{"title":"[Major challenges in the management of cervical esophagus cancer].","authors":"X M Li","doi":"10.3760/cma.j.cn115330-20260209-00090","DOIUrl":"10.3760/cma.j.cn115330-20260209-00090","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 ","pages":"381-385"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147783070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J L Zuo, Y N Lan, W Sun, Y F Qiao, S J Wang, B Y Guo, J Y Yang, H Zhang, J Li, Y Y Shang
{"title":"[M-Quick SIN in hearing screening: a pilot study in elderly physical examination populations].","authors":"J L Zuo, Y N Lan, W Sun, Y F Qiao, S J Wang, B Y Guo, J Y Yang, H Zhang, J Li, Y Y Shang","doi":"10.3760/cma.j.cn115330-20250704-00354","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20250704-00354","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the practicality of the M-Quick SIN for hearing screening in elderly individuals during physical examinations and to evaluate its consistency with pure-tone audiometry (PTA). <b>Methods:</b> The study is a cross-sectional study, a total of 980 elderly individuals (586 males, 394 females; Age range: 60-90 years old, with an average of 66.4±5.8 years old) who underwent physical examinations at the Peking Union Medical College Hospital physical examination center from February to December 2023, were screened using PTA and M-Quick SIN. We performed statistical analysis using SPSS 27.0, and the practicality of M-Quick SIN was determined using receiver operating characteristic (ROC) curves and the area under the curve (AUC). <b>Results:</b> The signal-to-noise ratio loss (SNR loss) in the poorer ear measured by M-Quick SIN showed a statistically significant gender difference, with males demonstrating greater loss than females (<i>Z</i>=2.859, <i>P</i><0.05), and increased withage and the average hearing threshold across 500, 1 000, 2 000, and 4 000 Hz frequencies (4-frequency pure-tone average, 4fPTA) in the poorer ear. Multiple linear regression analysis showed, age (<i>β</i>=0.163, <i>P</i><0.001) and poorer ear 4fPTA (<i>β</i>=0.729, <i>P</i><0.001) have a significant positive predictive effect on poorer ear M-Quick SIN SNR loss, while gender has no significant effect on poorer ear M-Quick SIN SNR loss (<i>P</i>=0.642). ROC curve analysis demonstrated that the M-Quick SIN signal-to-noise ratio loss in the poorer ear predicted a poorer-ear 4fPTA>35 dBHL with an AUC of 0.89±0.01, and the optimal cut-off value was>11 dB. Concordance between poorer ear M-Quick SIN SNR loss>11 dB and poorer ear 4fPTA>35 dBHL was substantial (<i>Kappa</i>=0.611, <i>P</i><0.001). <b>Conclusions:</b> As a speech-in-noise test, M-Quick SIN can serve as a supplementary screening tool for hearing loss in the elderly. A bilateral M-Quick SIN SNR loss≤11 dB may be considered the pass criterion for hearing screening, demonstrating high practicality and accuracy.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 4","pages":"417-423"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Transoral laser microsurgery for T1b glottic carcinoma: analysis of therapeutic outcomes and prognostic study of anterior commissure staging].","authors":"Y Ling, Q Wang, J S Zhou, Y Li, G K Fan","doi":"10.3760/cma.j.cn115330-20251019-00549","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20251019-00549","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the oncological outcomes of transoral laser microsurgery (TLM) for T1b glottic carcinoma and to investigate the impact of anterior commissure (AC) involvement on prognosis. <b>Methods:</b> This retrospective case series study included 107 patients with T1b glottic carcinoma who underwent TLM at the Department of Otorhinolaryngology, Second Affiliated Hospital of Zhejiang University School of Medicine, from January 1, 2012, to June 30, 2024. The cohort comprised 101 males and 6 females, aged from 43 to 85 years (median age, 64 years), with a follow-up duration of 12.0 to 146.6 months (median follow-up, 34.6 months). Patients were stratified by AC involvement grade (AC0-3: 19, 24, 39, and 25 cases, respectively). The primary endpoints were the 3-year and 5-year local control rate (LCR) and disease-specific survival (DSS). Statistical analysis was performed using SPSS software (version 25.0). <b>Results:</b> Among the 107 patients, the overall 3 year and 5 year LCR were 93.1% and 86.6%, respectively; the corresponding DSS rates were 99.1% and 95.7%. Tumor recurrence occurred in 9 patients, showing an increasing trend with higher AC grades. The 5 year LCR for AC0, AC1, AC2, and AC3 was 94.4%, 95.7%, 87.3%, and 61.3%, respectively. Of the 9 recurrent patients, 7 underwent re-TLM, and 2 died of the disease. No severe complications occurred. Anterior commissure thickness was significantly correlated with tumor recurrence (<i>t</i>=-2.181, <i>P</i>=0.032). Postoperative complications included vocal cord leukoplakia (<i>n</i>=7), vocal cord adhesion (<i>n</i>=6), and persistent granulation tissue (<i>n</i>=4), all managed with secondary surgery. Staged surgery was performed in 10 patients, and ventricular band mucosal flaps were applied in 15 patients. <b>Conclusion:</b> TLM demonstrates favorable oncological efficacy in the treatment of T1b glottic carcinoma. TLM should be used with caution in patients with severe AC involvement. Although LCR tends to decrease with higher AC grades, this trend lacks statistical significance, and the conclusion awaits further validation.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 4","pages":"432-438"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Guideline for diagnosis and treatment of sudden sensorineural hearing loss (2026, interpretation version)].","authors":"","doi":"10.3760/cma.j.cn115330-20260302-00122","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20260302-00122","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 4","pages":"341-370"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J K Xu, C L Cui, Y L Zhang, Y H Xu, L Zhuang, Y D Jin
{"title":"[A case of chronic rhinosinusitis caused by Serratia marcescens infection].","authors":"J K Xu, C L Cui, Y L Zhang, Y H Xu, L Zhuang, Y D Jin","doi":"10.3760/cma.j.cn115330-20251113-00597","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20251113-00597","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 4","pages":"455-456"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Research and application progress of optical coherence tomography in rhinology].","authors":"M R Pan, H J Qiu, L B Liu, Q T Yang","doi":"10.3760/cma.j.cn115330-20250714-00370","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20250714-00370","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 4","pages":"481-487"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Guideline for diagnosis and treatment of sudden sensorineural hearing loss (2026 practical edition)].","authors":"","doi":"10.3760/cma.j.cn115330-20260302-00121","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20260302-00121","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 4","pages":"331-340"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Li, E Tian, X X Yu, Z Y Zhai, J Wang, X X Chen, S L Zhang
{"title":"[A preliminary exploration of vestibular reserve].","authors":"F Li, E Tian, X X Yu, Z Y Zhai, J Wang, X X Chen, S L Zhang","doi":"10.3760/cma.j.cn115330-20251221-00678","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20251221-00678","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 4","pages":"459-467"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F Zhang, Z Wang, X W Zhang, Z Y Wang, X K Chen, Y Li, Y Li, J W Luo, S Y Liu, C M An
{"title":"[A retrospective study on the therapeutic effect of neck dissection in patients with cervical esophageal squamous cell carcinoma].","authors":"F Zhang, Z Wang, X W Zhang, Z Y Wang, X K Chen, Y Li, Y Li, J W Luo, S Y Liu, C M An","doi":"10.3760/cma.j.cn115330-20260213-00094","DOIUrl":"10.3760/cma.j.cn115330-20260213-00094","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the surgical outcomes in cervical esophageal squamous cell carcinoma (CESCC) patients with cervical lymph node metastasis (CLNM). <b>Methods:</b> We performed a retrospective analysis on 180 CESCC patients (141 males, 39 females; with median age of 59 years, ranging in age from 24 to 76) who underwent surgical treatment at the Cancer Hospital, Chinese Academy of Medical Sciences from February 2001 to October 2023. Based on the regions of cervical lymph node metastasis, patients were divided into three groups: non-lymph node metastasis group, central compartment metastasis-only group, and a combined central and lateral cervical metastasis group. We aimed to compare the impact of cervical lymph node metastasis regions and different preoperative intervention regimens on survival outcomes. The 3-year and 5-year overall survival (OS) rates were estimated using the Kaplan-Meier method, and univariate and multivariate Cox regression analyses were performed to identify factors associated with prognosis. <b>Results:</b> Cervical lymph node dissection was performed in 123 patients with CLNM. Among all patients, 54 patients received preoperative chemotherapy, and 19 patients received preoperative chemotherapy combined with immunotherapy. The median OS in the entire cohort was 46 months, with 3-and 5-year OS rates of 58.04% and 42.02%, respectively. Patients without CLNM exhibited significant higher 5-year OS rate than those with CLNM (54.86% <i>vs</i>. 35.69%, χ<sup>2</sup>=7.29, <i>P</i>=0.007). No significant difference in 5-year OS rate was observed between the central neck lymph node metastasis-only group (54 patients) and the combined central and lateral neck lymph node metastasis group (69 patients) (35.98% <i>vs</i>. 35.36%, χ<sup>2</sup>=0.17, <i>P</i>=0.676). Preoperative chemotherapy and chemoimmunotherapy significantly reduced the mortality risk (<i>HR</i>=0.61 and 0.12, respectively; both <i>P</i><0.05). Regarding the 3-year OS rate, there was a significant difference among the chemoimmunotherapy group (90.91%), chemotherapy-only (65.89%) and no-preoperative chemotherapy (49.68%) groups (overall χ<sup>2</sup>=11.22, <i>P</i>=0.004). Compared with patients who did not receive radiotherapy, preoperative and postoperative radiotherapy were not associated with a significant reduction in mortality risk (both <i>P</i>>0.05). <b>Conclusions:</b> After cervical lymph node dissection, the surgical efficacy of lateral CLNM patients resembles that of patients with central CLNM. Preoperative chemoimmunotherapy significantly improves the OS rates of CESCC patients.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 ","pages":"394-402"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y L Su, R Dong, Z G Geng, L Lu, F L Guan, X P Qi, J Du, J M Xue
{"title":"[Clinical analysis of 10 cases of antineutrophil cytoplasmic antibody-associated vasculitis with predominantly nasal symptoms].","authors":"Y L Su, R Dong, Z G Geng, L Lu, F L Guan, X P Qi, J Du, J M Xue","doi":"10.3760/cma.j.cn115330-20251121-00622","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20251121-00622","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the diagnostic and therapeutic characteristics of patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) with predominantly nasal symptoms. <b>Methods:</b> Clinical data of 10 patients (4 males and 6 females, aged 24-73 years) with AAV with predominantly nasal symptoms who were treated in the Second Hospital of Shanxi Medical University from January 2019 to January 2025 were collected and retrospectively analyzed with regard to clinical manifestations, endoscopy, imaging, laboratory examination, pathohistology, treatment and prognosis of the patients. Descriptive statistical methods were used for analysis. <b>Results:</b> Nasal symptoms such as nasal congestion, pus and dry crusts and pulmonary manifestations such as cough and pulmonary nodules were present in all 10 patients; most of them were accompanied by multifocal involvement of the head and neck (9/10) and systemic inflammatory prodromal manifestations such as intermittent fever and polyarticular pain (9/10). Nasal endoscopy showed congestion, erosion, and increased secretion of the nasal mucosa, and in severe cases, perforation of the nasal septum was seen (3/10). Sinus CT showed thickening of nasal and sinus mucosa, bone hyperplasia, and even progressive bone destruction and paranasal sinus granuloma formation (2/10). Laboratory tests showed ANCA positivity in 9 cases and negativity in 1. Six patients were treated with nasal surgery and 5 had postoperative outbreaks. Ten patients were treated with systemic glucocorticoid combined with immunosuppressant or monoclonal antibody after diagnosis, and all of them went into remission. During follow-up, 6 cases relapsed and all 10 cases survived. <b>Conclusions:</b> For patients with refractory nasal symptoms and inflammatory precursor manifestations (combined with other extra-nasal systems), who have poor responses to conventional treatment, AAV should be considered. Early ANCA testing, histopathological examination and multidisciplinary team combined diagnosis and treatment should be performed to improve patient prognosis.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"61 4","pages":"446-452"},"PeriodicalIF":0.0,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147857312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}