Julio Ruben Rodas Garzaro, Anton Kravchuk, Johannes Moersler, Stephan Siepmann, Elisabeth Stemplinger, Fabian Eder, Matthias May, Christian Gilfrich
{"title":"[非典型前列腺黏液癌造影剂增强：PI-RADS（前列腺成像报告和数据系统）分类的局限性及其对现代影像学的影响]。","authors":"Julio Ruben Rodas Garzaro, Anton Kravchuk, Johannes Moersler, Stephan Siepmann, Elisabeth Stemplinger, Fabian Eder, Matthias May, Christian Gilfrich","doi":"10.1007/s00120-025-02663-w","DOIUrl":null,"url":null,"abstract":"<p><p>Mucinous prostate carcinoma (mucPCa) often evades detection by prostate-imaging reporting and data system (PI-RADS)-based multiparametric magnetic resonance imaging (MRI). We report a case in which atypical dynamic contrast kinetics served as the sole imaging clue leading to the diagnosis of aggressive mucPCa. Neither T2-weighted nor diffusion-weighted sequences suggested malignancy. Only a targeted MRI/ultrasonography (US) fusion biopsy confirmed an International Society of Urological Pathology (ISUP) grade 4 mucPCa. This case underscores the diagnostic limitations of standardized imaging protocols and highlights the critical importance of contrast enhancement in rare histological subtypes.</p>","PeriodicalId":29782,"journal":{"name":"Urologie","volume":" ","pages":""},"PeriodicalIF":0.4000,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Atypical contrast enhancement in mucinous prostate cancer : Limitations of the PI-RADS (Prostate Imaging Reporting and Data System) classification and implications for modern imaging].\",\"authors\":\"Julio Ruben Rodas Garzaro, Anton Kravchuk, Johannes Moersler, Stephan Siepmann, Elisabeth Stemplinger, Fabian Eder, Matthias May, Christian Gilfrich\",\"doi\":\"10.1007/s00120-025-02663-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Mucinous prostate carcinoma (mucPCa) often evades detection by prostate-imaging reporting and data system (PI-RADS)-based multiparametric magnetic resonance imaging (MRI). We report a case in which atypical dynamic contrast kinetics served as the sole imaging clue leading to the diagnosis of aggressive mucPCa. Neither T2-weighted nor diffusion-weighted sequences suggested malignancy. Only a targeted MRI/ultrasonography (US) fusion biopsy confirmed an International Society of Urological Pathology (ISUP) grade 4 mucPCa. This case underscores the diagnostic limitations of standardized imaging protocols and highlights the critical importance of contrast enhancement in rare histological subtypes.</p>\",\"PeriodicalId\":29782,\"journal\":{\"name\":\"Urologie\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2025-08-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Urologie\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s00120-025-02663-w\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Urologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00120-025-02663-w","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
[Atypical contrast enhancement in mucinous prostate cancer : Limitations of the PI-RADS (Prostate Imaging Reporting and Data System) classification and implications for modern imaging].
Mucinous prostate carcinoma (mucPCa) often evades detection by prostate-imaging reporting and data system (PI-RADS)-based multiparametric magnetic resonance imaging (MRI). We report a case in which atypical dynamic contrast kinetics served as the sole imaging clue leading to the diagnosis of aggressive mucPCa. Neither T2-weighted nor diffusion-weighted sequences suggested malignancy. Only a targeted MRI/ultrasonography (US) fusion biopsy confirmed an International Society of Urological Pathology (ISUP) grade 4 mucPCa. This case underscores the diagnostic limitations of standardized imaging protocols and highlights the critical importance of contrast enhancement in rare histological subtypes.
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