Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko最新文献

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[Microsurgical resection of brain metastases: rationale, appropriateness and local control]. 显微外科手术切除脑转移瘤:理由、适宜性和局部控制。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro202690051106
A Kh Bekyashev, S M Banov, S R Ilyalov, E R Vetlova, A V Smolin, A A Tushev, D A Khalafyan
{"title":"[Microsurgical resection of brain metastases: rationale, appropriateness and local control].","authors":"A Kh Bekyashev, S M Banov, S R Ilyalov, E R Vetlova, A V Smolin, A A Tushev, D A Khalafyan","doi":"10.17116/neiro202690051106","DOIUrl":"https://doi.org/10.17116/neiro202690051106","url":null,"abstract":"<p><strong>Objective: </strong>To summarize data on indications for microsurgical resection of brain metastases, effect of resection technique on local control and leptomeningeal dissemination, as well as the role of stereotactic radiosurgery in improving local control.</p><p><strong>Material and methods: </strong>A descriptive review of data on surgical treatment of brain metastases was performed. We reviewed the PubMed/MEDLINE, the Cochrane Library (CENTRAL), PubMed Central, and eLIBRARY/RSCI databases between 2000 and January 2025 using the keywords \"brain metastases\", \"en bloc resection\", \"piecemeal resection\", \"local control\", \"leptomeningeal disease\", \"preoperative SRS\" and \"postoperative SRS\". Clinical studies, systematic reviews, meta-analyses, guidelines, and consensus documents were included. Studies on primary central nervous system tumors, samples ≤10 patients, and publications without extractable clinical outcomes were excluded.</p><p><strong>Results: </strong>The first part of the review considers indications for microsurgical resection in relation to clinical goals, survival and functional status. Surgery is reasonable for symptomatic large lesions, mass effect, diagnostic uncertainty, local recurrence, or complications after radiotherapy. Surgical technique should account for growth pattern of brain metastases: en bloc resection and, in selected cases, extended resection of peritumoral zone may improve local control. Retrospective data consistently associate piecemeal resection with higher risk of leptomeningeal dissemination, particularly for posterior fossa lesions and metastases adjacent to cerebrospinal fluid pathways.</p><p><strong>Conclusion. s: </strong>Urgical treatment is presented as a component of a personalized multimodal strategy. Decision-making on surgery should rely on survival prognosis and likelihood of clinically meaningful benefit. When technically feasible, en bloc resection may be considered as a preferable approach, especially when the risk of leptomeningeal dissemination is clinically relevant.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 5","pages":"106-112"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Single-portal endoscopic decompression for degenerative lumbosacral spinal stenosis: a prospective single-center study]. [单门静脉内镜减压治疗退行性腰骶椎管狭窄:一项前瞻性单中心研究]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro20269005116
L R Gabrielyan, N A Konovalov, R A Onoprienko, E S Brinyuk, S V Kaprovoy, B A Zakirov
{"title":"[Single-portal endoscopic decompression for degenerative lumbosacral spinal stenosis: a prospective single-center study].","authors":"L R Gabrielyan, N A Konovalov, R A Onoprienko, E S Brinyuk, S V Kaprovoy, B A Zakirov","doi":"10.17116/neiro20269005116","DOIUrl":"https://doi.org/10.17116/neiro20269005116","url":null,"abstract":"<p><strong>Background: </strong>Degenerative lumbosacral spinal stenosis is one of the leading causes of chronic pain and disability in elderly patients. Single-portal endoscopic interlaminar bilateral decompression is a promising minimally invasive method. However, prospective data are limited.</p><p><strong>Material and methods: </strong>A single-center prospective study included 50 patients with central single-level lumbosacral degenerative stenosis who underwent single-portal endoscopic interlaminar bilateral decompression through a unilateral approach. VAS, ODI, MacNab and GAS scores were assessed. We also analyzed surgery time and 6-month morbidity.</p><p><strong>Results: </strong>By the 6<sup>th</sup> month, VAS scores of low back and leg pain decreased by 5.6 and 6.7 points. ODI score decreased by 48.2 points (<i>p</i><0.001). Satisfactory outcomes according to MacNab scale comprised 80%, GAS ≥0 - 82%. Dural damage and explorations were observed in 4% of cases, and there were no infectious complications. Mean surgery time decreased from 230 to 127 min along with accumulation of experience (<i>p</i><0.001).</p><p><strong>Conclusion: </strong>Single-portal endoscopic interlaminar bilateral decompression from a unilateral approach is an effective option for degenerative lumbosacral stenosis. Multiple-center studies with long-term follow-up are needed to evaluate long-term outcomes and compare this surgery with other minimally invasive techniques.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 5","pages":"16-24"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Surgical treatment of anterior visual pathway gliomas in children using intraoperative neurophysiological monitoring and MR tractography]. [术中神经生理监测和MR束造影对儿童前视通路胶质瘤的外科治疗]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro20269005154
N I Golovin, S K Gorelyshev, A A Ogurtsova, R M Afandiev
{"title":"[Surgical treatment of anterior visual pathway gliomas in children using intraoperative neurophysiological monitoring and MR tractography].","authors":"N I Golovin, S K Gorelyshev, A A Ogurtsova, R M Afandiev","doi":"10.17116/neiro20269005154","DOIUrl":"10.17116/neiro20269005154","url":null,"abstract":"<p><strong>Background: </strong>Surgical resection of anterior visual pathway gliomas carries a high risk of postoperative visual deficit. The goals of surgical treatment are maximum safe removal of tumor and histological verification. Diffusion tensor imaging (DTI) with reconstruction of visual pathways and intraoperative monitoring of visual evoked potentials (VEP) were proposed to reduce the risk of potential visual dysfunction.</p><p><strong>Objective: </strong>To demonstrate two cases of surgical treatment for anterior visual pathway gliomas using preoperative MR tractography of visual pathways and intraoperative VEP monitoring.</p><p><strong>Material and methods: </strong>Two patients with anterior visual pathway tumors underwent preoperative MR tractography of visual pathways. Intraoperative VEP monitoring was performed.</p><p><strong>Results: </strong>Extent of resection in both cases was determined by preoperative MR tractography and intraoperative neurophysiological monitoring of VEP. Ophthalmological status in early postoperative period demonstrated positive dynamics in the 1<sup>st</sup> patient and no changes in the 2<sup>nd</sup> patient.</p><p><strong>Conclusion: </strong>Preoperative MR tractography of visual pathways and intraoperative neurophysiological monitoring of VEP with electrophysiological identification of visual pathways may potentially enable safer tumor resection and minimize the risk of postoperative visual deficit.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 5","pages":"54-60"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Principles of systematization and formation of surgical strategies for craniovertebral region lesions]. 颅椎区病变手术策略的系统化及形成原则
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro20269001121
V V Stepanenko, A V Trashin, V A Shamanin, K S Gordienko, Yu A Shulev, R V Khalepa, M A Kosimshoev, Yu E Kubetsky, D A Rzayev
{"title":"[Principles of systematization and formation of surgical strategies for craniovertebral region lesions].","authors":"V V Stepanenko, A V Trashin, V A Shamanin, K S Gordienko, Yu A Shulev, R V Khalepa, M A Kosimshoev, Yu E Kubetsky, D A Rzayev","doi":"10.17116/neiro20269001121","DOIUrl":"10.17116/neiro20269001121","url":null,"abstract":"<p><p>Surgical treatment of craniovertebral junction (CVJ) lesions is a complex multidisciplinary problem. Despite diverse diseases and traumatic injuries of CVJ, many authors note universality of clinical manifestations. This allows for their systematization and formation of homogeneous groups based on dominant clinical syndrome.</p><p><strong>Objective: </strong>To apply dominant clinical syndrome for systematizing CVJ lesions and formation of surgical strategies.</p><p><strong>Material and methods: </strong>A retrospective analysis and systematization of patient groups with surgical CVJ lesions were conducted in 2 neurosurgical hospitals. The study included 181 patients with one of the five main CVJ lesions. Inclusion criteria were CVJ diseases and lesions: trauma - 76 (42%), developmental anomalies - 19 (10%), inflammatory and genetic diseases - 9 (5%), extradural tumors - 27 (15%), intradural tumors - 50 (28%). Systematization of material was based on the principle of dominant clinical syndrome. Two types of dominant clinical syndrome were distinguished: compression and instability. The specialized scales were used: the White & Panjabi criteria for trauma and anomalies, the Spinal Instability Neoplastic Score (SINS) for CVJ tumors, the Ranawat scale for rheumatoid arthritis, and the Kang scale for assessing compression of medulla oblongata and spinal cord.</p><p><strong>Results: </strong>We distinguished 2 groups depending on dominant clinical syndrome: group 1 with compression (97 (54%) patients) and group 2 with instability (84 (46%) patients). Group I included 97 patients with trauma (<i>n</i>= 10, 10.3%), anomalies (<i>n</i>=16, 16.5%), inflammatory and genetic storage diseases (<i>n</i>=8, 8.2%), extradural tumors (<i>n</i>=13, 13.4%), intradural tumors (<i>n</i>=50, 51.6%). In this group, decompression was performed at the first stage. After eliminating compression of medulla oblongata and upper spinal cord, bone fixation was performed in 26 (34%) patients. Group II included 84 patients with trauma (<i>n</i>=66, 78.5%), anomalies (<i>n</i>=3, 3.5%), inflammatory and genetic storage diseases (<i>n</i>=1, 1.2%), extradural tumors (<i>n</i>=14, 16.8%). All patients underwent various fusion procedures. Of these, 17 (20.2%) patients underwent concomitant fusion and resection for extradural tumors, rheumatoid arthritis, and late sequelae of trauma.</p><p><strong>Conclusion: </strong>Anatomical, biomechanical, and clinical similarities allow for classification of surgical CVJ lesions based on dominant clinical syndrome. Identification of dominant clinical syndrome allows for appropriate surgical strategies, sequence of surgical stages and their timing.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 1","pages":"21-28"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146158556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Odontoidectomy: a systematic review]. [齿状突切除术:系统回顾]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro202690031107
I V Chernov, A N Shkarubo, D A Konyashin, M A Kutin, D V Fomichev, O I Sharipov, D N Andreev, A D Donskoy, P L Kalinin
{"title":"[Odontoidectomy: a systematic review].","authors":"I V Chernov, A N Shkarubo, D A Konyashin, M A Kutin, D V Fomichev, O I Sharipov, D N Andreev, A D Donskoy, P L Kalinin","doi":"10.17116/neiro202690031107","DOIUrl":"10.17116/neiro202690031107","url":null,"abstract":"<p><p>There is extensive experience of odontoidectomies for various lesions of craniovertebral junction worldwide. Various approaches including those through natural anatomical openings (transoral and transnasal), as well as transcervical one is used.</p><p><strong>Objective: </strong>To compare the outcomes of odontoidectomies through various approaches according to literature data.</p><p><strong>Material and methods: </strong>A systematic review was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. We reviewed the PubMed, Medline and Google Scholar databases using the keyword «odontoidectomy».</p><p><strong>Results: </strong>Analysis included 128 studies describing treatment outcomes in 688 patients. Transoral approach was used in 446 patients, transnasal - in 192, transcervical approach - in 50 patients.</p><p><strong>Conclusion: </strong>Surgical approach for odontoidectomy significantly impacts surgery time, complication rates, initiation of oral feeding and length of hospital-stay.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 3","pages":"107-114"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148017773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[First clinical application of autologous fibrin sealant Vivostat for neurosurgery in Kazakhstan and Central Asia]. [自体纤维蛋白密封剂Vivostat在哈萨克斯坦和中亚地区神经外科的首次临床应用]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro20269002170
E N Kuanyshev, B S Syzdykova, D K Teltayev, K H Mustafin
{"title":"[First clinical application of autologous fibrin sealant Vivostat for neurosurgery in Kazakhstan and Central Asia].","authors":"E N Kuanyshev, B S Syzdykova, D K Teltayev, K H Mustafin","doi":"10.17116/neiro20269002170","DOIUrl":"10.17116/neiro20269002170","url":null,"abstract":"<p><strong>Background: </strong>Watertight dural closure and skull base reconstruction remain key challenges in neurosurgery. Autologous fibrin sealant Vivostat, produced from the patient's own blood, provides high biocompatibility, elasticity, and reliable adhesion. The absence of clinical data on its use in Central Asian countries highlights the relevance of the present study.</p><p><strong>Objective: </strong>To evaluate the clinical efficacy and safety of autologous fibrin sealant Vivostat for dural sealing and skull base reconstruction.</p><p><strong>Material and methods: </strong>This retrospective-prospective study included 110 patients operated on at the National Center of Neurosurgery (Astana, Kazakhstan) between August 2024 and September 2025. The sealant, derived from autologous blood using the Vivostat system, was applied for dural defect sealing and fixation of reconstructive grafts. The primary outcomes were the incidence of postoperative cerebrospinal fluid (CSF) leakage, infectious complications, and the need for reoperation.</p><p><strong>Results: </strong>The mean patient age was 48.9±14.7 years; 60% were women. An endoscopic transnasal approach was used in 65 patients, craniotomy in 35, and other approaches in 10. Polymerization occurred almost instantly, reaching maximal strength within 1-2 minutes. Successful sealing was achieved in 109 (99.1%) patients, while 1 (0.9%) patient required reoperation due to nasal CSF leakage and epistaxis. No infectious, allergic, or thromboembolic complications were observed.</p><p><strong>Conclusion: </strong>The use of autologous fibrin sealant Vivostat demonstrated high efficacy and safety for dural sealing and skull base reconstruction. The method reduced the risk of postoperative CSF leakage and reoperation. This study presents the first clinical experience with Vivostat in Central Asia.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 2","pages":"70-76"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Endocrine inactive pituitary microadenomas: current data on natural history and follow-up approaches]. [内分泌无活性垂体微腺瘤:自然史和随访方法的当前数据]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro20269002198
D N Dzhatieva, E A Pigarova, L K Dzeranova
{"title":"[Endocrine inactive pituitary microadenomas: current data on natural history and follow-up approaches].","authors":"D N Dzhatieva, E A Pigarova, L K Dzeranova","doi":"10.17116/neiro20269002198","DOIUrl":"10.17116/neiro20269002198","url":null,"abstract":"<p><p>Endocrine inactive pituitary microadenomas are ones of the most common incidental findings in neuroimaging. Their prevalence is up to tens of cases per 100.000. According to current data, the vast majority of microadenomas remain stable over long-term follow-up, and the risk of progression, hypopituitarism, or the need for surgical intervention is extremely low. Clinical factors such as baseline adenoma size, gender and age have not proven predictive value for the risk of microadenoma growth. Current recommendations for follow-up vary significantly. There is evidence of safety of less aggressive strategies (delaying the first MRI for up to 3 years without clinical manifestations and no routine hormonal screening in patients with stable course). This approach combines clinical effectiveness and cost-effectiveness. Thus, current data allow us to consider endocrine inactive pituitary microadenomas as lesions with favorable prognosis. Revising international guidelines in favor of more rational and personalized surveillance strategies appears to be a justified and necessary step to optimize clinical practice.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 2","pages":"98-102"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sagittal balance parameters in choice of surgical strategy for degenerative lumbosacral spinal stenosis]. 矢状面平衡参数在退行性腰骶管狭窄手术策略选择中的应用。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro20269003158
D I Shtadler, V D Shtadler, G A Fukalov, M S Staroverov, E M Balakina, D D Khirevich, N A Vdovina, A A Grin
{"title":"[Sagittal balance parameters in choice of surgical strategy for degenerative lumbosacral spinal stenosis].","authors":"D I Shtadler, V D Shtadler, G A Fukalov, M S Staroverov, E M Balakina, D D Khirevich, N A Vdovina, A A Grin","doi":"10.17116/neiro20269003158","DOIUrl":"10.17116/neiro20269003158","url":null,"abstract":"<p><strong>Objective: </strong>To determine the indications for surgical correction of lumbar lordosis in patients with multilevel degenerative lumbosacral spinal stenosis.</p><p><strong>Material and methods: </strong>A prospective pilot study was conducted at the Perm City Clinical Hospital No. 4 between 2022 and 2025. Patients with multilevel degenerative lumbosacral spinal stenosis presenting with clinical manifestations of compressive syndromes, as well as persistent back pain refractory to conservative treatment, were enrolled. All patients underwent the following additional examinations: pain assessment (VAS scores), functional status (the Oswestry Disability Index and the Roland-Morris Disability Questionnaire), standing full-spine radiography with calculation of sagittal balance parameters.</p><p><strong>Results: </strong>The study group consisted of 22 patients with multilevel lumbar spinal stenosis at the following levels: L3-L4-L5 in 6 (27.3%) patients, L4-L5-S1 in 13 (59.1%) patients, and L2-L3-L4-L5 in 3 (13.6%) patients. Mean pathological reduction of lumbar lordosis relative to individual normative value was 17.8° (min 8.3°, max 22.6°). All patients underwent surgical intervention. After 3 postoperative months, standing radiographs demonstrated achievement of target lumbar lordosis along with regression of neurological symptoms in all patients. VAS score of pain decreased by 2.8 times (95% CI 1.7-4.2). Disability according to the Roland-Morris questionnaire improved by 3.3 times (95% CI 2.1-4.7). Quality of life across various domains assessed by the Oswestry Disability Index improved by 3.1 times (95% CI 1.1-3.8).</p><p><strong>Conclusion: </strong>In patients with multilevel degenerative lumbosacral spinal stenosis (Schizas grade C or D) accompanied by compressive syndromes and drug-resistant back pain, surgical interventions are indicated for reduced lumbar lordosis and impairment of at least one sagittal balance parameter, including pelvic angle, pelvic tilt, ThI pelvic angle, sagittal vertical axis. Correction of lumbar lordosis in this patient population results in significant reduction of back pain and QoL improvement.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 3","pages":"58-66"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148017700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Paragangliomas of the head and neck. Epidemiology and diagnosis]. 头颈部副神经节瘤。流行病学与诊断]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro20269005190
A D Akhmedov, V A Lukshin, S V Zolotova, D S Kim, D R Rustamova, D Yu Usachev
{"title":"[Paragangliomas of the head and neck. Epidemiology and diagnosis].","authors":"A D Akhmedov, V A Lukshin, S V Zolotova, D S Kim, D R Rustamova, D Yu Usachev","doi":"10.17116/neiro20269005190","DOIUrl":"https://doi.org/10.17116/neiro20269005190","url":null,"abstract":"<p><strong>Background: </strong>Head and neck tumors cross several clinical specialties. Diagnostic and treatment approaches vary significantly depending on specialty, and there is no a unified diagnostic standard for paragangliomas in these areas. In this report, we summarize available data on these tumors and present own patient evaluation protocol.</p><p><strong>Objective: </strong>To systematize modern information on epidemiology, pathogenesis and diagnosis of paragangliomas.</p><p><strong>Material and methods: </strong>We present literature review and retrospective analysis of instrumental and laboratory data of patients with head and neck paragangliomas.</p><p><strong>Results: </strong>We analyzed modern diagnostic methods: imaging (Doppler ultrasound, CT, MRI, PET CT), biochemical (catecholamines and their metabolites), and molecular genetic (mutation testing) tests. Advantages and limitations of each method were identified. We also present optimal algorithms for their combination for early and accurate disease detection.</p><p><strong>Conclusion: </strong>This analysis systematized the approach to diagnostic algorithm for patients with head and neck paragangliomas. The capabilities of modern imaging methods allow for identification of potentially malignant and familial forms of disease, which are fundamentally different from sporadic forms. Available data underlie a differentiated approach to treatment strategy. This positively impacts treatment outcomes. This aspect will be discussed in the second part of the article.</p>","PeriodicalId":24032,"journal":{"name":"Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko","volume":"90 5","pages":"90-99"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Surgical treatment of frontal lobe glial tumors. Current state of the problem. Part III: clinical, neurophysiological and surgical nuances]. 额叶神经胶质肿瘤的外科治疗。问题的当前状态。第三部分:临床,神经生理和外科的细微差别]。
Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko Pub Date : 2026-01-01 DOI: 10.17116/neiro202690011108
A E Bykanov, T S Bezbabicheva, D I Pitskhelauri
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