AME Case Reports最新文献

{"title":"Nursing management of a patient with central retinal artery occlusion after percutaneous coronary intervention: a case report.","authors":"Yan Zhang, Yingtong Meng, Tingting Zhang, Siyu Lu, Wenjian Ma","doi":"10.21037/acr-24-66","DOIUrl":"10.21037/acr-24-66","url":null,"abstract":"<p><strong>Background: </strong>Central retinal artery occlusion (CRAO) is a rare but critical complication that might appear after percutaneous coronary intervention (PCI) with a high risk of blindness. The report on the nursing management of CRAO patients after PCI is rare.</p><p><strong>Case description: </strong>This patient is a 50-year-old female patient who was admitted to the Cardiovascular Department with repeated chest tightness. Initial assessment diagnosed as unstable angina and received a PCI. The patient complained of white patches in the left eye and blurred vision ten minutes after returning to the ward. The nurse found patient's symptoms at once and reported to the attending doctor for the first time of diagnosis. Fundus photography results confirmed the diagnosis of CRAO. The patient received high-flow oxygen inhalation and hyperbaric oxygen chamber treatment for days. Nitroglycerin sublingual administration and nitroglycerin intravenous micropump were used to improve retinal microcirculation. Finally, arterial thrombolysis was given to remove the embolism in the central retinal artery. The nurse played an important role in disease observation, risk identification, early detection, cooperation with doctors, post-thrombolytic care, and psychological care. The patient's left eye vision showed significant recovery, and she was discharged successfully. The patient reported gradual improvement in left-eye vision during the follow-up assessment.</p><p><strong>Conclusions: </strong>This case report presents the interventions taken by nurses in early detection and care for a CRAO patient after PCI and expands the literature describing nursing management for patients with postoperative complications of PCI.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"7"},"PeriodicalIF":0.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transesophageal-echocardiography-guided one-stage TAVR + M-TEER credibly treated patients with severe double valve regurgitation: a case report.","authors":"Chunping Sun, Lai Wei, Lili Dong, Peng Zhu, Jun Lu, Zezhou Xiao, Shaoyi Zheng","doi":"10.21037/acr-24-71","DOIUrl":"10.21037/acr-24-71","url":null,"abstract":"<p><strong>Background: </strong>There are few reports about the one-stage surgery of transcatheter aortic valve replacement (TAVR) + mitral valve transcatheter edge-to-edge repair (M-TEER) around the world. TAVR + M-TEER surgery is usually performed under the simultaneous guidance of digital subtraction angiography (DSA) and echocardiography. There is no report of TAVR surgery assisted only by echocardiography all over the world. This case shows a novel one-stage transesophageal echocardiography-guided TAVR + M-TEER surgery, which provides a new idea for minimally invasive therapy.</p><p><strong>Case description: </strong>A 75-year-old man with recurrent chest tightness was diagnosed with bicuspid aortic valve malformation and severe regurgitation of aortic and mitral valves. The symptom was not relieved by medications. After evaluation with transthoracic echocardiography and computerized tomography angiography (CTA) of the aorta, transapical TAVR and M-TEER were performed simultaneously with satisfied clinical results. The patient's activity tolerance and cardiac function were improved.</p><p><strong>Conclusions: </strong>In the past, this surgery needs to be performed in a specific operating room equipped with an X-ray machine, and there are many steps in the whole procedure that requires more medical staff. Transesophageal echocardiography-guided minimally invasive valvular surgery reduces the reliance on the hybrid operating room, mitigates the impact of radiation on physicians and patients, and also provides a treatment chance for gravidas with valvular disease.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"16"},"PeriodicalIF":0.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Importance of the multidisciplinary approach in the surgical treatment of giant mediastinal neoplasms: a case series.","authors":"Giovanni Tacchi, Luca Frasca, Filippo Longo, Pierfilippo Crucitti","doi":"10.21037/acr-24-23","DOIUrl":"10.21037/acr-24-23","url":null,"abstract":"<p><strong>Background: </strong>Many reports described the importance of multidisciplinary meetings in providing oncologic patients with the best treatment strategies. This item improved overall survival, accuracy of staging and adherence to guidelines. For mediastinal neoplasms, collaboration between different surgical skills allows to deal with challenging/impossible surgical procedures. We report a series of four patients with a mediastinal-localized tumor with extensive infiltration of adjacent major structures. All cases were discussed at our multidisciplinary meeting where surgical indication was assessed. The presence of several surgical specialists, the role of anesthesiologists and sub-intensive clinicians was essential for proper operative and postoperative planning.</p><p><strong>Case description: </strong>A 70-year-old patient with type-A thymoma underwent a via sternotomy thymectomy with an end-to-end caval anastomosis and an end-to-side anastomosis with the left brachiocephalic trunk by prosthesis. A 52-year-old patient with malignant peripheral nerve sheath tumor of left sternocleidomastoid muscle underwent surgical excision and chest wall reconstruction by Teflon prosthesis and pedicled flap from the rectus abdominis. A 41-year-old woman diagnosed with monophasic synovial sarcoma of the anterior mediastinum. After chemotherapy without benefit, she underwent debulking surgery with excision of this huge mass and right phrenic nerve reconstruction by neural graft from the contralateral phrenic nerve. A 23-year-old woman affected by myasthenia gravis (MG) with a type-B3 thymoma diagnosis. After chemotherapy without benefit, she underwent a thymectomy and left pneumectomy with reconstruction of the superior vena cava (SVC).</p><p><strong>Conclusions: </strong>Multidisciplinary evaluation and surgical team are crucial in such complex cases to customize the most appropriate surgical planning and treatment.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"33"},"PeriodicalIF":0.7,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myeloperoxidase anti-neutrophil cytoplasmic antibody-associated vasculitis with silicosis, alveolar hemorrhage, and rapidly progressive glomerulonephritis: a case report.","authors":"Keiichi Mizuhashi","doi":"10.21037/acr-24-112","DOIUrl":"10.21037/acr-24-112","url":null,"abstract":"<p><strong>Background: </strong>The underlying pathophysiology of some occupational diseases such as silicosis involves autoantibodies. An autoantibody, antineutrophil cytoplasmic antibody (ANCA), has been recently reported and is known to be elevated in diseases such as vasculitis; therefore, the disease is currently known as ANCA-associated vasculitis. The risk of ANCA-associated vasculitis is known to be 25 times higher in patients with silicosis than in those without any occupational disease. In this report, the author describes the case of a man who developed ANCA-associated vasculitis after silicosis, leading to severe alveolar hemorrhage and renal dysfunction.</p><p><strong>Case description: </strong>A Japanese man in his 50s who was engaged in tunnel construction for 33 years presented with the chief complaint of cough with sputum. Based on chest images and his occupational history, a diagnosis of silicosis was made. In November 2008, urinary occult blood was detected; therefore, myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) levels were measured (15.9 U/mL). In September 2009, he experienced systemic fatigue, fever, night sweats, bloody sputum, and difficulty breathing. Chest images showed new shadows, and MPO-ANCA levels had increased to 690 U/mL. His bronchoalveolar lavage fluid was bloody, confirming alveolar hemorrhage. The bloody sputum resolved spontaneously; however, a subsequent short-term increase in serum creatinine levels was observed. Renal biopsy confirmed necrotizing crescentic glomerulonephritis. Therefore, he was diagnosed with MPO-ANCA-associated vasculitis with silicosis, alveolar hemorrhage, and rapidly progressive glomerulonephritis. Treatment with combination therapy of pulse methylprednisolone sodium succinate and cyclophosphamide led to remission.</p><p><strong>Conclusions: </strong>For patients with silicosis, accompanied by bloody sputum or other symptoms, ANCA-associated vasculitis, besides tuberculosis and lung cancer, should be considered. It is also necessary to pay close attention to the possible onset of rapidly progressive glomerulonephritis because it is sometimes fatal. In addition, when examining a patient with rapidly progressive glomerulonephritis, attention must be paid to whether the patient has had previous exposure to silica dust, regardless of whether or not the exposure was occupational.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"8"},"PeriodicalIF":0.7,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: co-infection of <i>Scedosporium</i> and <i>Mycobacterium</i> in lungs.","authors":"Chengying Liu, Weiwei Wu, Lan Wang, Jie Li","doi":"10.21037/acr-24-9","DOIUrl":"10.21037/acr-24-9","url":null,"abstract":"<p><strong>Background: </strong>There are hundreds of pathogens that cause lung infections. Compared to infections caused by a single pathogen, mixed infections account for a larger proportion of pulmonary infections and have a more severe clinical presentation, while treatment options differ between the two. We aimed to explore the advantages of metagenomic next-generation sequencing (mNGS) in the diagnosis and treatment of mixed infections.</p><p><strong>Case description: </strong>To investigate the specific pathogens in a 79-year-old male pneumonia patient who had recurrent cough with poor empirical treatment, we collected bronchoalveolar lavage fluid (BALF) from the patient and performed mNGS technology, along with Sanger sequencing and polymerase chain reaction (PCR) was carried out to confirm the authenticity of the pathogens detected by mNGS. The findings showed that rare pathogen <i>Scedosporium boydii</i> (<i>S. boydii</i>, reads: 18) and <i>Mycobacterium avium</i> complex (MAC, reads: 19) were detected, and the patient was subsequently transferred to another hospital for the same mNGS with the same results as the first detection. Therefore, combined treatment with voriconazole, ethambutol, azithromycin, and levofloxacin were given to the <i>S. boydii</i> and MAC for 1 week, and then patient's condition improved and discharged.</p><p><strong>Conclusions: </strong>mNGS, a non-targeted sequencing technology, could improve the efficiency of clinical diagnosis for mixed infection of rare or atypical pathogens, bring new ideas for clinical pathogen diagnosis, and improve patient prognosis.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"3"},"PeriodicalIF":0.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"30 years later-a case report of late surgical clip migration after laparoscopic cholecystectomy.","authors":"Mostafa Najim, Alexander Kusnik, Waail Rozi, Surinder Devgun","doi":"10.21037/acr-24-77","DOIUrl":"10.21037/acr-24-77","url":null,"abstract":"<p><strong>Background: </strong>Surgical clip migration is a rare complication that can happen many years following a successful cholecystectomy. It has a similar clinical presentation as choledocholithiasis. The diagnosis is usually made using imaging modalities such as ultrasounds, computed tomography (CT) scans, or magnetic resonance cholangiopancreatography (MRCP). If left untreated, complications such as acute cholangitis, acute pancreatitis, clip embolism, duodenal ulcer, and obstructive jaundice can develop. Endoscopic retrograde cholangiopancreatography (ERCP) is the therapeutic modality of choice for extracting the migrated clip with a high success rate. Surgical exploration is rarely required and reserved for complicated situations such as the presence of biliary stricture, fistula or concurrent large stones.</p><p><strong>Case description: </strong>We are presenting a case of a 51-year-old female who experienced a surgical clip migration 30 years after her laparoscopic cholecystectomy. The patient presented with abdominal pain and found to have deranged liver function test. Abdominal CT showed a dilated common bile duct (CBD) of 1.1 cm with a lodged metallic density within the CBD consistent with a surgical clip. ERCP was subsequently performed, which confirmed the presence of 1 cm free floating clip within the CBD.</p><p><strong>Conclusions: </strong>Laparoscopic cholecystectomy carries risk of late complications like surgical clip migration, and it should be considered as a differentia in patients presenting with picture of choledocholithiasis.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"5"},"PeriodicalIF":0.7,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of hyperammonemic encephalopathy induced by high-dose continuous infusion of 5-fluorouracil in a patient with rectal cancer.","authors":"Song Jin, Chaoming Dai, Wenpin Cai, Wei Bai, Jizhou Zhang","doi":"10.21037/acr-23-167","DOIUrl":"10.21037/acr-23-167","url":null,"abstract":"<p><strong>Background: </strong>Hyperammonemic encephalopathy caused by high-dose infusion of 5-fluorouracil (5-FU) is a rare adverse reaction in rectal cancer patients with an incidence rate of 5.7%. Although the patient could be restored to normal after supportive treatments, the occurrence of this side effect was still inevitable. Therefore, we analyzed the data of patients during chemotherapy and combined with relevant literature to provide reference for the prevention and treatment of hyperammonia-induced encephalopathy.</p><p><strong>Case description: </strong>The patient experienced severe consciousness disorders, unresponsive to stimuli, and stiff limbs during two cycles of 5-FU chemotherapy (after 40 hours of infusion), meanwhile the levels of blood ammonia were 117.0 and 349.0 µmol/L, lactate were 9.1 and 7.6 mmol/L respectively. The patient recovered consciousness and all of those laboratory indicators and vital signs turned to be normal through interrupting use of 5-FU and corresponding treatments after approximately 12 hours.</p><p><strong>Conclusions: </strong>Hyperammoniac encephalopathy was hard to prevent, we still recommended to conduct a comprehensive evaluation of the patient's physical condition including nutritional status, liver and kidney function, dihydropyrimidine dehydrogenase (DPD) level before chemotherapy in cases of muscle loss, infection or dehydration. In additional, therapeutic drug monitoring (TDM) can be considered to monitor blood drug concentration and guide the 5-FU dosage if possible. The early consciousness changes of patients during chemotherapy can remind us of prompt detection and treatment to avoid coma or even death.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"2"},"PeriodicalIF":0.7,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11761313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three episodes of basilar tip occlusion necessitating thrombectomies and a vertebral artery sacrifice in a patient with subclavian artery dissection distal to the vertebral artery origin: a case report.","authors":"Anat Horev, Tal Eliav, Nadav Biton, Yair Zlotnik, Asaf Honig, Alaa Bashir, Mohnnad Asla, Kseniia Shabad, Michael Star, Gal Ben-Arie","doi":"10.21037/acr-24-46","DOIUrl":"10.21037/acr-24-46","url":null,"abstract":"<p><strong>Background: </strong>While acute occlusion of the subclavian artery (SCA) proximal to the vertebral artery (VA) origin is an uncommon but recognized cause of embolic stroke, an occlusion distal to the VA is rare and can be easily overlooked.</p><p><strong>Case description: </strong>We describe the clinical presentation and evaluation of a previously healthy 56-year-old woman who experienced four life-threatening posterior circulation strokes within 1 month, three of which led to basilar artery (BA) occlusions requiring thrombectomies. Workup revealed an occlusion of the right SCA located less than 1 cm distal to the VA origin. After the fourth posterior circulation ischemic event and three BA thrombectomies, a decision was made to sacrifice the right VA origin. Following the sacrifice of the origin of the right VA, she recovered with minimal neurological deficits and regained complete functionality with no further ischemic episodes in the following 2 years.</p><p><strong>Conclusions: </strong>This case highlights an exceedingly rare etiology of posterior circulation stroke: an occlusion of the SCA distal to the VA origin. Though unconventional, the decision to sacrifice the VA origin proved crucial in this context and underscores the need for consideration in similar scenarios. Her recovery emphasizes the safety and effectiveness of recurrent thrombectomy procedures when appropriately indicated.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"6"},"PeriodicalIF":0.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual presentation and management of parathyroid carcinoma with pulmonary metastasis: a case report.","authors":"Hamad F Alrabiah, Thamer Althunayan, Hanan Almkainzi, Abdulaziz Alsalem, Mohammed Alessa","doi":"10.21037/acr-24-94","DOIUrl":"10.21037/acr-24-94","url":null,"abstract":"<p><strong>Background: </strong>Parathyroid carcinoma is a rare and challenging malignancy, often confirmed by histopathological analysis. Due to its rarity, it can present in atypically. We present a case of parathyroid carcinoma with an unusual course of pulmonary metastasis emphasizing the complexities of its diagnosis and management.</p><p><strong>Case description: </strong>A 38-year-old lady was referred to our department when her newborn was found to have hypoparathyroidism. Laboratory tests showed elevated parathyroid hormone (PTH) and adjusted calcium levels. Imaging studies suggested the presence of parathyroid tumors, and histopathology confirmed parathyroid carcinoma. Immunohistochemistry was positive for GATA3 in the tumor cells, and next generation sequencing revealed CDC73 mutation, MYC rearrangement, ASXL1 mutation, and a tumor mutational burden (TMB) of 11 Muts/Mb. Despite surgical intervention and initial remission, she developed pulmonary metastasis, which was surgically addressed. She is currently under immunotherapy with six cycles of pembrolizumab due to recurrence.</p><p><strong>Conclusions: </strong>This case highlights the importance of prolonged surveillance and imaging for parathyroid carcinoma due to recurrence and metastasis. Aggressive resection of parathyroid carcinoma and metastasis are important to decrease mortality. This case also highlights the importance of genetic factors, like CDC73 mutations, confirmed in this study.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"9 ","pages":"4"},"PeriodicalIF":0.7,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760510/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Collision tumor of the cecum and ileocecal valve composed of mucinous adenocarcinoma and neuroendocrine tumor: a case report.","authors":"Leslie R Elmore, Alexandra Drymon, Angel Toca, Andrei I Gritsiuta, William Gilleland","doi":"10.21037/acr-24-87","DOIUrl":"https://doi.org/10.21037/acr-24-87","url":null,"abstract":"<p><strong>Background: </strong>Collision tumors of the gastrointestinal (GI) tract are thought to be uncommon, with those of the colon being rare with very few cases reported in current literature. There are three proposed theories regarding the etiology of collision tumors currently, including the \"double primaries\", the \"biclonal malignant transformation\", and the \"tumor-to-tumor carcinogenesis\" theories. Prognosis of collision tumors remains unclear. To our knowledge, this is the fifth case of a collision carcinoma involving the cecum and ileocecal valve and the first report of a collision carcinoma including both mucinous adenocarcinoma and neuroendocrine tumor of the cecum and the ileocecal valve. The aim of this paper is to explore the history of collision tumors and associated nomenclature, defined diagnostic criteria, and proposed theories for etiology in addition to patient presentation, approach to diagnosis, treatment options, and prognosis.</p><p><strong>Case description: </strong>We present the case of an 83-year-old female who presented to the emergency room with a 4-month history of cramping abdominal pain associated with nausea, emesis, and decreased appetite with associated weight loss. Diagnostic imaging demonstrated a bowel obstruction secondary to a mass in the cecum and she underwent an exploratory laparotomy with right hemicolectomy. She was found to have a collision carcinoma of the cecum and ileocecal valve containing both mucinous adenocarcinoma and neuroendocrine tumor. Diagnosis was confirmed post-operatively with pathologic examination and immunohistochemical testing.</p><p><strong>Conclusions: </strong>Diagnosing collision tumors upon patient presentation is exceedingly difficult as the symptoms are often identical to other neoplasms of the GI tract and vary based on location of the tumor. It is thought that the true prevalence of collision tumors is underestimated due to history of changing nomenclature, unclear diagnostic criteria, unreported cases, and unrecognized cases. Furthermore, new advances in immunohistochemical evaluation have allowed for better characterization of these neoplasms. With clarification regarding nomenclature, diagnostic criteria and expanding awareness, it is our hope that this leads to an increase in reported cases, allowing for an expanded discussion and resulting growth of literature and further studies. Further knowledge regarding the pathogenesis, treatment, and prognosis is needed.</p>","PeriodicalId":29752,"journal":{"name":"AME Case Reports","volume":"8 ","pages":"109"},"PeriodicalIF":0.7,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11459393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}