{"title":"CIRCULATORY CYTOKINES AND HEMATOLOGICAL PROFILES: POSSIBLE BIOMARKERS OF HIV/AIDS DISEASE PROGRESSION","authors":"J. Mugwe, M. Gicheru, J. Mwatha","doi":"10.20319/LIJHLS.2019.51.105118","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.51.105118","url":null,"abstract":"Introduction: This study sought to identify circulatory cytokines and hematological profiles measureable in blood plasma in newly diagnosed HIV patients as possible biomarkers that could predict the progression of HIV and AIDS disease in the course of acute HIV infection. Methodology: A prospective cross sectional study design was used to recruit the participants at the Nakuru Provincial General hospital in Kenya. The study group included those who were HIV positive before and after commencing therapy and those who were HIV negative. The study group composed of male and female of different ages ranging from 7-72 years. Hematology auto analyzer system was used to analyze hematological parameters and indices. Types and concentrations of cytokines were determined using multiplex cytokine immunoassay by flow cytometry using Becton and Dickinsonfluorescence activated cell sorter (BD FACS) count. Descriptive statistics were applied and a p- value < 0.05 was considered statistically significant. Results: This study found a significant difference in mean Interleukin 12p70 (p<0.001), Tumor Necrosis Factor (p<0.05), Interleukin 10 (p<0.05), Interleukin 6 (p<0.005) and interleukin 1β (p<0.05) between HIV negative patients, treatment naive HIV patients and HIV patients on highly active antiretroviral therapy (HAART). Among the treatment naive HIV patients, significant associations were observed between IL-12p70 and HGB (p<0.05); between TNF and MPV (p<0.001); between IL-10 and PDW (p<0.005); between IL-6 and Gran# (p-0.05); between IL-1β and PDW (p<0.005). Conclusion: The early period of infection with HIV is characterized by high circulatory cytokines levels and could be useful biomarkers and indicators of early immune activation of HIV infection. The results from this study also showed that acute HIV infection induces several hematological changes, involving all the blood parameters and indices, some of which may act as indicators of HIV/AIDS disease progression. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.51.105118 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123710489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DESIGN OF REMOTE CONTROLLED HEART MONITORING SYSTEM","authors":"Engin Esme, Faruk Ünsaçar","doi":"10.20319/LIJHLS.2019.51.89104","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.51.89104","url":null,"abstract":"The biological signal generated by the pulse is taken to the PC environment by means of an electrode, a preamplifier and a data acquisition (DAQ) card. An image is presented on the graphical display applying signal processing methods on the electrocardiogram (ECG) signals obtained on the PC. It has an easy-to-use interface supported by graphics on both the patient side and the specialist side. The ECG data is sent to the long-distance terminal via the GSM modem. The biggest advantage of using a GSM modem is to ensure that the specialist is independent of the place. Thus, the specialist can contact the patient at any time and at any place. The specialist analyzing ECG data can remotely manage the defibrillator device, if needed. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.51.89104 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121563911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seda Karaçay Yikar, S. Doğan, Şeyma Yurtseven, Sevban Arslan, Evşen Nazik
{"title":"AN ASSESSMENT OF MARITAL ADJUSTMENT AND SEXUAL FUNCTIONS OF WOMEN WORKING IN SHIFTS IN HEALTHCARE","authors":"Seda Karaçay Yikar, S. Doğan, Şeyma Yurtseven, Sevban Arslan, Evşen Nazik","doi":"10.20319/LIJHLS.2019.51.7388","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.51.7388","url":null,"abstract":"The aim of the study was to assess the marital adjustment and sexual functions of women working in shifts in healthcare. The population of this descriptive, cross-sectional study consisted of 152 women working in shifts in a hospital in the city of Adana. The sample of the study consisted of 117 women who met the inclusion criteria (married, active sexual life, not be in menopause, to have no premorbid psychiatric diagnosis) and who agreed to participate in the study. The data of the study was gathered using a “Personal Information Form” which included the descriptive data of the women, a “Sexual Function Index” to assess women’s sexual dysfunctions, and a “Marital Adjustment Test” to assess marital compatibilities of the women. The mean MAT score of women working in shifts in healthcare was 39,32 ± 11,01, suggesting that women had low marital adjustment. A weak positive and significant relationship was found between sexual functions and marital adjustments of women working in shifts in healthcare (r = 0.382, p < 0.05). Decreasing working hours and workloads women working in shifts, therefore allowing women to have a more active role at home, and allowing them to improve their marital relationships is suggested. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.51.7388 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123909948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Ethica, E. Semiarti, T. Raharjo, O. Oedjijono, A. R. Sulistyaningtyas, S. Darmawati
{"title":"SCREENING OF RESTRICTION ENZYMES FOR THE DEVELOPMENT OF RESTRICTION FRAGMENT-BASED, GENOMIC BIOMARKER OF ALCALIGENES JAVAENSIS","authors":"S. Ethica, E. Semiarti, T. Raharjo, O. Oedjijono, A. R. Sulistyaningtyas, S. Darmawati","doi":"10.20319/LIJHLS.2019.51.6272","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.51.6272","url":null,"abstract":"Alcaligenes javaensis is a food-borne, Gram-negative bacterium, which has the closest relationship with Alcaligenes faecalis commonly causing contamination of clinical equipment and infection on humans. Hence, the development of a biomarker for members of genus Alcaligenes including A.javaensis is needed for early detection of this bacterium. This research aimed to screen the performance of 5 restriction enzymes consisting of EcoRV, Hind III, NotI, SalI, and BgIII as singles and in combinations to produce specific pattern of restricted, genomic DNA fragments of A.javaensis. Total DNA was first extracted from subcultured A.javaensis cells using DNA isolation kit and the obtained DNA isolate was then subjected to enzyme restrictions in vitro. Later, the restricted DNA fragments were evaluated using agarose gel electrophoresis method. Results showed that only the EcoRV-BgIII-HindIII combination within a restriction process of 18 h could produce smaller-sized DNA bands, while those from other combinations (5 enzymes as singles and their 2-combinations) could not do so. As conclucion, the combination of EcoRV-BgIII-HindIII is the most potential among the evaluated endonucleases to be used as a genomic biomarker for A.javaensis. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.51.6272 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130180158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"INVESTIGATION OF THE PANDEMIC PREPAREDNESS EDUCATION OF CRITICAL CARE NURSES","authors":"Thamer Alduraywish, S. West, J. Currie","doi":"10.20319/LIJHLS.2019.51.4061","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.51.4061","url":null,"abstract":"Critical care nurses play important roles in the secondary level management and prevention of communicable disease during a pandemic. These roles include leading the pandemic response, efficiently managing limited resources, instituting infection control, and providing safe and effective care. Nurses face many challenges in adequately performing their roles given the complexity of a pandemic. Therefore, nurses must possess the relevant skills and knowledge to competently execute their tasks. This study aims to identify the research evidence underpinning the knowledge and skills required for critical care nurses to respond to a pandemic as described. An Integrative review (IR) was used and employing studies that used different research designs. As a result, a total of 33 studies were identified; qualitative (n = 17), quantitative (n = 11), and mixed-method studies (n= 5) were retrieved for the review. Emerging themes include staff attitudes and ethics, organisation, planning, and education. In conclusion critical care nurses need specialised pandemic response education to meet the challenges of managing and preventing disease outbreaks. Hospital planners and educators will benefit from improving institutional pandemic plans to build staff capacity through education and training. However, there is still a need for developing evidence-based curriculum for nursing pandemic preparedness. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.51.4061 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115769333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dinda Asa Ayukhaliza, Ananda Ayu Dhelia Ghani Damanik, S. Aisyah, Z. Ismah
{"title":"ASSOCIATION FACTORS OF DERMATITIS IN THE COASTAL AREAS","authors":"Dinda Asa Ayukhaliza, Ananda Ayu Dhelia Ghani Damanik, S. Aisyah, Z. Ismah","doi":"10.20319/LIJHLS.2019.51.0118","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.51.0118","url":null,"abstract":"Dermatitis is a skin disease that affects the quality of life, appearance and comfort of the sufferer. Dermatitis is related to various factors and causes such as infection, consumption of drugs and food, psychosomatic, and exposure to chemicals. The research method used is systematic review with a total sample of 152,996 samples. Risk factors for dermatitis in coastal areas include genetics, type of food, personal hygiene, duration of contact, disease history, years of work, personal protective equipment use, occupational history, protein contact, insect paederus, allergic history, exclusive breastfeeding status, age, education, administration of formula milk, infection and inflammation. The most studied factors are personal hygiene, history of illness and years of work. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.51.0118 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126361238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ANTIOXIDANT ACTIVITY, MOSQUITOCIDAL ACTIVITY, ANTIBACTERIAL ACTIVITY OF SOLVENT EXTRACT AND SYNTHESIZED NANOPARTICLES OF CLAUSENA EXCAVATA (BURM.) F. (RUTACEAE) AGAINST SELECTED MOSQUITOES AND PATHOGENIC BACTERIA","authors":"Yazhini Jagadeesan, E. Kuppusamy","doi":"10.20319/LIJHLS.2019.51.1939","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.51.1939","url":null,"abstract":"In the present investigation, Clausena excavata an indegeous plant was sequentially extracted with hexane, ethyl acetate and methanol and their bio efficacy in terms of Antioxidant activity, mosquitocidal activity and antibacterial activity was tested. Among the three-extract methanol extract of C. excavata displayed significant antioxidant, larvicidal, ovicidal, pupicidal activities against Aedes aegypti and Culex quinquefasciatus. Similarly, methanol extract also showed pronounced antibacterial activity against the selected human pathogenic bacteria. Thus, the methanol extract of C. excavata was used to synthesize silver mediated nanoparticles and its (C. excavata AgNPs) bio efficacy was also tested with the selected vector mosquitoes and selected human pathogenic bacteria. This present investigation envisages the possible utilization of C. excavata as a potent candidate as green pesticides in the near future. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.51.1939 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116809814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PREMENSTRUAL SYNDROME FREQUENCY, PREMENSTRUAL SYNDROME COPING STRATEGIES AND FACTORS AFFECTING PREMENSTRUAL SYNDROME IN UNIVERSITY STUDENTS IN TURKEY","authors":"Tuğba Özmermer, Fatma Koruk","doi":"10.20319/LIJHLS.2019.43.138155","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.43.138155","url":null,"abstract":"Premenstrual syndrome (PMS) symptoms influence women’s lives to a large extent. This study was conducted to understand the frequency of PMS, coping strategies and factors affecting PMS in university students in Sanliurfa, Turkey. In this cross-sectional study in which 376 university students were reached. 52.1% of the students were found to experience PMS. Engaging in various activities to expend energy eating sweets and using analgesics were found to be the most common methods used by the students to cope with PMS symptoms; however, they were not able to cope efficiently with water retention, balance/control issues and autonomic reactions. The logistic regression analysis showed that a unit of increase in age led PMS risk to increase by a factor of 1.179, whereas a unit of increase in weight led to an increase in PMS risk by a factor of 1.025. Also, low income increased PMS risk by a factor of 1.884, fast food consumption increased it by a factor of 2.069, high salt consumption by a factor of 1.884, and anemia presence by a factor of 1.739. In conclusion, the prevalence of PMS was found to be high in the students and they were observed to have difficulty in coping with certain symptoms. On the basis of the results of the study, it is recommended that university students be given information about factors affecting PMS, how to cope with symptoms, what treatments are available, and that they been couraged to receive treatment for PMS. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.43.138155 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134472876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A REALITY IN A DEVELOPING COUNTRY- BENIN: DIAGNOSIS OF CANCER WITH THE ACTIVATION OF AUTOMATED IMMUNOHISTOCHEMISTRY","authors":"T. Zanin","doi":"10.20319/LIJHLS.2019.43.128137","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.43.128137","url":null,"abstract":"Background: In the Benin-West state of Africa, cancer is one of the most frequent causes of death. For this reason from September 2015 at Saint John of God Hospital in Tanguieta – Benin – a Histopathology Laboratoy is active with the aim to make diagnosis and address towards adequate therapeutic programs patients affected from cancer and other diseases. The Laboratory has been equipped with a tele pathology system (Cross SS, Dennis T, Start RD. 2002 and Della Mea V. & Beltrami CA. 2000) and from 2018 with an Automatic System for Immunochemistry. Objectives, methods and outcomes: In the last 20 years, in collaboration with the association APOF (Pathologists across the border), diagnostic laboratories have been developed in various African countries: Tanzania - Uganda - Djibouti, etc. Immunohistochemistry has been introduced in these laboratories to formulate a correct and complete diagnosis. In Benin we had a technological breakthrough by introducing an automated immunohistochemistry system. The funds were obtained from the FAI (International Assistance Foundation) of Lugano (Switzerland) and from the UTA – Onlus. The use of validated protocols, the contribution of international experts through telepathology, the training of technical personnel on site, allowed the formulation of correct diagnoses. Conclusion: The development of complete histopathological diagnostic services of automated ICHs, such as that of Benin, is of fundamental importance for the fight against cancer in developing countries. Cancer is fought with research but also with a correct diagnosis. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.43.128137 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122585449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GENOTOXICITY OF CERIUM OXIDE NANOPARTICLE IN ZEBRAFISH AND GREEN MUSSEL PERNA VIRIDIS USING ALKALINE COMET ASSAY","authors":"J. Bhagat","doi":"10.20319/LIJHLS.2019.43.118127","DOIUrl":"https://doi.org/10.20319/LIJHLS.2019.43.118127","url":null,"abstract":"Cerium oxide nanoparticles or nanoceria has versatile application in biomedical, solar cells and gas sensors. Increasing utilization of nanoceria has raised concerns over its release to environment and potential exposure. In vitro studies have shown its genotoxic potential, but reports on aquatic life are very limited. In this study, zebrafish (Danio rerio) and green mussel (Perna viridis) was exposed to different concentration 10, 20, 50 µg/l of nanoceria for 24, 72, and 120 h and the genotoxic response was measured using comet assay. The results showed significant (p < 0.05) increase in tail DNA (TDNA) and olive tail moment (OTM) as measured using comet assay in exposed animals as compared to control. The highest TDNA and OTM were measured after 120 h of exposure with 50 µg/l of nanoceria in zebrafish as well as in green mussel. The results of this study demonstrate that short-term exposure to nanoceria causes a genotoxic response in zebrafish and green mussel, hence its environmental release should be carefully monitored. Article DOI: https://dx.doi.org/10.20319/lijhls.2019.43.118127 This work is licensed under the Creative Commons Attribution-Non-commercial 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.","PeriodicalId":260489,"journal":{"name":"LIFE: International Journal of Health and Life-Sciences","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131990753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}