Urologie最新文献_第6页

[Update guideline on prostate cancer-balancing act between evidence and healthcare reality]. [更新前列腺癌指南-在证据和医疗现实之间的平衡行为]。

IF 0.4 4区医学

Urologie Pub Date : 2025-09-01 Epub Date: 2025-08-20 DOI: 10.1007/s00120-025-02662-x

Axel Belusa, Peter J Goebell, Peter Kollenbach, Mira Faßbach, Peter Kühne, Sulafah El-Khadra, Thomas Quack, Mario Kramer

引用次数: 0

Termine. Termine。

IF 0.4 4区医学

Urologie Pub Date : 2025-09-01 DOI: 10.1007/s00120-025-02671-w

引用次数: 0

[Digital health: a green future for healthcare?] 数字健康：医疗保健的绿色未来？］

IF 0.4 4区医学

Urologie Pub Date : 2025-09-01 Epub Date: 2025-07-21 DOI: 10.1007/s00120-025-02637-y

Stephan O Adler, Daniela Hery, Eduard C Groen, Jean Stadlbauer, Theresa D Ahrens

{"title":"[Digital health: a green future for healthcare?]","authors":"Stephan O Adler, Daniela Hery, Eduard C Groen, Jean Stadlbauer, Theresa D Ahrens","doi":"10.1007/s00120-025-02637-y","DOIUrl":"10.1007/s00120-025-02637-y","url":null,"abstract":"The healthcare sector is doubly affected by the climate crisis. On the one hand, the number of disease and injury cases will increase due to various effects such as heatwaves or natural disasters, further burdening the healthcare system. On the other hand, the healthcare sector itself significantly contributes to the emissions that exacerbate the climate crisis. A seemingly unsolvable vicious circle. That is why the present article discusses the relationship between digital health and sustainability in healthcare. Digital innovations such as telemedicine, digital diagnostics, or the use of artificial intelligence can increase efficiency and thus significantly relieve the burden on medical professionals. For the advantages of these technologies to outweigh inherent disadvantages like their high energy demand, digital and sustainable transformations must be addressed simultaneously. This so-called \"twin transformation\" shows that it can even unleash synergies. Therefore, this article describes interesting technological approaches and current research topics such as digital twins of patients and their sustainable design for healthcare. In addition, examples specific to urology are presented.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"892-899"},"PeriodicalIF":0.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144675977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Atypical contrast enhancement in mucinous prostate cancer : Limitations of the PI-RADS (Prostate Imaging Reporting and Data System) classification and implications for modern imaging]. [非典型前列腺黏液癌造影剂增强：PI-RADS（前列腺成像报告和数据系统）分类的局限性及其对现代影像学的影响]。

IF 0.4 4区医学

Urologie Pub Date : 2025-08-21 DOI: 10.1007/s00120-025-02663-w

Julio Ruben Rodas Garzaro, Anton Kravchuk, Johannes Moersler, Stephan Siepmann, Elisabeth Stemplinger, Fabian Eder, Matthias May, Christian Gilfrich

引用次数: 0

[Gender-specific differences in outcome and survival in early cystectomy : Systematic review]. [早期膀胱切除术的结果和生存的性别差异：系统回顾]。

IF 0.4 4区医学

Urologie Pub Date : 2025-08-05 DOI: 10.1007/s00120-025-02665-8

Laila Schneidewind, Bernhard Kiss, Nicolas Arnold, Jennifer Kranz, Friedemann Zengerling, Annabel Spek, Thomas Neumann, Annemarie Uhlig

{"title":"[Gender-specific differences in outcome and survival in early cystectomy : Systematic review].","authors":"Laila Schneidewind, Bernhard Kiss, Nicolas Arnold, Jennifer Kranz, Friedemann Zengerling, Annabel Spek, Thomas Neumann, Annemarie Uhlig","doi":"10.1007/s00120-025-02665-8","DOIUrl":"https://doi.org/10.1007/s00120-025-02665-8","url":null,"abstract":"Background: Despite a lower incidence, women with bladder cancer have poorer survival rates than men. However, studies to date have provided insufficient data on gender-specific treatment outcomes, particularly after radical early cystectomy for Bacillus Calmette-Guérin (BCG) failure.Objectives: Are there gender-specific differences in oncologic outcomes and complication rates after radical early cystectomy in patients with nonmuscle invasive bladder cancer after failure of BCG instillation therapy?Materials and methods: A systematic literature search was conducted in MEDLINE and the Cochrane Library in January 2025. The complete study protocol has been prospectively registered at PROSPERO (ID CRD42024611111).Results: Three retrospective cohort studies with a total of 655 patients (18.8% of whom were women) were included. There were no significant gender-specific differences in terms of overall survival, cancer-specific survival, or progression. Data on complications and quality of life were limited or not available. In two studies, prostatic urethral involvement was identified as a negative prognostic marker in men.Conclusion: The current evidence base is sparse, methodologically limited, and biased by the underrepresentation of women. Therefore, it is not possible to make reliable statements on the effect of gender on the efficacy of early cystectomy after BCG failure. Further research on gender-dependent risk factors, especially hormonal and immunological influences, is urgently needed to develop personalized treatment strategies.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144790142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Patient management in emergency and acute care: well-considered decision-making instead of actionism]. [急诊和急症护理中的病人管理：深思熟虑的决策而不是行动主义]。

IF 0.5 4区医学

Urologie Pub Date : 2025-08-01 Epub Date: 2025-06-26 DOI: 10.1007/s00120-025-02607-4

Christian Pfeiffer

引用次数: 0

[PSA in the extreme range-an expression of an unfavorable prognosis? : A review of course and treatment of prostate cancer with prostate-specific antigen (PSA) values in the three-to-four-digit range]. PSA在极端范围-预后不良的表现？前列腺特异性抗原（PSA）值在3 - 4位数范围内的前列腺癌的病程和治疗综述。

IF 0.5 4区医学

Urologie Pub Date : 2025-08-01 Epub Date: 2025-05-19 DOI: 10.1007/s00120-025-02583-9

Christian Dirscherl, Thomas Ebert, Bernd J Schmitz-Dräger, Peter J Goebell

{"title":"[PSA in the extreme range-an expression of an unfavorable prognosis? : A review of course and treatment of prostate cancer with prostate-specific antigen (PSA) values in the three-to-four-digit range].","authors":"Christian Dirscherl, Thomas Ebert, Bernd J Schmitz-Dräger, Peter J Goebell","doi":"10.1007/s00120-025-02583-9","DOIUrl":"10.1007/s00120-025-02583-9","url":null,"abstract":"Background: Extremely high baseline prostate-specific antigen (bPSA) values in the range of 100 to ≥ 1000 ng/ml prior to the start of systemic therapy pose a challenge, as they can lead to the impression of a very unfavorable prognosis.Objective: We investigated factors influencing 5‑year overall survival (5-yOS) and the treatment modalities of patients with bPSA levels ≥ 100 ng/ml using retrospective data.Materials and methods: We defined items from a limited initial collective, which we then used for a query in the UroCloud database. A total of 695 patients were included.Results and conclusion: For the entire collective, the 5‑yOS was 68.5% ± 2.7%. The bPSA value had a significant (p < 0.001) influence on 5‑yOS in the following groups: 100-149 ng/ml, 150-249 ng/ml, 250-649 ng/ml, and ≥ 650 ng/ml (5-yOS: 77.0% ± 4.9% vs. 76.9% ± 4.5% vs. 61.4% ± 6.0 vs. 57.4% ± 6.1%, respectively). Age ≤ 70 years compared to > 70 years at first diagnosis resulted in a significant difference regarding 5‑yOS (74.8% ± 3.5% vs. 60.1% ± 4.4, respectively). A PSA response of > 90%, which was achieved in 79.0% of cases, had a significant influence on 5‑yOS compared to a response of ≤ 90% (73.5% ± 2.9% vs. 48.6% ± 6.7%, respectively). There was also a significant 5‑yOS advantage if a first PSA nadir of ≤ 0.20 ng/ml was achieved (in 22.2%) compared to a first PSA nadir of > 0.20 ng/ml (89.8% ± 3.3% vs. 60.4% ± 3.5%, respectively). In 49.4% (n = 343) of cases, androgen deprivation therapy (ADT) monotherapy was started as first-line systemic therapy. Between 1999 and 2023, we saw an increase in escalated and initial combination therapies. The analysis shows that an extreme bPSA value is not in itself an expression of an unfavorable prognosis.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"803-814"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12287150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144094246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Cooperation instead of competition-new approaches in urological care]. 以合作代替竞争——泌尿外科护理的新途径。

IF 0.5 4区医学

Urologie Pub Date : 2025-08-01 Epub Date: 2025-05-31 DOI: 10.1007/s00120-025-02615-4

Jens Westphal

{"title":"[Cooperation instead of competition-new approaches in urological care].","authors":"Jens Westphal","doi":"10.1007/s00120-025-02615-4","DOIUrl":"10.1007/s00120-025-02615-4","url":null,"abstract":"Urological care in Germany is in a state of flux. New interfaces are emerging between outpatient and inpatient structures, which pose not only organizational and professional but also economic challenges. The central challenge is the increasing importance of outpatient care and its integration into everyday clinical practice and the associated cooperation between hospitals and community-based physicians, including in the context of urological training. Only through close and trusting cooperation is it possible to ensure high-quality patient care and act in an economically sensible manner. The author is particularly critical of the \"cold\" streamlining of the hospital landscape in North Rhine-Westphalia due to the increasing insolvency of hospitals. This could also jeopardize urological care in the medium and long term. Existing urological hospital structures, especially inpatient departments, have been closed, while the care of urological patients has been made considerably more difficult due to a lack of opportunities for expansion, e.g., of operating room capacities in the hospitals providing care. At the same time, the article aims to provide encouragement. The younger generation in particular is prepared to think, act and work across sectors. The author appeals to all those involved to see cooperation not as a necessary evil, but as a strategic opportunity. This is the only way that patient care can be guaranteed in the future in a comprehensive and quality-assured manner. It is not just about medical expertise, but also about structure, communication and trust between the people involved.","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":"762-768"},"PeriodicalIF":0.5,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144192348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of primary RPLND in clinical stage IIA/B testicular germ cell tumor: a narrative review. 原发性RPLND在临床IIA/B期睾丸生殖细胞瘤中的作用：一个叙述性的回顾。

IF 0.4 4区医学

Urologie Pub Date : 2025-08-01 DOI: 10.1007/s00120-025-02648-9

Parth Thakker, Connor Drake, Timothy Masterson, Clint Cary

引用次数: 0

[Healthcare without boundaries: revolution in cross-sector healthcare delivery]. [无国界医疗：跨部门医疗服务的革命]。

IF 0.5 4区医学

Urologie Pub Date : 2025-08-01 Epub Date: 2025-06-24 DOI: 10.1007/s00120-025-02622-5

Severin Pöchtrager

引用次数: 0