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Swiss Archives of Neurology and Psychiatry最新文献

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[Promoting research in Swiss psychiatry]. [促进瑞士精神病学的研究]。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
C Buddeberg, C Wolf
{"title":"[Promoting research in Swiss psychiatry].","authors":"C Buddeberg,&nbsp;C Wolf","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There is a lack of junior scientists in the psychiatry of Switzerland since several years. The paper reports about an investigation of 135 residents and fellows of psychiatric university hospitals of the German speaking part of Switzerland. Results indicate that there is no continuous exchange of informations about projected, ongoing and finished research projects between researchers and clinicians. Residents and fellows are interested in being trained in research methodology and in discussions of actual studies carried out by experienced scientists. They appreciate participating in research projects. Finally some recommendations for the improvement of research promotion in the swiss psychiatry are discussed.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 4","pages":"23-5"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18540945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Production and function of IL-10 in the central nervous system. 中枢神经系统中IL-10的产生和功能。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
K Frei, H Lins, A Fontana
{"title":"Production and function of IL-10 in the central nervous system.","authors":"K Frei,&nbsp;H Lins,&nbsp;A Fontana","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Our data suggest an important regulatory role for IL-10 within the central nervous system by a) reducing the antigenpresenting capacity of astro- and microglia and thereby lowering or preventing, antigen-specific proliferative T cell responses, and b) inhibition of inflammatory cytokine production by the resident parenchymal cells as well as from infiltrating monocytes/macrophages. In the latter instance the signals triggering cytokine production are crucial since IL-10 interferes with bacterial but not viral or cytokine-induced activation of expression of cytokine genes.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 3","pages":"30-1"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18542509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of a computer-based attention retraining program for patients with multiple sclerosis. 基于计算机的多发性硬化症患者注意力再训练方案的评价。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
A Plohmann, L Kappos, H Brunnschweiler
{"title":"Evaluation of a computer-based attention retraining program for patients with multiple sclerosis.","authors":"A Plohmann,&nbsp;L Kappos,&nbsp;H Brunnschweiler","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 3","pages":"35-6"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18542511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Apomorphine as adjuvant treatment in idiopathic Parkinson syndrome]. [阿波啡辅助治疗特发性帕金森综合征]。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
M F Bösch, H P Ludin
{"title":"[Apomorphine as adjuvant treatment in idiopathic Parkinson syndrome].","authors":"M F Bösch,&nbsp;H P Ludin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>28 patients suffering from idiopathic Parkinson's disease received subcutaneous apomorphine for the treatment of painful dystonia and of off-phases of long duration. After a mean period of 12.4 months 20 patients still used apomorphine. In this time the mean dose per injection had fallen from 2.5 mg to 2.1 mg and the mean number of daily applications from 2.6 to 2.2. Most patients considered dystonias and off-phases to respond satisfactorily to apomorphine. However, in most cases the treatment effect was impaired by side effects, especially nausea.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 5","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18711577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short and longterm fluctuations of generational MS risk. 代际MS风险的短期和长期波动。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
V Ajdacic-Gross, M Schmid, A Tschopp, F Gutzwiller
{"title":"Short and longterm fluctuations of generational MS risk.","authors":"V Ajdacic-Gross,&nbsp;M Schmid,&nbsp;A Tschopp,&nbsp;F Gutzwiller","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>According to the hypothesis that childhood is an important age stage in view of MS predisposition, alterations of MS risk may be expected in respect of generational succession. Age-period-cohort-analysis in the appropriate statistical analysis model in this connection. After having shown considerable fluctuations of generational MS risk in the long term view we have tried to derive additional informations from corresponding short term fluctuations: descriptive informations as well as results in relation to the short term fluctuations of infectious diseases' mortality. While applying again age-period-cohort-analysis the results are questioned by the fact that the underlying cohort estimates represent 5-years-moving-averages. Computerized individual death records of the Swiss mortality statistics available since 1969 will enable us to check the recent results.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 3","pages":"33-4"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18542510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cardiac side effects and ECG changes with lamotrigine?--A clinical study]. 拉莫三嗪的心脏副作用和心电图改变?——一项临床研究]。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
B J Steinhoff, S R Stodieck, F P Tiecks, R Wedel, B Polatschek
{"title":"[Cardiac side effects and ECG changes with lamotrigine?--A clinical study].","authors":"B J Steinhoff,&nbsp;S R Stodieck,&nbsp;F P Tiecks,&nbsp;R Wedel,&nbsp;B Polatschek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After a patient treated with lamotrigine (LTG) had suffered from thoracal pain and repolarisation deficiencies in the electrocardiogram (ECG), we prospectively investigated 20 patients with localization-related epilepsies to assess cardiovascular side effects of LTG. During the study, LTG was added to a stable dosage of one to three first line antiepileptic drugs (AED). Physical examinations and ECG recordings were performed regularly. Clinical cardial side effects did not occur. Only in single ECG traces of six patients non specific abnormalities were seen. Only in one patient, the abnormalities (supraventricular extrasystoles and a first grade atrioventricular block) unequivocally appeared initially under LTG. However, in the same patient two later ECG recordings under higher LTG dosages were normal. The statistical analysis of the ventricular activation times did not reveal any significant changes under LTG (p = 0.05) with the exception of an extended PQ time when comparing a patient group before LTG (n = 11) with another patient group under LTG (n = 11). Since this observation was not confirmed by the statistical analysis of a third patient group (n = 10) with ECG data prior to and under LTG, we believe that the statistically significant changes mentioned above were based mainly on structural differences between the patient groups and not on true LTG effects. Our results do not give evidence for an elevated risk of clinically relevant cardial side effects under LTG.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 3","pages":"8-12"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18542513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurologic manifestations of Staphylococcus aureus infections. Analysis of 43 patients. 金黄色葡萄球菌感染的神经学表现。43例患者分析。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
F Schäfer, H P Mattle
{"title":"Neurologic manifestations of Staphylococcus aureus infections. Analysis of 43 patients.","authors":"F Schäfer,&nbsp;H P Mattle","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We present an analysis of the neurologic manifestations of Staphylococcus aureus infections in 43 patients. Half of the infections whose source could be identified were nosocomial. The spectrum of neurological sequelae included meningitis, solitary and multiple intracerebral and epidural abscesses, cerebral ischemia and hemorrhage, acute encephalopathies, subdural empyemas, spinal abscesses, and radicular compression syndromes. In the majority of patients the course was severe and protracted and relapses were frequent. Mortality was high (28%), even with early diagnosis and treatment; diabetes mellitus, alcohol abuse, and chronic renal failure were unfavorable prognostic factors. In patients with abscess formation early surgical drainage improved the outcome. However, often treatment was complicated by sequestration at inaccessible foci and secondary dissemination. Combined antibiotic therapy with flucloxacillin and chloramphenicol may be the most successful antibiotic regimen.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 1","pages":"25-9"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18533448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dance training and eating disorders]. [舞蹈训练和饮食失调]。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
M Archinard, U Scherer, N Reverdin, P Rouget, A F Allaz
{"title":"[Dance training and eating disorders].","authors":"M Archinard,&nbsp;U Scherer,&nbsp;N Reverdin,&nbsp;P Rouget,&nbsp;A F Allaz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Medical history, eating habits, weight, current symptomatology and EDI (Eating Disorders Inventory)-scores of 41 bulimic female patients with and without past training in dancing, who came for treatment to an outpatient clinic, were compared. It was found that both groups of patients were not different for age, age at beginning of bulimia, actual as well as minimal and maximal BMI (Body mass index), length and severity of symptomatology, frequency of bulimic behaviors, and scores on the subscales of the EDI, but it should be noted that these similarities might be in relationship with some methodological shortcomings. Considering the prevalence of bulimia nervosa in women and the high frequency of ballet and sports training in teenagers, some hypotheses about the possible influence of strenuous physical exercise in childhood on the symptomatology and some psychological traits in adults with anorexia nervosa, bulimia nervosa, or binge-eating disorder are presented. Further studies, including standardized scales and larger samples, are necessary.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 2","pages":"23-7"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18533452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Functional somatic complaints in the emergency service and 4 year outcome]. [急诊服务中的功能性躯体主诉和4年预后]。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
M De Clercq, B Gillain, P Meert, P Hoyois
{"title":"[Functional somatic complaints in the emergency service and 4 year outcome].","authors":"M De Clercq,&nbsp;B Gillain,&nbsp;P Meert,&nbsp;P Hoyois","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article presents the clinical profile of 72 somatizations taking in charge by a psychiatric team in a emergency room. They represent mood disorders (37.5%), psychotic disorders (11%) and anxiety disorders (20%). The psychiatric antecedents are very poor. Their outcome after 4 years is good on the health sickness rating scale of Luborsky in 35% and very bad in 25%, particularly for symptomatic score. After their taking in charge in the emergency room, these patients go not much in psychiatric hospitals and in psychiatric consultations. This observation gives to this first intervention in the emergency room a very important rule.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 4","pages":"5-11"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18541955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Psychiatric changes caused by epileptic seizures]. [癫痫发作引起的精神变化]。
Swiss Archives of Neurology and Psychiatry Pub Date : 1994-01-01
W Fröscher, K D Neher
{"title":"[Psychiatric changes caused by epileptic seizures].","authors":"W Fröscher,&nbsp;K D Neher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Frequent tonic-clonic seizures could probably lead to psychic disorders. In various studies a decrease in at least single functions of mental capability was found depending on the frequency of the seizures and/or the duration and/or the age of onset of the disease. The development of neuropsychological deficits depends on the type of seizures. Particularly BNS-seizures and the Lennox-Gastaut-syndrome have generally a poor prognosis concerning the intellectual development. Not only clinically manifest seizures but also subclinical discharges could disturb the psychic condition of epileptic patients. Epileptic seizures are probably a reason for neuronal damage in the hippocampus area. Psychogenic reactions and undesired effects of antiepileptic drugs have to be considered aside from functional disturbances due to epileptic seizures.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"145 5","pages":"4-7"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18711576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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