Current Functional Foods最新文献

{"title":"Coloured Cereals: Nutritional Benefits And Therapeutic Properties","authors":"Sukhminderjit Kaur, N. Rani, Tanya Mishra, Babita Thakur, Rajinder Kaur","doi":"10.2174/2666862901666230726164551","DOIUrl":"https://doi.org/10.2174/2666862901666230726164551","url":null,"abstract":"\u0000\u0000Worldwide, cereals are staple foods and are needed for proper growth and development of humans. In the food industry, coloured cereals have gained popularity as potential nutraceuticals. These are high in phytochemicals, which are crucial in protecting the body from allergies, cancer, diabetes, and cardiovascular disease. Due to their strong antioxidant effects, phenolic compounds have sparked a lot of interest in many scientific fields. Anthocyanins have the potential of functional food ingredient. Anthocyanins are the ubiquitous family of natural pigments which are found in large quantities in various cereals such as corn, wheat, barley, rice, sorghum and its varieties and various colored cereals like black, red, and pink cereals. Cereals contain phenolic compounds which are found in either bound or Free State, which is called the total phenolic compound content. The present review provides health benefits properties of various photochemical of cereals, including phenolics, flavonoids, anthocyanin, proanthocyanidins, tocopherols and phytates.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115090913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacognostical, Phytochemical, and Pharmacological Aspects of Aegle marmelos: An Update","authors":"M. Kulshreshtha, Karan Agrawal, D. Pathak","doi":"10.2174/2666862901666230601145034","DOIUrl":"https://doi.org/10.2174/2666862901666230601145034","url":null,"abstract":"\u0000\u0000Due to its therapeutic characteristics, the Rutaceae family plant Aegle marmelos is one of the most important plants. The bilwa is used to treat a range of illnesses. The existence of this plant dates back to the age of the dinosaurs. The plant has a wide range of pharmacological properties, including the ability to heal wounds, act as an antipyretic, prevent diarrhoea, treat ulcers and constipation, exhibit radioprotective action, exert anti-arthritis activity, anti-thyroid activity, immunomodulatory activity, anti-fungal activity, anti-microbial activity, antioxidant activity, analgesic action, and cytoprotective action. The goal of this review is to summarise the molecular and scientific knowledge available regarding Aegle marmelos, including its phytochemical properties, pharmacological potential, and pharmacognostic traits. Data are acquired using Google, PubMed, Scholar, and other online sources.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121797555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-Inflammatory phytochemicals for the treatment of diabetic nephropathy","authors":"Aswar Urmila, Momin Armash, Shukla Pavan, Nikambe Rachana, R. Patil","doi":"10.2174/2666862901666230601100713","DOIUrl":"https://doi.org/10.2174/2666862901666230601100713","url":null,"abstract":"Diabetes is a metabolic disease characterized by hyperglycemia. Persistent hyperglycemia can cause Diabetic nephropathy (DN). It is a major microvascular complication that leads to chronic kidney disease (CKD) that progressively develops into end-stage renal disease (ESRD). It is the most debilitating condition that affects 15-25% of patients with type I diabetes and approximately 30-40% with type II diabetes worldwide.\u0000\u0000\u0000\u0000In this review, we aim at various inflammatory mediators and different inflammatory pathways involved in the progression of DN with special emphasis on phytoconstituents which gives protection against DN by acting on these mediators and pathways.\u0000\u0000\u0000\u0000The literature was searched using the following keywords: inflammation, anti-inflamatory, phytoconstitutents/ phytochemicals, diabetic nephropathy, clinical, and preclinical studies.\u0000\u0000\u0000\u0000The various epidemiological, preclinical, and clinical evidence showed a close relationship between inflammatory response and progression of DN, as such, there is no effective treatment for DN, therefore, there is an unmet need for novel therapeutic approaches to treat them. From ancient times, phytochemicals, also known as phytonutrients, are the bioactive nutrients found in plants and foods, which have proven potentially useful for human well-being. Phytochemicals have demonstrated a promising therapeutic role in nephropathy, principally through the regulation of oxidative stress and inflammation.","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125235396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Critical Review of Phytochemical, Pharmacological and Ethnomedicinal Properties of Eryngium foetidum L","authors":"Sabyasachi Banerjee, S. Bose, A. Dutta, Raja Majunder, U. Chakraborty, P. Chakraborty","doi":"10.2174/2666862901666230512102932","DOIUrl":"https://doi.org/10.2174/2666862901666230512102932","url":null,"abstract":"\u0000\u0000Eryngium foetidum L. is a biennial herb widely used in most tropical regions as a herb, and in India, its use is essentially increasing as an aromatic spice and flavouring agent. The plant is widely populated by Turkey, Southeast Asia, the Caribbean, Thailand, China, and others. This herb is becoming more popular due to its traditional uses for various ailments.\u0000Reviews have been included in peer-reviewed publications until 2020, published in English. 55 papers conveying E. foetidum-related conformation were screened, with 30 articles proven relevant and requiring authentication knowledge to build up this analysis paper. The information about 64 phytoconstituents is responsible for treating diseases like analgesia and inflammation, hyperlipidaemia, tuberculosis, coagulation, tumours, malaria, leishmaniasis, oxidation, etc. All specific knowledge must be gathered in one location, which will also assist scientists in finding and emphasising the elements of the upcoming corner in order to assess the importance of the plant being studied or to demonstrate its medicinal value.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132394363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Tea (Camellia sinensis) Extract is Effective Against Biofilms of Staphylococcus aureus and Pseudomonas aeruginosa, and Interferes on the Activity of Antimicrobial Drugs","authors":"Marcus Vinícius Dias Dias-Souza, Gustavo José da Costa, Renan Martins dos Santos, Isabela Penna Ceravolo, Gabriel Pimenta Freire","doi":"10.2174/2666862901666230419092405","DOIUrl":"https://doi.org/10.2174/2666862901666230419092405","url":null,"abstract":"\u0000\u0000Given the lack of options for treating infectious diseases, it is urgent to\u0000explore new antimicrobials. Plant food historically represents relevant sources of antimicrobial\u0000molecules.\u0000\u0000\u0000\u0000Here, we show that green tea can eradicate biofilms and planktonic cells of clinical\u0000isolates of Staphylococcus aureus and Pseudomonas aeruginosa.\u0000\u0000\u0000\u0000\u0000We conducted in vitro antimicrobial activity tests (MIC, MBC, MBEC). Cytotoxicity\u0000tests were conducted using BGM cells. We used UPLC and GC-MS to detect flavonoids and other relevant phytomolecules. The antioxidant potential was assessed using the β-carotene bleaching\u0000test. The extract was combined to clinically relevant antimicrobial drugs in vitro to investigate\u0000possible synergism or antagonism.\u0000\u0000\u0000\u0000\u0000To the best of our knowledge, MIC values are among the lowest ever described for the\u0000alcoholic extract (8 µg/mL). The extract presented elevated antioxidant potential and was not\u0000toxic to BGM cells. When the extract was combined to clinically relevant antimicrobial drugs,\u0000statistically significant antagonism was frequent for the drugs used against S. aureus isolates,\u0000whilst significant synergism was observed for some drugs used against P. aeruginosa isolates.\u0000\u0000\u0000\u0000Our data open doors for exploring isolated molecules from green tea extract against\u0000bacterial biofilms, and for developing formulations for clinical treatments.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128360706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meet the Editorial Board Member","authors":"P. Pathare","doi":"10.2174/266686290101230625142605","DOIUrl":"https://doi.org/10.2174/266686290101230625142605","url":null,"abstract":"<jats:sec>\u0000<jats:title />\u0000<jats:p />\u0000</jats:sec>","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116993595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological Investigation on Unraveling Mechanism of Action of Qusqualis indica Leaves for Predicted Treatment of Peptic Ulcer Disease","authors":"M. Kulshreshtha, Rajaneesh Kumar Chaudhary, Supriya Roy, Karuna Shanker Shukla, Anita Singh, Manjul Pratap Singh","doi":"10.2174/2666862901666230320103455","DOIUrl":"https://doi.org/10.2174/2666862901666230320103455","url":null,"abstract":"\u0000\u0000With the aid of various ulcer-induced models, the goal of this study was to assess the antiulcer ability of Qusqualis indica (Q. indica) leaf extracts in Wistar rats\u0000\u0000\u0000\u0000The induction of ulcers was done by different models like pylorus ligation method, ethanol-induced and stress-induced models. Group 1 (negative control), Group 2 (standard group) were treated with Sucralfate (8.6 mg/kg), Group 3 was treated with aqueous extract of Q. indica (AEQI,200 mg/kg), Group 4 was treated with aqueous extract of Q. indica (AEQI,400 mg/kg), Group 5 was treated with ethanolic extract of Q. indica (EEQI, 200 mg/kg) and Group 6 was treated with ethanol extract of Q. indica (EEQI, 400 mg/kg). All therapies were given orally twice every day. After the course of treatment was complete, blood and gastrointestinal contents were taken, and biochemical tests were run. The acetylcholine and histamine drug response curves were used to develop the mechanism of the extracts.\u0000\u0000\u0000\u0000The groups treated with extracts experienced a significant decrease in ulcer index. The antiulcer potential of the AEQI and EEQI is dose-dependent. Hematological, hepatic, and cardiac parameters were not significantly affected by the extracts, although high-density lipoprotein production was. Acetylcholine and histamine are blocked by AEQI and EEQI, according to the DRC analysis. The obtained scientific facts are amply supported by histopathological analysis\u0000\u0000\u0000\u0000AEQI and EEQI have antiulcer potential in a dose-dependent manner, but further research must be needed.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129305307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Food fortification using Essential fatty acids and Antioxidants: A Short Review","authors":"Sameera A. Rege, Megha A. Varshneya, S. Momin","doi":"10.2174/2666862901666230221141827","DOIUrl":"https://doi.org/10.2174/2666862901666230221141827","url":null,"abstract":"\u0000\u0000‘Health is wealth’ is an old saying. It implies that good health is more important than wealth. Food influences health conditions. A balanced nutritious diet is the key to good health. Consumption of non-nutritious food causes malnutrition because of insufficient nutrients. Prolonged deficiencies of certain nutrients lead to serious problems. When the deficiencies are detected, they can be recovered by proper supplementation based on medical prescription in proper doses, i.e., through tablets or injections. It is advisable to avoid such deficiencies by having a nutritious diet. In this context, functional food can be designed to cater to consumers’ needs. Functional food is designed via fortification of food by adding certain nutraceuticals, such as vitamins and essential fatty acids, in a proper proportion. The added nutrients should give a synergistic effect so that the nutritive value of the food can be elevated. Essential fatty acids play a vital role in the progress of the physical and mental health of the human beings. The degradation of the properties of essential fatty acids can be prevented by using antioxidants. In this review paper, the design of functional foods by using essential fatty acids and antioxidants is discussed. The synergistic effect of beneficial activities of essential fatty acids and antioxidants can be achieved in a single functional food.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116845334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacognostical, Phytochemical, In vitro Anti-obesity Studies, and Toxicity Analysis of Momordica charantia Linnaeus Fruits from Haryana","authors":"Vinesh Dahiya, N. Vasudeva, Sunil Sharma, Anil Kumar","doi":"10.2174/2666862901666230217091237","DOIUrl":"https://doi.org/10.2174/2666862901666230217091237","url":null,"abstract":"\u0000\u0000Momordica charantia Linnaeus (Cucurbitaceae family), known as bitter melon is an annual climbing vine, which grows in tropical regions and its fruits are consumed as a vegetable in Asian countries. Traditionally various parts of the plant such as fruits, seeds, leaves, flowers, etc. have been used for medicinal purposes. Its fruit is used as an anti-diabetic, laxative, anthelmintic, emetic, and anti-obesity, for respiratory problems, ulcers, wounds, rheumatism, gout, toothache, and skin diseases.\u0000\u0000\u0000\u0000Background: Momordica charantia Linn. (Cucurbitaceae family), popularly known as bitter melon is an annual climbing vine; commonly found in the tropical regions and is consumed as vegetable in Asian countries. It has traditionally been used as a medicinal herb in many parts of the world. It grows well in China, Brazil, Africa, India and South East Asian countries, etc. Its fruit is widely used to lower down blood glucose levels in diabetic patients and several pharmacological studies have been done on this herb to confirm its traditional uses.\u0000\u0000\u0000\u0000To perform pharmacognostical evaluation, qualitative and quantitative phytochemical screening, safety and toxicity studies, and in vitro anti-obesity activity evaluation on bitter gourd fruits from Haryana (India).\u0000\u0000\u0000\u0000To perform the Pharmacognostical evaluation, qualitative and quantitative phytochemical screening, safety and toxicity studies and in-vitro anti-obesity activity evaluation on bitter gourd fruits from Haryana (India).\u0000\u0000\u0000\u0000Organoleptic studies were performed with the naked eye and microscopical studies were performed using the EVOS microscope; physicochemical evaluation, microbial, and mycotoxin studies were performed by adopting the standard procedures detailed in the WHO guidelines (2011); phytochemical screening was performed by following the standard procedures; pesticide residue determination was performed by using GCMS; and in vitro anti-obesity evaluation consisting of in vitro pancreatic lipase, α-amylase, and α-glucosidase evaluation was performed by following the standard procedures.\u0000\u0000\u0000\u0000The pharmacognostical standards i.e. macroscopy, microscopy, and physicochemical analyses of the fruits were established and their qualitative and quantitative phytochemical contents revealed the presence of alkaloids, glycosides, flavonoids, tannins, proteins, and amino acids, carbohydrates, fats, and fixed oils, sterols, and triterpenoids, etc. The fruit was found to be free from mycotoxin, microbial contamination, and harmful pesticide residues. The major pesticides found to be present in fruit extract were alpha-BHC, Aldrin, 4, 4’-DDE, Endrin, and4, 4'-DDD and they were present within permissible limits. The total phenolic content in the fruits was found to be 3.49±1.3mg/g gallic acid equivalent/100g. The content of total flavonoids have been expressed as quercetin, catechin, and rutin equivalents, i.e., 1.88±0.16, 122.7±13.8 and 1.978±0.006 mg/g dry weight of fruits respectively and they were prese","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116530097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential oncotherapeutic effects of nutraceuticals against hepatocellular carcinoma: recent advancements","authors":"Sanchari Bhattacharya, Arghadip Das, Suprava Das, Debjeet Sur, Samrat Bose, Tilottama Mukherjee","doi":"10.2174/2666862901666230215115849","DOIUrl":"https://doi.org/10.2174/2666862901666230215115849","url":null,"abstract":"\u0000\u0000Worldwide, Hepatocellular carcinoma (HCC) is a frequently diagnosed cancer, having significant variations in its epidemiology. It ranks as the sixth prevailing neoplasm and is considered the third leading cause of mortality due to cancer. It accounts for 90% of primary liver cancers. Till date, an effective prevention or treatment is absent except for liver resection, chemotherapy and a frequently applied drug -sorafenib. Recently, various plant products and nutraceuticals are found to be effective in the treatment of HCC.\u0000‘Nutraceuticals’ is a term that brings into light the two giants of health sciences – nutrient and pharmaceutical. Nutraceuticals provide medical or health benefits and include prevention or treatment of a disease. These are generally ‘functional foods’, which are whole, or ‘fortified, enriched and enhanced’ in nutritional value to satisfy the required amount of essential nutrients and to confer health benefits.\u0000\u0000\u0000\u0000This study is based on the recent advancements achieved in the field of HCC treatment using a variety of emerging nutraceuticals that are effective, solely, or act as an adjuvant in its treatment. Nutraceuticals such as standardized extracts of ginger, fucoidan, curcumin, pro-anthocyanidins, epigallocatechin gallate, apigenin and other nutraceuticals are being studied extensively for their efficacy against HCC along with their proposed mechanism of action or potential targets for the treatment or prevention of HCC.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117199665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}