Chinese journal of otorhinolaryngology head and neck surgery最新文献

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[Horizontal sound localization in young and middle-aged patients with symmetric sensorineural hearing loss in noisy environments]. [噪声环境下中青年对称感音神经性听力损失患者的水平声定位]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20240707-00406
J S Dai, L Wei, J Y Li, X Wang, X L He, S Nie, J Zhang
{"title":"[Horizontal sound localization in young and middle-aged patients with symmetric sensorineural hearing loss in noisy environments].","authors":"J S Dai, L Wei, J Y Li, X Wang, X L He, S Nie, J Zhang","doi":"10.3760/cma.j.cn115330-20240707-00406","DOIUrl":"10.3760/cma.j.cn115330-20240707-00406","url":null,"abstract":"<p><p><b>Objective:</b> This study evaluates the horizontal sound localization ability of young and middle-aged individuals with symmetric sensorineural hearing loss (SNHL) in noisy environments. It also examines the impact of hearing loss severity and signal-to-noise ratio (SNR) on localization accuracy. <b>Methods:</b> In this cross-sectional study, conducted from April 2023 to April 2024, 135 young and middle-aged patients (73 males and 62 females, aged 18-60 years) with SNHL who sought care at Beijing Chaoyang Hospital, were categorized into mild, moderate, and moderate-to-severe hearing loss groups (45 per group), with 45 normal-hearing controls (23 males and 22 females, aged 20-60 years). Participants completed localization tasks in quiet and noisy environments with SNR levels of 5 dB, 0 dB, -5 dB, and-10 dB. Root mean square error (RMSE) was used to measure localization accuracy. Repeated measures ANOVA assessed the effects of hearing loss and SNR on RMSE, while, Pearson correlation evaluated the relationship between binaural 4-frequency pure-tone average (4fPTA) and RMSE. Multiple linear regression analyzed the predictive role of 4fPTA and age. <b>Results:</b> (1) Two-way repeated measures ANOVA showed that both hearing loss severity and SNR significantly affected RMSE (<i>F</i>=92.67,<i>P</i><0.01;<i>F</i>=430.29,<i>P</i><0.01), with a significant interaction between the two factors(<i>F</i>=92.67,<i>P</i><0.01). (2) RMSE increased with hearing loss severity. At SNRs of 5 dB, 0 dB, and-5 dB, the moderate-to-severe group had significantly higher RMSE than the mild and moderate groups (<i>P</i><0.01). No significant differences were found between mild and moderate groups (<i>P</i>=0.53, 0.57, 0.22). At-10 dB SNR, significant differences were observed across all groups (<i>P</i><0.01). (3) RMSE increased non-linearly as SNR decreased. Mean RMSE values under quiet conditions and at SNRs of 5 dB, 0 dB, -5 dB, and-10 dB were (7.43±5.01)°, (9.80±5.74)°, (11.60±6.22)°, (14.56±7.07)°, and (18.74±8.02)°, respectively. (4) RMSE was significantly positively correlated with binaural 4fPTA (<i>r</i>=0.54-0.58, <i>P</i><0.01). Multiple linear regression analysis indicated that the binaural average 4fPTA significantly predicted RMSE (<i>P</i><0.01), explaining 30.5%-34.1% of RMSE variance. Age did not significantly contribute to RMSE variation. <b>Conclusions:</b> The degree of hearing loss and background noise SNR significantly affect horizontal sound localization in young and middle-aged SNHL patients. RMSE increases with hearing loss severity and decreases with higher SNR. The interaction between hearing loss and SNR is significant, and RMSE correlates with binaural 4fPTA. However, the regression model based on 4fPTA and age explains only part of the RMSE variance, suggesting other contributing factors.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 ","pages":"785-791"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The changes and analysis of the ability of sound localization for patients with unilateral sudden hearing loss during the early period of treatment]. 【单侧突发性听力损失患者治疗初期声音定位能力的变化及分析】。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20240708-00408
W B Wang, J Q Shang, M M Wang, S S Tian, S Liang, Z M Fan, H B Wang, Y Ai
{"title":"[The changes and analysis of the ability of sound localization for patients with unilateral sudden hearing loss during the early period of treatment].","authors":"W B Wang, J Q Shang, M M Wang, S S Tian, S Liang, Z M Fan, H B Wang, Y Ai","doi":"10.3760/cma.j.cn115330-20240708-00408","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240708-00408","url":null,"abstract":"<p><p><b>Objective:</b> To assess the sound localization ability of patients with unilateral sudden hearing loss during the early period of treatment, to explore its changing characteristics and to analyze influencing factors. <b>Methods:</b> A total of 22 patients with unilateral sudden sensorineural hearing loss, with onset within 3 days, who were hospitalized at Shandong Provincial ENT Hospital between January and April 2024, were collected in this study. The cohort included 13 males and 9 females, with a mean age of 36.5 years. Among them, 10 suffered in the right ear and 12 in the left ear. Additionally, 15 healthy individuals (8 males and 7 females, mean age 29.2 years) were selected as controls. Pure tone audiometry and sound localization tests were reviewed on the first day, third day, fifth day of admission; the third week after onset, and the pure tone average and the root-mean-square error(RMSE) were used as indicators, respectively. The improvement of the ability of sound localization and pure tone average were assessed by correlation analyses using SPSS, version 27.0, and multiple regression analysis was employed to explore effects that might influence sound localization ability. <b>Results:</b> The pure tone threshold and sound localization ability on the third week of onset were improved compared with those on the initial three instances(the first, third, and fifth days of admission). 9 of the 22 patients (40.91%, 9/22) presented normal sound localization ability whereas their hearing loss had not recurred yet. The Spearman correlation analysis revealed a significant positive correlation between the improvement of sound localization ability and hearing improvement (<i>r</i>=0.57, <i>P</i><0.001). Meanwhile, multiple regression analysis showed that hearing threshold was a significant factor for sound localization when there was audible frequency. Vice versa, at this circumstance, ages and vertigo were significant factors. <b>Conclusions:</b> For most of the patients with unilateral sudden hearing loss, ability of sound localization improves with the decrease of hearing threshold. Notably, some patients can restore normal levels of sound localization for white noise, even in the presence of hearing loss at certain frequencies, by relying on binaural acoustic cues provided by residual hearing.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 7","pages":"769-775"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nine cases of laryngeal spindle cell squamous cell carcinoma]. [喉梭形细胞鳞癌9例]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20240929-00552
Y Z Liu, Z H Lyu, X L Liu, W W Wu, L Yang, B Li
{"title":"[Nine cases of laryngeal spindle cell squamous cell carcinoma].","authors":"Y Z Liu, Z H Lyu, X L Liu, W W Wu, L Yang, B Li","doi":"10.3760/cma.j.cn115330-20240929-00552","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240929-00552","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 7","pages":"831-834"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Evaluation of reliability and validity of the Chinese version of the Speech, Spatial and Qualities of Hearing Scale]. 《言语、空间和听觉质量量表》中文版信效度评价。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20240630-00390
J Z Wu, J Zhang
{"title":"[Evaluation of reliability and validity of the Chinese version of the Speech, Spatial and Qualities of Hearing Scale].","authors":"J Z Wu, J Zhang","doi":"10.3760/cma.j.cn115330-20240630-00390","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240630-00390","url":null,"abstract":"<p><p><b>Objective:</b> To sinicize the Speech, Spatial and Qualities of Hearing Scale (SSQ) and to assess its reliability and validity based on the Rasch model and Classical Test Theory (CTT). <b>Methods:</b> The acquisition of the Chinese version of the SSQ relies on the systematic translation of the SSQ using the Brislin model. A total of 416 patients who attended the Department of Otorhinolaryngology, Head and Neck Surgery, Chaoyang Hospital, Beijing, between October 2022 and October 2023 were randomly selected using the Chinese version of the SSQ, of which 400 questionnaires were valid, with 281 subjects with hearing impairment [aged 16-92 (59.4±14.4) years, 164 females and 117 males] and 119 subjects with normal hearing [aged 18-72 (39.9±13.6) years, 82 females and 37 males]. The reliability and validity of the Chinese version of the SSQ were assessed by SPSS 24.0 and Winstep 3.72.3 statistical software. <b>Results:</b> Rasch model analysis showed that the Chinese version of the SSQ consisted of a speech perception dimension (14 items), a spatial hearing dimension (17 items), and an auditory quality dimension (18 items), each with unidimensional properties, and the data measured by the scale could be adapted for Rasch model analysis. The Chinese version of the SSQ had reliability indices over 0.8 and separation indices over 2.0 for all three dimensions. The distribution of the difficulty of the questions in the three dimensions was relatively concentrated (the three dimensions of means was: Logit 0.00), and the participants competence was relatively broad (the respective means was: Logit 0.67, Logit-1.71, Logit 0.83). Among them, the item-total correlation coefficients (ITCC) of item 28 and 30 were below 0.7, while ITCC values for the rest were all greater than 0.7. The discriminative validity was good (t=9.604-12.268,<i>P</i><0.01). Exploratory factor analysis showed that the contribution rate of the three principal components was 78.49%, and the loadings of the items on the corresponding common factors were all greater than 0.4. The three rotated common factors were basically consistent with those of the original SSQ in the three dimensions. The Chinese version of the SSQ had a high predictive value for hearing loss (AUC of 0.789, <i>P</i><0.001), with a sensitivity of 61.3% and specificity of 80.1% for predicting hearing loss in case of its mean score <8.5. <b>Conclusion:</b> The Chinese version of the SSQ has favorable reliability and validity, which can serve as a self-assessment tool of hearing ability for people with hearing loss in China in clinical application.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 7","pages":"759-768"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Novel PAX1 mutation identified in autosomal dominant otofaciocervical syndrome 2 with new phenotypes]. 在常染色体显性耳面颈综合征2中发现新的PAX1突变。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20240723-00443
Y Chen, R Yang, N E Lin, Q X Yu, X Chen, T Y Zhang, J Ma
{"title":"[Novel <i>PAX1</i> mutation identified in autosomal dominant otofaciocervical syndrome 2 with new phenotypes].","authors":"Y Chen, R Yang, N E Lin, Q X Yu, X Chen, T Y Zhang, J Ma","doi":"10.3760/cma.j.cn115330-20240723-00443","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240723-00443","url":null,"abstract":"<p><p><b>Objective:</b> To determine the diagnosis of microtia-associated syndrome through genetic testing. <b>Methods:</b> Peripheral venous blood samples were collected from members of a two-generation family with a syndrome associated with ear malformations (3 patients and 1 normal control). Pathogenic mutations were identified using whole exome sequencing analysis, Sanger sequencing validation, and bioinformatics analysis. Based on the genetic diagnosis and a review of the literatures, the patients' clinical phenotypes were thoroughly evaluated to confirm the clinical diagnosis. <b>Results:</b> All three patients carried a novel heterozygous insertion mutation (c.1171_1172insGGCC: p.Pro391fs) in the paired box 1 (<i>PAX1</i>) gene. This mutation showed genotype-phenotype co-segregation within the family and was predicted to be pathogenic. Consequently, the family was diagnosed with autosomal dominant otofaciocervical syndrome 2. The clinical phenotypes of the patients included not only ear malformations and conductive hearing loss but also branchial cleft fistula, preauricular fistula, bilateral facial asymmetry, spinal deformities, and short stature, which were major symptoms of otofaciocervical syndrome 2. Imaging also revealed previously unreported phenotypes, including parotid gland malformation and facial nerve dysplasia. <b>Conclusion:</b> The heterozygous insertion in <i>PAX1</i> (c.1171_1172insGGCC: p.Pro391fs) found in this family causes otomandibular-cervical syndrome type 2 in an autosomal dominant manner, leading to congenital anomalies affecting external and middle ear, craniofacial region, and spine.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 7","pages":"815-823"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sound localization strategies for patients with bilateral cochlear implants]. 双侧人工耳蜗植入患者的声音定位策略。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20240718-00429
J Y Li, N Y Wang
{"title":"[Sound localization strategies for patients with bilateral cochlear implants].","authors":"J Y Li, N Y Wang","doi":"10.3760/cma.j.cn115330-20240718-00429","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240718-00429","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 7","pages":"837-843"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Preliminary analysis of the factors affecting sound localization in patients with unilateral sudden sensorineural hearing loss]. [影响单侧突发性感音神经性听力损失患者声音定位的因素初步分析]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20240702-00398
Y Q Zheng, Y Q Guan, A Q Dai, J M Gong, P F Guan, M Y Xiang, H Z Yu, J F Wu, Y F Wang
{"title":"[Preliminary analysis of the factors affecting sound localization in patients with unilateral sudden sensorineural hearing loss].","authors":"Y Q Zheng, Y Q Guan, A Q Dai, J M Gong, P F Guan, M Y Xiang, H Z Yu, J F Wu, Y F Wang","doi":"10.3760/cma.j.cn115330-20240702-00398","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240702-00398","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the factors influencing sound localization in patients with unilateral sudden sensorineural hearing loss, so as to provide the reference for hearing rehabilitation of patients with unilateral sudden hearing loss. &lt;b&gt;Methods:&lt;/b&gt; This study was a cross-sectional study that retrospectively analyzed the clinical data and audiological examination results of 228 patients with unilateral sudden sensorineural hearing loss(103 males and 125 females; aged from 18 to 80 years, with an average age of 46.2 years; 107 cases in the left ear and 121 cases in the right ear; 8 cases of low-frequency decline type, 42 cases of high-frequency decline type, 92 cases of flat decline type, and 86 cases of total deafness type)at the Eye and ENT Hospital of Fudan University from June 2023 to April 2024. The minimum audible angle (MAA) was calculated by the angle discrimination test of 1000 Hz and 4000 Hz warble tones, which were recorded as MAA&lt;sub&gt;1 000&lt;/sub&gt; and MAA&lt;sub&gt;4 000&lt;/sub&gt; according to the frequency of the given sound stimulus. The root mean square error (RMSE) was calculated by the angle recognition test with daily natural sounds as the stimulus sound. Using SPSS 27.0 statistical software, correlation and multiple regression analysis were used to research the clinical factors affecting the ability of sound localization in patients with unilateral sudden sensorineural hearing loss. &lt;b&gt;Results:&lt;/b&gt; The mean MAA&lt;sub&gt;1 000&lt;/sub&gt;, MAA&lt;sub&gt;4 000&lt;/sub&gt;, RMSE of patients with unilateral sudden deafness were (53.97±29.14)°, (46.34±28.87)° and (30.06±13.64)°, respectively. Univariate analysis of variance revealed that there were significant differences between different classifications of sudden sensorineural hearing loss for sound localization tests (MAA&lt;sub&gt;1 000&lt;/sub&gt;:&lt;i&gt;F&lt;/i&gt;=6.338,&lt;i&gt;P&lt;&lt;/i&gt;0.001,MAA&lt;sub&gt;4 000&lt;/sub&gt;:&lt;i&gt;F&lt;/i&gt;=14.334,&lt;i&gt;P&lt;/i&gt;&lt;0.001,RMSE:&lt;i&gt;F&lt;/i&gt;=49.918,&lt;i&gt;P&lt;&lt;/i&gt;0.001), post-hoc analysis observed that all significant contrasts were included the type of total deafness and low-frequency deafness. Correlation analysis showed the age of subjects in this study was weak positively correlated to the MAA&lt;sub&gt;1 000&lt;/sub&gt; (&lt;i&gt;r&lt;/i&gt;=0.165,&lt;i&gt;P&lt;/i&gt;=0.013), the duration of sudden sensorineural hearing loss was weak negatively related to RMSE (&lt;i&gt;r&lt;/i&gt;=-0.144,&lt;i&gt;P=&lt;/i&gt;0.030), there were significant positive relationships between the threshold of PTA, PTA&lt;sub&gt;1kHz&lt;/sub&gt;, PTA&lt;sub&gt;4kHz&lt;/sub&gt; for the affected side, as well as the binaural PTA difference and sound localization test (MAA&lt;sub&gt;1 000&lt;/sub&gt;,MAA&lt;sub&gt;4 000&lt;/sub&gt;,RMSE) (all &lt;i&gt;P&lt;/i&gt;&lt;0.001). The multiple regression analysis showed the age and the binaural PTA difference for the affected side were the significant factors for the MAA&lt;sub&gt;1 000&lt;/sub&gt; and MAA&lt;sub&gt;4 000&lt;/sub&gt;, the binaural PTA difference was the significant factors for the RMSE. The R&lt;sup&gt;2&lt;/sup&gt; of multivariable linear regression model for MAA&lt;sub&gt;1 000&lt;/sub&gt;, MAA&lt;sub&gt;4 000&lt;/sub&gt; and RMSE results in unilateral ","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 7","pages":"776-784"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Spatial hearing: from mechanisms to clinical applications]. 空间听力:从机制到临床应用。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20241208-00685
L Wei, J Zhang
{"title":"[Spatial hearing: from mechanisms to clinical applications].","authors":"L Wei, J Zhang","doi":"10.3760/cma.j.cn115330-20241208-00685","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20241208-00685","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 7","pages":"852-857"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The study on horizontal sound localization ability in patients with unilateral sensorineural hearing loss]. 单侧感音神经性听力损失患者水平声定位能力的研究
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20240719-00430
Q Q Hao, S Nie, J Zhang
{"title":"[The study on horizontal sound localization ability in patients with unilateral sensorineural hearing loss].","authors":"Q Q Hao, S Nie, J Zhang","doi":"10.3760/cma.j.cn115330-20240719-00430","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240719-00430","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To investigate the factors influencing horizontal sound localization ability in patients with unilateral sensorineural hearing loss (USHL), with the aim of providing evidence-based guidance for clinical rehabilitation. &lt;b&gt;Methods:&lt;/b&gt; This cross-sectional study included 43 patients diagnosed with USHL (22 males, 21 females; age range: 30-60 years, mean age: 46.5 years), recruited from Beijing Chaoyang Hospital, Capital Medical University, between October 2023 and April 2024. A control group of 20 age-matched normal-hearing participants (8 males, 12 females; mean age: 45.5 years) was also enrolled. Data collected included demographic variables, four-frequency pure-tone averages (4fPTA at 500, 1 000, 2 000, and 4 000 Hz) for both ears, and duration of hearing loss. Based on the residual hearing in the affected ear, USHL patients were divided into a group with residual hearing (defined as having at least one frequency threshold ≤65 dBHL) and a group with no detectable hearing (all frequencies &gt;65 dBHL). Furthermore, patients in the residual hearing group were categorized by hearing loss severity into those with moderate hearing loss (35 dBHL ≤4fPTA &lt;50 dBHL) and those with moderate-to-severe hearing loss (4fPTA≥50 dBHL). All participants underwent horizontal sound localization testing using speech stimuli under four listening conditions: quiet, and noise at signal-to-noise ratios (SNRs) of +5 dB, 0 dB, and -5 dB. Localization performance was quantified using root-mean-square error (RMSE), and data were analyzed using two-way ANOVA and Pearson correlation in SPSS 26.0. &lt;b&gt;Results:&lt;/b&gt; Both the degree of hearing loss and background SNR significantly influenced localization accuracy (hearing level: &lt;i&gt;F&lt;/i&gt;=47.59, &lt;i&gt;P&lt;/i&gt;&lt;0.01; SNR: &lt;i&gt;F&lt;/i&gt;=69.79, &lt;i&gt;P&lt;/i&gt;&lt;0.01), with a significant interaction between the two factors (&lt;i&gt;F&lt;/i&gt;=2.81, &lt;i&gt;P&lt;/i&gt;&lt;0.01). In quiet environments, even patients with moderate hearing loss demonstrated significantly poorer localization performance compared to normal-hearing controls (&lt;i&gt;P&lt;/i&gt;&lt;0.01). Among those with residual hearing, localization ability at SNR=+5 dB was not significantly different from that in quiet (&lt;i&gt;P&lt;/i&gt;&gt;0.05), but performance deteriorated significantly at SNR=0 dB (&lt;i&gt;P&lt;/i&gt;&lt;0.001). In contrast, patients without residual hearing exhibited significant deficits even at SNR=+5 dB (&lt;i&gt;P&lt;/i&gt;&lt;0.001). Pearson correlation analysis revealed no significant association between RMSE and sex, age, or duration of hearing loss (all &lt;i&gt;P&lt;/i&gt;&gt;0.05). However, a strong positive correlation was observed between hearing loss severity and RMSE across all noise conditions (&lt;i&gt;r&lt;/i&gt;=0.760-0.800, all &lt;i&gt;P&lt;/i&gt;&lt;0.001), indicating that worse hearing thresholds were associated with poorer localization performance. &lt;b&gt;Conclusions:&lt;/b&gt; Even moderate unilateral sensorineural hearing loss can impair horizontal sound localization, and this deficit is exacerbated by increasing hearing loss severity and background noi","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 7","pages":"800-806"},"PeriodicalIF":0.0,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Guideline for the diagnosis and surgical treatment of adult obstructive sleep apnea (2024)]. [成人阻塞性睡眠呼吸暂停诊断与手术治疗指南(2024)]。
Chinese journal of otorhinolaryngology head and neck surgery Pub Date : 2025-07-07 DOI: 10.3760/cma.j.cn115330-20250308-00133
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引用次数: 0
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