Colloids and Surfaces B: Biointerfaces最新文献

{"title":"Hyaluronic acid-based strategies for prostate cancer therapy","authors":"Xueling Lan ,&nbsp;Qunhua Zhou ,&nbsp;Haitong Wang ,&nbsp;Zhongyi Mu ,&nbsp;Liyang Pan ,&nbsp;Liqun Yang ,&nbsp;Qiang Du","doi":"10.1016/j.colsurfb.2026.115448","DOIUrl":"10.1016/j.colsurfb.2026.115448","url":null,"abstract":"<div><div>Hyaluronic acid (HA) has emerged as a pivotal biomaterial in prostate cancer management, bridging the gap between physical tissue spacing and targeted molecular therapy. While HA-based hydrogels are clinically established, and nanomedicines are rapidly evolving, a comprehensive integration of these distinct domains remains lacking. This review critically synthesizes the dual roles of HA in prostate cancer radiotherapy and drug delivery. We first delineate the biological basis of HA, emphasizing its interactions with CD44/RHAMM receptors and the implications for material design. Clinically, we systematically evaluate the efficacy of HA hydrogel spacers across diverse radiotherapy modalities, including SBRT, brachytherapy, and hypofractionated regimens, highlighting their quantitative impact on prostate-rectum separation and the substantial reduction of gastrointestinal toxicity. Beyond physical spacing, we analyze the translational status of HA-based nanocarriers, discussing their potential to overcome drug resistance through receptor-mediated active targeting. Crucially, we address significant limitations in current strategies, such as the structural heterogeneity arising from imprecise chemical modifications and the lack of standardized in vivo stability evaluation systems. Finally, we propose a roadmap for future research, advocating for subtype-specific material design, the development of intelligent stimuli-responsive derivatives, and synergy with emerging immunotherapies to realize precision medicine in prostate cancer.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115448"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145974862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temperature-responsive hydrogel delivery of antimicrobial peptide engineered watermelon-derived extracellular vesicles enables sequential infection control and wound healing","authors":"Ziyang Bai ,&nbsp;Yifan Zhao ,&nbsp;Yajuan Gong ,&nbsp;Meijun Du ,&nbsp;Wenjun Zhang ,&nbsp;Ke Zhang ,&nbsp;Yongchao Zhi ,&nbsp;Yanan Nie ,&nbsp;Xia Li ,&nbsp;Xiuping Wu ,&nbsp;Bing Li","doi":"10.1016/j.colsurfb.2026.115438","DOIUrl":"10.1016/j.colsurfb.2026.115438","url":null,"abstract":"<div><div>Infected wounds present major clinical challenges due to excessive bacterial colonization, sustained inflammation, and impaired tissue repair. To address these barriers, we developed a temperature-responsive hydrogel delivery system incorporating watermelon-derived extracellular vesicles (wEV), antimicrobial peptide-engineered for the topical treatment of infected wounds. wEVs contained terpenoids, flavonoids, alkaloids, and proteins with intrinsic anti-inflammatory and pro-regenerative activity. To enhance stability and antibacterial potency, antimicrobial peptides (AMP) were conjugated to wEVs via mussel derivatives, producing wEV-AMP. These were embedded in a temperature-responsive Pluronic F127/chitosan hydrogel that gels at 37 °C for wound coverage and controlled release. <em>In vitro</em>, PF127/CS+wEV-AMP inhibited &gt; 95 % of <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>, suppressed biofilms, reduced inflammatory cytokines, and enhanced fibroblast migration. In infected rat wounds, healing rate reached ∼60 % by day 5 and nearly complete closure by day 14, with greater collagen deposition and M2 macrophage polarization. This multifunctional hydrogel integrates antimicrobial, immunomodulatory, and regenerative effects, offering strong potential for infectious wound treatment.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115438"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lysosome-targeted ROS-responsive graphene oxide-based drug delivery system to overcome tumor DOX resistance","authors":"Fengzhu Yang ,&nbsp;Jintao Deng ,&nbsp;Xinyu Yu ,&nbsp;Wenhao Fu ,&nbsp;Wenlong Sun ,&nbsp;Zhengbao Xu ,&nbsp;Xinhua Song ,&nbsp;Chao Wang ,&nbsp;Qingqing Du ,&nbsp;Meng Wang","doi":"10.1016/j.colsurfb.2026.115434","DOIUrl":"10.1016/j.colsurfb.2026.115434","url":null,"abstract":"<div><div>The lysosomes of drug-resistant tumor cells transport doxorubicin (DOX) and its nanocarriers into lysosomes through a sequestration mechanism, making it difficult for DOX to reach the therapeutic concentration. In this study, a nanodrug delivery system (Dp/DGPP) capable of overcoming tumor lysosomal resistance was developed. The system consists of three parts: graphene oxide (GO)-Se-Se-DOX, polyethyleneimine-pluronic F127 (PEI-PF127) for improved biocompatibility, and Dp44mT for amplifying reactive oxygen species (ROS) and disrupting lysosomes. After entering MCF-7/ADR tumor cells, loading Dp44mT can reduce the permeability of lysosomal membranes by increasing the level of ROS. DOX subsequently escapes from lysosomes and breaks the diselenide bond to complete its release. The experiment proved that Dp/DGPP exhibited a significant ROS-dependent response to the release of DOX. Compared with the other groups, it had greater cytotoxicity, and the IC50 value of DOX against MCF-7/ADR cells was as low as 6.71 μM. Compared with the DOX group, the Dp/DGPP group exhibited greater DOX accumulation in MCF-7/ADR cells, with 1.5-fold greater fluorescence at 4 h. Meanwhile, Dp/DGPP can cause lysosomal dysfunction by reducing lysosomal membrane permeability. Western blot results revealed that the expression of Pgp protein decreased in the Dp/DGPP group, whereas the expression of autophagy related LC3-II and P62 protein increased, which confirmed that autophagic flux was blocked. This reduces potential drug resistance and promotes cell death. In addition, the Dp/DGPP group achieved a 70 % inhibition rate in MCF-7/ADR tumors in vivo. This nanodrug delivery system provides a potential strategy to overcome tumor DOX resistance via lysosomes.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115434"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, characterization, and in vitro evaluation of Eudragit-coated aminated mesoporous silica nanoparticles loaded with pterostilbene for colon delivery","authors":"Nikhil Raut ,&nbsp;Manasa N. ,&nbsp;Swornahuti Panda,&nbsp;Victor Hmingthangsanga,&nbsp;Subramanian Natesan","doi":"10.1016/j.colsurfb.2026.115452","DOIUrl":"10.1016/j.colsurfb.2026.115452","url":null,"abstract":"<div><div>Ulcerative colitis (UC), a chronic inflammatory colon disease, often requires long-term care. Pterostilbene (PTB), a naturally occurring substance with strong anti-inflammatory and antioxidant properties, has shown therapeutic potential; however, its poor aqueous solubility and instability at stomach pH limit its clinical application. A colon-targeted drug delivery system loaded with PTB and coated with Eudragit S100 (EU) was developed using mesoporous silica nanoparticles (MSN). The MSN were surface-aminated using 3-aminopropyl triethoxysilane (APTES) to obtain aminated mesoporous silica nanoparticles (AMSN), which provided pH-responsive release and enhanced drug binding. FT-IR spectroscopy confirmed the encapsulation of the drug and amine functionalization through characteristic spectral shifts. X-ray diffraction (XRD) showed decreased crystallinity of PTB, suggesting effective molecular dispersion within the MSN matrix. Differential scanning calorimetry (DSC) was used to confirm the amorphous form of the encapsulated medication. Morphological study using SEM and TEM revealed consistently spherical, porous nanoparticles. Thermogravimetric analysis (TGA) demonstrated the formulation's thermal stability, and Brunauer-Emmett-Teller (BET) analysis showed high surface area and pore volume, both of which are advantageous for efficient drug loading. In vitro release investigations confirmed a pH-dependent, extended release of the drug under intestinal conditions. Additionally, pro-inflammatory cytokines (TNF-α and IL-6) were significantly reduced in the ELISA assays of LPS-stimulated HT-29 cells, demonstrating the formulation's anti-inflammatory efficacy. The development of colon-specific delivery of pterostilbene, the Eudragit-coated PTB-loaded AMSN (Eu-PTB-AMSN), effectively addresses the primary shortcomings of conventional PTB formulations, including low solubility, stomach instability, and systemic adverse effects, while offering a practical therapeutic approach for the treatment of UC.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115452"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145974860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surface-enhanced Raman scattering (SERS) in antibiotic resistance detection: Advances, challenges, and future perspectives","authors":"Biqing Chen ,&nbsp;Jiayin Gao ,&nbsp;Haizhu Sun ,&nbsp;Yan Liu ,&nbsp;Yinghan Zhao ,&nbsp;Xiaohong Qiu ,&nbsp;Yang Li","doi":"10.1016/j.colsurfb.2026.115423","DOIUrl":"10.1016/j.colsurfb.2026.115423","url":null,"abstract":"<div><div>Antimicrobial resistance (AMR) has emerged as one of the most critical global public health crises, causing an estimated 700,000 deaths annually according to the World Health Organization. Achieving early, rapid, and accurate detection and identification of drug-resistant bacteria is essential to addressing this challenge. Surface-enhanced Raman scattering (SERS), a highly sensitive, label-free, and non-invasive optical detection technology, has demonstrated great potential in bacterial identification and antimicrobial resistance analysis. In recent years, the integration of SERS with artificial intelligence (AI) technologies particularly machine learning (ML) and deep learning (DL) methods has enabled unprecedented accuracy and efficiency in resistance detection. This review systematically summarizes recent advances in SERS–AI combined strategies for AMR detection, analyzes the strengths and limitations of various approaches, and explores their potential applications in clinical and surveillance settings. Finally, the importance of continuous technological innovation and interdisciplinary collaboration in this field is emphasized to promote the translational application of SERS–AI strategies in the global fight against AMR.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115423"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteoinductive sandwich-structured HA/PEEK implant for rapid critical-size skull repair","authors":"Mei-li Qi ,&nbsp;Kunshan Yuan ,&nbsp;Enhui Song ,&nbsp;Xiangyi Feng ,&nbsp;Tianheng Lu ,&nbsp;Lin Zhao ,&nbsp;Haihong Guo ,&nbsp;Haijun Zhang","doi":"10.1016/j.colsurfb.2026.115428","DOIUrl":"10.1016/j.colsurfb.2026.115428","url":null,"abstract":"<div><div>Critical-size bone defects afflict millions annually, driving a cascade of inflammation and incomplete tissue regeneration. Polyetheretherketone (PEEK) remains the material of choice for load-bearing implants because its modulus mirrors that of cortical bone; yet its notorious bioinertness curtails both anti-inflammatory signaling and osseointegration, stalling the healing process. To break this stalemate, we designed a sandwich-structured, osteoinductive hydroxyapatite (HA)/PEEK implant tailored for skull repair. A porous PEEK core was engineered via the salting out technique and its surface was homogeneously functionalized with HA through simple physical blending, preserving the implant’s open porosity while imparting potent osteoinductive activity. In a rabbit critical calvarial defect (10 mm diameter), new bone advanced from the periphery to the center, achieving full osseous continuity within only 4 months and markedly surpassing unmodified PEEK. The robust bone-implant integration demonstrated by this sandwich HA/PEEK construct not only converts a bioinert polymer into an osteoinductive implant but also may expand treatment options for growing children, offering a clinically translatable solution for skull repair after trauma, hemorrhage, tumor resection, or congenital dysplasia.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115428"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145915403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combining lactate oxidase and metformin in cancer cell membrane-biomimetic liposomes for synergistic ferroptosis induction and hypoxia-alleviated cancer therapy","authors":"Cheng-Lei Li ,&nbsp;Feng-Ming Li ,&nbsp;Ke-Ke Feng ,&nbsp;Yong-Shan Hu ,&nbsp;Yi-Fan Tu ,&nbsp;Shi-Cheng Tian ,&nbsp;Zhen-Hua Liu ,&nbsp;Jing-Wei Shao","doi":"10.1016/j.colsurfb.2026.115420","DOIUrl":"10.1016/j.colsurfb.2026.115420","url":null,"abstract":"<div><div>Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxide accumulation, offers a promising strategy to circumvent tumor drug resistance. However, solid tumors exhibit intrinsic resistance to ferroptosis due to elevated antioxidant systems and hypoxic microenvironments, limiting H₂O₂-mediated lipid peroxidation. Herein, we developed a tumor-homing liposomal platform (ML-MLip) for co-delivery of lactate oxidase (LOX) and metformin (MET) to leverage the tumor microenvironment for enhanced ferroptosis induction. LOX catalyzes intratumoral abundant lactate (due to the Warburg effect) to generate H₂O₂, while MET alleviates tumor hypoxia by inhibiting mitochondrial complex I, ensuring sufficient oxygen for LOX activity. Concurrently, MET suppresses SLC7A11-mediated GSH synthesis and disabling GPX4-mediated lipid peroxide detoxification. Soybean phosphatidylcholine (SPC) within ML-MLip provides polyunsaturated lipids as substrates for peroxidation, overcoming endogenous lipid shortages. <em>In vitro</em> and <em>in vivo</em> studies demonstrated that ML-MLip preferentially accumulated at tumor sites, triggering iron-dependent lipid peroxidation (LPO) and ferroptosis. Additionally, lactate depletion and ferroptosis reversed the tumor immunosuppressive microenvironment, promoting the release of tumor antigens and damage-associated molecular patterns (DAMPs) to augment systemic immune responses. This strategy converts tumor-specific metabolites (lactate) and ions (iron) into therapeutic effectors, offering a microenvironment-responsive approach for synergistic ferroptosis-immunotherapy against malignant tumors.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115420"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incorporating Mn²⁺ ions in bioactive sol-gel coatings: Impact on cell adhesion, inflammation and bone regeneration","authors":"C. Arias-Mainer ,&nbsp;F. Romero-Gavilán ,&nbsp;L. Abenia-Artigas ,&nbsp;I. García-Arnáez ,&nbsp;O. Amorrotu ,&nbsp;M. Azkargorta ,&nbsp;F. Elortza ,&nbsp;M. Gurruchaga ,&nbsp;I. Goñi ,&nbsp;J. Suay","doi":"10.1016/j.colsurfb.2026.115436","DOIUrl":"10.1016/j.colsurfb.2026.115436","url":null,"abstract":"<div><div>Manganese (Mn), an essential trace element involved in bone metabolism, plays a crucial role in key biological functions, including the regulation of cell adhesion, modulation of immune responses, and promotion of osteogenesis. In this study, sol-gel coatings with increasing concentrations of MnCl₂ (0.5, 1 and 1.5 % wt) were synthesised and applied onto titanium (Ti) surfaces. The materials were characterised physicochemically, and <em>in vitro</em> responses were assessed using human osteoblasts (HOb) and THP-1-derived macrophages. Protein adsorption from human serum was analysed by nLC-MS/MS. The incorporation of MnCl₂ did not disrupt the sol-gel silica network and enabled a sustained release of Mn²⁺ ions, and all coatings showed good biocompatibility with no cytotoxicity. Immune response analysis revealed that 0.5Mn promoted anti-inflammatory markers (IL-10, TGF-β), while 1Mn and 1.5Mn induced strong proinflammatory profiles, reflected in increased TNF-α and IL-1β. Proteomics identified preferential adsorption of immune-related proteins such as complement components, ficolins, acute-phase proteins and apolipoproteins to 1Mn and 1.5Mn. Conversely, 0.5Mn enhanced the adsorption of proteins linked to anti-inflammatory effects and oxidative stress regulation. Mn-doped surfaces also enhanced gene expression related to cell adhesion (CTNNB1, ITG1B, PTK2) and osteogenic markers (RUNX2, BMP2, BGLAP), particularly on 1.5Mn, correlating with increased calcium deposition and adsorption of mineralisation-related proteins (FETUA, ECM1, IGF2). All Mn sol-gel coatings promoted the coagulation cascade through increased adsorption of FA9, FA12 and ZPI. These results demonstrate the capacity of Mn-doped sol-gel coatings to modulate immune and osteogenic responses, underscoring the relevance of optimising Mn concentration to improve bone–implant integration.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115436"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145964831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Luteolin-loaded nanocomposites target microglia for sepsis-associated encephalopathy therapy via intranasal delivery","authors":"Weihong Guo ,&nbsp;Tao Liu ,&nbsp;Xiaojia Peng ,&nbsp;Jiafa Zhang ,&nbsp;Zhefeng Chen ,&nbsp;Chongshuang Xia ,&nbsp;Canhong Yang ,&nbsp;Shuting Xie ,&nbsp;Tianming Lü","doi":"10.1016/j.colsurfb.2026.115433","DOIUrl":"10.1016/j.colsurfb.2026.115433","url":null,"abstract":"<div><div>Sepsis-associated encephalopathy (SAE) is a neurological dysfunction resulting from sepsis, with neuroinflammation identified as a key pathogenic mechanism. Luteolin (LUT) is a dietary polyphenol that possesses considerable therapeutic potential. However, its application is hindered by poor aqueous solubility, low absorption, and rapid metabolism. To address these challenges, we developed luteolin-loaded lactoferrin-chondroitin sulfate nanoparticles (LUT-LF-CS NPs) to enhance the bioavailability of LUT and evaluate its efficacy in alleviating neuroinflammation in SAE. The optimized LUT-LF-CS NPs exhibited a uniform particle size of 45.9 nm and an encapsulation efficiency of 71.73 %. These nanocomposites demonstrated excellent cytocompatibility and enhanced the intrinsic antioxidant and anti-inflammatory activities of LUT. Furthermore, they facilitated cellular uptake in microglia through CD44 receptor-mediated endocytosis, enabling effective drug delivery to the cerebral cortex after intranasal administration. Mechanistically, LUT-LF-CS NPs promoted the polarization of microglia from the pro-inflammatory M1 phenotype to the anti-inflammatory M2 phenotype while inhibiting the TLR4/MyD88/NF-κB signaling pathway. In conclusion, LUT-LF-CS NPs significantly enhance the neuroprotective effects of LUT, positioning them as a promising therapeutic strategy for SAE.</div></div>","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115433"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Biomimetic oral drug delivery: Translating nature’s design into therapeutic innovation” [Colloids Surf. B: Biointerfaces 259 (2026) 115348]","authors":"Muzaffaruddin Ahmed Madny ,&nbsp;Khushwant S. Yadav","doi":"10.1016/j.colsurfb.2026.115502","DOIUrl":"10.1016/j.colsurfb.2026.115502","url":null,"abstract":"","PeriodicalId":279,"journal":{"name":"Colloids and Surfaces B: Biointerfaces","volume":"261 ","pages":"Article 115502"},"PeriodicalIF":5.6,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146111801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}