{"title":"Microfluidic production of hydrogel-shelled microcapsules and their applications","authors":"Jiwoo Lee , Ji-Won Kim , Shin-Hyun Kim","doi":"10.1016/j.cocis.2025.101936","DOIUrl":"10.1016/j.cocis.2025.101936","url":null,"abstract":"<div><div>Hydrogel shells enable precise compartmentalization of aqueous cores while regulating transmembrane molecular transport based on size- and charge-selectivity. Recent advances in droplet microfluidics have enabled the production of monodisperse multiple-emulsion droplets, which serve as ideal templates for hydrogel shell fabrication. This mini-review highlights recent progress in microfluidic emulsion templating for hydrogel shell production and explores optimal design strategies for diverse applications. Hydrogel shells are fabricated using various types of emulsions, with formation mechanisms and material selection tailored to each type. Their applications span drug and cell microcarriers, microreactors, and microsensors, where the composition, structure, and crosslinking density are precisely engineered.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"78 ","pages":"Article 101936"},"PeriodicalIF":7.9,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144501651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amro K.F. Dyab , Agata N. Burska , Vesselin N. Paunov
{"title":"Aqueous two-phase emulsion systems in 3D cell culture","authors":"Amro K.F. Dyab , Agata N. Burska , Vesselin N. Paunov","doi":"10.1016/j.cocis.2025.101933","DOIUrl":"10.1016/j.cocis.2025.101933","url":null,"abstract":"<div><div>The development of realistic 3D cell culture models by using emulsions and capillary suspensions based on aqueous two-phase systems (ATPS) has advanced the areas of cell physiology and biology. It has shown the potential to enhance the fields of cancer research, biotechnology, rapid testing of drug efficiency and toxicity, tissue engineering, as well as regenerative medicine. It has been increasingly accepted that 3D cells culture more closely reflects normal cellular function due to the enhanced cell interactions, which mimic the in vitro microenvironment and architecture of natural organs and tissues. In this review, we discuss the ATPS-aided methods to form 3D cell spheroids and cell networks by using colloids as templates for the purposes of cell structuring and will discuss the limitations and the advantages of these approaches. The use of ATPS-based cell spheroids has helped to advance basic cell sciences, including understanding cancer cell interactions with their environment in solid tumors, creating better drug models and studying cancer metastasis. Such multi-cellular assemblies have also been applied for engineering tissue constructs which have great potential for studying cell interactions in biological systems under a more realistic <em>in vitro</em> environment compared to 2D cell culture.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"78 ","pages":"Article 101933"},"PeriodicalIF":7.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Micro- and nanoplastics as transport vectors for organic contaminants in the environment: A critical review","authors":"Charlotte Henkel , Thorsten Hüffer , Snežana Maletić , Thilo Hofmann","doi":"10.1016/j.cocis.2025.101934","DOIUrl":"10.1016/j.cocis.2025.101934","url":null,"abstract":"<div><div>The impact of micro- and nanosized plastic particles on the mobility of organic contaminants in the environment is a topic of ongoing scientific debate. Their extensive surface area and capacity to interact with organic contaminants have led to frequent concerns that micro- and nanoplastics significantly enhance their mobility and facilitate contaminant uptake by marine biota. For terrestrial systems, this hypothesis has been adopted, raising concerns that plastic particles could facilitate the transport of contaminants into deeper soil layers, thereby posing a threat to groundwater resources, especially in agricultural soils. These soils receive substantial plastic input through various sources, such as organic soil amendments, mulch, recycled wastewater, and atmospheric deposition. This review examines the molecular interactions between organic contaminants, including a wide range of non-intentionally added substances and additives, and plastic interfaces. We critically analyze the role of micro- and nanoplastics as vectors for contaminants in both marine environments and agricultural soils. Our analysis suggests that the vector effect of contaminants via micro- and nanoplastics in the marine environment is generally insignificant compared to other exposure routes. Our calculations regarding the mass transfer of common plastic additives indicate that the role of micro- and, particularly, nanoplastics as carriers for the majority of organic contaminants in agricultural soils is limited due to rapid desorption rates. Although micro- and nanoplastics do not considerably contribute to transport phenomena as vectors, it is crucial to recognize that they are significant sources of potentially harmful contaminants. These issues must be addressed in the forthcoming INC-5 plastic treaty.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"78 ","pages":"Article 101934"},"PeriodicalIF":7.9,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pickering emulsions stabilized by cellulose nanofibers obtained from agricultural and food waste","authors":"Noriko Kanai , Izuru Kawamura","doi":"10.1016/j.cocis.2025.101931","DOIUrl":"10.1016/j.cocis.2025.101931","url":null,"abstract":"<div><div>Cellulose nanofibers (CNFs) have been extensively studied as natural stabilizers and emulsifiers for oil-in-water Pickering emulsions (PEs). While wood has been the primary source of CNFs worldwide, agricultural and food waste (AFW) is an attractive biomass source due to its fast growth and abundance. AFW-derived CNFs share structural similarities with wood-derived CNFs, with comparable emulsifying properties, and have attracted significant attention in food and cosmetics industries. Importantly, developing PEs stabilized by AFW-derived CNFs creates new research opportunities for waste valorization and upcycling into sustainable materials. This review summarizes the latest research of PEs stabilized by AFW-derived CNFs and cellulose nanocrystals.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"78 ","pages":"Article 101931"},"PeriodicalIF":7.9,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144470156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cintia J. Fernandez, Verónica Volpe, Analía Guerrero, Danielle Silva do Nascimento, Marcos Grünhut
{"title":"Confocal Raman spectroscopy applied to microemulsions and nanoemulsions","authors":"Cintia J. Fernandez, Verónica Volpe, Analía Guerrero, Danielle Silva do Nascimento, Marcos Grünhut","doi":"10.1016/j.cocis.2025.101932","DOIUrl":"10.1016/j.cocis.2025.101932","url":null,"abstract":"<div><div>Raman spectroscopy is a light scattering technique in which a molecule scatters incident light at different wavelengths depending on the chemical structure of the analyte, from a high-intensity laser light source. The Raman scattered light is detected to create the Raman spectrum, which is unique to the chemical compounds present in the sample, acting as chemical fingerprints. Since Raman spectrometers can be coupled to a confocal microscope, the selection of regions of interest and a high magnification of the image of the sample can be achieved. Furthermore, 2D and 3D mapping can be generated from thousands of Raman spectra acquired from different positions on the sample, showing the distribution of individual chemical components in the sample. This review summarizes recent advances in the application of confocal Raman spectroscopy to the physicochemical and analytical characterization of microemulsions and nanoemulsions, focusing primarily on topical formulations and biological studies (<em>in-vitro</em> and <em>ex-vivo</em>), and including representative <em>in-vivo</em> and clinical investigations. Identification, quantification, and distribution of components (surfactants, oil phase, active ingredients, etc.) in the colloidal systems, as well as to biological studies related to dynamic processes of formulations in different tissues, even in real-time, were performed. The methodological aspects of confocal Raman spectroscopy in recent works were adequately described, discussed, and compared. Also, we analyzed the limitations and advantages of the spectroscopic technique, including its contribution to green chemistry. Finally, we discuss future perspectives considering its combination with chemometric and artificial intelligence algorithms to improve the quality of the results.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"78 ","pages":"Article 101932"},"PeriodicalIF":7.9,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144281053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shahzad Farooq , Muhammad Ijaz Ahmad , Abdullah , Usman Ali , Hui Zhang
{"title":"A review of recent trends in structuring oleogel-based emulsions for food applications","authors":"Shahzad Farooq , Muhammad Ijaz Ahmad , Abdullah , Usman Ali , Hui Zhang","doi":"10.1016/j.cocis.2025.101924","DOIUrl":"10.1016/j.cocis.2025.101924","url":null,"abstract":"<div><div>Oleogel emulsions, a hybrid system combining oleogelation and emulsification, have emerged as a groundbreaking innovation in colloidal science, providing sustainable and healthier alternatives for food formulation. In the broadest sense, oleogel emulsions can be structured by dispersing oleogels in water or vice versa, stabilized by interfacially adsorbed food-grade particles or entangled network structures that retard droplet–droplet coalescence and phase separation. This review aims to provide an up-to-date overview of various oil-structuring approaches, highlighting their properties, different types of oleogel-structured emulsions, and the stabilization mechanisms involved in the formation of oleogel emulsions. Specifically, the factors affecting the characteristics of oleogel emulsions are summarized, including oil types, oil/water ratios, oleogelators, emulsifiers, and processing parameters. Additionally, recent studies on the application of oleogel emulsions in food products are discussed. Currently, there are three main mechanisms responsible for stabilizing oleogel emulsions: Pickering particles, network stabilization, or a combination of both. The droplet size, physical stability, and rheological properties of oleogel emulsions are strongly influenced by the nature and concentration of the oleogelators used as they gel the oil phase, which helps achieve the desired thermomechanical and microstructural properties. Similarly, changes in the type of oils or oil/water ratios used directly impact the physicochemical properties of the systems. These structured emulsions have been widely used as fat substitutes in various food products such as ice cream, cakes, spreads, sausages, margarine, burgers, and peanut butters.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"78 ","pages":"Article 101924"},"PeriodicalIF":7.9,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144184872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent advances in fluorine-free functionalized nanomaterials for low-wettability applications","authors":"Donald Hill, Henry Apsey, Shirin Alexander","doi":"10.1016/j.cocis.2025.101922","DOIUrl":"10.1016/j.cocis.2025.101922","url":null,"abstract":"<div><div>The reduction in wettability afforded by applying superhydrophobic coatings onto substrate materials imbues many useful properties. This review presents recent research advancements of superhydrophobic surfaces formed from functionalised nanoparticles in some of their most promising applications. Silica and metal oxide nanoparticles can be readily functionalised with commercially available hydrophobic compounds to lower their surface energy and can be easily applied to materials with complicated forms and topographies using methods such as spraying or dipping, thus making the coating process adaptable to many situations. Advances in these coatings for imbuing icephobicity, corrosion resistance, self-cleaning, oil-in-water separation, and anti-biofouling behaviour are presented in this short review.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"78 ","pages":"Article 101922"},"PeriodicalIF":7.9,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144090645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li-Hsuan Lin , Jotam Bergfreund , Peter Fischer , Pascal Bertsch
{"title":"Plant protein adsorption at oil–water interfaces: A mapping review using alternate subphase tensiometry","authors":"Li-Hsuan Lin , Jotam Bergfreund , Peter Fischer , Pascal Bertsch","doi":"10.1016/j.cocis.2025.101920","DOIUrl":"10.1016/j.cocis.2025.101920","url":null,"abstract":"<div><div>Plant proteins are rapidly emerging as functional food ingredients as a more sustainable and ethical alternative to established animal proteins, e.g., for the interfacial stabilization of emulsions and foams. To date, there is a large knowledge gap between plant and animal proteins, and it is often difficult to predict the interfacial performance of novel plant proteins, their individual fractions, and behavior as a function of processing conditions. Here, we introduce alternate subphase tensiometry (AST) as a novel method to map literature data on interfacial tension reduction of novel protein sources. We collected, compiled, and reanalyzed interfacial tension literature data from pea, soy, chickpea, lentil, faba bean, wheat, and microalgae protein. AST allows standardized plotting of literature data in uniform graphs, providing a rapid overview of the present data and pinpointing current gaps. Furthermore, grouped data can be readily singled out to identify promising protein fractions and effects of processing conditions such as pH, ionic strength, or pretreatments. Hence, AST is a powerful tool to summarize the existing data landscape, identify research gaps and particularly promising protein fractions, and ultimately predict the interfacial performance of plant proteins for interfacial stabilization of emulsions and foams.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"77 ","pages":"Article 101920"},"PeriodicalIF":7.9,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143927683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Designing tomorrow’s polymers: Enabling multiscale porous structures from high internal phase emulsions via additive manufacturing","authors":"Nihan Sengokmen-Ozsoz , Frederik Claeyssens","doi":"10.1016/j.cocis.2025.101921","DOIUrl":"10.1016/j.cocis.2025.101921","url":null,"abstract":"<div><div>Polymerized high internal phase emulsions (polyHIPEs) have been developed in the 1980s. However, thanks to the advancements in additive manufacturing (AM), they can now be used to produce multiscale porous materials. They were first used in light-based AM setups in 2013 and in extrusion-based AM in 2016. This review aims to analyze the synergy between polyHIPEs and AM technologies and provide a perspective on the use of HIPEs as printing resins/inks. It also demonstrates the potential of polyHIPEs in next-generation applications by creating multifunctional, porous materials capable of meeting the evolving demands of various industries.</div></div>","PeriodicalId":293,"journal":{"name":"Current Opinion in Colloid & Interface Science","volume":"77 ","pages":"Article 101921"},"PeriodicalIF":7.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143934997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}