Current Opinion in Colloid & Interface Science最新文献_第10页

Peptide meets membrane: Investigating peptide-lipid interactions using small-angle scattering techniques 肽与膜:使用小角度散射技术研究肽与脂质相互作用

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101709

Josefine Eilsø Nielsen , Vladimir Rosenov Koynarev , Reidar Lund

{"title":"Peptide meets membrane: Investigating peptide-lipid interactions using small-angle scattering techniques","authors":"Josefine Eilsø Nielsen , Vladimir Rosenov Koynarev , Reidar Lund","doi":"10.1016/j.cocis.2023.101709","DOIUrl":"https://doi.org/10.1016/j.cocis.2023.101709","url":null,"abstract":"<div><p>Peptide–lipid interactions play an important role in defining the mode of action of drugs and the molecular mechanism associated with many diseases. Model membranes consisting of simple lipid mixtures mimicking real cell membranes can provide insight into the structural and dynamic aspects associated with these interactions. Small-angle scattering techniques based on X-rays and neutrons (SAXS/SANS) allow <em>in situ</em> determination of peptide partition and structural changes in lipid bilayers in vesicles with relatively high resolution between 1-100 nm. With advanced instrumentation, time-resolved SANS/SAXS can be used to track equilibrium and nonequilibrium processes such as lipid transport and morphological transitions to time scales down to a millisecond. In this review, we provide an overview of recent advances in the understanding of complex peptide–lipid membrane interactions using SAXS/SANS methods and model lipid membrane unilamellar vesicles. Particular attention will be given to the data analysis, possible pitfalls, and how to extract quantitative information using these techniques.</p></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"66 ","pages":"Article 101709"},"PeriodicalIF":8.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1625519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pulmonary surfactant-derived antiviral actions at the respiratory surface 肺表面活性剂在呼吸表面的抗病毒作用

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101711

Miriam Isasi-Campillo , Paula Losada-Oliva , Jesús Pérez-Gil, Bárbara Olmeda, Lucía García-Ortega

{"title":"Pulmonary surfactant-derived antiviral actions at the respiratory surface","authors":"Miriam Isasi-Campillo , Paula Losada-Oliva , Jesús Pérez-Gil, Bárbara Olmeda, Lucía García-Ortega","doi":"10.1016/j.cocis.2023.101711","DOIUrl":"https://doi.org/10.1016/j.cocis.2023.101711","url":null,"abstract":"<div><p>Lung surfactant (LS) is a membrane-based lipid-protein complex that lines the alveoli, reducing the surface tension at the air-liquid interface and thus minimizing the work of breathing. Besides this function, LS is also the first physical barrier between the outside air and the systemic circulation, therefore playing a key role in the defense against harmful particles and microorganisms.</p><p>Viral respiratory tract infections (RTIs), and especially acute lower RTIs, are one of the leading causes of morbidity and mortality worldwide. LS participates in the network of interactions between viruses and the immune system to prevent or lessen the effects of the infection, but it is also altered by these pathogens, which can potentially impair its function.</p><p>The aim of this review is to provide an integrated multidisciplinary overview toward understanding the interplay between respiratory viruses and LS and its health impact on the respiratory system. The review is centered on the antiviral mechanisms of both LS proteins and lipids, and their different interactions that lead to varying outcomes. Finally, a summary of the clinical application of surfactant in the scene of lung viral infection is disclosed, including state-of-the-art approaches of the therapeutic use of surfactant components.</p></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"66 ","pages":"Article 101711"},"PeriodicalIF":8.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3208430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gold and silver nanoparticles as tools to combat multidrug-resistant pathogens 金和银纳米粒子作为对抗多药耐药病原体的工具

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101710

Arianna Balestri , Jacopo Cardellini , Debora Berti

{"title":"Gold and silver nanoparticles as tools to combat multidrug-resistant pathogens","authors":"Arianna Balestri , Jacopo Cardellini , Debora Berti","doi":"10.1016/j.cocis.2023.101710","DOIUrl":"https://doi.org/10.1016/j.cocis.2023.101710","url":null,"abstract":"<div><p><span>The sudden emergence and rapid spreading of viral, bacterial, and fungal infections and the usual development of resistance against traditional molecular drugs prompt the urgent need for alternative approaches to kill or inactivate pathogenic agents. This motivation has inspired a vast number of research works devoted to the design, synthesis, and application of nanomaterials, specifically inorganic plasmonic </span>nanoparticles<span>, as antimicrobial agents. We will pay special attention to articles from 2019 to 2023 where control of the colloidal properties, i.e., size, morphology, and colloidal stability, are properly considered. Here we will discuss the latest advancement in synthesis, colloidal characterization, and antimicrobial activity of Au and Ag nanoparticles, as well as hybrid systems based on combining metallic NPs with inorganic and organic materials. We will also consider contributions focusing on the green synthesis of plasmonic particles, highlighting the opportunities and the need for better control and predictivity of colloidal and functional properties.</span></p></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"66 ","pages":"Article 101710"},"PeriodicalIF":8.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3454977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Carbon nanomaterials in microbial sensing and bactericidal applications 碳纳米材料在微生物传感和杀菌中的应用

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101719

Kumar Sagar Jaiswal , Nila Nandha Kadamannil , Raz Jelinek

{"title":"Carbon nanomaterials in microbial sensing and bactericidal applications","authors":"Kumar Sagar Jaiswal , Nila Nandha Kadamannil , Raz Jelinek","doi":"10.1016/j.cocis.2023.101719","DOIUrl":"https://doi.org/10.1016/j.cocis.2023.101719","url":null,"abstract":"<div><p><span>The spread of antimicrobial resistance<span><span> and lesser development of new antibiotics have intensified the search for new antimicrobial and diagnostic vehicles. Carbon nanomaterials (CNMs), which broadly include </span>carbon dots, </span></span>carbon nanotubes<span>, and graphene/graphene oxide nanostructures, have emerged as promising theranostic materials exhibiting, in many instances, potent antibacterial activities and diagnostic capabilities. Ease of synthesis, tunable physicochemical properties, biocompatibility, and diverse modes of action make CNMs a powerful class of theranostic nanomaterials. This review discusses recent studies illuminating innovative new CNMs and their applications in bacterial theranostics. We particularly emphasize the relationship between the structural parameters and overall chemical properties of CNMs and their biological impact and utilization. Overall, the expanding work on the development and use of CNMs in therapeutic, sensing, and diagnostic applications in the microbial world underscores the considerable potential of these nanomaterials.</span></p></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"66 ","pages":"Article 101719"},"PeriodicalIF":8.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"2889773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Self-assembly of Functionalized Materials 功能化材料的自组装

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101743

Junbai Li

引用次数: 0

Engineering antimicrobial surfaces by harnessing polymeric nanoassemblies 工程抗菌表面利用高分子纳米组件

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101706

Djallal Ikkene , Olivia M. Eggenberger , Cora-Ann Schoenenberger , Cornelia G. Palivan

{"title":"Engineering antimicrobial surfaces by harnessing polymeric nanoassemblies","authors":"Djallal Ikkene , Olivia M. Eggenberger , Cora-Ann Schoenenberger , Cornelia G. Palivan","doi":"10.1016/j.cocis.2023.101706","DOIUrl":"https://doi.org/10.1016/j.cocis.2023.101706","url":null,"abstract":"<div><p>The increasing number of multidrug-resistant bacteria is a growing threat to global public health. Contaminated surfaces pose a major problem in the spreading of these superbugs and are a source of bacterial infections that are difficult to treat. Surfaces that repel bacteria or impede biofilms where bacteria are inaccessible to conventional drugs are in great demand for medical and technological applications. Immense multi-disciplinary efforts are being made to develop biocompatible, long-lasting, scalable, and cost-effective antimicrobial surfaces. Here, we highlight emerging strategies that involve harnessing natural and synthetic polymeric nanoassemblies that are antimicrobial either by themselves or through association with antimicrobial compounds to engineer antimicrobial surfaces. Our aim is to move underexplored nanoassemblies into the limelight. Based on their chemical versatility, structural tenability, and orthogonal activity of associated molecules and structures, the nanoassemblies discussed overcome cytotoxicity, non-biodegradability, and short-term antibacterial activity to offer novel surfaces with improved antibacterial and antibiofilm prospects.</p></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"66 ","pages":"Article 101706"},"PeriodicalIF":8.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"1625518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Recent advances in antimicrobial surfaces via tunable molecular interactions: Nanoarchitectonics and bioengineering applications 通过可调分子相互作用的抗菌表面的最新进展:纳米建筑学和生物工程应用

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101707

Meng Wu , Jifang Liu , Xiaogang Wang , Hongbo Zeng

引用次数: 0

Review of structural design guiding the development of lipid nanoparticles for nucleic acid delivery 核酸传递脂质纳米颗粒的结构设计综述

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101705

Marité Cárdenas , Richard A. Campbell , Marianna Yanez Arteta , M. Jayne Lawrence , Federica Sebastiani

引用次数: 2

Recent experimental advances in probing the colloidal properties of viruses 探测病毒胶体特性的最新实验进展

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101703

Antonius Armanious , Milad Radiom , Raffaele Mezzenga

{"title":"Recent experimental advances in probing the colloidal properties of viruses","authors":"Antonius Armanious , Milad Radiom , Raffaele Mezzenga","doi":"10.1016/j.cocis.2023.101703","DOIUrl":"https://doi.org/10.1016/j.cocis.2023.101703","url":null,"abstract":"<div><p>Colloidal properties of viruses largely define the stability, transport, and host interactions of viruses. Despite attempts to unravel the correlation between colloidal virus properties and their interactions outside and inside their host, an in-depth understanding is still missing. This knowledge gap is, to a great extent, caused by challenges associated with the capacity to probe these properties experimentally; thus, great efforts are being invested in developing new approaches or transforming existing ones to characterize the physical-chemical, i.e., colloidal, properties of viruses. Understanding the correlation between these properties and virus interactions is not only important from a scientific point of view but will also hopefully inspire the design of novel viral vectors and virus-like particles for biomedical applications. In this review, we cover the recent experimental advances in characterizing the colloidal properties of viruses with particular attention to virus hydrophobicity, genetic load, nanomechanical properties, and surface interaction forces with host cells.</p></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"66 ","pages":"Article 101703"},"PeriodicalIF":8.9,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"3079834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Progress in the design and synthesis of viscosupplements for articular joint lubrication 关节润滑用粘剂的设计与合成研究进展

IF 8.9 2区化学

Current Opinion in Colloid & Interface Science Pub Date : 2023-08-01 DOI: 10.1016/j.cocis.2023.101708

Gavin Gonzales , Stefan Zauscher , Shyni Varghese

引用次数: 0