International Journal of Cardiology Cardiovascular Risk and Prevention最新文献

{"title":"Corrigendum to “Impact of heart failure severity and major bleeding events after percutaneous coronary intervention on subsequent major adverse cardiac events” [Int. J. Cardiol. Cardiovasc. Risk and Prev. 2023 Jun 25:18:200193]","authors":"So Ikebe , Masanobu Ishii , Yasuhiro Otsuka , Taishi Nakamura , Kenichi Tsujita , Tetsuya Matoba , Takahide Kohro , Yusuke Oba , Tomoyuki Kabutoya , Yasushi Imai , Kazuomi Kario , Arihiro Kiyosue , Yoshiko Mizuno , Kotaro Nochioka , Masaharu Nakayama , Takamasa Iwai , Yoshihiro Miyamoto , Hisahiko Sato , Naoyuki Akashi , Hideo Fujita , Ryozo Nagai","doi":"10.1016/j.ijcrp.2024.200304","DOIUrl":"10.1016/j.ijcrp.2024.200304","url":null,"abstract":"","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200304"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000692/pdfft?md5=443f6f9998071e71cb1e4d4ec231de9f&pid=1-s2.0-S2772487524000692-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141708366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of uncontrolled hypertension among type 2 diabetic patients in Ethiopia: Multicenter cross-sectional study","authors":"Leteslase Hagos Gebreziher ,&nbsp;Melak Gedamu Beyene ,&nbsp;Desalew Mekonnen ,&nbsp;Assefa Mulu Baye","doi":"10.1016/j.ijcrp.2024.200308","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200308","url":null,"abstract":"<div><h3>Background</h3><p>Hypertension (HTN) is the commonest comorbidity among people with type 2 diabetes mellitus (T2DM). Uncontrolled HTN is a major risk factor for several diseases. This study aimed to determine the magnitude and predictors of uncontrolled HTN among T2DM patients.</p></div><div><h3>Methods</h3><p>A multicenter cross-sectional study was conducted among hypertensive from September 19, 2021 to 17 December 2021. Logistic regression model was conducted to identify predictors of uncontrolled HTN. Uncontrolled BP was defined by systolic BP of ≥130 mmHg and/or diastolic BP of ≥80 mmHg.</p></div><div><h3>Results</h3><p>A total of 400 study participants were included in the analysis, of which 208 (52 %) were females. The mean age of the participants was 60.6 with SD of 10.25 years. The target blood pressure achieved in 156 (39 %) of participants. Age, non-adherence to medications (OR; 2.0; 95 % CI: 1.1–3.6; P = 0.02), not reducing dietary salt (OR; 2.4; 95 % CI: 1.5–3.8; P &lt; 0.001), uncontrolled blood sugar (OR:2.4; 95 % CI: 1.4–4.3; P = 0.002), obesity (OR; 3.2; 95 % CI:1.2–8.7; P = 0.03) and having every fourth month and above follow up (OR; 2.3; 95 % CI:1.3–4.3; P = 0.049) were significantly associated with uncontrolled blood pressure.</p></div><div><h3>Conclusions</h3><p>The target blood pressure achieved was suboptimal. Hypertensive T2DM patients who were younger, non-adherent to their medications, not reducing dietary salt, obese, with a longer frequency of follow-up, and with poor glycemic control were more likely to have uncontrolled blood pressure. Improving medication adherence, dietary salt reduction, frequent follow up and glycemic control are important to control hypertension.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200308"},"PeriodicalIF":1.9,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000734/pdfft?md5=5bc5eb22de402c6c95605223cedb6c56&pid=1-s2.0-S2772487524000734-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141542928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal trends in acute decompensated heart failure outcomes: A single-center 11-year retrospective analysis","authors":"Gil Marcus ,&nbsp;Mohammad Najjar ,&nbsp;Antionette Monayer ,&nbsp;Ady Orbach ,&nbsp;Shiri L. Maymon ,&nbsp;Eran Kalmanovich ,&nbsp;Gil Moravsky ,&nbsp;Avishay Grupper ,&nbsp;Shmuel Fuchs ,&nbsp;Sa'ar Minha","doi":"10.1016/j.ijcrp.2024.200306","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200306","url":null,"abstract":"<div><h3>Background</h3><p>Acute Decompensated Heart Failure (ADHF) is associated with frequent hospitalizations, posing a significant health and economic burden globally. Despite advancements in heart failure management, studies delineating temporal trends in ADHF outcomes are sparse.</p><p>Methods: in this retrospective analysis, ADHF patients admitted to Shamir Medical Center from 2007 to 2017 were categorized into two cohorts: early (2007–2011) and recent (2012–2017). Clinical characteristics, in-hospital interventions, and outcomes were compared. Survival analysis was performed using Kaplan-Meier methods with log-rank tests.</p></div><div><h3>Results</h3><p>8332 admitted patients were analyzed, 4366 (52.4 %) in the early period, and 3966 (47.6 %) in the recent period. In the recent cohort, ischemic heart disease decreased significantly (from 45.2 % to 34.7 %), while hypertension and smoking rates increased. Additionally, a significant increase in coronary artery bypass grafting (from 0.8 % to 3.5 %) and beta-blockers prescription (from 45.5 % to 63.4 %) post-discharge was observed. However, no substantial improvement in in-hospital mortality (8.9 % in early vs. 8.0 % in recent), 30-day (3.2 % in early vs. 3.1 % in recent), 1-year (23.3 % in early vs. 23.8 % in recent), or 5-year survival rates was noted between cohorts. A subset analysis of patients admitted to cardiology departments showed a significant reduction in in-hospital mortality in the recent cohort (12.3 % in early vs. 6.3 % in recent), yet without a corresponding long-term survival benefit.</p></div><div><h3>Conclusions</h3><p>Advancements in heart failure management over the 11-year study period did not demonstrate an improvement in clinical outcomes for ADHF patients, highlighting the challenge of translating advancements in the medical care of ADHF patients into long-term survival benefits.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200306"},"PeriodicalIF":1.9,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000710/pdfft?md5=d39564b9ef9ea497e9696c75470623e1&pid=1-s2.0-S2772487524000710-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141542871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distinct circulating cytokine levels in patients with angiography-proven coronary artery disease compared to disease-free controls","authors":"Eveliina Maaniitty ,&nbsp;Sami Sinisilta ,&nbsp;Juho Jalkanen ,&nbsp;Tuija Vasankari ,&nbsp;Fausto Biancari ,&nbsp;Jarmo Gunn ,&nbsp;Sirpa Jalkanen ,&nbsp;K.E. Juhani Airaksinen ,&nbsp;Maija Hollmén ,&nbsp;Tuomas Kiviniemi","doi":"10.1016/j.ijcrp.2024.200307","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200307","url":null,"abstract":"<div><h3>Background</h3><p>Systemic inflammation has a critical role in the development of symptomatic coronary artery disease (CAD). Identification of inflammatory pathways may provide a platform for novel therapeutic approaches. We sought to determine whether there are differences in circulating cytokine profiles between patients with CAD and disease-free controls as well as according to the severity of the disease.</p></div><div><h3>Methods</h3><p>Case-control study's population consisted of 452 patients who underwent diagnostic invasive coronary angiography due to clinical indications. We measured the serum concentrations of 48 circulating cytokines. Extent of CAD was assessed using the SYNTAX Score in 116 patients. Cytokine differences between groups were tested using Mann-Whitney <em>U</em> test and associations with CAD were explored using a logistic regression model.</p></div><div><h3>Results</h3><p>Overall, 310 patients had angiographically verified CAD whereas 142 had no angiographically-detected coronary atherosclerosis. In multivariable logistic regression models adjusted for age, sex, hypertension, atrial fibrillation, history of smoking and treatment for diabetes and hyperlipidemia, increased levels of interleukin 9 (OR 1.359, 95%CI 1.046–1.766, <em>p</em> = 0.022), IL-17 (1.491, 95%CI 1.115–1.994, <em>p</em> = 0.007) and tumor necrosis factor alpha (TNF-α) (OR 1.440, 95%CI 1.089–1.904, <em>p</em> = 0.011) were independently associated with CAD. Patients with SYNTAX Score&gt;22 had increased levels of stromal cell-derived factor 1 alfa (SDF-1α), beta-nerve growth factor (β-NGF), IL-3 and decreased level of IL-17 compared to those with score ≤22 when adjusted for smoking and use of beta-blockers.</p></div><div><h3>Conclusions</h3><p>Patients with CAD have distinct circulating cytokine profiles compared to disease-free controls. Distinct cytokines may have pivotal roles at different stages of coronary atherosclerosis. <span>ClinicalTrials.gov</span><svg><path></path></svg> Identifier: NCT03444259 (<span>https://clinicaltrials.gov/study/NCT03444259</span><svg><path></path></svg>).</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200307"},"PeriodicalIF":1.9,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000722/pdfft?md5=3c2869e4ce91881c6183f5789fa858b5&pid=1-s2.0-S2772487524000722-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141596165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myocardial infarction & C-reactive protein levels among Mexican adults with arthritis: Findings from the Mexican Health and Aging Study","authors":"Alan F. Villarreal Rizzo ,&nbsp;Elizabeth I. Davis ,&nbsp;Wissam I. Khalife ,&nbsp;M. Kristen Peek ,&nbsp;Brian Downer","doi":"10.1016/j.ijcrp.2024.200309","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200309","url":null,"abstract":"<div><h3>Background</h3><p>Studies of adult populations in high-income countries have found an association between arthritis and myocardial infarction (MI) due to high levels of systemic inflammation. Our objectives were to examine the association between arthritis and MI among Mexican adults and to assess the mediating effect of C-reactive protein (CRP) on this association.</p></div><div><h3>Methods</h3><p>Data came from the 2012, 2015, and 2018 observation waves of the Mexican Health and Aging Study. Our sample included 11,707 participants aged 50 and older with no prior MI before 2012. We used self-reported information for arthritis, joint pain, medication use, and limitations to daily activities in 2012. Logistic regression was used to model the association between arthritis and self-reported MI in 2015 or 2018. We used a sub-sample of 1602 participants to assess the mediating effect of CRP.</p></div><div><h3>Results</h3><p>In the full sample, participants with arthritis that limited their daily activities had higher odds of MI than participants with no arthritis (OR = 1.40; 95 % CI = 1.04–1.88). In the sub-sample, arthritis that limited daily activities was associated with higher mean CRP (5.2 mg/dL; 95 % CI = 4.10–6.21) than arthritis with no limitations (3.5 mg/dL; 95 % CI = 2.93–4.01). However, CRP levels had a small mediating effect, and the relationship between arthritis with physical limitations and MI remained statistically significant.</p></div><div><h3>Conclusion</h3><p>Mexican adults with arthritis that limits their daily activities are at an increased risk for MI. Continued research is needed to identify factors that contribute to this increased risk.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200309"},"PeriodicalIF":1.9,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000746/pdfft?md5=16b93f4385fc33b3cd0c511b237d8b16&pid=1-s2.0-S2772487524000746-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141542929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex-specific associations between prolonged serum uric acid levels and risk of major adverse cardiovascular events","authors":"Hsiu-Ting Chien ,&nbsp;Yu-Wen Lin ,&nbsp;Li-Jiuan Shen ,&nbsp;Song-Chou Hsieh ,&nbsp;Lian-Yu Lin ,&nbsp;Yi-An Chen ,&nbsp;Fang-Ju Lin","doi":"10.1016/j.ijcrp.2024.200302","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200302","url":null,"abstract":"<div><h3>Background</h3><p>While hyperuricemia has been correlated with cardiovascular (CV) diseases, further evidence is required to evaluate the implications of stable serum uric acid (sUA) levels, especially concerning low sUA. This study aimed to investigate prolonged stable sUA levels and CV events/mortality.</p></div><div><h3>Methods</h3><p>We conducted a retrospective cohort study at a medical center using electronic medical records linked with the national claims database. Patients with at least two sUA measurements, with intervals ranging from 6 months to 4 years, were included. The mean of the first two eligible sUA measurements were analyzed, stratified by sex. Outcomes of interest comprised major adverse cardiovascular events (MACE), heart failure hospitalization, CV and all-cause mortality.</p></div><div><h3>Results</h3><p>This study included 33,096 patients (follow-up: men 6.6 years, women 6.4 years). After multivariable adjustment, cubic spline models showed that long-term high sUA levels were consistently associated with a higher risk of MACE, heart failure hospitalization, CV and all-cause mortality. A U-shaped association was observed between sUA levels and all-cause mortality in both sexes and between sUA levels and CV mortality in women. The impact of sUA, especially lower levels, on CV events and mortality was more pronounced in women than in men.</p></div><div><h3>Conclusion</h3><p>Long-term high sUA levels are consistently associated with increased risk of CV events and mortality. A U-shaped association between sUA levels and all-cause mortality was observed in both men and women and was pronounced in women. The findings underscore the importance of considering sUA levels, especially in women, when assessing CV risk.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200302"},"PeriodicalIF":1.9,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000679/pdfft?md5=ede070c0ce1ee0a2af145d4bde585efc&pid=1-s2.0-S2772487524000679-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of overweight and obesity with coronary risk factors and the presence of multivessel disease in patients with obstructive coronary artery disease – A nationwide registry study","authors":"Maria Hang Xuan Pham ,&nbsp;Daniel Mølager Christensen ,&nbsp;Andreas Torp Kristensen ,&nbsp;Charlotte Middelfart ,&nbsp;Caroline Sindet-Pedersen ,&nbsp;Gunnar Gislason ,&nbsp;Niels Thue Olsen","doi":"10.1016/j.ijcrp.2024.200299","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200299","url":null,"abstract":"<div><h3>Background</h3><p>The growing prevalence of obesity is expected to increase the burden of coronary artery disease. This study examined the prevalence of overweight and obesity in patients with a first-time diagnosis of obstructive coronary artery disease in a contemporary population. The association of body-mass-index (BMI) with age, traditional risk factors, and the presence of multivessel disease were explored.</p></div><div><h3>Methods and results</h3><p>Using the Danish Nationwide registries, we identified 49,733 patients with a first-time diagnosis of obstructive coronary artery disease in the period 2012–2018. We investigated the association between BMI and coronary risk factors by multivariate logistic regression. Mean age was 65.8 ± 11.8 years, mean BMI was 27.5 kg/m² ± 7.2, and 73.2 % were men. 66.3 % had a BMI ≥25 kg/m² and 1.3 % were underweight. The prevalence of patients with BMI ≥25 kg/m² decreased with increasing age and was 69 % in patients &lt;50 year vs. 46.2 % in patients ≥80 years (<em>p &lt; 0.001</em>). In all age groups, higher odds of BMI ≥25 kg/m² were observed in males, former smokers, and patients with hypertension. In multivariate logistic regression, BMI ≥25 kg/m² was not associated with presence of multivessel disease <em>(p = 0.74)</em>.</p></div><div><h3>Conclusion</h3><p>In this large, nationwide study, 66.3 % of patients with first time diagnosis of obstructive coronary disease had BMI ≥25 kg/m². Young patients had higher BMI and were more likely to be current smokers. Overweight or obesity was independently associated with the presence of diabetes and hypertension. BMI ≥25 kg/m² was not independently associated with the presence of multivessel disease.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200299"},"PeriodicalIF":1.9,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000643/pdfft?md5=85024e12e26730f89f6d0708190e1d1b&pid=1-s2.0-S2772487524000643-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141434189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonepisodic angioedema with eosinophilia following a rose-thorn prick injury","authors":"Kimitoshi Matsuo ,&nbsp;Hidenori Takahashi ,&nbsp;Hiroki Nagamatsu ,&nbsp;Ryutaro Hirose ,&nbsp;Yuka Yamada ,&nbsp;Hiroaki Takei ,&nbsp;Naoya Toba ,&nbsp;Mio Toyama-Kousaka ,&nbsp;Shinichiro Ota ,&nbsp;Miwa Morikawa ,&nbsp;Masaharu Shinkai","doi":"10.1016/j.ijcrp.2024.200301","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200301","url":null,"abstract":"<div><h3>Background</h3><p>Nonepisodic angioedema with eosinophilia (NEAE) is a condition marked by angioedema and significant eosinophilia and often linked with atopic dermatitis. It predominantly affects young Asian women and occurs more frequently in the autumn and winter. Despite over 100 reported cases, its etiology and pathogenesis remain unclear.</p></div><div><h3>Case presentation</h3><p>A 23-year-old Japanese female florist presented with acute arm swelling following rose-thorn pricks to her hands and fingers in spring. One week later, she developed progressive symmetrical non-pitting edema in her lower legs and a 3 kg weight gain without any rash. She had a history of oral allergy syndrome to apples and pears for which allergen-specific IgE were previously detected. Blood tests showed significant eosinophilia (14,930 cells/μL) and elevated thymus and activation-regulated chemokine (TARC) levels (12,864 pg/mL). Thyroid disease, autoimmune disorders, and hematologic malignancies were ruled out. Normal cardiac markers and a whole-body computed tomography excluded visceral organ involvement. She was diagnosed with NEAE and treated with oral prednisolone, which resolved the edema within 10 days. Prednisolone was tapered gradually on an outpatient basis without recurrence.</p></div><div><h3>Conclusion</h3><p>A review of the literature indicates that NEAE triggered by subcutaneous antigen exposure may not follow the typical age or seasonal patterns. Direct subcutaneous antigen exposure, including rose-thorn pricks, can trigger NEAE. Clinicians should consider NEAE in atypical presentations and thoroughly investigate preceding episodes.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200301"},"PeriodicalIF":2.3,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000667/pdfft?md5=6b57b831709599dd537cdfa177f294c2&pid=1-s2.0-S2772487524000667-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141423678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary hypertension exacerbated by hereditary hemorrhagic telangiectasia combined with pulmonary arteriovenous fistula and pregnancy status: A case report","authors":"Wanjiao Chen ,&nbsp;Yuliang Long ,&nbsp;Dandan Chen,&nbsp;Shengyu Hao,&nbsp;Lihua Guan ,&nbsp;Daxin Zhou","doi":"10.1016/j.ijcrp.2024.200300","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200300","url":null,"abstract":"<div><h3>Background</h3><p>Hereditary hemorrhagic telangiectasia (HHT) is an uncommon autosomal dominant condition. The combination of pregnancy and HHT can exacerbate pulmonary hypertension (PH) and, in severe cases, lead to fatality.</p></div><div><h3>Case presentation</h3><p>The case we presented is a 28-year-old multiparous woman. She developed chest tightness and dyspnea in the second trimester of pregnancy, which was not taken seriously at that time, and the symptoms worsened postpartum. Echocardiography showed elevated pulmonary artery pressure (PAP) and the computerized tomographic pulmonary angiogram revealed a significant pulmonary arteriovenous malformation. The patient's condition continued to deteriorate despite treatment to reduce pulmonary hypertension. We reviewed and updated the history of omission, recurrent epistaxis during pregnancy, and similar symptoms running in her family. Combined with the whole exon genetic testing report revealing the ACVRL1 gene mutation at chr12:52308295, the diagnosis of HHT was established. Four months later, a transcatheter closure of the pulmonary arteriovenous fistula was performed, with satisfying outcomes presenting a decrease of more than 15 mmHg in the pulmonary artery pressure. As of right now, the patient's status is stable during the outpatient follow-up.</p></div><div><h3>Conclusions</h3><p>HHT is a rare condition that typically occurs alongside abnormal communication between pulmonary veins and arteries, leading to a high-flow state in the pulmonary circulation. A pulmonary hypertension crisis can also be triggered by the patient's pregnancy, which further increases blood volume. By reducin<span>https://www.ecdc.europa.eu/sites/default/files/documents/Methods-for-the%20detection-and-characterisation-of-SARS-CoV-2-variants-first-update-WHO-20-Dec-2021.pdfg</span><svg><path></path></svg> pulmonary vascular flow, catheter closure of the pulmonary arteriovenous fistula decreases pulmonary arterial pressure.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200300"},"PeriodicalIF":1.9,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000655/pdfft?md5=46e6f964d95051afc16c35717a173066&pid=1-s2.0-S2772487524000655-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rigid ring vs. flexible band for tricuspid valve repair in patients with tricuspid valve regurgitation: A systematic review and meta-analysis","authors":"Shadi Alaa Abdelaal ,&nbsp;Mahmoud Tarek Hefnawy ,&nbsp;Enas Ewais ,&nbsp;Naydeen Mostafa ,&nbsp;Ahmed Mohamed Abozaid ,&nbsp;Adel Mouffokes ,&nbsp;Amnir Moustapha ,&nbsp;Mohamed Mohamed ,&nbsp;Hazem S. Ghaith ,&nbsp;Alaa Ramadan ,&nbsp;Nathan Ezie Kengo ,&nbsp;Ahmed Negida","doi":"10.1016/j.ijcrp.2024.200296","DOIUrl":"https://doi.org/10.1016/j.ijcrp.2024.200296","url":null,"abstract":"<div><h3>Background &amp; objectives</h3><p>Rigid ring and Flexible band are techniques used to repair tricuspid valve regurgitation. The comparison between both techniques' effectiveness is controversial in the literature. We conducted this systematic review and meta-analysis to compare the safety and efficacy of rigid ring versus flexible band for tricuspid valve repair in patients with tricuspid valve regurgitation.</p></div><div><h3>Methods</h3><p>We conducted a PRISMA-compliant systematic review and meta-analysis. A systematic search was performed in major databases, including PubMed, Scopus, Web of Science, and Cochrane CENTRAL to identify relevant published studies. Data were extracted and analyzed using Stata (version 17 for Mac) and Revman (version 5.4 for Windows).</p></div><div><h3>Results</h3><p>Twelve studies were included in this meta-analysis. Total number of patients was 4259. The rigid ring wasn't superior to the flexible band in terms of postoperative tricuspid regurgitation RR 0.74, 95 % CI (0.43–1.27) (P = 0.29). However, the results were not homogeneous. After employing sensitivity analysis, the significance of the pooled effect estimate didn't change, showing no significant difference between the two annuloplasty RR 0.72, 95%CI (0.45–1.15). On the other hand, the rigid ring was associated with a higher bypass time than the flexible band (RR 4.85, P = 0.00). There were no differences between the two groups in terms of hospital stay, ICU stays, prolonged ventilation, mechanical ventilation time, annuloplasty size, stroke, concomitant mitral valve surgery, concomitant aortic valve surgery, atrial fibrillation, pacemaker implantation, low cardiac output, in-hospital death, or late death (all P &gt; 0.05).</p></div><div><h3>Conclusion</h3><p>Our study findings suggested no difference between rigid ring compared to flexible band regarding the rates of postoperative tricuspid regurgitation; however, rigid ring may encompass a higher bypass time. Therefore, further research is required to ensure our findings.</p></div>","PeriodicalId":29726,"journal":{"name":"International Journal of Cardiology Cardiovascular Risk and Prevention","volume":"22 ","pages":"Article 200296"},"PeriodicalIF":1.9,"publicationDate":"2024-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2772487524000618/pdfft?md5=9aed2c1aa6c12e009ce3cb659e4ba50d&pid=1-s2.0-S2772487524000618-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141480886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}