Chemosphere最新文献

{"title":"Beyond the watchlist: How the TOP assay exposes untargeted PFASs for current and future regulations in consumer products","authors":"Christophe Bleuler ,&nbsp;Tania Bernardez ,&nbsp;Vanessa Inderbitzin ,&nbsp;Andreas M. Buser ,&nbsp;Harold Bouchex-Bellomie ,&nbsp;Philippe Favreau","doi":"10.1016/j.chemosphere.2026.144841","DOIUrl":"10.1016/j.chemosphere.2026.144841","url":null,"abstract":"<div><div>Due to human exposure and environmental risks, per- and polyfluoroalkyl substances (PFASs) in commercial products are subject to increasingly stringent and worldwide regulations. In this study, impregnation products (<em>n</em> = 25), textiles (<em>n</em> = 15) and food contact materials (<em>n</em> = 18), mainly from the Swiss market, were selected for their water- or grease-proof capabilities and assessed for the presence of PFASs. Total fluorine was detected in 52 % of impregnation products, 87 % of textiles, and 61 % of food contact materials by combustion ion chromatography. A targeted analysis of perfluoroalkyl carboxylic acids (PFCAs), sulfonic acids (PFSAs), and fluorotelomer sulfonates (FTSs) resulted in individual PFASs concentrations that were all below 165 ppb. The application of a modified total oxydizable precursor (TOP) assay to the samples enabled the transformation of oxidizable precursors, including side-chain fluorinated polymers, into PFCAs, with average increases in concentrations of the targeted PFASs in fluorine equivalents by a factor of 23 600 for impregnation products, 1300 for textiles, and 420 for food contact materials. The PFCA fingerprints were dominated by short C₆ chains, which are currently being restricted by national and international regulations. In this context, applying the TOP assay uncovered a significant proportion of samples with precursors providing perfluorohexanoic acid (PFHxA) concentrations above the 1000 ppb threshold, compared to a direct PFASs targeted approach. While providing a snapshot of the current market situation, this study demonstrates the usefulness of a TOP assay for enforcing regulatory compliance. It also highlights the prevalence of short-chain PFASs in commercial products despite the availability of fluorine-free alternatives.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"396 ","pages":"Article 144841"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146101185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of a 2D hydrodynamic model (IBER) to quantify pollutant loads in the Lerma River: A case study in the Toluca-north industrial corridor","authors":"Luis Jesús Osornio Berthet,&nbsp;Magdalena García Martínez,&nbsp;Oscar Cruz Castro,&nbsp;Jorge Meléndez Estrada","doi":"10.1016/j.chemosphere.2026.144862","DOIUrl":"10.1016/j.chemosphere.2026.144862","url":null,"abstract":"<div><div>The impact of human activities on a watershed can be modeled through various approaches and tools, such as hydrological simulation models and water quality models. These models can help predict how deforestation, illegal discharges from polluting industries, urbanization, mining, and other human activities will affect water quantity and quality in the watershed. The present project seeks to analyze the impacts of human activities in the Upper Lerma River Basin in the Toluca Valley. This area has been severely affected by excessive demographic growth and the marked presence of industries. The main objective of this project is to identify the main sources of contamination in the area and evaluate their impact on the environment, proposing mitigation and prevention measures. To carry out this study, water sampling was carried out at different strategic points in the basin. The results obtained were analyzed to identify the main contaminants present and evaluate their impact on water quality, the health of the population, and the biodiversity of the area. In addition, through the use of geoportals such as watershed simulators and Geographic Information Systems (GIS), the polluting routes of the industries present in the area were analyzed to determine their degree of responsibility for the environmental problems. In summary, this project seeks to contribute to the conservation and restoration of the ecosystem of the Upper Lerma River Basin in the Toluca Valley by identifying the sources of contamination, evaluating their impact, and proposing sustainable solutions to guarantee sustainable development in the area.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"397 ","pages":"Article 144862"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmentally relevant levels of BDE-209 induces proteomic and phosphoproteomic reprogramming in murine melanoma cells","authors":"Mariana Galvão Ferrarini ,&nbsp;Micheli Marchi ,&nbsp;Erick Laurent Moggio ,&nbsp;Hulyana Brum ,&nbsp;Fernanda G. Kugeratski ,&nbsp;Michel Batista ,&nbsp;Ciro Alberto Oliveira Ribeiro ,&nbsp;Andréa Rodrigues Ávila","doi":"10.1016/j.chemosphere.2026.144857","DOIUrl":"10.1016/j.chemosphere.2026.144857","url":null,"abstract":"<div><div>Polybrominated diphenyl ethers (PBDEs), notably decabromodiphenyl ether (BDE-209), are persistent organic pollutants widely used as flame retardants and frequently detected in electronic waste. Despite global restrictions, BDE-209 remains an environmental contaminant with bioaccumulative and potentially risk to human health. This study investigated the proteomic and phosphoproteomic effects of chronic concentration BDE-209 exposure in murine melanoma (B16–F1) cells, aiming to elucidate molecular mechanisms underlying pollutant-induced phenotypic changes of malignancy. Cells were exposed to environmentally relevant concentrations of BDE-209 (0.1 and 1 nM) for 15 days, selected based on levels previously reported in human biological samples and on prior <em>in vitro</em> and <em>in vivo</em> studies investigating chronic low-concentration exposure, followed by mass spectrometry-based analyses. A total of 3369 proteins and 4422 phosphosites were identified. BDE-209 exposure resulted in distinct proteomic signatures, including the exclusive expression in exposed cells of proteins such as PRKDC, and modulation of pathways involved in DNA repair, mRNA processing, and chromatin remodeling. PRKDC is a key kinase in DNA damage repair, and it has been associated with chemotherapy resistance and poor prognosis in several cancers, suggesting its potential as a prognostic biomarker in BDE-209-related tumor progression. Additionally, proteins involved in chromatin remodeling, SUMOylation, mRNA processing, and oncogenic signaling (e.g., YES1, DIMT1, UBE2V2) were induced. Phosphoproteomic analysis revealed differential phosphorylation of proteins linked to cancer progression, including TCOF1, IRF2BP2, and HDGFRP2. These findings demonstrate that even low-dose exposure to BDE-209 can modulate cellular signaling and promote malignancy-associated phenotypic changes, underscoring its potential role in worsening cancer prognosis and highlighting the broader health risks posed by persistent environmental contaminants.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"397 ","pages":"Article 144857"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146260453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemometric modelling for eco-toxicological risk assessment of diverse chemicals towards mammalian species","authors":"Rajeshwari Das,&nbsp;Prodipta Bhattacharyya,&nbsp;Shubha Das,&nbsp;Probir Kumar Ojha","doi":"10.1016/j.chemosphere.2026.144877","DOIUrl":"10.1016/j.chemosphere.2026.144877","url":null,"abstract":"<div><div>The extensive use of chemicals in daily life can cause environmental pollution, raising global concerns about the health and safety of mammals and other species in the food chain. Many chemicals, including pesticides, pharmaceuticals, etc., can get inside the body of an organism via inhalation, ingestion, or dermal contact, causing toxic effects and potentially leading to the death of species. This research aims to assess the toxicity of diverse chemicals toward mammalian species, considering the endpoint as median lethal dose (LD₅₀). A partial least squares (PLS)-based quantitative read-across structure-activity relationship (q-RASAR) model was established by merging the structural and physicochemical properties of quantitative structure-activity relationship (QSAR) with the read-across (RA)'s similarity and error-based measures. An ARKA-RASAR approach was additionally applied to assess the model performance. Despite of stronger internal validation of ARKA-RASAR model, the PLS-based q-RASAR model was selected as the final model because of its improved external predictivity (Q²_F1 = 0.616-0.690; Q²_F2 = 0.616-0.689, MAE_test = 0.331-0.303) along with its lower complexity and ease of interpretation. For possible toxic substances identification, the q-RASAR model was also utilized to screen the Pesticides Properties DataBase (PPDB) and ECOTOX repository, ensuring the practical application of the developed model. The model revealed specific fragments like the polar surface area, electronegativity, molecular complexity, and lipophilicity, all of which are responsible for the enhancement of mammalian toxicity. This aids in the development of eco-friendly chemicals and bridging data gaps, thus bypassing traditional toxicity assessment methods.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"397 ","pages":"Article 144877"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147286669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A recent overview of photo electro catalytic materials mechanistic insights towards PFASs degradation: By-products determination and AI/ML implications","authors":"Yaswanth K. Penke ,&nbsp;Pankaj Chamoli ,&nbsp;Huang-Mu Lo","doi":"10.1016/j.chemosphere.2026.144852","DOIUrl":"10.1016/j.chemosphere.2026.144852","url":null,"abstract":"<div><div>Around 10000 compounds of Poly-and perfluoroalkyl substances (PFASs) exposure is ill-affecting the environmental resources (Direct healthcare expenditures ∼ USD 100 billion). This review details electrochemical and photo-catalytic activities of various materials/composites towards PFASs degradation. The technical observations in the current work are majorly referenced from recent literature published in the last five years (2020–2025). The iron and titanium species have shown better remediation abilities which reported with majority of publications. Iron systems have shown better parameters for electrochemical activities (electro oxidation/reduction) whereas titanium sub oxides and bismuth sheets are better related to the photo electrochemical activity. Other 3d-metal systems like Co, Ni, and boron doped diamond, carbon structures (activated carbon, carbon sphere and aerogel) are also detailed with PFOA and PFOS treatment. In understanding the degradation mechanism, the radical species activity has densely dominated the process with the support of radical oxygen/sulphur species and charge transfers. Radical species activity, dissolved oxygen influence, and direct electron transfer (DET) mechanism are provided in understanding the heterogeneous catalytic reactions and redox materials chemistry. Decarboxylation (DHEH), and hydro-defluorination (HDF) mechanisms are explained with a set of findings based on catalyst and chain length of compound (Long/Short-chain). Determination of degradation byproducts and intermediates utilizing different state-of-the-art spectroscopy tools (LC-MS, GC-MS) are detailed in supporting the issue related to the secondary contamination in various remediation sites and necessary field studies findings (e.g., Landfills, WWTP). Implications of AI/ML towards efficient handling of the various PFASs treatment and management technologies are discussed briefly.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"397 ","pages":"Article 144852"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of mercury accumulation and risk for Pacific blue mussels (Mytilus trossulus) sampled along a gradient of glacial coverage","authors":"Benjamin D. Barst ,&nbsp;Jordan Jenckes ,&nbsp;Kyle A. Capistrant-Fossa ,&nbsp;Katrin Iken ,&nbsp;Drew Porter ,&nbsp;Michelle Trifari ,&nbsp;Erin J. Ussery ,&nbsp;Kristin Nielsen","doi":"10.1016/j.chemosphere.2026.144868","DOIUrl":"10.1016/j.chemosphere.2026.144868","url":null,"abstract":"<div><div>Climate change is causing rapid glacial retreat, which may affect the concentrations of trace elements in glacial outflow entering marine environments. Mercury is a trace element of interest because it bioaccumulates and poses risks to animal and human health. Although past studies have documented elevated concentrations of mercury in glacial outflow in Alaska and other regions of the world, studies assessing the fate of glacially derived mercury are lacking. We sampled Pacific blue mussels from 10 watersheds spanning a gradient of glacial influence in two regions of coastal Alaska (Kachemak Bay and Lynn Canal). We analyzed total mercury concentrations in mussel samples and investigated the factors driving these concentrations. Our results demonstrate that total mercury concentrations are tightly correlated with glacial watershed coverage in the Kachemak Bay region, but not the Lynn Canal region where some water quality parameters were more important determinants of mussel total mercury. Glacial scouring of bedrock is an important source of particulate-bound mercury in both regions, however the homogenous bedrock geology across the Kachemak Bay study area may have allowed us to better isolate the influence of glacial coverage on mussel total mercury compared to the Lynn Canal study area, where more heterogeneous bedrock likely introduces greater variability in mercury levels among proglacial streams. The proportion of Kachemak Bay mussels with mercury concentrations above the Alaska average increased with glacial coverage, though the mussel mercury concentrations from all sites do not pose risks for human or animal consumers.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"397 ","pages":"Article 144868"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147319194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Unraveling the composition and succession of the microbial community in aerobic granular sludge treating urban wastewater with high load from hospital effluent” [Chemosphere 381 (2025) 144483]","authors":"Aurora Rosa-Masegosa ,&nbsp;Ramiro Vilchez-Vargas ,&nbsp;Susanna Gorrasi ,&nbsp;Antonio Monteoliva-García ,&nbsp;Alejandro Gonzalez-Martinez ,&nbsp;Jesus Gonzalez-Lopez ,&nbsp;Barbara Muñoz-Palazon","doi":"10.1016/j.chemosphere.2026.144866","DOIUrl":"10.1016/j.chemosphere.2026.144866","url":null,"abstract":"","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"397 ","pages":"Article 144866"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mutagenesis of PM2.5 water-bioavailable fraction in reference area for atmospheric pollution","authors":"Cristiane Silva da Silva ,&nbsp;Vera Maria Ferrão Vargas","doi":"10.1016/j.chemosphere.2026.144848","DOIUrl":"10.1016/j.chemosphere.2026.144848","url":null,"abstract":"<div><div>Airborne particulate matter (PM) is a pollutant composed of organic and inorganic suspended compounds. Fine inhalable particles (PM2.5) are associated with adverse effects on human health. Organic compounds are most evaluated for genotoxicity, however inorganics adsorbed to PM2.5 can also generate these effects. The study aimed to evaluate whether the fraction of water-soluble inorganic compounds intensifies the mutagenic response compared to those already observed in organic extracts analyzed in an area of reference for air pollution in southern Brazil. Air filters were submitted to aqueous extraction to evaluate PM2.5 inorganic compounds, especially metals, in the water-soluble fraction (WSF). Chemical analysis was performed to quantify metals. Mutagenicity was evaluated using the <em>Salmonella</em>/microsome assay (microsuspension) with strains TA97a, TA98 and TA102, in the presence and absence of rat liver metabolization fraction (±S9). Al, Zn and Cu were found in the largest quantity in the samples, although not indicating elevated mutagenic activity. Most mutagenesis results were positive for the strains and conditions tested, and TA102 was the most sensitive. Comparing the results of mutagenesis among organic (observed in previously studies) and inorganic extract samples for TA98(±S9), the highest responses were detected in the WSF extracts. Therefore, positive responses of WSF elevated the mutagenicity found for the organic fraction of PM2.5, evidencing a sum total of effect as against the different strains tested. According to results the area is no longer a reference for airborne pollution by PM2.5.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"396 ","pages":"Article 144848"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Swimming impairment caused by pharmaceuticals in native and invasive fishes: A comparison of fluoxetine effects in two poeciliid species","authors":"Martina Kolesnik ,&nbsp;Ismael Lozano ,&nbsp;Juan S. Guidobono ,&nbsp;Fabiana L. Lo Nostro ,&nbsp;Fernando J. Meijide","doi":"10.1016/j.chemosphere.2026.144860","DOIUrl":"10.1016/j.chemosphere.2026.144860","url":null,"abstract":"<div><div>Chemical pollution and invasive alien species are currently recognized as two of the major drivers of global biodiversity loss. These two pressures rarely act in isolation, but instead frequently co-occur and interact in human-modified ecosystems. The antidepressant fluoxetine (FLX) is among the neuroactive pharmaceuticals most regularly detected in watersheds worldwide, raising concerns over its potential adverse effects on the behavior of fishes and other aquatic organisms. For native fish species inhabiting FLX-polluted environments, the ability to withstand the ecological pressure from invasive species might be compromised if they prove more vulnerable to chemical pollution than their non-native counterparts. Here, we examined whether FLX impairs swimming performance at lower concentrations in the native ten-spotted livebearer <em>Cnesterodon decemmaculatus</em> than in the invasive mosquitofish <em>Gambusia holbrooki</em>. Fishes were exposed to waterborne FLX for 14 days, under semi-static conditions with daily renewal of test solutions. Following exposure, swimming activity of individual fish was video-recorded and analyzed. We found that fish exposed to 25 μg/L FLX exhibited impaired swimming behaviour, slowing down their movement and remaining for longer time static and close to the surface. Contrarily, exposure to 0.5 μg/L FLX–an environmentally relevant concentration–did not affect swimming performance in either species. Interestingly, exposure to 5 μg/L FLX, which is close to the concentration of combined antidepressants reported in surface waters, had a significant effect on overall locomotion in <em>C. decemmaculatus</em> but not in <em>G. holbrooki</em>. This finding points to a higher susceptibility of the native species as compared to the invasive one, potentially diminishing its capacity to cope with interference competition under aquatic pollution by neuroactive contaminants.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"396 ","pages":"Article 144860"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-occurrence of ionophore polyether antibiotics and pesticides in peri-urban horticultural streams: multi-matrix monitoring, partitioning, and risk assessment","authors":"M. Navarro ,&nbsp;T.M. Mac Loughlin ,&nbsp;L.L. Alonso ,&nbsp;M. Ramos ,&nbsp;K. Miglioranza ,&nbsp;C. Apartin","doi":"10.1016/j.chemosphere.2026.144861","DOIUrl":"10.1016/j.chemosphere.2026.144861","url":null,"abstract":"<div><div>Intensive horticulture and the reuse of poultry litter (PL) can introduce mixtures of pesticides and veterinary pharmaceuticals into adjacent waters. A multi-matrix study was conducted at eight stream sites in the Cinturón Hortícola Platense (Argentina) across three sampling campaigns. Surface water, suspended particulate matter (SPM), bottom sediments, and aquatic macrophytes were analyzed by LC-MS/MS. Target compounds included ionophore polyether antibiotics (IPAs), selected pesticides, avermectins and the fluoroquinolone enrofloxacin. Monensin was the most frequently detected IPA. Glyphosate and its metabolite AMPA were ubiquitous across matrices, while chlorpyrifos and its metabolite TCP were widespread in water and sediments. Prometryn and tebuconazole were consistently observed across campaigns, whereas avermectins and enrofloxacin were not detected. Macrophytes accumulated several target compounds, supporting their role as integrators of contamination. Pseudo-partition coefficients (water-sediment, water-SPM) indicated a preferential association of monensin, glyphosate, and AMPA with solid phases. Principal component analysis linked monensin with organic-matter and nutrient proxies, consistent with PL-driven runoff. A screening environmental risk assessment indicated very high risk for chlorpyrifos in water and sediment, and low risk for IPAs at observed levels. Findings highlight the complex contamination arising from horticultural practices that combine animal-derived soil amendments with pesticide applications. Sampling strategies should include transformation products and macrophyte biomonitoring, as aquatic plants can indicate agricultural contamination. The results provide actionable evidence to guide monitoring and mitigation efforts in peri-urban horticulture, emphasizing the importance of vegetated buffers, improved PL handling, and comprehensive surveillance that includes metabolites.</div></div>","PeriodicalId":276,"journal":{"name":"Chemosphere","volume":"396 ","pages":"Article 144861"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146168517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}