International Journal of Cardiology Cardiovascular Risk and Prevention最新文献

{"title":"From analysis to action: Confronting regional IHD mortality inequities","authors":"Jonathan James O. Canete","doi":"10.1016/j.ijcrp.2025.200478","DOIUrl":"10.1016/j.ijcrp.2025.200478","url":null,"abstract":"<div><div>This correspondence paper engages critically with the study titled <em>“Three-decade analysis of regional disparities in metabolic risk factor related ischemic heart disease mortality: Contrasting trends between South Asia and North America.”</em> The study presents a comprehensive long-term analysis of ischemic heart disease (IHD) mortality trends, revealing increasing mortality rates in South Asia despite similar metabolic risk factor burdens compared to declining rates in North America. While commendable in its scope and rigor, the study could have explored additional social determinants of health, including socioeconomic inequality, education, and healthcare accessibility, to better explain regional disparities. Furthermore, the reliance on aggregated data without stratification by gender, socioeconomic status, or urban-rural differences limits the study's applicability for developing targeted interventions. This correspondence advocates for integrating these factors into future analyses and calls for actionable, regionally tailored policy recommendations to address IHD mortality inequities. Overall, the paper underscores the need for equity-focused strategies that translate epidemiological insights into effective and contextually relevant public health interventions.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200478"},"PeriodicalIF":2.1,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Barriers and facilitators to the uptake of the Ischaemia with Non-Obstructive Coronary Arteries (INOCA) recommendation by cardiologists in the Netherlands: A qualitative study","authors":"Linda Modderkolk ,&nbsp;Irene Göttgens ,&nbsp;Lori van den Hurk ,&nbsp;Sabine Oertelt-Prigione","doi":"10.1016/j.ijcrp.2025.200480","DOIUrl":"10.1016/j.ijcrp.2025.200480","url":null,"abstract":"<div><h3>Background</h3><div>Ischemia with No Obstructive Arteries (INOCA) is a condition characterized by an elusive diagnosis and a significant impact on patients' quality of life. Recent evidence challenges previous assumptions about INOCA's benign prognosis, emphasizing the increased downstream risks associated with condition. A 2020 Dutch Society for Cardiology (NVVC) recommendation aims to guide cardiologists in the management of INOCA, but its adoption in practice varies. This study explores the interconnecting factors influencing the uptake of the INOCA recommendation.</div></div><div><h3>Methods</h3><div>A qualitative interview study was performed to investigate cardiologists' adoption of the 2020 NVVC INOCA recommendation in the Netherlands, utilizing the Theoretical Domains Framework and COM-B model. A diverse sample of Dutch cardiologists was recruited and digital semi-structured interviews were conducted and analyzed using directed content analysis.</div></div><div><h3>Results</h3><div>A total of 14 Dutch cardiologists (6 women, 8 men) was interviewed to explore factors influencing their uptake of the 2020 NVVC INOCA recommendation. The immediate influences on uptake were grouped into three domains: capabilities, opportunities, and motivation according to the COM-B model. Most importantly, underlying assumptions about the evidence base, diagnostic accuracy, and gendered stereotypes significantly influenced recommendation uptake.</div></div><div><h3>Conclusions</h3><div>Underlying assumptions about the disease entity and the affected patient, which are seldom investigated in implementation research, significantly affect the overall uptake of the INOCA guideline. Careful investigation of these assumptions is necessary to challenge them and foster an environment conducive to the uptake of structural implementation measures.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200480"},"PeriodicalIF":2.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: “Dyslipidemia and cerebral atrophy among health check-up individuals: A cross-sectional study”","authors":"Parth Aphale,&nbsp;Shashank Dokania,&nbsp;Himanshu Shekhar","doi":"10.1016/j.ijcrp.2025.200481","DOIUrl":"10.1016/j.ijcrp.2025.200481","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200481"},"PeriodicalIF":2.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144757976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: Comments on gender differences in acute heart failure study","authors":"Çağrı Zorlu,&nbsp;Sefa Erdi Ömür","doi":"10.1016/j.ijcrp.2025.200477","DOIUrl":"10.1016/j.ijcrp.2025.200477","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200477"},"PeriodicalIF":1.9,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144704542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can psychological interventions affect cardiac rehabilitation patients’ well-being? Preliminary results from a longitudinal study","authors":"Elisa Zambetti ,&nbsp;Maura Crepaldi ,&nbsp;Fiorella Lanfranchi ,&nbsp;Emanuela Zenoni ,&nbsp;Irene Bariletti ,&nbsp;Francesco Quarenghi ,&nbsp;Luigina Viscardi ,&nbsp;Ginevra Rizzola ,&nbsp;Valentina Regazzoni ,&nbsp;Alessandra Bigoni ,&nbsp;Francesca Brivio ,&nbsp;Irma Maria Soddu ,&nbsp;Massimiliano Anselmi Kaiser ,&nbsp;Vittorio Giudici ,&nbsp;Andrea Greco","doi":"10.1016/j.ijcrp.2025.200474","DOIUrl":"10.1016/j.ijcrp.2025.200474","url":null,"abstract":"<div><h3>Background</h3><div>Research has explored the link between psychological factors and cardiovascular diseases [CVDs], with a focus on identifying predictors of these disorders. Cardiac Rehabilitation [CR] is crucial for heart disease patients, particularly those with psychological comorbidities, as it helps in self-care and understanding their condition. This study aims to compare the psychological health of CVD patients – in terms of anxiety, depression, and illness perception – before (baseline, T0) and after (over time, T1) multidisciplinary cardiac rehabilitation treatment, considering the effects of different psychological interventions (psychoeducational group, progressive muscle relaxation training, and individual counseling).</div></div><div><h3>Methods</h3><div>A total of 181 patients with acute coronary syndrome [ACS], cardiac decompensation [CD], or cardiac surgery [CS], participated in a rehabilitation program between January and August 2023. Self-report questionnaires were used to investigate levels of anxiety, depression (Hospital Anxiety and Depression Scale), and illness perception (Brief Illness Perception Questionnaire) at T0 and T1.</div></div><div><h3>Results</h3><div>Statistically significant changes were found over time. Individual counseling led to significant reductions in depression and anxiety, and improved illness perception. Anxiety levels were also influenced by the type of cardiovascular disease and by the presence or absence of physical comorbidity.</div></div><div><h3>Conclusions</h3><div>The study highlights significant improvements in levels of anxiety, depression, and illness perception from T0 to T1. Individual counseling is the most high-impact psychological intervention. These findings show the importance of psychological interventions in enhancing CVD patients’ psychological and physical well-being.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200474"},"PeriodicalIF":1.9,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144687231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inadequacy of coronary calcium scoring in evaluating coronary artery disease: A call to shifting to high-resolution CT coronary imaging","authors":"Jonathan Mokhtar ,&nbsp;Mohammad Albaree ,&nbsp;Virginia Battistin ,&nbsp;Mohamed Asbaita ,&nbsp;Fatemeh Akbarpoor ,&nbsp;Jeyaseelan Lakshmanan ,&nbsp;Hassan El-Tamimi","doi":"10.1016/j.ijcrp.2025.200476","DOIUrl":"10.1016/j.ijcrp.2025.200476","url":null,"abstract":"<div><h3>Background and aims</h3><div>Coronary artery calcium (CAC) scoring is an increasingly adopted, non-invasive modality for assessing coronary artery disease (CAD). However, its diagnostic reliability in comparison to invasive coronary angiography (ICA) remains controversial. This study evaluated the diagnostic performance of CAC scoring in predicting CAD using ICA as the reference.</div></div><div><h3>Methods</h3><div>Adults who underwent both coronary computed tomography angiography (CCTA) with CAC scoring and ICA within a three-month interval were retrospectively analyzed between 2018 and 2024. Obstructive CAD was defined as ≥ 50% stenosis on ICA. Patients were stratified by CAC scores: 0 (group 1), 1–399 (group 2), and ≥400 (group 3). Chi-square analysis was utilized to assess the differences in CAC scores compared to ICA. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of CAC against ICA were all calculated using R version 4.4.0.</div></div><div><h3>Results</h3><div>Among 110 patients (mean age 53 ± 10; 86.4% males), obstructive CAD was found in 25% of patients in group 1, 56% of patients in group 2, and 79% of patients in group 3 (χ² = 14.21, <em>p</em> &lt; 0.001). CAC demonstrated a sensitivity of 91.2%, specificity of 63.2%, a PPV of 92.2%, and an NPV of 60%.</div></div><div><h3>Conclusion</h3><div>While a CAC score of 400 or higher strongly predicts significant CAD, scores of zero or intermediate values fail to exclude obstructive disease reliably. These findings reaffirm that CAC scoring is a useful stratification tool but should be interpreted with caution, particularly in high-risk patients, and confirmed with ICA when appropriate.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200476"},"PeriodicalIF":1.9,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144670839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiography-derived index of microcirculatory resistance as risk stratification tool in dilated cardiomyopathy","authors":"Ioannis Skalidis ,&nbsp;Philippe Garot ,&nbsp;Mariama Akodad ,&nbsp;Stephane Cook ,&nbsp;Panagiotis Antiochos","doi":"10.1016/j.ijcrp.2025.200473","DOIUrl":"10.1016/j.ijcrp.2025.200473","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200473"},"PeriodicalIF":1.9,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elevated serum glutathione peroxidase levels reducing the risk of acute upper gastrointestinal bleeding combined with acute coronary syndrome: Evidence from observational, interventional, and Mendelian randomization studies","authors":"Weibo Zhang,&nbsp;Hailing Zhang","doi":"10.1016/j.ijcrp.2025.200471","DOIUrl":"10.1016/j.ijcrp.2025.200471","url":null,"abstract":"<div><h3>Background</h3><div>Acute upper gastrointestinal hemorrhage (UGIH) combined with acute coronary syndrome (ACS) poses a significant clinical challenge linked to oxidative stress, while elevated serum glutathione peroxidase (GSH-Px) levels may provide a protective effect.</div></div><div><h3>Methods</h3><div>A two-phase study was conducted. First, Mendelian randomization (MR) analysis using three GSH-Px-associated SNPs (rs6993770, rs1097234, rs4149991) was performed to assess causality between genetically predicted GSH-Px activity and UGIH-ACS risk, leveraging public GWAS data. Second, a randomized, double-blind, placebo-controlled trial (RCT) enrolled UGIH-ACS patients (n = 110) to received oral selenium (200 μg/day) or placebo for 8 weeks. Comparisons were made with a UGIH-only control group (n = 78) and healthy controls (n = 83). Serum GSH-Px levels, 90-day mortality, rebleeding rates, and major adverse cardiovascular events (MACE) were analyzed.</div></div><div><h3>Results</h3><div>MR analysis showed no significant causal link between GSH-Px activity and UGIH-ACS risk (IVW OR: 0.966, 95 % CI: 0.873–1.069, p = 0.502), but the weighted median method suggested a marginal protective trend (OR: 0.958, 95 % CI: 0.918–1.000, p = 0.048). Sensitivity analyses confirmed robust estimates with low heterogeneity. In the RCT, selenium supplementation significantly increased GSH-Px levels (+51.9 % vs. +6.0 %, p &lt; 0.001), reduced 90-day rebleeding (12.0 % vs. 22.7 %, p = 0.014), and lowered MACE risk (9.1 % vs. 21.8 %, p = 0.042).</div></div><div><h3>Conclusion</h3><div>While MR analysis found no strong causal link between GSH-Px activity and UGIH-ACS risk, the weighted median method indicated a marginal protective trend, underscoring GSH-Px's role in oxidative stress modulation. Selenium supplementation significantly increased GSH-Px activity (+51.9 %, p &lt; 0.001), reduced rebleeding, and lowered MACE risk, supporting its potential as adjunctive therapy for UGIH-ACS and warranting further investigation into additional mechanisms.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200471"},"PeriodicalIF":1.9,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors of acute coronary syndrome among patients admitted to cardiac care units at governmental hospitals in the Gaza Strip: Case- control study","authors":"Tareq Khattab ,&nbsp;Yousef Aljeesh","doi":"10.1016/j.ijcrp.2025.200466","DOIUrl":"10.1016/j.ijcrp.2025.200466","url":null,"abstract":"<div><h3>Background</h3><div>Acute coronary syndrome represents a major global health issue. The aim of the study was to identify the risk factors related to acute coronary syndrome among patients admitted to cardiac care units in governmental hospitals in the Gaza Strip.</div></div><div><h3>Methods</h3><div>An analytical case-control study was conducted from February to September 2023, involving 300 participants (100 cases and 200 controls) selected by quota sampling from governmental hospitals in the Gaza Strip. The data were collected using structured interviews and questionnaires. Reliability testing by Cronbach's alpha coefficient (0.87) and statistical analysis was conducted using SPSS version 25.</div></div><div><h3>Result</h3><div>Among the participants, 78 % were male while 22 % were female. 30 % fell into the age group of 56–60 years, and 34 % received treatment at Al Shifa Medical Complex. The logistic regression analysis revealed several significant risk factors associated with acute coronary syndrome. These included lower income (OR = 2.32, 95 % CI: 1.36–3.94, p = 0.002) and family history of acute coronary syndrome (OR = 5.46, 95 % CI: 3.24–9.19, p &lt; 0.001). smoking (OR = 4.38, 95 % CI: 2.62–7.34, p &lt; 0.001). A history of hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, and NSAID drug use is associated with acute coronary syndrome, overweight (OR = 2.86, 95 % CI: 1.58–5.19, p = 0.001), obesity (OR = 6.74, 95 % CI: 3.30–13.78, p &lt; 0.001), higher waist-to-height ratio (OR = 3.75, 95 % CI: 1.62–8.66, p = 0.002), and waist-to-hip ratio (OR = 5.07, 95 % CI: 2.64–9.71, p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>This study highlights lower income and familial predisposition as critical acute coronary syndrome predictors in Gaza, alongside traditional risks like obesity and smoking. Implementing strategies to control these risk factors and improve preventive measures is crucial for reducing the incidence of acute coronary syndrome.</div></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"26 ","pages":"Article 200466"},"PeriodicalIF":1.9,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144655169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correspondence: Risk assessment and prevention of cardiovascular events in patients with obstructive sleep apnea syndrome: A narrative review","authors":"Muhammad Ismail ,&nbsp;Shad Khan ,&nbsp;Sadaqat Ullah Rehmat ,&nbsp;Farman Ullah Khan","doi":"10.1016/j.ijcrp.2025.200470","DOIUrl":"10.1016/j.ijcrp.2025.200470","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"27 ","pages":"Article 200470"},"PeriodicalIF":2.1,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144894980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}