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Environment & Health Pub Date : 2025-03-21
Yushi Jin, Boyuan Xue and Xiaohong Zhou*, 
{"title":"","authors":"Yushi Jin, Boyuan Xue and Xiaohong Zhou*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 3","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00160","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144438443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Environment & Health Pub Date : 2025-03-21
Lucca Caiaffa Santos Rosa, Mariam Sarhan and Andre Silva Pimentel*, 
{"title":"","authors":"Lucca Caiaffa Santos Rosa, Mariam Sarhan and Andre Silva Pimentel*, ","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 3","pages":"XXX-XXX XXX-XXX"},"PeriodicalIF":0.0,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/pdf/10.1021/envhealth.4c00218","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144438444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioaccumulation and Maternal Transfer of Brominated Flame Retardants in Poultry and the Health Risks from Dietary Exposure. 溴化阻燃剂在家禽体内的生物积累和母体转移以及饮食暴露的健康风险。
Environment & Health Pub Date : 2025-03-17 eCollection Date: 2025-07-18 DOI: 10.1021/envhealth.4c00260
Ying Li, Ling Wang, Lei Shi, Yinghua Lou, Aifeng Liu, Yongfeng Lin, Ruixia Yang, Wei Gao, Guangbo Qu
{"title":"Bioaccumulation and Maternal Transfer of Brominated Flame Retardants in Poultry and the Health Risks from Dietary Exposure.","authors":"Ying Li, Ling Wang, Lei Shi, Yinghua Lou, Aifeng Liu, Yongfeng Lin, Ruixia Yang, Wei Gao, Guangbo Qu","doi":"10.1021/envhealth.4c00260","DOIUrl":"10.1021/envhealth.4c00260","url":null,"abstract":"<p><p>The limitation of legacy hexabromocyclododecanes (HBCDs) and increasing usage of emerging brominated flame retardant (BFR) tetrabromobisphenol A (TBBPA) resulted in their co-exposure to organisms. In this study, domestic chicken and environmental samples collected near a BFR manufacturing zone were analyzed to determine the bioaccumulation and transfer of HBCDs and TBBPA. The mean concentrations of ∑<sub>3</sub>HBCDs, TBBPA, ∑<sub>4</sub>TBBPA-related derivatives, ∑<sub>9</sub>TBBPA-related byproducts, and ∑<sub>16</sub>TBBPA-related transformation products in chicken tissues were 1207, 0.20, 15087, 0.96, and 6384 ng/g lipid weight, respectively. Exposure to sources of BFR contamination (soil, feed, and water) could be the main cause of high BFR levels in chickens. α-HBCD and bis-substituted TBBPA analogues have higher bioaccumulation factor levels than TBBPA and other compounds, indicating greater bioconcentration potential for substances with higher log<i>K</i> <sub>ow</sub>. HBCDs, TBBPA, and TBBPA analogues tend to be enriched in the chicken comb and spleen and can cross the blood-brain barrier into the brain. However, while these compounds accumulate in the mother, they are also subject to metabolic processes that lead to their eventual excretion. Low-persistence BFRs were more favorable to maternal transfer, while compounds with high persistence tended to be retained in the mother. Although dietary intake of BFRs through chicken consumption poses a low risk to the general population, concerns remain regarding the synergistic risk of BFRs.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 7","pages":"723-732"},"PeriodicalIF":0.0,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sorption, Extraction, and Characterization of Polycyclic Aromatic Hydrocarbons in Environmentally Weathered Microplastics, Particulate Organic Matter, Sediment, and Fish Species in the Lavaca-Matagorda Bay System. Lavaca-Matagorda湾系统中环境风化微塑料、颗粒有机物质、沉积物和鱼类对多环芳烃的吸附、提取和表征
Environment & Health Pub Date : 2025-03-14 eCollection Date: 2025-06-20 DOI: 10.1021/envhealth.4c00223
Oluniyi O Fadare, Nigel Lascelles, Jessica Myers, Andrew Gray, Jeremy L Conkle
{"title":"Sorption, Extraction, and Characterization of Polycyclic Aromatic Hydrocarbons in Environmentally Weathered Microplastics, Particulate Organic Matter, Sediment, and Fish Species in the Lavaca-Matagorda Bay System.","authors":"Oluniyi O Fadare, Nigel Lascelles, Jessica Myers, Andrew Gray, Jeremy L Conkle","doi":"10.1021/envhealth.4c00223","DOIUrl":"10.1021/envhealth.4c00223","url":null,"abstract":"<p><p>The historical industrial input of polycyclic aromatic hydrocarbons (PAHs) and, more recently, microplastics into the Lavaca-Matagorda Bay system is a threat to its health and the region's fishery economy. Our study assessed the role of microplastics in PAH mobility within Lavaca-Matagorda Bay. We investigated concentrations of the EPA's 16 high-priority PAHs on microplastics, particulate organic matter, and surface sediments. Additionally, the gastrointestinal tracts of three economically important fishes within the bay [<i>Paralichthys lethostigma</i> (<i>n</i> = 46), <i>Sciaenops ocellatus</i> (<i>n</i> = 47), and <i>Cynoscion nebulosus</i> (<i>n</i> = 85)] were examined for microplastics, while their liver and muscle tissue were analyzed for PAHs. In all three matrices, the average concentration of ∑16PAHs ranged from 890.2 to 28,574.0 ng·g<sup>-1</sup>. The average individual PAH concentration in fish species ranged from 75.1 to 145.4 ng·g<sup>-1</sup>. Fish species in all of the sampling sites were classified between minimally and moderately polluted, with potential PAH bioaccumulation observed only in the southern flounder. About 67% of all of the analyzed sediment samples from Lavaca-Matagorda Bay indicate possible adverse or moderate adverse biological effects. This demonstrates the need for greater remediation of the existing pollution and continued monitoring of industrial discharges within Lavaca-Matagorda Bay to reduce harm to the ecosystem and the local economy.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 6","pages":"690-700"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sorption, Extraction, and Characterization of Polycyclic Aromatic Hydrocarbons in Environmentally Weathered Microplastics, Particulate Organic Matter, Sediment, and Fish Species in the Lavaca-Matagorda Bay System Lavaca-Matagorda湾系统中环境风化微塑料、颗粒有机物质、沉积物和鱼类对多环芳烃的吸附、提取和表征
Environment & Health Pub Date : 2025-03-14 DOI: 10.1021/envhealth.4c0022310.1021/envhealth.4c00223
Oluniyi O. Fadare*, Nigel Lascelles, Jessica Myers, Andrew Gray and Jeremy L. Conkle, 
{"title":"Sorption, Extraction, and Characterization of Polycyclic Aromatic Hydrocarbons in Environmentally Weathered Microplastics, Particulate Organic Matter, Sediment, and Fish Species in the Lavaca-Matagorda Bay System","authors":"Oluniyi O. Fadare*,&nbsp;Nigel Lascelles,&nbsp;Jessica Myers,&nbsp;Andrew Gray and Jeremy L. Conkle,&nbsp;","doi":"10.1021/envhealth.4c0022310.1021/envhealth.4c00223","DOIUrl":"https://doi.org/10.1021/envhealth.4c00223https://doi.org/10.1021/envhealth.4c00223","url":null,"abstract":"<p >The historical industrial input of polycyclic aromatic hydrocarbons (PAHs) and, more recently, microplastics into the Lavaca-Matagorda Bay system is a threat to its health and the region’s fishery economy. Our study assessed the role of microplastics in PAH mobility within Lavaca-Matagorda Bay. We investigated concentrations of the EPA’s 16 high-priority PAHs on microplastics, particulate organic matter, and surface sediments. Additionally, the gastrointestinal tracts of three economically important fishes within the bay [<i>Paralichthys lethostigma</i> (<i>n</i> = 46), <i>Sciaenops ocellatus</i> (<i>n</i> = 47), and <i>Cynoscion nebulosus</i> (<i>n</i> = 85)] were examined for microplastics, while their liver and muscle tissue were analyzed for PAHs. In all three matrices, the average concentration of ∑16PAHs ranged from 890.2 to 28,574.0 ng·g<sup>–1</sup>. The average individual PAH concentration in fish species ranged from 75.1 to 145.4 ng·g<sup>–1</sup>. Fish species in all of the sampling sites were classified between minimally and moderately polluted, with potential PAH bioaccumulation observed only in the southern flounder. About 67% of all of the analyzed sediment samples from Lavaca-Matagorda Bay indicate possible adverse or moderate adverse biological effects. This demonstrates the need for greater remediation of the existing pollution and continued monitoring of industrial discharges within Lavaca-Matagorda Bay to reduce harm to the ecosystem and the local economy.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 6","pages":"690–700 690–700"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/envhealth.4c00223","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144320720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimal Gestational Weight Gain and Fetal Growth in Urban Environments: The Role of Residential Greenness. 城市环境下最佳妊娠增重与胎儿生长:居住绿化的作用
Environment & Health Pub Date : 2025-03-14 eCollection Date: 2025-07-18 DOI: 10.1021/envhealth.4c00185
Si-Wei Zhang, Yanhui Hao, Jia-Xin Chen, Si-Yue Chen, Wen Yu, Jia-Ying Wu, Cheng Li, Xia Meng, Yan-Ting Wu
{"title":"Optimal Gestational Weight Gain and Fetal Growth in Urban Environments: The Role of Residential Greenness.","authors":"Si-Wei Zhang, Yanhui Hao, Jia-Xin Chen, Si-Yue Chen, Wen Yu, Jia-Ying Wu, Cheng Li, Xia Meng, Yan-Ting Wu","doi":"10.1021/envhealth.4c00185","DOIUrl":"10.1021/envhealth.4c00185","url":null,"abstract":"<p><p>The influence of residential greenness on maternal gestational weight gain (GWG) and fetal intrauterine growth remains understudied. This study examined the impact of residential greenness on GWG and fetal intrauterine growth and assessed the mediating role of GWG. The research included 29406 births in Shanghai, utilizing the normalized difference vegetation index (NDVI) to measure greenness within a 500 m radius (NDVI-500). The analysis employed a generalized linear model to assess the impacts of residental greenness on GWG, fetal growth and birthweight, and a mediation analysis to explore GWG's role between greenness and fetal development. Results indicated that significant benefits were observed with increased greenness, where each 0.1 unit increase in NDVI-500 was associated with reductions of 9.4% (95% CI: 5.5%-13.2%) in the risk of head circumference undergrowth and 8.5% (95% CI: 4.8%-12.2%) in estimated fetal weight undergrowth. Additionally, each 0.1 unit increase in NDVI-500 was associated with reductions of 9.4% (95% CI: 5.1%-13.5%) and 9.2% (95% CI: 6.2%-12.0%) in the risk of inadequate and excessive GWG, respectively. Notably, total GWG mediated 17.5% of the relationship between NDVI-500 and the birth weight. These findings suggest that enhancing residential greenness could be an effective public health strategy to improve pregnancy outcomes by promoting fetal growth and managing GWG, with the GWG partially mediating these benefits.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 7","pages":"714-722"},"PeriodicalIF":0.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12281196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychiatric Disorders Mediate the Association between Floods and Dementia: A Prospective Cohort Study in the UK Biobank 精神疾病介导洪水和痴呆之间的关系:英国生物银行的一项前瞻性队列研究
Environment & Health Pub Date : 2025-03-13 DOI: 10.1021/envhealth.4c0024110.1021/envhealth.4c00241
Yao Wu, Bo Wen, Danijela Gasevic, Rongbin Xu, Zhengyu Yang, Pei Yu, Yanming Liu, Guowei Zhou, Yan Zhang, Jiangning Song, Hong Liu, Shanshan Li and Yuming Guo*, 
{"title":"Psychiatric Disorders Mediate the Association between Floods and Dementia: A Prospective Cohort Study in the UK Biobank","authors":"Yao Wu,&nbsp;Bo Wen,&nbsp;Danijela Gasevic,&nbsp;Rongbin Xu,&nbsp;Zhengyu Yang,&nbsp;Pei Yu,&nbsp;Yanming Liu,&nbsp;Guowei Zhou,&nbsp;Yan Zhang,&nbsp;Jiangning Song,&nbsp;Hong Liu,&nbsp;Shanshan Li and Yuming Guo*,&nbsp;","doi":"10.1021/envhealth.4c0024110.1021/envhealth.4c00241","DOIUrl":"https://doi.org/10.1021/envhealth.4c00241https://doi.org/10.1021/envhealth.4c00241","url":null,"abstract":"<p >Flooding has become more frequent and severe worldwide, leading to an increased burden of psychiatric disorders (e.g., depression and anxiety). Psychiatric disorders are associated with an increased risk of subsequent dementia. However, the associations among floods, psychiatric disorders, and dementia are still unclear. Using a population cohort from the UK Biobank, we aimed to investigate the mediating role of psychiatric disorders on the associations between floods and dementia. In this study, cumulative exposure to floods over an eight-year period preceding the study baseline was assessed for each participant at residential addresses. Multivariable Cox proportional hazards regression was used to study the associations of flooding exposure with psychiatric disorders and dementia. Stratified analyses and mediation analyses were conducted to examine whether psychiatric disorders mediate the relationship between floods and dementia. During a median follow-up of 12.3 years (interquartile range: 11.6–13.0), 0.9% (2,028) of participants developed dementia and 9.5% (21,629) were diagnosed with psychiatric disorders. The flooding exposure was associated with an 8.0% increased risk of incident dementia (Hazard Ratio [HR]: 1.080, 95% CI: 1.023–1.141). The flood–dementia association was observed to be partially mediated by several subtypes of psychiatric disorders (overall proportion of mediation: 75.7%), with psychotic disorder accounting for 49.7% (indirect effect HR: 1.039, 95% confidence interval: 1.015–1.064) of flood-related dementia, followed by stress-related disorder (proportion of mediation: 18.1%), and depression (proportion of mediation: 3.9%). This study provides evidence of an increased risk of dementia associated with exposure to floods, with psychiatric disorders playing a crucial mediating role in the flood-related dementia pathway. These findings suggest that flooding exposure is a critical risk factor for dementia, and targeted interventions addressing postdisaster mental health may be crucial for dementia prevention in affected populations.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 6","pages":"680–689 680–689"},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/envhealth.4c00241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144320719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychiatric Disorders Mediate the Association between Floods and Dementia: A Prospective Cohort Study in the UK Biobank. 精神疾病介导洪水和痴呆之间的关系:英国生物银行的一项前瞻性队列研究。
Environment & Health Pub Date : 2025-03-13 eCollection Date: 2025-06-20 DOI: 10.1021/envhealth.4c00241
Yao Wu, Bo Wen, Danijela Gasevic, Rongbin Xu, Zhengyu Yang, Pei Yu, Yanming Liu, Guowei Zhou, Yan Zhang, Jiangning Song, Hong Liu, Shanshan Li, Yuming Guo
{"title":"Psychiatric Disorders Mediate the Association between Floods and Dementia: A Prospective Cohort Study in the UK Biobank.","authors":"Yao Wu, Bo Wen, Danijela Gasevic, Rongbin Xu, Zhengyu Yang, Pei Yu, Yanming Liu, Guowei Zhou, Yan Zhang, Jiangning Song, Hong Liu, Shanshan Li, Yuming Guo","doi":"10.1021/envhealth.4c00241","DOIUrl":"10.1021/envhealth.4c00241","url":null,"abstract":"<p><p>Flooding has become more frequent and severe worldwide, leading to an increased burden of psychiatric disorders (e.g., depression and anxiety). Psychiatric disorders are associated with an increased risk of subsequent dementia. However, the associations among floods, psychiatric disorders, and dementia are still unclear. Using a population cohort from the UK Biobank, we aimed to investigate the mediating role of psychiatric disorders on the associations between floods and dementia. In this study, cumulative exposure to floods over an eight-year period preceding the study baseline was assessed for each participant at residential addresses. Multivariable Cox proportional hazards regression was used to study the associations of flooding exposure with psychiatric disorders and dementia. Stratified analyses and mediation analyses were conducted to examine whether psychiatric disorders mediate the relationship between floods and dementia. During a median follow-up of 12.3 years (interquartile range: 11.6-13.0), 0.9% (2,028) of participants developed dementia and 9.5% (21,629) were diagnosed with psychiatric disorders. The flooding exposure was associated with an 8.0% increased risk of incident dementia (Hazard Ratio [HR]: 1.080, 95% CI: 1.023-1.141). The flood-dementia association was observed to be partially mediated by several subtypes of psychiatric disorders (overall proportion of mediation: 75.7%), with psychotic disorder accounting for 49.7% (indirect effect HR: 1.039, 95% confidence interval: 1.015-1.064) of flood-related dementia, followed by stress-related disorder (proportion of mediation: 18.1%), and depression (proportion of mediation: 3.9%). This study provides evidence of an increased risk of dementia associated with exposure to floods, with psychiatric disorders playing a crucial mediating role in the flood-related dementia pathway. These findings suggest that flooding exposure is a critical risk factor for dementia, and targeted interventions addressing postdisaster mental health may be crucial for dementia prevention in affected populations.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 6","pages":"680-689"},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unseen Threats: The Impact of Relatively Low-Level Ambient Air Pollution on Autoimmune Diseases. 看不见的威胁:相对低水平的环境空气污染对自身免疫性疾病的影响。
Environment & Health Pub Date : 2025-03-12 eCollection Date: 2025-06-20 DOI: 10.1021/envhealth.4c00281
Rui-Xue Leng, Wenbiao Hu
{"title":"Unseen Threats: The Impact of Relatively Low-Level Ambient Air Pollution on Autoimmune Diseases.","authors":"Rui-Xue Leng, Wenbiao Hu","doi":"10.1021/envhealth.4c00281","DOIUrl":"10.1021/envhealth.4c00281","url":null,"abstract":"<p><p>In developing countries like China, personal air-purifying respirators and indoor air purifiers are commonly used to mitigate high levels of air pollution, whereas lower pollution levels in many developed countries lead to less proactive measures. However, emerging evidence suggests that even relatively low-level air pollution can elevate the risk of autoimmune diseases. Recent biobank studies demonstrated a linear relationship between chronic exposure to relatively low-level ambient air pollution and the incidence of autoimmune diseases, particularly in genetically susceptible populations. Furthermore, evidence indicates that short-term exposure to low levels of PM<sub>2.5</sub> is associated with disease flares. This Viewpoint highlights the often-overlooked risks of low-level air pollution in contributing to autoimmune diseases in individuals with genetic predispositions; it aims to raise awareness of prevention strategies and advocate nonpharmacological interventions at both the population and individual levels, to protect high-risk groups and alleviate the burden of autoimmune diseases.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 6","pages":"571-574"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186204/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144498222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unseen Threats: The Impact of Relatively Low-Level Ambient Air Pollution on Autoimmune Diseases 看不见的威胁:相对低水平的环境空气污染对自身免疫性疾病的影响
Environment & Health Pub Date : 2025-03-12 DOI: 10.1021/envhealth.4c0028110.1021/envhealth.4c00281
Rui-Xue Leng*,  and , Wenbiao Hu*, 
{"title":"Unseen Threats: The Impact of Relatively Low-Level Ambient Air Pollution on Autoimmune Diseases","authors":"Rui-Xue Leng*,&nbsp; and ,&nbsp;Wenbiao Hu*,&nbsp;","doi":"10.1021/envhealth.4c0028110.1021/envhealth.4c00281","DOIUrl":"https://doi.org/10.1021/envhealth.4c00281https://doi.org/10.1021/envhealth.4c00281","url":null,"abstract":"<p >In developing countries like China, personal air-purifying respirators and indoor air purifiers are commonly used to mitigate high levels of air pollution, whereas lower pollution levels in many developed countries lead to less proactive measures. However, emerging evidence suggests that even relatively low-level air pollution can elevate the risk of autoimmune diseases. Recent biobank studies demonstrated a linear relationship between chronic exposure to relatively low-level ambient air pollution and the incidence of autoimmune diseases, particularly in genetically susceptible populations. Furthermore, evidence indicates that short-term exposure to low levels of PM<sub>2.5</sub> is associated with disease flares. This Viewpoint highlights the often-overlooked risks of low-level air pollution in contributing to autoimmune diseases in individuals with genetic predispositions; it aims to raise awareness of prevention strategies and advocate nonpharmacological interventions at both the population and individual levels, to protect high-risk groups and alleviate the burden of autoimmune diseases.</p>","PeriodicalId":29795,"journal":{"name":"Environment & Health","volume":"3 6","pages":"571–574 571–574"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.acs.org/doi/epdf/10.1021/envhealth.4c00281","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144320718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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