Analytica Chimica Acta最新文献

{"title":"Mapping human fingerprint beyond level-3 based on an amphiphilic aggregation-induced emission luminogen and the construction of intelligent platform for personal identification","authors":"Xinyi Zhao ,&nbsp;Zixuan Wang ,&nbsp;Haoran Liu ,&nbsp;Siyu Yan ,&nbsp;Zihan Liu ,&nbsp;Yuai Duan ,&nbsp;Tianyu Han ,&nbsp;Tiandong Han","doi":"10.1016/j.aca.2025.343927","DOIUrl":"10.1016/j.aca.2025.343927","url":null,"abstract":"<div><h3>Background</h3><div>Fluorescence imaging agents have been benefiting tremendously from tailor-made aggregation-induced emission (AIE) luminogens, owing to their high on-off ratio, large signal contrast, low background noise as well as the resistance to photobleaching. In the domain of fingerprint imaging, AIE luminogens are beginning to exhibit an advantage owing to the aforementioned superiorities.</div></div><div><h3>Results</h3><div>We present an amphiphilic benzoic-acid salicylaldehyde AIE luminogen <strong>AIE-BASB</strong>, and outline its water sensitivity, self-assembly behavior as well as fingerprint imaging properties. <strong>AIE-BASB</strong> self-assembles into nanoscale textures when fabricated into a drop-casting film but undergoes a disassembly process in response to trace water on fingertip upon physical-contacting. Owing to the biological textures on the skin, fingerprint image can be clearly recorded by <strong>AIE-BASB</strong> film, which reveals detailed microscopic features of fingerprint information ranging from level-1 to level-3. Furthermore, it allows accurate measurements of the sizes, shapes, centroids, and areas of the sweat pores, which leads the fingerprint information into the next level. In addition, we develop an intelligent system based on <strong>AIE-BASB</strong> by integrating hardware and software modules, which is capable of recording and identifying fingerprint. After inputting fingerprint segments in trial operation, this intelligent system makes identification by calculation of the categorical probability, and successfully predicts the classification of the undefined fingerprint segments, implying 100 % accuracy in fingerprint identification.</div></div><div><h3>Significance</h3><div>We predict that <strong>AIE-BASB</strong> may facilitate the development of new biometric technologies, which have broad applications in the domain of artificial intelligence, including machine tactility, target perception and object-machine interaction.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343927"},"PeriodicalIF":5.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143590241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasensitive electrochemical sensor for lipopolysaccharide detection catalyzed by 3,4,9,10-perylenetetracarboxylic diimide","authors":"Wenjie Yu ,&nbsp;Shuaibing Yu ,&nbsp;Fenghong Zhang ,&nbsp;Qinyuan Xu ,&nbsp;Xueji Zhang ,&nbsp;Jinming Kong","doi":"10.1016/j.aca.2025.343926","DOIUrl":"10.1016/j.aca.2025.343926","url":null,"abstract":"<div><h3>Background</h3><div>Lipopolysaccharide (LPS), a bacterial endotoxin prevalent in Gram-negative pathogens (e.g., <em>Escherichia coli</em>), induces severe immune responses linked to endotoxemia and hepatitis. Despite its clinical significance, conventional LPS detection methods (e.g., limulus amebocyte lysate assays) face challenges including operational complexity, high cost, and limited sensitivity. Addressing these limitations necessitates the development of innovative strategies for ultrasensitive LPS quantification.</div></div><div><h3>Results</h3><div>We present an electrochemical biosensor integrating dual-signal amplification: (1) affinity amplification via phenylboronic acid-cis-diol covalent binding on LPS polysaccharide chains, and (2) photocatalytic amplification using perylene diimide (PDI)-mediated atom transfer radical polymerization (Photo-ATRP) under red light (615–650 nm). Thiol-functionalized DNA aptamers enable specific LPS capture, while PDI catalyzes rapid ferrocene monomer polymerization, achieving exponential signal enhancement. The sensor demonstrates exceptional performance: (1) Ultrahigh sensitivity: Detection limit of 0.25 fg/mL. (2) Wide dynamic range: Linear response from 1.0 fg/mL to 0.1 pg/mL. (3) Robust specificity: Minimal interference in human serum matrices.</div></div><div><h3>Significance</h3><div>This work establishes a paradigm for LPS detection through three key advances: (1) Operational simplicity: Eliminates enzymatic/nanomaterial dependencies via metal-free PDI photocatalysis. (2) Translational utility: Serum compatibility supports clinical diagnostics and point-of-care applications. (3) Catalytic innovation: Validates PDI as a high-efficiency photocatalyst for controlled polymer synthesis. The sensor's low-cost fabrication, rapid response (&lt;4.5 h), and femtomolar sensitivity position it as a transformative tool for sepsis monitoring and biomedical research.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343926"},"PeriodicalIF":5.7,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143590206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A washing-less biosensor based on the dual functions of magnetic separation and signal output of magnetic nanoparticles for the rapid and visual detection of enrofloxacin","authors":"Jiangqi Wang ,&nbsp;Yafang Shen ,&nbsp;Guijie Hao ,&nbsp;Xingyue Tang ,&nbsp;Huang Dai ,&nbsp;Haiqi Zhang ,&nbsp;Qingman Yang ,&nbsp;Dongren Zhou","doi":"10.1016/j.aca.2025.343923","DOIUrl":"10.1016/j.aca.2025.343923","url":null,"abstract":"<div><h3>Background</h3><div>There is an urgent need for <em>in-situ</em> detection of antibiotic residues to enhance both food safety and environmental sustainability. Although various biosensing methods have been elaborately designed and achieved extremely high sensitivities, they are always complicated and require sophisticated instruments, making them unsuitable for on-site application. Herein, a simple and washing-less biosensor that took full advantage of magnetic nanoparticles (MNs), <em>i.e</em>., magnetic separation and signal output, was developed for the rapid and sensitive detection of enrofloxacin (ENR) residues.</div></div><div><h3>Results</h3><div>The surface of MNs with diameters of approximately 20 nm (MN₂₀) and 130 nm (MN₁₃₀) were modified with ENR and antibodies to prepare MN₂₀-ENR and immunomagnetic nanoparticles (IMN₁₃₀), respectively. In the absence of ENR, the MN₂₀-ENR analogues were captured on the surface of IMN₁₃₀, forming “MN₂₀-ENR-IMN₁₃₀” complexes, which were larger in volume and could be quickly separated in a magnetic field. While in the presence of ENR, the target ENR competed for the binding sites on IMN₁₃₀ surface, inhibiting the formation of the “MN₂₀-ENR-IMN₁₃₀” structures. Therefore, the separation speed significantly slowed down. Qualitative or semi-quantitative determination of ENR residues could be achieved via visual observation of the color changes, while quantitative detection was also achieved with the aid of a microplate reader or merely a smartphone. The developed method enabled sensitive, selective and rapid detection of ENR with a limit of detection of 0.18 ng mL⁻¹ and a detection time of 25 min.</div></div><div><h3>Significance</h3><div>This method uses MNs for both magnetic separation and signal output, simplifies the detection process and eliminates the use of sophisticated instruments, providing a powerful tool for the rapid and <em>in-situ</em> detection ENR residues in various fields such as food safety and environmental protection.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343923"},"PeriodicalIF":5.7,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hand in hand catalytic hairpin assembly-based FÖrster resonance energy transfer biosensor for simultaneous detection of multiple MicroRNAs from breast cancer","authors":"Noshin Afshan ,&nbsp;Tao Cheng ,&nbsp;Jiabao Yu ,&nbsp;Ke Jiao ,&nbsp;Lie Li ,&nbsp;Jianwei Jiao ,&nbsp;Jin Jiao","doi":"10.1016/j.aca.2025.343925","DOIUrl":"10.1016/j.aca.2025.343925","url":null,"abstract":"<div><h3>Background</h3><div>The early breast cancer diagnosis is a great challenge for the treatment success. Traditional FRET biosensors often rely on a one-to-one output pattern, meaning that each target biomarker generates a single fluorescence signal, limiting both the analytical efficiency and diagnostic value. Furthermore, the use of single biomarker for early diagnosis has substantial drawbacks, as it often leads to incomplete or misleading results. The simultaneous detection of miR-155 and miR-105 offers a more robust and clinically relevant diagnostic tool, reducing the likelihood of false positives and allowing for a more accurate assessment of breast cancer at an early stage.</div></div><div><h3>Results</h3><div>In this work, a hand in hand catalytic hairpin assembly (CHA) centered FÖrster resonance energy transfer (HCA-FRET) biosensor is designed, which allows two-in-one analysis of breast cancer related two biomarkers. In this system, miR-155 and miR-105, which are involved in regulating the malignant proliferation of breast cancer, are designed as two inputs as the AND DNA logic gate. Hand in hand CHA amplification circuit is effectively triggered under dual miRNA (miR-155 and miR-105), and the resulting significantly high FRET detection signal is measured which satisfies the AND logic gate function for the simultaneous detection of dual miRNA allied with breast cancer. HCA-FRET biosensor is successfully applied to detect miR-155 (0.01–1000 nM) and miR-105 (0.01–1000 nM) with limit of detections as 0.02 and 0.05 pM, respectively. HCA-FRET has excellent selectivity for recognizing single base mismatches and interfering miRNAs, and shows good stability in different matrices. The FRET detection signal recorded from the serum samples of breast cancer patients is found much greater than that of the healthy controls, which effectively distinguishes breast cancer patients from the healthy persons.</div></div><div><h3>Significance</h3><div>The study reports a simple, unique HCA-FRET biosensor which undergo dual target miR-155 and miR-105 biomarkers detection enabling early breast cancer diagnosis. Compared with the traditional single marker detection or two signal output analysis methods, this strategy allows more accurate diagnosis of breast cancer patients from normal people. More importantly, through testing the clinical serum samples, we found that this method is expected to be used to distinguish breast cancer patients from normal people. Therefore, the proposed method has great potential applications for nucleic acid based clinical diagnostics.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343925"},"PeriodicalIF":5.7,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143583042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel near-infrared AIE probe for sensitive imaging of lipid droplet and dual-parameter cancer diagnosis","authors":"Cong Liu ,&nbsp;Shan He,&nbsp;Xiao-Feng Guo ,&nbsp;Hong Wang","doi":"10.1016/j.aca.2025.343916","DOIUrl":"10.1016/j.aca.2025.343916","url":null,"abstract":"<div><h3>Background</h3><div>Lipid droplets (LDs) are vital intracellular organelles for lipid storage, closely associated with various metabolic disorders and cancers. Fluorescence imaging offers a powerful, non-invasive approach to study LDs in real time, but many existing probes suffer from non-specific staining and aggregation-caused quenching (ACQ), compromising their imaging specificity and contrast.</div></div><div><h3>Result</h3><div>In this study, we synthesized a novel LD fluorescent probe <strong>TPC-AN</strong> that takes advantage of near-infrared emission, large Stokes shift, high lipophilicity, polarity response and aggregation-induced emission (AIE) characteristics. <strong>TPC-AN</strong> effectively addresses issues of non-specific staining and ACQ commonly observed with traditional probes, enabling highly specific and high-contrast imaging of LDs. Utilizing <strong>TPC-AN</strong>, imaging of LDs in several kinds of cells was performed, and discrimination of cancerous and normal cells was achieved using dual-parameter through differences in LD fluorescence area and intensity.</div></div><div><h3>Significance</h3><div>This work provides a promising tool for studying LDs in diseases and offers a reliable method for cancer diagnosis, with excellent LD-specificity, low cytotoxicity, and dual-parameter imaging capabilities.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343916"},"PeriodicalIF":5.7,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143576227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid and sensitive detection of pharmaceutical pollutants in aquaculture by aluminum foil substrate based SERS method combined with deep learning algorithm","authors":"Zixi Huang ,&nbsp;Yongqian Lei ,&nbsp;Weixin Liang ,&nbsp;Yili Cai ,&nbsp;Pengran Guo ,&nbsp;Jian Sun","doi":"10.1016/j.aca.2025.343920","DOIUrl":"10.1016/j.aca.2025.343920","url":null,"abstract":"<div><h3>Background</h3><div>Pharmaceutical residual such as antibiotics and disinfectants in aquaculture wastewater have significant potential risks for environment and human health. Surface enhanced Raman spectroscopy (SERS) has been widely used for the detection of pharmaceuticals due to its high sensitivity, low cost, and rapidity. However, it is remain a challenge for high-sensitivity SERS detection and accurate identification of complex pollutants.</div></div><div><h3>Results</h3><div>Hence, in this work, we developed an aluminum foil (AlF) based SERS detection substrate and established a multilayer perceptron (MLP) deep learning model for the rapid identification of antibiotic components in a mixture. The detection method demonstrated exceptional performance, achieving a high SERS enhancement factor of 4.2 × 10⁵ and excellent sensitivity for trace amounts of fleroxacin (2.7 × 10⁻⁸ mol/L), levofloxacin (1.95 × 10⁻⁸ mol/L), and pefloxacin (6.9 × 10⁻⁸ mol/L),sulfadiazine, methylene blue, and malachite green at a concentration of 1 × 10⁻⁸ mol/L can all be detected, the concentrations of the six target compounds and their Raman intensities exhibit a good linear relationship. Moreover, the AlF SERS substrate can be prepared rapidly without adding organic reagents, and it exhibited good reproducibility, with RSD&lt;9.6 %. Additionally, the algorithm model can accurately identify the contaminants mixture of sulfadiazine, methylene blue, and malachite green with a recognition accuracy of 97.8 %, an F1-score of 98.2 %, and a 5-fold cross validation score of 97.4 %, the interpretation analysis using Shapley Additive Explanations (SHAP) reveals that MLP model can specifically concentrate on the distribution of characteristic peaks.</div></div><div><h3>Significance</h3><div>The experimental results indicated that the MLP model demonstrated strong performance and good robustness in complex matrices. This research provides a promising detection and identification method for the antibiotics and disinfectants in actual aquaculture wastewater treatment.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1351 ","pages":"Article 343920"},"PeriodicalIF":5.7,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143576257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of disease diagnosis technology based on coattention cross-fusion of multiomics data","authors":"Mingtao Wu ,&nbsp;Chen Chen ,&nbsp;Xuguang Zhou ,&nbsp;Hao Liu ,&nbsp;Yujia Ren ,&nbsp;Jin Gu ,&nbsp;Xiaoyi Lv ,&nbsp;Cheng Chen","doi":"10.1016/j.aca.2025.343919","DOIUrl":"10.1016/j.aca.2025.343919","url":null,"abstract":"<div><h3>Background</h3><div>Early diagnosis is vital for increasing the rates of curing diseases and patient survival in medicine. With the advancement of biotechnology, the types of bioomics data are increasing. The integration of multiomics data can provide more comprehensive biological information, thereby achieving more accurate diagnoses than single-omics data can. Nevertheless, current multiomics research is often limited to the intelligent diagnosis of a single disease or a few types of omics data and lacks a multiomics disease diagnosis model that can be widely applied to different diseases. Therefore, developing a model that can effectively utilize multiomics data and accurately diagnose diseases has become an important challenge in medical research.</div></div><div><h3>Results</h3><div>On the basis of vibrational spectroscopy and metabolomics data, this study proposes an innovative coattention cross-fusion model for disease diagnosis on the basis of interactions of multiomics data. The model not only integrates the information of different omics data but also simulates the interactions between these data to achieve accurate diagnosis of diseases. Through comprehensive experiments, our method achieved accuracies of 95.00 %, 94.95 %, and 97.22 % and area under the curve (AUC) values of 95.00 %, 96.77 %, and 99.31 % on the cervical lymph node metastasis of the thyroid, systemic lupus erythematosus, and cancer datasets, respectively, indicating excellent performance in the diagnosis of multiple diseases.</div></div><div><h3>Significance</h3><div>The proposed model outperforms existing multiomics models, enhancing medical diagnostic accuracy and offering new approaches for multiomics data use in disease diagnosis. The innovative coattention cross-fusion module enables more effective multiomics data processing and analysis, serving as a potent tool for early and precise disease diagnosis with substantial clinical and research implications.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1351 ","pages":"Article 343919"},"PeriodicalIF":5.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143570265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation on effects of TiO2 on cucumber seedlings using ICP-OES and LA-ICP-MS","authors":"Yu Wang ,&nbsp;Qi Liu ,&nbsp;Zhen Shao ,&nbsp;Xue-Sheng Wang ,&nbsp;Ya-Fei Chen ,&nbsp;Jun-Jie Bai ,&nbsp;Ming-Li Chen ,&nbsp;Jian-Hua Wang","doi":"10.1016/j.aca.2025.343917","DOIUrl":"10.1016/j.aca.2025.343917","url":null,"abstract":"<div><div>With the expansion of TiO₂ applications in various fields, TiO₂ inevitably enters the soil, increasing the possibility of plant roots being exposed to high concentrations of TiO₂. Therefore, it is important to study plant growth under TiO₂ exposure conditions. In this study, the combination method of inductively coupled plasma emission spectroscopy (ICP-OES) and laser ablation inductively coupled plasma mass spectroscopy (LA-ICP-MS) was used to evaluate the effect of TiO₂ on the content and distribution of nutrient elements in different parts of cucumber seedlings. The results showed that the low concentrations (50 mg/L, 100 mg/L and 200 mg/L) of TiO₂ had gradually enhanced the growth of cucumber seedlings, while the high concentration (500 mg/L) of TiO₂ had a significant inhibitory effect on the plant. The contents of elements (Ti, K, Ca, Mg, Mn, Fe, Zn, and Cu) in cucumber seedling roots, stems and leaves incubated with 200 mg/L TiO₂ were determined by ICP-OES, and the results showed that the uptake of TiO₂ increased the content of nutrient elements in the plant. High-resolution imaging of Ti, Ca, Mg, Mn, Fe, Zn, and Cu in roots, stems, and leaves using LA-ICP-MS showed that Ti accumulated mainly at the margins of the leaves. Ca, Mg, Mn, Fe, Zn, and Cu in the leaves were mainly concentrated in the main veins and lateral veins. By evaluating the content and distribution of elements in the plant with ICP-OES and LA-ICP-MS, it provides a new idea to study the mechanism of nanoparticles in the plant. It provides a theoretical basis for the correct use of nanomaterials, which is of great significance in promoting the sustainable development of agriculture.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343917"},"PeriodicalIF":5.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143570264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid detection of organophosphorus pesticide monocrotophos by pore size-regulated amplified fluorescence “turn-on” response of Zr-MOF","authors":"Xinying Gong ,&nbsp;Yulu Tian ,&nbsp;Yuanjun Tong ,&nbsp;Yibin Yuan ,&nbsp;Shiyu Peng ,&nbsp;Dongmei Wang ,&nbsp;Hongqun Tao ,&nbsp;Qinwen Tan ,&nbsp;Zhengjun Gong","doi":"10.1016/j.aca.2025.343915","DOIUrl":"10.1016/j.aca.2025.343915","url":null,"abstract":"<div><h3>Background</h3><div>Organophosphorus pesticides pose a severe threat to human health even at trace levels in the environment, owing to their high persistence and neurotoxic effects. Rapid detection methods based on luminescent metal organic frameworks (LMOFs) have great advantages in environmental applications, attributing to their unique luminescence characteristics, structural flexibility, high porosity, and tunable synthesis. Therefore, an effective strategy for adjusting pore size in LMOFs is essential to enhance the sensitivity and selectivity of fluorescence recognition.</div></div><div><h3>Results</h3><div>In this study, a fluorescence probe NH₂-UiO-66@cur was synthesized, where curcumin was utilized to modulate the pore size of NH₂-UiO-66, resulting in a fluorescence “turn-on” response for the rapid detection of monocrotophos (MCP). The incorporation of curcumin increased the average pore size of NH₂-UiO-66 from 2.01 to 3.61 nm, thereby facilitating the mass transfer of MCP in NH₂-UiO-66@cur. Additionally, the coordinating of MCP with the zirconium node effectively block the ligand-to-metal charge transfer (LMCT) process, significantly improving sensitivity with an ultra-low detection limit of 0.41 μg L⁻¹ for MCP. The NH₂-UiO-66@cur sensor exhibited excellent selectivity for MCP compared to other organosphosphorus compounds, as well as robust interference resistance. In practical applications, the fluorescence probe showed stable and accurate detection potential, with spiking recoveries ranging from 84.2 % to 105 % in environmental water samples.</div></div><div><h3>Significance</h3><div>This work provides a novel strategy for tailoring the pore size for a MOF sensor platform, which notably enhances the mass transfer and fluorescence emission intensity by blocking LMCT effect. As a result, it improves the detection sensitivity and selectivity on trace organophosphate pollutants in the environment samples, addressing critical concerns in environmental monitoring.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343915"},"PeriodicalIF":5.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143570260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A microneedle sensor for in-vivo sodium ion detection in plants","authors":"Cheng-Xiao Fan,&nbsp;Zhuo Wang,&nbsp;Zhi-Hao Wang,&nbsp;Ao-Wen Wang,&nbsp;Zhong-Yi Wang,&nbsp;Lan Huang","doi":"10.1016/j.aca.2025.343892","DOIUrl":"10.1016/j.aca.2025.343892","url":null,"abstract":"<div><div>This study introduces a novel microneedle-type potentiometric sensor designed for the <em>in-vivo</em> detection of sodium ions (Na⁺) in plant tissues. The development of this sensor is crucial for advancing our understanding of plant responses to salinity stress. The microneedle sensor employs a highly selective Na⁺ ion carrier and integrates a solid-contact layer made of poly(3,4-ethylenedioxythiophene)-poly (sodium 4-styrenesulfonate) (PEDOT: PSS) prepared by electropolymerization. Due to its excellent conductivity and high chemical stability, PEDOT:PSS significantly reduces the surface impedance of the electrode, enhances charge transfer efficiency, and thereby improves the sensor's response sensitivity and stability. The sensor achieves a linear detection range of 1 × 10⁻² to 1 × 10⁻⁵ M, with a slope of 56.55 ± 0.25 mV/decade and a detection limit of 1.94 × 10⁻⁶ M. The fabrication process was optimized by refining the membrane formulation, ensuring precise control over membrane thickness, and determining the optimal conditioning time, all essential for large-scale production and agricultural applications. In addition, we evaluated the sensor's ability to detect Na⁺ concentration changes in both artificial culture media and actual plant tissue samples. The sensor's performance was assessed through its capability to monitor Na⁺ concentration changes in both artificial culture media and real plant tissue samples, with results benchmarked against the standard method (ICP-OES), confirming its accuracy and reliability. Moreover, application trials involving rice seedlings validated the microneedle sensor's efficacy for in vivo detection of Na⁺, providing a robust tool for understanding plant physiological responses to salt stress. These findings not only offer new insights into plant adaptation mechanisms but also establish a practical platform for selecting salt-tolerant cultivars and enabling rapid salt-level assessment in agricultural practices.</div></div>","PeriodicalId":240,"journal":{"name":"Analytica Chimica Acta","volume":"1352 ","pages":"Article 343892"},"PeriodicalIF":5.7,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}