Current Functional Foods最新文献

{"title":"Therapeutic Significance of Cornin in Medicine for Their Biological Importance and Pharmacological Activity: An Overview of Iridoid Glycosides of Verbena Officinalis L.","authors":"K. Patel, D. Patel","doi":"10.2174/0126668629277718240101095407","DOIUrl":"https://doi.org/10.2174/0126668629277718240101095407","url":null,"abstract":"\u0000\u0000Plant products have been used for the treatment of numerous kinds of\u0000human disorders since the very ancient age. Iridoid glycosides are secondary plant metabolites of\u0000medicinal importance that have been well investigated in the scientific field for their role in plants.\u0000Numerous iridoid class phytochemicals have cardiovascular, anti-viral, anti-hepatotoxic, anti-inflammatory,\u0000anti-cancer, immunomodulatory, anti-spasmodic, hypolipidemic, choleretic, purgative,\u0000and hypoglycaemic activity.\u0000\u0000\u0000\u0000Here in the present work, we have collected scientific information on cornin and presented\u0000it with respect to its medicinal importance and pharmacological activities with their analytical\u0000aspects. Scientific information on cornin has been collected from numerous scientific databases\u0000such as PubMed, Science Direct, Google, and Scopus to know the biological potential of\u0000cornin in medicine. Further, pharmacological activity scientific data of cornin has been presented\u0000in this work with proper citations.\u0000\u0000\u0000\u0000The scientific data of the present paper described the biological significance of cornin in\u0000medicine. The further detailed pharmacological activity of cornin signified its therapeutic effectiveness\u0000on cerebral ischemia, angiogenesis, autophagy, myocardial injury, cerebral injury, oxidative\u0000injury, lipid peroxidation, proliferation, and cytochrome p450. Analytical data signified the\u0000separation, isolation, and identification techniques of cornin in medicine.\u0000\u0000\u0000\u0000The scientific information of the present work will be beneficial for all scientific\u0000people to explore the therapeutic effectiveness of cornin in medicine.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"50 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140493120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beneficial Effects of Spirulina on Brain Health: A Systematic Review","authors":"Shivendra Kumar, S. Saha, Kuldeep Singh, Talever Singh, Avinash Kumar Miahra, Brajnandan Dubey, Shubham Singh","doi":"10.2174/0126668629269256231222092721","DOIUrl":"https://doi.org/10.2174/0126668629269256231222092721","url":null,"abstract":"\u0000\u0000This review provides a concise overview of existing scientific research concerning the potential advantages of incorporating spirulina, a blue-green algae, into one's diet to promote brain health. The substantial nutritional composition and associated health benefits of algae have drawn significant interest.\u0000\u0000\u0000\u0000\u0000Numerous studies have illuminated the neuroprotective characteristics of spirulina, contributing to its positive influence on brain functionality. Primarily, spirulina boasts antioxi-dants, like phycocyanin and beta-carotene, that effectively counter oxidative stress and curb in-flammation within the brain. This is particularly significant as these factors play roles in the ad-vancement of neurodegenerative conditions like Parkinson's and Alzheimer's disease. Additional-ly, spirulina has demonstrated the capacity to enhance cognitive capabilities and enrich memory and learning aptitudes.\u0000\u0000\u0000\u0000\u0000Animal-based investigations have revealed that introducing spirulina can bolster spatial learning and memory, as well as guard against cognitive decline linked to aging. Research has in-dicated its potential in shielding against neurotoxins, encompassing heavy metals and specific en-vironmental pollutants. Its potential to neutralize heavy metals and counteract free radicals con-tributes to these protective effects, potentially thwarting neuronal harm.\u0000\u0000\u0000\u0000\u0000In conclusion, the extant scientific literature proposes that spirulina integration can elicit advantageous outcomes for brain health. Its antioxidative, neuroprotective, cognitive-enhancing, and mood-regulating properties present a promising avenue for bolstering brain health and potentially diminishing the susceptibility to neurodegenerative ailments. Nonetheless, further research, notably well-designed human clinical trials, is imperative to ascertain the optimal dos-ing, duration, and enduring consequences of spirulina supplementation concerning brain health.\u0000\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"60 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139532551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Study of Allium Sativum Linn","authors":"Roshan Sah, Manish Pal Singh, K. Gohil","doi":"10.2174/0126668629259652231108112909","DOIUrl":"https://doi.org/10.2174/0126668629259652231108112909","url":null,"abstract":"Allium sativum, commonly known as garlic, has been employed for ages for both cui-sines and restorative purposes. Many sulfur-containing phytochemical constituents are abundant in garlic and they are responsible for its many pharmacological properties. The most extensively studied compound in garlic is allicin, however, other forms of garlic such as aged garlic, raw garlic, and oil maceration of garlic, have their own unique chemical properties. Garlic has been shown to lower blood pressure, reduce cholesterol levels, improve insulin sensitivity, inhibit cell prolifera-tion, enhance peristalsis motion, modulate acetylcholine, and inhibit lipid oxidation. Apart from all its traditional therapeutic activity, it has much more potential for further study such as cancer treatment with lesser side-effects, improving mitochondrial dysfunction in Huntington’s disease, enhancement psoriasis treatment, affinity to treat glomerular disease, and vast scope in polycystic ovary syndrome and in uterine contraction. This review talks about pharmacology activities, future aspects, phytochemicals, and the privileged aspects of Allium sativum.","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139211034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tarumã-do-Cerrado (Vitex cymosa Bertero ex Spreng) for Food Diversity and Nutraceutical Products","authors":"C. R. Ballard, P. Santos, E. F. Dos Santos, Valter Aragão do Nascimento, Renato Grimaldi, C. B. Cazarin, Julian Martínez, M. R. Maróstica Jr.","doi":"10.2174/0126668629267914231025081551","DOIUrl":"https://doi.org/10.2174/0126668629267914231025081551","url":null,"abstract":"Tarumã-do-Cerrado (Vitex cymosa Bertero ex Spreng, TC) is a littleexplored Brazilian native fruit. The sustainable bioprospecting of new fruits is essential to devise strategies for preventing and treating noncommunicable diseases, like obesity, and even contribute to food diversity and discovering functional ingredients. This study evaluated the proximate composition, minerals, dietary fiber, and their fractions, phenolic compounds by two types of extraction, and antioxidant activity in the TC edible part. We also determined its fatty acid profile from the seed’s crude oil. TC has 100 g low-fat content (0.19 g) containing good phosphorus (91.50 mg) source and is rich in chromium (0.05 mg) and molybdenum (0.53 mg). It has a high range of dietary fiber in fresh and freeze-dried fruit (4.01 g and 26.23 g, respectively). The different extraction conditions showed medium to high content (101.58 to 598.80 µg GAE/100 g) of phenolic compounds. Antioxidant activity has been demonstrated in vitro using electron or hydrogen/proton transfer mechanisms. The crude oilseed is a source of oleic (35.91%) and linoleic acid (32.20%). TC provides essential nutrients, fibers, and bioactive compounds to be allied to sustainable health strategies for food diversity and nutraceutical product development.","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"65 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139242010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bifidobacterial Postbiotics as Health-promoting Agents in Dairy Products","authors":"A. Homayouni‐Rad, Saba Kamalledin Moghadam, A. Mortazavian, Soheila Abachi, S. Allahmadadi","doi":"10.2174/2666862901666230818093034","DOIUrl":"https://doi.org/10.2174/2666862901666230818093034","url":null,"abstract":"\u0000\u0000Bifidobacteria is a commercial probiotic that is widely used in industries. However, due to its oxygen-sensitive nature, industries have faced some limitations during the addition of the products. Recently it was stated that the metabolites secreted by bifidobacteria have a key role in improving health.\u0000\u0000\u0000\u0000The possibility of a postbiotic replacement for probiotics in dairy industries and its effect on health are discussed.\u0000\u0000\u0000\u0000the keywords including postbiotic, probiotic, dairy, bifidobacteria, inactivated bifidobacteria, bifidobacteria metabolites, the effect of bifidobacteria on psychology, human health, cancer, and inflammation are searched on Google Scholar as well as more than 600 research and review articles are read.\u0000\u0000\u0000\u0000Bifidobacteria could change gut bacteria positively and improve health directly. Also, the metabolites produced by bifidobacteria indirectly have wide-range effects on health.\u0000\u0000\u0000\u0000Due to the anaerobic nature of bifidobacteria, applying a postbiotic / non-viable form of bifidobacteria is a sagacious option in dairy products.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126165652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemical, Microbiological, and Sensorial Properties of Bio-ayran Prepared using various Cultures","authors":"A. M. Hassan, Ola Shalabi, M. Ismail, R. El-Menawy","doi":"10.2174/2666862901666230816091020","DOIUrl":"https://doi.org/10.2174/2666862901666230816091020","url":null,"abstract":"\u0000\u0000Four treatments of ayran were made using classic yogurt culture (T1), ABT-5 culture (T2), exopolysaccharide (EPS) producing culture (YO-Flex Mild 1.0) (T3), and EPS-producing culture + Bifidobacterium animalis subsp. lactis BB12 (mixture culture) (T4).\u0000\u0000\u0000\u0000Sample T2 had the lowest acidity values during the fermentation period. While sample T2 had the highest pH values, the total solids, fat, and total protein contents of the ayran treatments were unaffected by culture type. Mineral contents slightly decreased in samples T3 and T4. In comparison to other treatments, sample 4 had higher counts of S. thermophilus, L. delbrueckii subsp. bulgaricus, and Bifidobacterium. The recommended level of probiotic bacteria (107 cfu g−1) was exceeded for all treatments, particularly T4, and remained above (107 cfu g−1) until the end of storage. Moreover, Ayran, made with mixture culture (T4), received the highest sensory evaluation scores.\u0000\u0000\u0000\u0000Mixture culture (EPS-producing culture + BB12) is a good starter to make bioayran containing high counts of probiotics.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126407033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacognostical, Physicochemical Evaluation, and in vitro Anti-obesity Investigation of Citrullus Colocynthis Linn. Fruits from Western Haryana","authors":"Vinesh Dahiya, N. Vasudeva, Sunil Sharma, Anil Kumar","doi":"10.2174/2666862901666230810115238","DOIUrl":"https://doi.org/10.2174/2666862901666230810115238","url":null,"abstract":"\u0000\u0000Cucurbitaceae family plants have been widely used as traditional medicines for the prevention and treatment of many ailments. Citrullus colocynthis Linnaeus also known as Colocynth, is a bitter plant commonly found growing in sandy deserts around the world, and it grows naturally in the Western Haryana region. Fruits of this plant have been utilized traditionally for various medicinal purposes, like as an appetite suppressant, hypoglycemic, diuretic, laxative, anthelmintic, and for treating renal stones.\u0000\u0000\u0000\u0000The objective of this study is to carry out the in vitro anti-obesity investigation, pharmacognostical studies, heavy metal and pesticide residue analysis, microbial contamination, and mycotoxins evaluation of the Citrullus colocynthis fruits for establishing their quality, safety, efficacy, and purity standards.\u0000\u0000\u0000\u0000Fresh fruits were collected and taxonomically authenticated. The pharmacognostical characteristics of the intact and powdered fruits were identified and qualitative and quantitative phytochemical evaluation was performed. Physicochemical evaluation, heavy metal and pesticide residue detection, microbial contamination, and mycotoxins analysis were performed as per WHO guidelines 2011. In vitro inhibition activities for pancreatic lipase and α-amylase enzymes were carried out as per standard procedures and IC50 values were recorded.\u0000\u0000\u0000\u0000The pharmacognostical standards viz. macroscopy, microscopy and physicochemical parameters were laid, and the drug was declared free from microbial contamination and mycotoxins. Heavy metal analysis and pesticide residue detection revealed that their presence was below toxic levels. The Powder microscopy, microbial contamination, mycotoxin evaluation, and pesticide residue of the Colocynth fruits are novel findings. The IC50 values (µg/ml) for pancreatic lipase inhibition for aqueous and ethanolic extracts were found to be 21.27±1.25 and 34.35±1.86, and for α-glucosidase, the values were 271.12±2.64 and 283.21±3.06, and for α-glucosidase, the values were 295.67±2.92 and 306.15±3.44 respectively. Thus, the fruit extracts showed significant in vitro anti-obesity potential.\u0000\u0000\u0000\u0000Pharmacognostical and physicochemical studies prove to be useful in reducing commercial adulteration of the crude drug by assuring their purity and identity and this could further help in improving the quality of formulations incorporating it. The results of various standardization parameters could be used for designing the monograph of the crude drug. The fruits were found to be fit for therapeutic consumption and their extracts have shown good pancreatic lipase inhibition. The in vitro anti-obesity investigation findings of the fruit extracts can further be explored in-vivo for evaluating their therapeutic efficacy.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115486811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the Rutin on Diabetic Complications","authors":"Yashodhara Gaur, Shivendra Kumar, J. Gupta, Kuldeep Singh, S. Saha, S. Mukherjee","doi":"10.2174/2666862901666230803093458","DOIUrl":"https://doi.org/10.2174/2666862901666230803093458","url":null,"abstract":"\u0000\u0000Diabetes is spread all over the world and frequently causes side effects, such as neuropathy, eye disease, kidney disease, and cardiovascular disease. The patient's life span is shortened by these problems. Numerous fruits and vegetables contain the naturally active flavonoid rutin. It has several medicinal benefits, including anti-inflammatory, antioxidant, and anticancer properties. Different researches suggest that rutin may be useful in treating these problems. The purpose of this study was to investigate the connection between the administration of rutin and the complications of diabetes. According to this study, rutin has both preventive and therapeutic effects on the side effects of diabetes as it lowers oxidative stress, inflammation., and apoptosis in animal models. To completely comprehend the preventive and therapeutic benefits of rutin in diabetic patients, more clinical study is necessary.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123918250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hand-in-glove effect of Piperine in anti-cancer formulations","authors":"P. Kriplani, Jatin Kumar, Kumar Guarve","doi":"10.2174/2666862901666230727104158","DOIUrl":"https://doi.org/10.2174/2666862901666230727104158","url":null,"abstract":"\u0000\u0000Piperine, an active constituent isolated from Piper nigrum, Piper chaba, Piper sarmentosum, Piper guineense and Piper longum which is used to cure a variety of ailments related to lung, stomach, colon, skin etc. like Alzheimer’s, Parkinson’s disease, ulcerative colitis, cancer, arthritis, inflammatory bowel diseases, diabetes etc.\u0000\u0000\u0000\u0000The objective of the review is to study the synergistic effect of piperine specially in cancer.\u0000\u0000\u0000\u0000Patents and current literature mainly emphasizing the synergistic effect of piperine along with other drugs, especially anticancer drugs was reviewed keeping in mind the scientific novelty and impact.\u0000\u0000\u0000\u0000Several synergistic combinations of piperine were explored which can be beneficial for the pharmaceutical industry.\u0000\u0000\u0000\u0000This review will assist the researchers in the preparation of novel formulations with improved efficacy cutting the cost of developing new drug molecules.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116708861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Curry Leaf: Traditional Herb and its Medicinal Profile, Multipotential Nutraceutical Properties, Phytochemistry, and Pharmacological Activity","authors":"B. Kurmi, A. Verma, Preeti Patel, Dilpreet Singh, Amrinder Singh","doi":"10.2174/2666862901666230726145427","DOIUrl":"https://doi.org/10.2174/2666862901666230726145427","url":null,"abstract":"\u0000\u0000This review briefly discusses about herbal medication, i.e., Murraya koenigii, also known as curry leaves, that have been useful in traditional medicine for centuries and natural products with different pharmacological activities. It might lead to a better knowledge of natural products' potential therapeutic effects and the creation of promising pharmaceuticals with minimal toxicity and great effectiveness for treating different ailments. The Chinese Biomedical Database (CBM), Technological Periodical Database (VIP), China National Knowledge Infrastructure (CNKI), Google Scholar, Elsevier, ScienceDirect, Sci Finder, and PubMed were used to compile the content of this review. From 1975 through 2020, data were collected. More than 23 components of M. koenigii have been discovered so far, with sterols, carbohydrates, flavonoids, and alkaloids causing the most concern. Due to its multicomponent nature, M. koenigii has a wide range of beneficial biological activities, including analgesic, anticancer, antioxidative, antimicrobial, antihypertensive, antidiabetic activities, antibacterial, and anti-inflammatory properties. This review discusses the vast details of M. koenigii (Curry leaves) and its possible medicinal use for different therapeutic purposes. The plant incorporates other essential substances, as discussed, are beneficial to remedy and deal with several ailment cures that exhibit different pharmacological actions. The accumulated ethnopharmacological details of that plant may be further helpful for the upcoming research about the said properties and use of M. koenigii.\u0000","PeriodicalId":251049,"journal":{"name":"Current Functional Foods","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117215085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}