ACS Organic & Inorganic Au最新文献

{"title":"","authors":"Olaf Tjabben, Tatiana Besset* and Olga García Mancheño*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsorginorgau.5c00034","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Squire J. Booker, Stephanie L. Brock, Xiangdong Li, Géraldine Masson, Sébastien Perrier, Vivek V. Ranade, Raymond E. Schaak, Gemma C. Solomon and Shelley D. Minteer*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsorginorgau.5c00062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Marcelo H. R. Carvalho, Pedro P. De Castro*, Pedro Beck, Hélio F. Dos Santos, Fabricio Machado, José R. Correa, Brenno A. D. Neto* and Giovanni W. Amarante*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsorginorgau.5c00049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Tatsuhiro Uchikura, Yuki Kaneko, Takanobu Setogawa, Tatsushi Oishi and Takahiko Akiyama*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsorginorgau.5c00039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Pravien S. Rajaram, Keerthana Chakkanalil, Jordan Galloway and Ryan D. Baxter*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsorginorgau.5c00026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Maxime Colpaert,  and , Bruno Ameduri*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsorginorgau.5c00030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Tomasz Wdowik, Egor Fedorov, Tina-Thien Ho, Patrick Duriez, Eugen Stulz* and Dorota Gryko*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":3.3,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/acsorginorgau.5c00025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding the PCET Thermochemistry of Cp^N3: N-H Bond Strengths of Metal-Free Cp^N3 Molecules and the Influence of Fe(CO)₃ Coordination.","authors":"David S Tresp, Tim K Schramm, Sanju Luhach, Amado Rosendo, Allison Houn, Tianyi Zhang, Amy Turtz, Jenny V Lockard, Andreas Hansen, Demyan E Prokopchuk","doi":"10.1021/acsorginorgau.5c00060","DOIUrl":"10.1021/acsorginorgau.5c00060","url":null,"abstract":"<p><p>Amine rich cyclopentadienyl (Cp^N3) ligands are electronically distinct from classical Cp ligand architectures, as they exhibit fascinating proton-coupled electron transfer (PCET) chemistry under acidic conditions in the presence and absence of transition metals. We now report that the exocyclic N-H bond of the isopropylamine moiety in [^RCp^N3]⁺ can be deprotonated under basic conditions (R = ⁱPr, ^<i>t</i> Bu), enabling the experimental determination of N-H bond strengths via p<i>K</i> _a and redox potential measurements in acetonitrile. From these data, the experimentally determined N-H acidity and bond dissociation free energy of [^iPrCp^N3]⁺ are p<i>K</i> _a = 22.6 and BDFE = 82.6 kcal/mol in acetonitrile. These results are linked with the known C-H bond thermochemistry data of [^iPrCp^N3]⁺, and computational (DFT) data sets are in excellent agreement with experiment. The exocyclic N-H bond acidity was also investigated with [^iPrCp^N3]⁺ coordinated to Fe-(CO)₃, and surprisingly, its p<i>K</i> _a is largely unperturbed in the presence of a transition metal (p<i>K</i> _a = 20-24 (experiment); 23.7 (DFT)). This prompted us to investigate the formal oxidation state of the iron center in our \"Fe^II\" starting material, with ⁵⁷Fe Mössbauer spectroscopy, XANES spectroscopy, charge distribution via reporter (CDVR) analysis, and computations, revealing that the metal center is best interpreted as having a +2 formal oxidation state. These data suggest that the electronic perturbations at the electron-rich Cp^N3 ligand upon coordination to Fe^II do not significantly influence the exocyclic N-H bond acidity.</p>","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 5","pages":"373-384"},"PeriodicalIF":3.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12492044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Synthesis of Biocompatible Gold Nanoparticles Using <i>Andrographis paniculata</i> Leaves Extract for Targeted Detection of Human Epidermal Growth Factor Receptor 2‑Positive Breast Cancer Cells.","authors":"Chirapond Chonanant, Pornsuda Maraming, Jureerut Daduang, Temduang Limpaiboon, Preeda Prakrankamanant, Nipaporn Ngernyuang","doi":"10.1021/acsorginorgau.5c00013","DOIUrl":"10.1021/acsorginorgau.5c00013","url":null,"abstract":"<p><p>Globally, breast cancer is the second leading cause of cancer-related mortality among women. Early detection, accurate diagnosis, and timely treatment are critical for improving survival rates. Therefore, developing a rapid and highly sensitive diagnostic method for early-stage breast cancer detection is essential. Human epidermal growth factor receptor 2 (HER2) is a well-characterized indicator of aggressiveness and poor prognosis in various cancers, including breast cancer. HER2-positive breast cancer represents about 15-20% of all cases, highlighting the significance of HER2 as both a prognostic and predictive biomarker. Gold nanoparticles (AuNPs) have emerged as promising tools in cancer diagnostics due to their unique optical and physicochemical properties. Among these, green-synthesized AuNPs are particularly attractive for biomedical applications due to their eco-friendliness and biocompatibility. <i>Andrographis paniculata</i> is a medicinal herb traditionally employed in the treatment of several diseases. Its leaf extract (ALE) contains various bioactive compounds, including flavonoids and diterpenoids, known for their strong reducing capabilities suitable for AuNP synthesis. In this study, we synthesized AuNPs using ALE (ALE-AuNPs) through a green, one-pot method. The ALE-AuNPs ranged from 11.12 ± 2.10 to 43.53 ± 10.53 nm in size, with a zeta potential of -21.00 ± 0.89 to -44.60 ± 2.36 mV. Cytotoxicity testing on MCF-7 cells indicated good biocompatibility. For targeted detection, the ALE-AuNPs were further functionalized with polyethylene glycol (PEG) and anti-HER2 antibodies, forming ALE-AuNPs+PEG+anti HER2. This nanoconjugate successfully detected HER2-positive MCF-7 cells via a 3,3',5,5'-tetramethylbenzidine-based colorimetric assay. To the best of our knowledge, this is the first report of a simple green synthesis of AuNPs from ALE for use as a colorimetric probe in HER2-positive breast cancer detection.</p>","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 5","pages":"328-337"},"PeriodicalIF":3.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12492039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and Characterization of the μ₆‑F Compounds [NEt₄][F(Cl₂)₃] and [NEt₄][F(Br₂)₃].","authors":"Jonas R Schmid, Patrick Pröhm, Patrick Voßnacker, Günther Thiele, Carsten Müller, Sebastian Riedel","doi":"10.1021/acsorginorgau.5c00064","DOIUrl":"10.1021/acsorginorgau.5c00064","url":null,"abstract":"<p><p>The reaction of tetraethylammonium polychlorides or polybromides in propionitrile with substoichiometric amounts of diluted fluorine at low temperatures leads to the non-classical interhalogen compounds [NEt₄]-[F-(X₂)₃] (X = Cl and Br). These compounds are the first examples of anions containing a central μ₆ fluoride anion, which is octahedrally surrounded by Br₂ or Cl₂ units, respectively. Single-crystal X-ray diffraction revealed that these compounds crystallize in the cubic system with every fluoride anion bridged by halogen units, resulting in a 3D network. Furthermore, single-crystal Raman and IR spectra were measured, and investigations using solid-state calculations were carried out.</p>","PeriodicalId":29797,"journal":{"name":"ACS Organic & Inorganic Au","volume":"5 5","pages":"400-405"},"PeriodicalIF":3.3,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12492038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}