Global Journal of Respiratory Care最新文献

{"title":"Effects of An Individualized Pulmonary Rehabilitation Program in Post-COVID Fibrosis: A Case Report","authors":"Ozge Ertan Harputlu, B. Akıncı, G. K. Aslan, Merve Oğuz, G. Okumus","doi":"10.12974/2312-5470.2023.09.02","DOIUrl":"https://doi.org/10.12974/2312-5470.2023.09.02","url":null,"abstract":"Long COVID-19 Syndrome, in addition to symptoms such as chronic cough, exertional dyspnea and fatigue, pulmonary fibrosis is presented as specific respiratory system problems. Post-COVID fibrosis is characterized by radiographic abnormalities consistent with pulmonary fibrosis. Patients with post-COVID fibrosis may benefit from pulmonary rehabilitation programs. This case report aimed to investigate the effects of an individualized pulmonary rehabilitation (PR) program on selected clinical parameters in a 46-year-old male who was diagnosed with post-COVID fibrosis. Spirometry and diffusion tests were investigated. Six-minute walk and shuttle walk tests for exercise capacity, hand-held dynamometer for quadriceps muscle strength, mMrc dyspnea scale for dyspnea, Fatigue Severity Scale for fatigue and London Chest Activity of Daily Living for activities of daily living were evaluated. An individualized PR program included breathing exercises, single-leg cycle training (for the right leg, 10 to 30 min) and bilateral neuromuscular electrical stimulation for quadriceps muscles (30 min) was prescribed 3 days a week for 8 weeks. Small but promising improvements were observed in FEV1, FVC, FEV1/FVC, DLCO, 6MWD, shuttle walk tests walking distance and time, quadriceps muscle strength, mMRC and FSS scores. PR program combined with antifibrotic therapy has the potential to improve respiratory functions, exercise capacity, muscle strength, dyspnea, fatigue, and participation in ADL in patient with post-COVID fibrosis.","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116623954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Sputum Microbiocenosis and Clinical Pattern Under Different Vaccination Protocols for Pneumococcal Infection in Patients with Bronchial Asthma","authors":"A. Protasov, M. Kostinov, A. V. Zhestkov, D. O. Gorbachev, A. Kostinov, M.E. Elner, T.A. Kozina","doi":"10.12974/2312-5470.2022.08.05","DOIUrl":"https://doi.org/10.12974/2312-5470.2022.08.05","url":null,"abstract":"Bronchial asthma is a serious public health issue. It is important to reduce the frequency of attacks for BA patients. Vaccination for pneumococcal infection is an important complementary tool that can improve the clinical pattern of bronchial asthma. The study involved 102 patients with bronchial asthma, who were monitored over 4 years. The patients were divided into 4 groups based on the vaccination scheme used for pneumococcal infection: PCV13, PPV23, PPV23/PCV13, PCV13/PPV23. Sequential vaccination with pneumococcal conjugate and polysaccharide vaccines leads to a decrease in the isolation of pneumococcus from sputum in BA patients, which has a pronounced positive effect on the clinical pattern of this disease, namely, it leads to a decrease in the frequency of attacks, the requirement for courses of antibacterial chemotherapy and hospitalizations, and therefore this vaccination protocol should be included in the standards of BA patient management.","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124386609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pneumolysis in COVID-19: A Novel Concept Derived from High Altitude Physiology","authors":"G. Zubieta-Calleja, Natalia Zubieta-DeUrioste","doi":"10.12974/2312-5470.2022.08.04","DOIUrl":"https://doi.org/10.12974/2312-5470.2022.08.04","url":null,"abstract":"The COVID-19 pandemic surprised everyone with a severe lung compromise giving rise to gasping and death from respiratory insufficiency. The understanding of lung compromise is essential to advances in the field of pneumology. It is well known that the SARS-CoV-2 adheres through its spikes to the ACE-2 receptors of type II pneumocytes and introduces its RNAm material in search of its reproduction. Pneumolysis, defined as “lung destruction”, is the mechanism whereby the virus utilizes the alveolar cells to reproduce itself and destroys them in the process. The viral “attack” leads to dysfunction of the alveolar type II cells that work in conjunction with the type I alveolar cells, and a specialized thin oxygen and carbon dioxide permeable membrane. Once the virus is inside the cell, the organism’s immune system attempts to attack the virus, causing significant inflammatory reactions with remarkable ineffectiveness. The following destruction of the alveoli gives rise to a shunt, uneven ventilation-perfusion, and alteration of diffusion, generating a rapidly progressive hypoxemia that is often lethal. ","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127276281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lung Nodule and Pulmonary Fibrosis at First Evaluation in Smoker Undergoing a Smoking Cessation Program","authors":"A. Pezzuto, A. Tammaro, G. Salerno, M. Borro, E. Carico","doi":"10.12974/2312-5470.2022.08.03","DOIUrl":"https://doi.org/10.12974/2312-5470.2022.08.03","url":null,"abstract":"Smoking is the most significant avoidable risk factor. Responsible for a wide range of diseases such as cardiovascular diseases and acute or chronic respiratory diseases. \u0000It is frequently associated with interstitial pulmonary diseases and notably, it can be a cause of idiopathic pulmonary fibrosis. \u0000In this report, lung nodules and idiopathic pulmonary fibrosis were presented in a heavy smoker.","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125630778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratory Function, Physical Capacity, and Metabolic Syndrome Components in Combustible Cigarettes and Heated Tobacco Products Users: A Four-Year Follow-Up Cohort Study","authors":"A. Sharman, I. Yermakova, Elmira Erenchina, Gulnara Tyulebekova, Aisulu Bekzhanova","doi":"10.12974/2312-5470.2022.08.02","DOIUrl":"https://doi.org/10.12974/2312-5470.2022.08.02","url":null,"abstract":"Purpose: Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death worldwide and is the fourth leading cause of death in Kazakhstan. Cigarette smoking is a prevalent risk factor for COPD. While quitting smoking is the preferred way to reduce COPD risk, literature suggests that heated tobacco products (HTP) might be a better option for people who cannot quit smoking. The aim of this paper was to analyze the long-term effects of shifting to HTP use in long-term smokers compared to continued combustible cigarettes (CC) use. \u0000Patients and methods: A cohort of 1200 participants (400 HTP and 800 CC) aged 40-59 years with a minimum of 10 pack-year smoking history were recruited and followed for four years. The functional outcomes compared between HTP and CC users included: (1) COPD Assessment Test (CAT); (2) post-bronchodilator lung function; (3) 6-minute walking distance (6MWD) test; and (4) metabolic syndrome components. One way ANOVA was used to compare functional outcomes between visits, while multivariable linear mixed models were used to test associations between health outcomes and smoking type (HTP vs. CC) over time. \u0000Results: Out of 1200 participants 893 (609 CC users and 284 HTP users) remained in the study by the fourth year of follow up. Comparison between functional outcomes showed that most of them have improved between visits, while lung function and fasting blood glucose levels got worse. Linear mixed models showed HTP use was associated with better functional outcomes over time compared to CC users. Lung function decrease was significantly less in HTP users, while improvements in CAT scores, waist circumference, and systolic blood pressure were significantly better compared to CC users. \u0000Conclusion: This study demonstrated that HTP users experienced it to a significantly lesser decrease in lung function compared to CC users, while demonstrating better improvements in other functional outcomes. The results of this study suggest that HTP might be a less deleterious alternative compared to CC in people with long history of CC use and who cannot quit smoking.","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116965007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral Pulmonary Fibrosis with Pulmonary Artery Agenesis (PAA): A Case Report","authors":"G. S. Di Frega","doi":"10.12974/2312-5470.2022.08.01","DOIUrl":"https://doi.org/10.12974/2312-5470.2022.08.01","url":null,"abstract":"Unilateral pulmonary artery agenesis (AUAP) is a rare clinical condition that can be seen either in isolation or in combination with other congenital vascular disorders. When isolated, the patient may be almost asymptomatic and only become aware of this anomaly through medical examinations performed for other reasons. \u0000Here we discuss the case of a female patient with chest CT evidence of unilateral fibrous thickening, with pulmonary hypoexpansion; investigations revealed the coexistence of AUAP. \u0000This clinical association is described by very rare case-reports in the literature.","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125248907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A COPD Patient Who Developed Pulmonary Fibrosis Following COVID-19: A Case Study","authors":"A. Pezzuto, G. Tonini, A. Tammaro, A. Laviano, G. Salerno, M. Ciccozzi","doi":"10.12974/2312-5470.2021.07.06","DOIUrl":"https://doi.org/10.12974/2312-5470.2021.07.06","url":null,"abstract":"The new virus called severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) causing Coronavirus disease 2019 (COVID-19) has spread to several countries and caused the current pandemic. Different types of clinical manifestations are associated with that infection. Some drugs have been approved such as anti-viral agents but the use of corticosteroids is controversial. Pulmonary fibrosis is a frequent consequence of Covid-19 that may requires a special attention and a specific follow up. Herein we report a case of a 68-years-old patient affected by SARS-Cov-2 infection complicated by pulmonary fibrosis who healed from Covid-19 infection after a total inpatient stay of 12 days by with remdesivir treatment. The patient presented a chest fibrosis picture at the discharge that went on at 10 days check with a decline of respiratory functional parameters. For this reason a combined treatment with high dose prednisone and N-acetyl-cysteine was started. The patients benefited from high dose corticosteroids plus N-acetyl-cysteine leading to a clinical and functional improvement. Indeed, the patient underwent a chest CT-scan and spirometry at one month check after the beginning of the treatment. Notably both the radiological pattern of fibrosis and respiratory function improved after treatment with prednisone 50 mg a day for 15 days followed by 25 mg for additional 15 days and N-acetylcisteine 600 mg twice a day.","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132361286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratory Function and Physical Capacity in Combustible Cigarettes and Heated Tobacco Products Users: a Two-Year Follow-Up Cohort Study","authors":"A. Sharman, I. Yermakova, Elmira Erenchina, Gulnara Tyulebekova, Aisulu Bekzhanova","doi":"10.12974/2312-5470.2021.07.05","DOIUrl":"https://doi.org/10.12974/2312-5470.2021.07.05","url":null,"abstract":"Background: Cigarette smoking is the most common risk factor for chronic obstructive pulmonary disease (COPD), which is the fourth leading cause of death in Kazakhstan. Prior literature suggests that heated tobacco products (HTP) might be a better option for people who cannot quit smoking. The aim of this paper was to analyze the long-term effects of shifting to HTP use compared to continued combustible cigarettes (CC) use in long-term smokers. \u0000Methods: A cohort of 1200 participants (400 HTP and 800 CC) aged 40-59 years with a minimum of 10 pack-year smoking history were recruited. The functional outcomes compared between HTP and CC users included: (1) COPD Assessment Test (CAT); (2) post-bronchodilator lung function; (3) 6-minute walking distance (6MWD) test; and (4) metabolic syndrome components. Multivariable linear mixed models were used to test associations between health outcomes and smoking type (HTP vs. CC) over time. \u0000Results: After 24-month 188 (117 CC users and 71 HTP users) participants were lost to follow-up, while 107 (9%) participants quit smoking. The loss to follow-up was similar in both groups with 15% for CC users and 18% for HTP users. Liner mixed models showed HTP use was associated with lesser decrease in functional outcomes over time compared to CC users. Lung function decrease was significantly less in HTP users, while CAT scores, waist circumference, and systolic blood pressure were significantly better compared to CC users. \u0000Conclusion: This study demonstrated that while both CC and HTP users experienced decrease in lung function, HTP users experienced it to a significantly lesser degree, while demonstrating better CAT score and physical characteristics compared to CC users. The results of this study suggest that HTP might be a less deleterious alternative compared to CC in people with long history of CC use and who cannot quit smoking.","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133375530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Big Data Processing of Diagnostic Imaging Examinations Using a Self-Developed Digital Platform","authors":"Dimitrios Zarakovitis, Dimitrios Tsoromokos, A. Lazakidou","doi":"10.12974/2312-5470.2021.07.04","DOIUrl":"https://doi.org/10.12974/2312-5470.2021.07.04","url":null,"abstract":"Background: The aim of this survey is the presentation of a health information system that is eligible for processing and archiving clinical and economic health data by creating an online database that spots the origin of data on digital maps. Data concerns the cost of imaging examinations, number of hospital beds and number of clinical examinations. \u0000Methods: Geographical information Systems (GIS) can be used for the rational management of diagnostic imaging examinations and the creation of a data basement that contains clinical protocols, patients’ history and financial data. Users can exchange large volumes of the specific data very fast even between health units and hospitals. GIS Statistics enables users to estimate several financial indicators. Data concerns 5 Greek Public Health Units (H.Us) in the 6th Health Region. \u0000Results: GIS platform enables users to process big health data and share them on a geodatabase. SPSS analysis in combination with GIS statistics tools reveal an overtime increase of imaging exams in the majority of hospitals. \u0000Conclusions: The presented digital platform is a very useful tool for the rational management of clinical and financial data of healthcare units. It provides easy access to big data and enables users to gain in time data from digital maps in order to improve public health.","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117298761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adherence to Respiratory Supports in OSA and COPD","authors":"M. R. Tumolo, C. Leo, S. Sabina, Giuseppe Ponzini, Eugenio Sabato, P. Mincarone","doi":"10.12974/2312-5470.2021.07.02","DOIUrl":"https://doi.org/10.12974/2312-5470.2021.07.02","url":null,"abstract":"Chronic respiratory diseases constitute a serious public health problem in all countries, and Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are two of the most prevalent. Positive airway pressure (PAP) is recommended for ongoing treatment of OSA in adults while Long-term oxygen therapy (LTOT) is indicated for stable COPD patients with Chronic Respiratory Insufficiency. In real contexts, the clinical efficacy of these therapies is limited by an often-low adherence with consequent rising back of symptoms and adverse consequences on the quality of life. Until now, several driving factors have been identified for a low adherence to CPAP and LTOT and several solutions are proposed in many papers. In this review we identify and discuss the driving factors reported for a low adherence (addressing personal conditions, social context and specificities of the device) and the strategies adopted to mitigate them (behavioral, educational and supportive interventions) and to monitor actual compliance (self-reporting, eHealth solutions and consumptions of device accessories). An overall picture of these aspects allows planning the healthcare service and adequate support for OSA and COPD patients with an attention to the individual, social and cultural level. Further investigation is still needed to explore the value of combinations of the reported approaches on different patient phenotypes and at what cost. ","PeriodicalId":245488,"journal":{"name":"Global Journal of Respiratory Care","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121864870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}