Colloids and Surfaces B: Biointerfaces最新文献_第8页

Corrigendum to "Effects of gold nanostructures on differentiation of mesenchymal stem cells" [Colloid. Surf. B: Biointerfaces 184 (2019) 110494].

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-21 DOI: 10.1016/j.colsurfb.2024.114469

Long Yuan, Xiaowei Qi, Gaoping Qin, Qi Liu, Fan Zhang, Yong Song, Jun Deng

引用次数: 0

Corrigendum to "Preparation of antibacterial hydrogel from poly(aspartic hydrazide) and quaternized N-[3-(dimethylamino) propyl] methylacrylamide copolymer with antioxidant and hemostatic effects for wound repairing" [Colloids Surf. B Biointerfaces 238 (2024) 113881].

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-20 DOI: 10.1016/j.colsurfb.2024.114463

Yu Zhang, Junling Wang, Zhe Cui, Shuai Guo, Yong Wang, Wenjuan Li, Chengyan Zhou, Mingtao Run, Jianglei Qin

引用次数: 0

pH/H₂O₂ dual-responsive macrophage-targeted chitosaccharides nanoparticles to combat intracellular bacterial infection.

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-19 DOI: 10.1016/j.colsurfb.2024.114465

Xiaomei Dai, Yu Li, Yongjie Zhang, Yuqin Zou, Siyuan Yuan, Feng Gao

{"title":"pH/H2O2 dual-responsive macrophage-targeted chitosaccharides nanoparticles to combat intracellular bacterial infection.","authors":"Xiaomei Dai, Yu Li, Yongjie Zhang, Yuqin Zou, Siyuan Yuan, Feng Gao","doi":"10.1016/j.colsurfb.2024.114465","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2024.114465","url":null,"abstract":"Antibiotic resistance combined with bacteria internalization result in recurrent infections that seriously threaten human health. To overcome these problems, a pH/H2O2 dual-responsive nanoparticle (COSBN@CFS@PS) that can target macrophages, exhibiting synergistic antibiotic and β-lactamase inhibitor activity, is reported. Chitosaccharides (COS) is covalently bound with benzenboronic acid pinacol ester and assemble with cefoxitin sodium salt (CFS) to form COSBN@CFS nanoparticles. Then, COSBN@CFS was encapsulated with phosphatidylserine (PS), which aimed to targeted uptake by macrophages. After the uptake, the pH/H2O2 dual-responsive nanoparticle could effectively inhibit β-lactamase activity by release boronic acid (β-lactamase inhibitor), and then reinforced the antibacterial activity of CFS. Meanwhile, the resultant nanoparticles could significantly inhibit the growth of CFS-resistant bacteria. Furthermore, these nanoparticles could eliminate intracellular bacteria in vivo through the synergistic activities of antibiotic and β-lactamase inhibitor. The excellent biocompatibility and outstanding bactericidal activity promise COSBN@CFS@PS have great potential for diverse intracellular bacterial infection therapy.","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114465"},"PeriodicalIF":5.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and performance analysis of multi-enzyme activity-doped nanozymes assisted by machine learning.

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-19 DOI: 10.1016/j.colsurfb.2024.114468

Fuguo Ge, Yonghui Gao, Yujie Jiang, Yijie Yu, Qiang Bai, Yun Liu, HuiBin Li, Ning Sui

{"title":"Design and performance analysis of multi-enzyme activity-doped nanozymes assisted by machine learning.","authors":"Fuguo Ge, Yonghui Gao, Yujie Jiang, Yijie Yu, Qiang Bai, Yun Liu, HuiBin Li, Ning Sui","doi":"10.1016/j.colsurfb.2024.114468","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2024.114468","url":null,"abstract":"Traditional design approaches for nanozymes typically rely on empirical methods and trial-and-error, which hampers systematic optimization of their structure and performance, thus limiting the efficiency of developing innovative nanozymes. This study leverages machine learning techniques supported by high-throughput computations to effectively design nanozymes with multi-enzyme activities and to elucidate their reaction mechanisms. Additionally, it investigates the impact of dopants on the microphysical properties of nanozymes. We constructed a machine learning prediction framework tailored for dopant nanozymes exhibiting catalytic activities like to oxidase (OXD) and peroxidase (POD). This framework was used to evaluate key catalytic performance parameters, such as formation energy, density of states (DOS), and adsorption energy, through density functional theory (DFT) calculations. Various machine learning models were employed to predict the effects of different doping element ratios on the catalytic activity and stability of nanozymes. The results indicate that the combination of machine learning with high-throughput computations significantly accelerates the design and optimization of dopant nanozymes, providing an efficient strategy to address the complexities of nanozyme design. This approach not only boosts the efficiency and capability for innovation in material design but also provides a novel theoretical analytical avenue for the development of new functional materials.","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114468"},"PeriodicalIF":5.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142890829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to 'One-pot synthesis of chlorhexidine-templated biodegradable mesoporous organosilica nanoantiseptics' [Colloid. Surf. B: Biointerfaces 187(2019)110653].

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-19 DOI: 10.1016/j.colsurfb.2024.114464

Yan He, Yue Zhang, Madi Sun, Chao Yang, Xiao Zheng, Chengxin Shi, Zhimin Chang, Zheng Wang, Jinying Chen, Shuchen Pei, Wen-Fei Dong, Dan Shao, Junjun She

引用次数: 0

Corrigendum to "Sodium alginate hydrogel containing platelet-rich plasma for wound healing" [Colloids Surf. B Biointerfaces 222 (2023) 113096].

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-18 DOI: 10.1016/j.colsurfb.2024.114462

Ting Wang, Wanwan Yi, Yu Zhang, Hang Wu, Hengwei Fan, Jiulong Zhao, Shige Wang

引用次数: 0

Platelet-mimicking nanoparticles loaded with diallyl trisulfide for Mitigating Myocardial Ischemia-Reperfusion Injury in rats.

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-17 DOI: 10.1016/j.colsurfb.2024.114460

Yihan Chen, Ling Lin, Lingling Xu, Qiaofeng Jin, Wenpei Fu, Ying Bai, Tian Huang, Tang Gao, Wenqian Wu, Chunyan Xu, Jing Wang, Li Zhang, Qing Lv, Yali Yang, Mingxing Xie, Xiaoqiu Dong

{"title":"Platelet-mimicking nanoparticles loaded with diallyl trisulfide for Mitigating Myocardial Ischemia-Reperfusion Injury in rats.","authors":"Yihan Chen, Ling Lin, Lingling Xu, Qiaofeng Jin, Wenpei Fu, Ying Bai, Tian Huang, Tang Gao, Wenqian Wu, Chunyan Xu, Jing Wang, Li Zhang, Qing Lv, Yali Yang, Mingxing Xie, Xiaoqiu Dong","doi":"10.1016/j.colsurfb.2024.114460","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2024.114460","url":null,"abstract":"Hydrogen sulfide (H2S) shows promise in treating myocardial ischemia-reperfusion injury (MIRI), but the challenge of controlled and sustained release hinders its clinical utility. In this study, we developed a platelet membrane-encapsulated mesoporous silica nanoparticle loaded with the H2S donor diallyl trisulfide (PM-MSN-DATS). PM-MSN-DATS demonstrated optimal encapsulation efficiency and drug-loading content. Comprehensive in vitro and in vivo assessments confirmed the biosafety of PM-MSN-DATS. In vitro, PM-MSN-DATS adhered to inflammation-activated endothelial cells and exhibited targeted accumulation in MIRI rat hearts. In vivo experiments revealed significant reductions in reactive oxygen species (ROS) and myocardial fibrosis area, improving cardiac function. Our findings highlight successfully creating a targeted H2S delivery system through platelet membrane-coated MSN nanoparticles. This well-designed drug delivery platform holds significant promise for advancing MIRI treatment strategies.","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114460"},"PeriodicalIF":5.4,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Iontophoresis-driven alterations in nanoparticle uptake pathway and intracellular trafficking in carcinoma skin cancer cells.

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-16 DOI: 10.1016/j.colsurfb.2024.114459

Gabriela Fávero Galvão, Raquel Petrilli, Vanessa Cristina Arfelli, Andréia Nogueira Carvalho, Yugo Araújo Martins, Roberta Ribeiro Costa Rosales, Leticia Fröhlich Archangelo, Luis Lamberti Pinto daSilva, Renata Fonseca Vianna Lopez

{"title":"Iontophoresis-driven alterations in nanoparticle uptake pathway and intracellular trafficking in carcinoma skin cancer cells.","authors":"Gabriela Fávero Galvão, Raquel Petrilli, Vanessa Cristina Arfelli, Andréia Nogueira Carvalho, Yugo Araújo Martins, Roberta Ribeiro Costa Rosales, Leticia Fröhlich Archangelo, Luis Lamberti Pinto daSilva, Renata Fonseca Vianna Lopez","doi":"10.1016/j.colsurfb.2024.114459","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2024.114459","url":null,"abstract":"Effective treatment of squamous cell carcinoma (SCC) poses challenges due to intrinsic drug resistance and limited drug penetration into tumor cells. Nanoparticle-based drug delivery systems have emerged as a promising approach to enhance therapeutic efficacy; however, they often face hurdles such as inadequate cellular uptake and rapid lysosomal degradation. This study explores the potential of iontophoresis to augment the efficacy of liposome and immunoliposome-based drug delivery systems for SCC treatment. The study assessed iontophoresis effects on SCC cell line (A431) viability, nanoparticle uptake dynamics, and intracellular distribution patterns. Specific inhibitors were employed to delineate cellular internalization pathways, while fluorescence microscopy and immunohistochemistry examined changes in EGFR expression and lysosomal activity. Results demonstrated that iontophoresis significantly increased cellular uptake of liposomes and immunoliposomes, achieving approximately 50 % uptake compared to 10 % with passive treatment. This enhancement correlated with modifications in endocytic pathways, favoring macropinocytosis and caveolin-mediated endocytosis for liposomes, and macropinocytosis and clathrin-mediated pathways for immunoliposomes. Moreover, iontophoresis induced alterations in EGFR distribution and triggered syncytium-like cellular clustering. It also attenuated lysosomal activity, thereby reducing nanoparticle degradation and prolonging intracellular retention of therapeutic agents. These findings underscore the role of iontophoresis in modulating nanoparticle internalization pathways, offering insights that could advance targeted drug delivery strategies and mitigate therapeutic resistance in SCC and other malignancies.","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114459"},"PeriodicalIF":5.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibacterial poly(ethyl methacrylate) surfaces constructed by facile amination with polyethyleneimine of different architectures.

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-16 DOI: 10.1016/j.colsurfb.2024.114458

Yu Zhao, Yunyun Xue, Chuyao Wang, Zihao Zhao, Ronglu Cui, Baoku Zhu

{"title":"Antibacterial poly(ethyl methacrylate) surfaces constructed by facile amination with polyethyleneimine of different architectures.","authors":"Yu Zhao, Yunyun Xue, Chuyao Wang, Zihao Zhao, Ronglu Cui, Baoku Zhu","doi":"10.1016/j.colsurfb.2024.114458","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2024.114458","url":null,"abstract":"Polymethacrylate and its derivatives are widely used in food industry and biomedical applications for their plasticity, biocompatibility and optical transparency. However, susceptibility to bacterial growth on their surfaces limits their applications. In this study, linear and branched polyethyleneimine (PEI) molecules were grafted onto poly(ethyl methacrylate) (PEMA) via aminolysis using a simple one-step method to enhance the antibacterial properties of PEMA films. PEI-modified PEMA films were characterized by ATR-FTIR, X-ray photoelectron spectroscopy (XPS), field emission scanning electron microscopy (FESEM) and thermal gravimetric analysis (TGA). The modified films exhibited optimal bactericidal efficiency of 98.0 % against Escherichia coli (E. coli) and over 99.9 % against Staphylococcus aureus (S. aureus). Furthermore, hydrolysis was found to contribute to anchoring PEI onto PEMA as well. Though branched PEI exhibited a higher grafting amount than the linear ones under same conditions, PEMA modified with linear PEI presented a similar or even higher antibacterial efficiency than those grafted with branched PEI. Overall, PEI-grafted PEMA films prepared with simple one-step method exhibit effective antibacterial properties and good biocompatibilities, making them promising candidates for biomedical devices and other applications.","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114458"},"PeriodicalIF":5.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142890823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitive electrochemical detection of glycated hemoglobin (HbA1c) using cobalt metal-organic framework/two-dimensional molybdenum diselenide nanocomposite-based immunosensors amplified by polyoxometalate/DNA aptamer.

IF 5.4 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2024-12-16 DOI: 10.1016/j.colsurfb.2024.114461

Siriporn Anuthum, Phakorn Papan, Arnat Pasena, Saranphong Yimklan, Chanchanok Aramrat, Padchanee Sangthong, Jaroon Jakmunee, Kontad Ounnunkad

{"title":"Sensitive electrochemical detection of glycated hemoglobin (HbA1c) using cobalt metal-organic framework/two-dimensional molybdenum diselenide nanocomposite-based immunosensors amplified by polyoxometalate/DNA aptamer.","authors":"Siriporn Anuthum, Phakorn Papan, Arnat Pasena, Saranphong Yimklan, Chanchanok Aramrat, Padchanee Sangthong, Jaroon Jakmunee, Kontad Ounnunkad","doi":"10.1016/j.colsurfb.2024.114461","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2024.114461","url":null,"abstract":"Clinical diagnosis and long-term diabetes management are advanced by monitoring glycated hemoglobin A1c (HbA1c) levels. New sensitive sandwich-like immunosensors for the diagnosis of early diabetes toward detecting HbA1c and hemoglobin (Hb) are demonstrated for the first time. DNA aptamers are used for signal amplification in the sensors for the detection of HbA1c and Hb. The immunosensors are constructed by coating with a cobalt-based metal-organic framework (Co-MOF)/two-dimensional molybdenum diselenide (2D MoSe2) composite onto a working electrode of an ItalSens screen-printed electrode (SPE) inserted into a Sensit/Smart Potentiostat affixed to a smartphone. After the immobilization of the antibodies, the detection is obtained by incubating the resultant SPEs in target solutions and then detecting the response of Keggin-type polyoxometalate (POM) bound on the DNA aptamer chains. In the selected potential window, the POM (silicotungstic acid, H4[α-SiW12O40]) used in this study exhibits the electron-transfer processes I and II ([α-SiW12O40]4-/5- and [α-SiW12O40]5-/6-, respectively) in the acidic buffer electrolyte. Our proposed device demonstrates exceptional performance in the recovery test of %HbA1c in healthy human plasma samples. The sensitivity, selectivity, and stability of this immunosensor are exceedingly outstanding, which makes it one of the potential analytical devices for diagnosing early diabetes by a %HbA1c assay.","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"248 ","pages":"114461"},"PeriodicalIF":5.4,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0