoustic crystals 声学晶体中的离子电导率

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1602884

E. Charnaya, A. L. Pirozerskiĭ, C. Tien

引用次数: 0

Transient ultrasound elastography for breast cancer diagnosis using impulsive radiation force: an in vitro study 瞬态超声弹性成像用于脉冲辐射力诊断乳腺癌的体外研究

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1603109

D. Melodelima, J. Bamber, F. Duck, J. Shipley

{"title":"Transient ultrasound elastography for breast cancer diagnosis using impulsive radiation force: an in vitro study","authors":"D. Melodelima, J. Bamber, F. Duck, J. Shipley","doi":"10.1109/ULTSYM.2005.1603109","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1603109","url":null,"abstract":"The use of impulsive acoustic radiation force for strain imaging was investigated. A focused ultrasound transducer was used to apply localised radiation force to a small volume of tissue mimic (100 mm 3 ) for durations of 8 ms. A conventional real-time ultrasound imaging probe was used to obtain echo signals. The resulting strains were mapped using ultrasound correlation-based methods. The instantaneous strain immediately following cessation of the radiation force was observed at depth within homogeneous gels and within stiff inclusions, and was seen to vary approximately linearly with the Young's modulus of the material. The highly localised and transient strain that is produced may permit the sensing of variations in tissue elastic properties that are difficult to detect with conventional elastography, due to greater independence from boundary conditions. For example, the characteristic, bi-directional, high strain artefacts due to stress concentration, often seen with static elastography at tissue-inclusion interfaces, do not appear using the transient radiation force strain imaging technique.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129346706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimation of pressure-distribution effects upon elasticity imaging 压力分布对弹性成像影响的估计

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1603207

T. Matsumura, R. Shinomura, T. Mitake, H. Kanda, M. Yamakawa, T. Shiina

{"title":"Estimation of pressure-distribution effects upon elasticity imaging","authors":"T. Matsumura, R. Shinomura, T. Mitake, H. Kanda, M. Yamakawa, T. Shiina","doi":"10.1109/ULTSYM.2005.1603207","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1603207","url":null,"abstract":"We have already proposed the real-time strain imaging techniques (ca. 12 fps) for stable diagnosis in freehand and image classification method for the breast tissue diagnosis. For the objective diagnosis, most important problem is come from the fact that the strain image patterns were strongly depending on the magnitude and uniformity of the compression. In this paper, we investigate the pressure-distribution effects on the elasticity imaging using the tissue-mimicking elastography phantoms. We prepared 5 types of elastography phantoms with different stiffness. Phantoms #1-#3 have uniform stiffness overall in the rectangular solids and #4-#5 include small rectangular solids with different stiffness from surroundings. The phantom stiffness was estimated from the distribution of pressure and induced strain using our elasticity imaging system as follows. (1) The Young's moduli of first three phantoms were estimated as 6±1 kPa, 27±4 kPa, and 108±23 kPa, respectively. (2) In the case of phantoms #4 and #5, outer parts were estimated as 6±1 kPa and 8±2 kPa, and inclusion parts were measured as 12±1 kPa and 58±14 kPa, respectively. (3) For the special case of above phantom #1, we applied non-uniform pressure (3 times difference between each lateral limits). Even in that case, we successfully reduced the effect of non-uniformity from 235 % to 5 % in elasticity imaging.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129931430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Cantilever resonance induced in situ by magnetostriction for active flow control 基于磁致伸缩的悬臂梁原位共振主动流量控制

IEEE Ultrasonics Symposium, 2005. Pub Date : 2005-09-18 DOI: 10.1109/ULTSYM.2005.1603343

O. Ducloux, N. Tiercelin, Y. Deblock, P. Pernod, V. Preobrazhensky, A. Merlen

{"title":"Cantilever resonance induced in situ by magnetostriction for active flow control","authors":"O. Ducloux, N. Tiercelin, Y. Deblock, P. Pernod, V. Preobrazhensky, A. Merlen","doi":"10.1109/ULTSYM.2005.1603343","DOIUrl":"https://doi.org/10.1109/ULTSYM.2005.1603343","url":null,"abstract":"Air flow separation can be actively controlled by blowing air jets through submillimetric holes on a surface. To achieve such pulsed jets, a microvalve composed of an internal resonant cantilever actuated by a magnetostrictive film was designed, fabricated and characterized. The microvalve is fed by a pressurized source of air and the resonating cantilever acts as a deflector on the internal fluid flow addressed alternatively to the output hole on the wing's surface or to a recycling output. Magnetostrictive films were chosen as actuating means for they can provide high induced stress compared to other kinds of active materials, and also because of their remote actuation capability. In this device, artificially nanostructured TbCo/FeCo multilayers were used,making possible the induction of a Spin Transition Reorientation (SRT) state in the layer. This technique increases dramatically the magnetoelastic sensitivity and make magnetostrictive actuation compatible with Microsystems: thus, the field produced by two microcoils is sufficient for the dynamic actuation. Characterization of the resonance frequency, amplitude and magnetoelastic coefficient are achieved by interferometric means. Outcoming flow is visualized by conventional strioscopy method using He / Air optical index difference. The design and fabrication process of the microsystem, and the results of these characterizations are presented in this paper.","PeriodicalId":302030,"journal":{"name":"IEEE Ultrasonics Symposium, 2005.","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126895919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3