Eldon Carlos Q. Gomes, Vívian N. Gonçalves, Marliete C. da Costa, Gustavo José C. d. Freitas, Daniel A. Santos, Susana Johann, Jefferson Bruno S. Oliveira, Tatiane A. d. Paixão, Peter Convey and Luiz H. Rosa*,
{"title":"","authors":"Eldon Carlos Q. Gomes, Vívian N. Gonçalves, Marliete C. da Costa, Gustavo José C. d. Freitas, Daniel A. Santos, Susana Johann, Jefferson Bruno S. Oliveira, Tatiane A. d. Paixão, Peter Convey and Luiz H. Rosa*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 4","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144344714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chuxin Yao, Jiao Tang, Guangcai Zhong*, Huimin Ma, Yangzhi Mo, Xiaofei Geng, Xin Yi, Qianyu Zhang, Jun Li, Shizhen Zhao and Gan Zhang*,
{"title":"The Intrinsic Link between Optical Properties and Toxicity of Extractable Organic Matter in Combustion Particles: Mediated by Polycyclic Aromatic Compounds","authors":"Chuxin Yao, Jiao Tang, Guangcai Zhong*, Huimin Ma, Yangzhi Mo, Xiaofei Geng, Xin Yi, Qianyu Zhang, Jun Li, Shizhen Zhao and Gan Zhang*, ","doi":"10.1021/envhealth.4c00267","DOIUrl":"10.1021/envhealth.4c00267","url":null,"abstract":"<p >Organic compounds are important contributors to the optical properties and health effects of combustion-derived particles. However, the connection between optical properties and toxicity of combustion particles remains a matter of little concern. In this study, combustion particles were collected from 11 primary sources, including biomass burning, coal combustion, and vehicle exhaust. The extractable organic matter (EOM) in bituminous coal combustion particles shows the highest light-absorption, fluorescence properties, and toxicity among samples. Parallel factor (PARAFAC) analysis combined excitation–emission matrix (EEM) spectroscopy resolved 4 types of basic chromophore components in EOM. Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) analysis further resolved ∼800 molecules, predominantly aromatics (84% ± 4.6%), which showed positive correlations with the light-absorption, fluorescence properties and toxicity of EOM (<i>p</i> < 0.05). Aromatics are inferred to be the intrinsic link between the optical properties and toxicity of EOM in combustion particles. Additionally, the benzene poly(carboxylic acid)s (BPCAs) method, which could identify and quantify fused benzene rings in EOM, further indicates the high condensation degree of aromatics is closely correlated with the light-absorption, fluorescence properties of EOM. However, the toxicity of EOM may depend on the bay or fjord region of aromatics. These findings provide valuable insights into the light-absorption, fluorescence properties and toxicity of EOM in combustion particles.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 7","pages":"768–776"},"PeriodicalIF":6.3,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281203/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David A. Holcomb, Jackie Knee, Zaida Adriano, Drew Capone, Oliver Cumming, Erin Kowalsky, Rassul Nalá, Edna Viegas, Jill R. Stewart and Joe Brown*,
{"title":"Associations between Fecal Contamination of the Household Environment and Enteric Pathogen Detection in Children Living in Maputo, Mozambique","authors":"David A. Holcomb, Jackie Knee, Zaida Adriano, Drew Capone, Oliver Cumming, Erin Kowalsky, Rassul Nalá, Edna Viegas, Jill R. Stewart and Joe Brown*, ","doi":"10.1021/envhealth.4c00283","DOIUrl":"10.1021/envhealth.4c00283","url":null,"abstract":"<p >Environmental exposure to enteric pathogens is generally assessed using fecal indicators but relationships between markers of fecal contamination and actual exposure to enteric pathogens remain poorly characterized. We investigated whether <i>Escherichia coli</i> and two human fecal markers (HF183 and Mnif) in urban Mozambican household soil and drinking water were associated with detection of eight bacteria, three viruses, and three protozoa measured by multiplex reverse-transcription PCR and soil transmitted helminths assessed by microscopy in stool samples from children. We used mixed-effects logistic regression with marginal standardization to obtain a pooled estimate of the overall indicator-pathogen relationship while simultaneously estimating pathogen-specific associations that accounted for assessing multiple pathogens per sample. At least one pathogen was detected in 88% (169/192) of stool samples from children. Increasing drinking water <i>E. coli</i> gene concentration was associated with higher <i>Ascaris</i> prevalence, while human HF183 in drinking water was weakly associated with lower prevalence of the most common pathogens but was infrequently detected. No fecal marker in the soil was clearly associated with any pathogen. We did not find evidence to support human markers as reliable indicators of enteric pathogen carriage in a high-prevalence domestic setting and recommend targeting enteric pathogens directly.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 7","pages":"757–767"},"PeriodicalIF":6.3,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281200/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
