Colloids and Surfaces B: Biointerfaces最新文献_第9页

Osseointegration enhancement by controlling dispersion state of carbonate apatite in polylactic acid implant 控制碳酸磷灰石在聚乳酸植入物中的分散状态增强骨整合

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-13 DOI: 10.1016/j.colsurfb.2023.113588

Cheng Zhang, Koichiro Hayashi, Kunio Ishikawa

{"title":"Osseointegration enhancement by controlling dispersion state of carbonate apatite in polylactic acid implant","authors":"Cheng Zhang, Koichiro Hayashi, Kunio Ishikawa","doi":"10.1016/j.colsurfb.2023.113588","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2023.113588","url":null,"abstract":"<div>Osteoconductive ceramics (OCs) are often used to endow polylactic acid (PLA) with osseointegration ability. Conventionally, OC powder is dispersed in PLA. However, considering cell attachment to the implant, OCs may be more favorable when they exist in the form of aggregations, such as granules, and are larger than the cells rather than being dispersed like a powder. In this study, to clarify the effects of the dispersion state of OCs on the osseointegration ability, carbonate apatite (CAp), a bone mineral analog that is osteoconductive and bioresorbable, powder–PLA (P-PLA), and CAp granule–PLA (G-PLA) composite implants were fabricated via thermal pressing. The powder and granule sizes of CAp were approximately 1 and 300–600 µm, respectively. G-PLA exhibited a higher water wettability and released calcium and phosphate ions faster than P-PLA. When cylindrical G-PLA, P-PLA, and PLA were implanted in rabbit tibial bone defects, G-PLA promoted bone maturation compared to P-PLA and pure PLA. Furthermore, G-PLA bonded directly to the host bone, whereas P-PLA bonded across the osteoid layers. Consequently, the bone-to-implant contact of G-PLA was 1.8- and 5.6-fold higher than those of P-PLA and PLA, respectively. Furthermore, the adhesive shear strength of G-PLA was 1.9- and 3.0-fold higher than those of P-PLA and PLA, respectively. Thus, G-PLA achieved earlier and stronger osseointegration than P-PLA or PLA. The findings of this study highlight the significance of the state of dispersion of OCs in implants as a novel strategy for material development.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113588"},"PeriodicalIF":5.8,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41227699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polydopamine functionalized polyurethane shape memory sponge with controllable expansion performance triggered by near-infrared light for incompressible hemorrhage control 聚多巴胺功能化聚氨酯形状记忆海绵，具有由近红外光触发的可控膨胀性能，用于不可压缩的出血控制。

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-13 DOI: 10.1016/j.colsurfb.2023.113590

Feng Sang , Luqi Pan , Zhixiao Ji , Bingxu Zhang , Zhizhen Meng , Lina Cao , Jing Zhang , Xujian Li , Xiao Yang , Changcan Shi

{"title":"Polydopamine functionalized polyurethane shape memory sponge with controllable expansion performance triggered by near-infrared light for incompressible hemorrhage control","authors":"Feng Sang , Luqi Pan , Zhixiao Ji , Bingxu Zhang , Zhizhen Meng , Lina Cao , Jing Zhang , Xujian Li , Xiao Yang , Changcan Shi","doi":"10.1016/j.colsurfb.2023.113590","DOIUrl":"10.1016/j.colsurfb.2023.113590","url":null,"abstract":"<div>Uncontrolled expansion of shape memory sponges face a significant challenge in the treatment of lethal incompressible hemorrhage, which can lead to blood overflow or damage to the surrounding tissue. Herein, we developed a polydopamine functionalized polyurethane shape memory sponge (PDA-TPI-PU) with a controllable degree of expansion by near-infrared (NIR) light-triggered stimulation for the treatment of incompressible hemorrhage. The sponge has excellent liquid absorption performance and robust mechanical strength as well as good photothermal conversion ability. Under NIR light of 0.32 W/cm2, the maximum recovery rate of the fixed-shape compression sponge was 91% within 25 s in air and 80% within 25 s in blood. In the SD rat liver penetrating injury model, compared with commercial medical gelatin sponge and PVA sponge, the PDA-TPI-PU sponge could effectively control the bleeding under the NIR light irradiation and did not cause excessive compression of the wound. The sponge with these characteristics shows potential application prospects as a hemostatic material.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113590"},"PeriodicalIF":5.8,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49672260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of adding gelatin on the stability of water in water emulsions formed by mixtures of amylopectin and guar gum 添加明胶对支链淀粉和瓜尔胶混合物形成的水包水乳液稳定性的影响。

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-12 DOI: 10.1016/j.colsurfb.2023.113593

Jiafeng Chen , Jian Guo , Xiaoquan Yang , Taco Nicolai

{"title":"Effect of adding gelatin on the stability of water in water emulsions formed by mixtures of amylopectin and guar gum","authors":"Jiafeng Chen , Jian Guo , Xiaoquan Yang , Taco Nicolai","doi":"10.1016/j.colsurfb.2023.113593","DOIUrl":"10.1016/j.colsurfb.2023.113593","url":null,"abstract":"<div>Stable water in water (W/W) emulsions of guar rich droplets dispersed in an amylopectin rich continuous phase (G/A) and the inverse (A/G) can be achieved by adding gelatin and inducing microphase separation of the latter by cooling. In this research, the effect of gelatin on the emulsion stability was further studied by storing the emulsions at 10, 20 and 25 °C. The visual aspect, the microstructure, and the viscosity of the emulsions were investigated at different times during storage at different temperatures and pH. It was found that depending on the conditions, the gelatin phase wetted the interface or formed small discrete microdomains that adsorbed at the interface and dispersed in the bulk phases. The observed differences in morphology and stability are related to the interplay of the rates of aggregation, phase separation of gelatin, which itself depend on the gelatin concentration, temperature and pH. Emulsions could be prepared in this manner that were stable for at least one week and remained visually homogeneous. We believe that this is a promising method to stabilize W/W emulsions as long as the components of the emulsion are incompatible with aggregated gelatin.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113593"},"PeriodicalIF":5.8,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49672253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimicrobial films fabricated with myricetin nanoparticles and chitosan derivation microgels for killing pathogenic bacteria in drinking water 杨梅素纳米颗粒和壳聚糖微凝胶制备的饮用水中致病菌抗菌膜

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-12 DOI: 10.1016/j.colsurfb.2023.113591

Yu Zhu , Xu Zhang , Enze Sun , Jiang Wu , Jiaxiang Guo , Anboyuan Lv , Xiaozhou Li , Ke Wang , Lin Wang

{"title":"Antimicrobial films fabricated with myricetin nanoparticles and chitosan derivation microgels for killing pathogenic bacteria in drinking water","authors":"Yu Zhu , Xu Zhang , Enze Sun , Jiang Wu , Jiaxiang Guo , Anboyuan Lv , Xiaozhou Li , Ke Wang , Lin Wang","doi":"10.1016/j.colsurfb.2023.113591","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2023.113591","url":null,"abstract":"<div>Pathogenic bacteria in drinking water threaten human health and life. In the work, antimicrobial films composed of myricetin@tannic acid (My@TA) nanoparticles (NPs) and chitosan derivation microgels were developed to kill pathogenic bacteria in drinking water. Hydrophobic My was first made into water soluble My@TA NPs using a solvent exchange method with TA as stabilizer. Polymeric microgels of carboxymethyl chitosan (CMCS)/hydroxypropyltrimethyl ammonium chloride chitosan (HACC) were then fabricated with a blending method. CMCS&HACC/My@TA multilayer films were further deposited on the internal surface of PET bottles by using a layer-by-layer (LbL) assembly technique. The PET bottles coated with the films could effectively kill pathogenic bacteria in water such as S. aureus, E. coli, Staphylococcus epidermidis, Pseudomonas fluorescens, Listeria monocytogenes and methicillin resistant Staphylococcus aureus (MRSA). In addition, CMCS&HACC/My@TA films displayed good antioxidant activity, water resistance, and in vivo biocompatibility with heart, liver, spleen, lung and kidney organs. We believe that the container coated with CMCS&HACC/My@TA films can be applied to prevent microbial contamination of drinking water.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113591"},"PeriodicalIF":5.8,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41227697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increasing the aqueous solubility of the anesthetic propofol through wormlike micelle formation 通过形成蠕虫状胶束增加麻醉剂丙泊酚的水溶性。

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-12 DOI: 10.1016/j.colsurfb.2023.113592

Fernando B. Okasaki, Luís G.T.A. Duarte, Edvaldo Sabadini

{"title":"Increasing the aqueous solubility of the anesthetic propofol through wormlike micelle formation","authors":"Fernando B. Okasaki, Luís G.T.A. Duarte, Edvaldo Sabadini","doi":"10.1016/j.colsurfb.2023.113592","DOIUrl":"10.1016/j.colsurfb.2023.113592","url":null,"abstract":"<div>Propofol, a phenol derivative, is commonly employed as an intravenous anesthetic during clinical procedures, formulated as an oil/water emulsion due to its poor solubility in water. The stability limitations associated with emulsions have prompted research efforts towards developing aqueous formulations of propofol. In this work, we investigate the solubility enhancement of propofol in anionic and cationic surfactants. Our findings reveal that the solubility of propofol can increase significantly, up to 100-fold, depending on the nature of the micellar aggregate, as observed for alkylammonium halogenates CnTAB (for n = 12, 14 and 16), contrasting with the lower solubility with SDS. Interestingly, C14TAB and C16TAB demonstrate significantly higher solubility than C12TAB. This was attributed to the formation of wormlike micelles, in which the propofol molecules are positioned between the cationic heads of the surfactant molecules, changing the micellar curvature and the morphology of the aggregate. Therefore, the aromatic molecules in the micellar environment can be partitioned into the micellar cores and their palisades. Regarding C12TAB, the alkyl chain is too short to form wormlike micelles, thus, concentrating propofol molecules mainly into the micellar core, and consequently, leading to their aggregation. Solubility diagrams of propofol were constructed in conjunction with different surfactants. The systems exhibiting viscoelastic behavior, indicative of wormlike micelle formation, were further investigated using rheology. Additionally, the fluorescent properties of propofol enabled the examination of the anesthetic molecule within diverse micellar environments.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113592"},"PeriodicalIF":5.8,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49672256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fe-Ni dual-single atoms nanozyme with high peroxidase-like activity for sensitive colorimetric and fluorometric dual-mode detection of cholesterol 具有高过氧化物酶样活性的Fe-Ni双单原子纳米酶用于胆固醇的灵敏比色和荧光双模式检测。

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-12 DOI: 10.1016/j.colsurfb.2023.113589

Jia-Qi Li, Yan-Wen Mao, Rui Zhang, Ai-Jun Wang, Jiu-Ju Feng

{"title":"Fe-Ni dual-single atoms nanozyme with high peroxidase-like activity for sensitive colorimetric and fluorometric dual-mode detection of cholesterol","authors":"Jia-Qi Li, Yan-Wen Mao, Rui Zhang, Ai-Jun Wang, Jiu-Ju Feng","doi":"10.1016/j.colsurfb.2023.113589","DOIUrl":"10.1016/j.colsurfb.2023.113589","url":null,"abstract":"<div>Cholesterol is widely existed in nerve myelin sheath and various membrane structures, whose abnormal level would deteriorate human cells or even cause diseases. Herein, Fe-Ni dual-single-atom nanozyme was efficiently incorporated into N-doped carbon nanosheets (FeNi DSAs/N-CSs) by a simple calcination method. Its nanozyme activity and catalytic mechanism were investigated in details. The FeNi DSAs/N-CSs nanozyme showed superior peroxidase-like property, which was applied for the dual-mode determination of hydrogen peroxide (H2O2) and cholesterol. The colorimetric/fluorometric assays of H2O2 displayed the linear ranges of 1–50 mM and 5–40 mM with low limits of detection of 0.45 mM and 3.33 mM, respectively. In parallel, there exhibited the linear ranges of 0.5–5.0 mM and 0.25–5.0 mM for the colorimetric/fluorometric analysis of cholesterol, coupled with the limits of detection down to 0.19 mM and 0.044 mM, respectively. This work provided a rapid, cost-effectiveness and simple colorimetric/fluorometric method for sensitive dual-mode detection of cholesterol in human serum samples.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113589"},"PeriodicalIF":5.8,"publicationDate":"2023-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49672255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A biomimetic in situ mineralization ECM composite scaffold to promote endogenous bone regeneration 仿生原位矿化ECM复合支架促进内源性骨再生

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-11 DOI: 10.1016/j.colsurfb.2023.113587

Lin Tang , Xiaoying Chen , Mei Wang , Yuhua Liu , Bowen Li , Yuke Li , Yi Zhang

{"title":"A biomimetic in situ mineralization ECM composite scaffold to promote endogenous bone regeneration","authors":"Lin Tang , Xiaoying Chen , Mei Wang , Yuhua Liu , Bowen Li , Yuke Li , Yi Zhang","doi":"10.1016/j.colsurfb.2023.113587","DOIUrl":"https://doi.org/10.1016/j.colsurfb.2023.113587","url":null,"abstract":"<div>Bone tissue engineering scaffolds constructed from single-component organic materials have inherent limitations. Inspired by the hierarchical structure of physiological natural bone hard tissues, our research explores the construction of organic-inorganic composite scaffold for bone regeneration. In this study, we used a natural and readily obtainable extracellular matrix (ECM) material, i.e., decellularized small intestinal submucosa (SIS), to build the organic component of a phosphorylated hydroxyapatite nanocrystal-containing composite scaffold (nHA@SIS). Guided by polymer-induced liquid-precursor theory, we introduced a soluble inorganic mineralization solution to achieve an inorganic component of nHA@SIS. Using in situ mineralization, we successfully formed inorganic component within SIS and constructed nHA@SIS composite scaffold. We analyzed the physicochemical properties and the osteogenic role of nHA@SIS via a series of in vitro and in vivo studies. Compared with SIS scaffold, the nHA@SIS possessed suitable physicochemical properties, maintained the excellent cell activity of SIS and better guided reorganization of the cell skeleton, thereby achieving superior osteoconductivity and maintaining osteoinductivity at the protein and gene levels. Furthermore, the rat cranial defect area in the nHA@SIS scaffold group was mostly repaired after 12 weeks of implantation, with a larger amount of higher-density new bone tissue being visible at the edge and center than SIS and blank control group. This significantly improved in vivo osteogenic ability indicated the great potential of nHA@SIS for bone tissue engineering applications.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113587"},"PeriodicalIF":5.8,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41227696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Siliplant1 B-domain precipitates silica spheres, aggregates, or gel, depending on Si-precursor to peptide ratios Siliplant1B-结构域沉淀二氧化硅球体、聚集体或凝胶，这取决于Si前体与肽的比例。

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-07 DOI: 10.1016/j.colsurfb.2023.113582

Vincent Otieno Ayieko , Lilian Cohen , Sabrina Diehn , Gil Goobes , Rivka Elbaum

{"title":"Siliplant1 B-domain precipitates silica spheres, aggregates, or gel, depending on Si-precursor to peptide ratios","authors":"Vincent Otieno Ayieko , Lilian Cohen , Sabrina Diehn , Gil Goobes , Rivka Elbaum","doi":"10.1016/j.colsurfb.2023.113582","DOIUrl":"10.1016/j.colsurfb.2023.113582","url":null,"abstract":"<div>Silica is extensively deposited by plants, however, only little is known about the molecular control over this process. Siliplant1 is the only known plant protein to precipitate biosilica. The protein contains seven repeats made of three domains. One of the domains exhibits a conserved sequence, which catalyzes silica precipitation in vitro. Here, silica was synthesized by the activity of a peptide carrying this conserved sequence. Infrared spectroscopy and thermal gravimetric analyses showed that the peptide was bound to the mineral. Scanning electron microscopy showed that silica-peptide particles of 22 ± 4 nm aggregated to spherical structures of 200–300 nm when the ratio of silicic acid to the peptide was below 183:1 molecules. When the ratio was about 183:1, similar particles aggregated into irregular structures, and silica gel formed at higher ratios. Solid-state NMR spectra indicated that the irregular aggregates were richer in Si-O-Si bonds as well as disordered peptide. Our results suggest that the peptide catalyzed the condensation of silicic acid and the formation of ∼20 nm particles, which aggregated into spheres. Excess of the peptide stabilized surface Si-OH groups that prevented spontaneous Si-O-Si bonding between aggregates. Under Si concentrations relevant to plant sap, the peptide and possibly Siliplant1, could catalyze nucleation of silica particles that aggregate into spherical aggregates.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113582"},"PeriodicalIF":5.8,"publicationDate":"2023-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49672261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Injectable glucose oxidase-immobilized gelatin hydrogel prevents tumor recurrence via oxidation therapy 可注射葡萄糖氧化酶固定明胶水凝胶通过氧化疗法预防肿瘤复发。

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-06 DOI: 10.1016/j.colsurfb.2023.113581

Changkyu Lee

引用次数: 0

Plasmonic inhibition of bacterial adhesion on gold-decorated mesoporous zirconium oxide thin films 等离子体抑制细菌在金修饰的介孔氧化锆薄膜上的粘附。

IF 5.8 2区医学

Colloids and Surfaces B: Biointerfaces Pub Date : 2023-10-02 DOI: 10.1016/j.colsurfb.2023.113576

M. Florencia Tebele, Gastón Paris, Andrés Zelcer

{"title":"Plasmonic inhibition of bacterial adhesion on gold-decorated mesoporous zirconium oxide thin films","authors":"M. Florencia Tebele, Gastón Paris, Andrés Zelcer","doi":"10.1016/j.colsurfb.2023.113576","DOIUrl":"10.1016/j.colsurfb.2023.113576","url":null,"abstract":"<div>Preventing bacterial development on surfaces is essential to avoid problems caused by biofouling. Surfaces decorated with gold nanoparticles have been shown to thermally kill bacteria under high-intensity NIR illumination. In this study, we evaluated the colonization by E. coli of nanostructured surfaces composed of mesoporous zirconia thin films, both with and without gold nanoparticles embedded into the pores. We studied the effect of the nanostructure and of low intensity visible light excitation of the gold nanoparticles on the colonization process. We found that neither the zirconia, nor the presence of pores, or even gold nanoparticles affect bacterial adhesion compared to the bare glass substrate. Therefore, mesoporous zirconia thin films are biologically inert scaffolds that enable the construction of robust surfaces containing functional nanoparticles that can affect bacterial growth. When the gold containing surfaces are irradiated with light, bacterial adhesion shows a remarkable 96 ± 4% reduction. Our studies revealed that these surfaces affect early colonization steps, prior to biofilm formation, preventing bacterial adhesion without affecting its viability. In contrast to related systems where plasmonic excitation induces membrane damage due to strong local heating, the membrane integrity is preserved, showing that these surfaces have a different working principle.</div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"232 ","pages":"Article 113576"},"PeriodicalIF":5.8,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49672259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0