Chinese journal of otorhinolaryngology head and neck surgery最新文献

{"title":"[Application status and research progress of portable monitoring in adults].","authors":"H J Yue, L Sun, W B Guo, W B Lei","doi":"10.3760/cma.j.cn115330-20250212-00097","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20250212-00097","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"979-985"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Study on the diagnostic value of fetal magnetic resonance imaging of external ear abnormalities].","authors":"K Y Wang, X L Wang, Y T Liang, B Li","doi":"10.3760/cma.j.cn115330-20241128-00660","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20241128-00660","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the diagnostic value of fetal MRI in external ear abnormalities. <b>Methods:</b> 28 fetuses with suspected ear abnormalities based on ultrasound and MRI in Beijing Obstetrics and Gynecology Hospital, Capital Medical University from August 2019 to February 2024 were enrolled retrospectively. The morphology of fetal auricle and external auditory canal were observed to determine the types of external ear abnormalities. The results of postpartum physical examination were taken as the gold standard, paired <i>χ²</i> test and <i>kappa</i> test were used with SPSS 21.0 software to compare the difference and consistency of fetal MRI and ultrasound in diagnosis of external ear abnormalities. <b>Results:</b> 22 cases (31 ears) of microtia were found, of which 30 ears were detected by MRI (sensitivity 96.8%, specificity 100%, accuracy 98.2%) and 28 ears were detected by ultrasound (sensitivity 87.1%, specificity 96.0%, accuracy 91.1%). The detection rates of the two methods were higher in MRI, but there was no statistically significant difference between MRI and ultrasound in diagnosis of microtia (<i>P</i>=0.688), and the results of the two examinations were consistent (<i>kappa</i>=0.786, <i>P<</i>0.001). 24 ears of external auditory canal atresia were all correctly diagnosed by MRI. However, ultrasound could not detect any external auditory canal atresia. <b>Conclusion:</b> The diagnostic ability of MRI for fetal external ear abnormalities was similar to that of ultrasound, and it showed obvious advantages in the diagnosis of external ear canal atresia.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"911-916"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Research progress on trace elements in childhood allergic rhinitis].","authors":"Q Wang, L Yu, J Chen","doi":"10.3760/cma.j.cn115330-20240920-00535","DOIUrl":"10.3760/cma.j.cn115330-20240920-00535","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"996-1000"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of the safety and associated risk factors of rush immunotherapy in 316 patients with allergic rhinitis].","authors":"M Y Wei, X H Zhu, Y T Xiao, W M Luo","doi":"10.3760/cma.j.cn115330-20241017-00585","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20241017-00585","url":null,"abstract":"<p><p><b>Objective:</b> To assess the safety and to identify risk factors associated with systemic adverse effects (SAEs) during the dose-escalation phase of rush immunotherapy (RIT) in patients with allergic rhinitis (AR). <b>Methods:</b> A retrospective analysis was conducted in 316 house dust mite-allergic patients diagnosed with AR who underwent RIT at the Second Affiliated Hospital of Nanchang University between February 2012 and August 2024, including 206 males and 110 females aging from 5 to 58 years old. The number of patients experiencing SAEs, the frequency of SAE incidents, and the severity grades of SAEs during the dose-escalation phase were analyzed. Associations between SAE occurrence and 19 potential factors, including demographic characteristics, serological parameters, and pulmonary function parameters, were investigated. Data were analyzed using IBM SPSS Statistics version 26.0. <b>Results:</b> Among the 316 patients, 4 358 RIT injections were administered during the dose-escalation phase. SAEs occurred in 45 patients (14.24%, 45/316), accounting for 57 distinct SAE incidents. The SAE incidence rate per injection was 1.31%. Of the 57 SAEs, 34 (59.65%) were Grade Ⅰ, 5 (8.77%) were Grade Ⅱ, and 18 (31.58%) were Grade Ⅲ. No Grade Ⅳ or Ⅴ SAEs were observed. SAE occurrence demonstrated significant associations with: age (<i>Z</i>=-2.73, <i>P</i>=0.006), body mass index (BMI; <i>t</i>=4.08, <i>P</i><0.001), skin prick test reaction intensity (<i>χ²</i>=10.34, <i>P</i>=0.006), eosinophil count (<i>Z</i>=-2.19, <i>P</i>=0.028), eosinophil percentage (<i>Z=</i>-2.59, <i>P</i>=0.010), forced expiratory volume in one second (FEV₁; <i>Z</i>=-2.04, <i>P</i>=0.042), peak expiratory flow (PEF; <i>Z</i>=-2.44, <i>P</i>=0.015). Multivariate logistic regression analysis identified BMI as an independent risk factor for SAEs (<i>OR</i>=0.86; 95%<i>CI</i>: 0.75-0.99; <i>P</i>=0.034). <b>Conclusions:</b> During the RIT dose-escalation phase for house dust mite-allergic AR patients, the incidence of SAEs was approximately 1.31% per injection. SAEs were predominantly mild (Grade Ⅰ), consistent with a favorable overall safety profile. BMI was identified as a statistically significant risk factor for SAE occurrence.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"954-960"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical analysis of transnasal endoscopic optic nerve decompression for traumatic optic neuropathy in preschoolers].","authors":"M Y Chen, K J Zuo","doi":"10.3760/cma.j.cn115330-20240904-00506","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240904-00506","url":null,"abstract":"<p><p><b>Objective:</b> To explore the efficacy and safety of endoscopic optic nerve decompression in preschoolers with traumatic optic neuropathy. <b>Methods:</b> The clinical data of 10 cases (12 eyes) of traumatic optic neuropathy in preschoolers aged 1-6 years (mean 3.6 years) admitted to the First Affiliated Hospital of Sun Yat-sen University from 2015 to 2024 were retrospectively analyzed. The visual acuity changes before and after endoscopic optic nerve decompression were compared, and the surgical complications were observed. Clinical effectiveness was defined as an improvement of at least one level in visual acuity. <b>Results:</b> All patients were followed up for 3 to 60 months, and the clinical effective rate was 10/12. The effective rate of 10 eyes with preoperative no light perception was 8/10. There were 2 eyes with preoperative residual vision: 1 eye with visual acuity of 0.01 and 1 eye with light perception only, and the effective rate was 2/2. The time from injury to surgery was 5 to 112 days, with an average of 44.4 days. After eye trauma, the success rate was 1/1 within 7 days after surgery; for 7 eyes with trauma from 8 to 30 days after surgery, the success rate was 5/7; for 4 eyes with trauma from 31 to 112 days after surgery, the effective rate was 4/4. No intracranial, orbital, or nasal complications occurred during or after surgery in any patient. <b>Conclusions:</b> Endoscopic optic nerve decompression is safe and effective in the treatment of traumatic optic neuropathy in preschoolers aged 1-6 years. Surgery remains clinically beneficial even when performed more than 7 days after injury.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"937-942"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between obstructive sleep apnea-hypopnea syndrome and reflux esophagitis: a cross-sectional study].","authors":"Y F Shi, X J Yang, P Y Zhou, H J Tang, Y H Lyu","doi":"10.3760/cma.j.cn115330-20250109-00025","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20250109-00025","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to evaluate the association between obstructive sleep apnea-hypopnea syndrome (OSAHS) and reflux esophagitis (RE). <b>Methods:</b> This cross-sectional study retrospectively analyzed 218 patients diagnosed with OSAHS by polysomnography (PSG) and who also had undergone gastroscopy at the First People's Hospital of Yunnan Province from January 2021 to December 2021. The cohort comprised 91 males and 127 females, aged from 19 to 78 years (40.7±13.2). Clinical data, PSG parameters, and gastroscopy findings were collected. The prevalence of RE among OSAHS patients was calculated, potential risk factors for RE were evaluated. Differences in PSG parameters between patients with and without RE were analyzed. Statistical analyses were conducted using SPSS 26.0. <b>Results:</b> The prevalence of RE in OSAHS patients was 20.6% (45/218). Males had a significantly higher RE prevalence than females (31.9% <i>vs</i>. 12.6%, χ²=12.02, <i>P</i><0.05). The difference remained significant after adjusting for confounding factors (34.9% <i>vs</i>. 11.1%, χ²=10.08, <i>P</i><0.05). No significant variation in RE prevalence was observed across age groups. However, after adjusting for confounding factors, a significant difference was found between overweight and obese BMI groups (12.5% <i>vs</i>. 29.2%, χ²=4.04, <i>P</i><0.05). When stratified by apnea-hypopnea index (AHI) severity, RE prevalence increased progressively in mild (7.1%), moderate (18.8%), and severe (30.1%) groups, with statistically significant differences (χ²=11.45, <i>P</i><0.05). Positive correlations were found between RE and male sex, AHI, longest apnea time (LAT), and time spent with oxygen saturation below 90% (TS90%) (<i>rs=</i>0.24, 0.18, 0.17, 0.14, respectively, <i>P</i><0.05). Regression analysis showed that identified male sex was the primary independent predictor of RE. Patients with RE exhibited higher AHI, TS90%, and LAT compared to those without RE (<i>P</i><0.05)<b>.</b> <b>Conclusion:</b> This single-center hospital-based study revealed a relatively high prevalence of reflux esophagitis (20.6%) among patients with OSAHS. Male sex was identified as the main independent factor associated with RE. Furthermore, RE prevalence increased with greater AHI, BMI, LAT and TS90%.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"897-902"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Surgical resection of clival Langerhans cell histiocytosis in a child via an oral approach: a case report].","authors":"Y C Chen, X Wang, Y S Teng, J S Wang, H G Pan","doi":"10.3760/cma.j.cn115330-20241008-00562","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20241008-00562","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"967-968"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Interpretation and implications of the phase Ⅲ KEYNOTE-689 trial in head and neck squamous cell carcinoma].","authors":"Z G Huang, Y Zhang","doi":"10.3760/cma.j.cn115330-20250619-00322","DOIUrl":"10.3760/cma.j.cn115330-20250619-00322","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"863-867"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Advances in the application of deep learning in temporal bone CT imaging].","authors":"Y Huang, X Tian, Z Q Gao, G D Feng","doi":"10.3760/cma.j.cn115330-20250219-00110","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20250219-00110","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"986-991"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical and salivary metabolomic characterization of patients with OSA comorbid with LPRD].","authors":"Y L Du, S S Ding, Y Zhao, Y T Qi, S H Sun, T Li, L M Zheng, Y Yan","doi":"10.3760/cma.j.cn115330-20250115-00046","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20250115-00046","url":null,"abstract":"<p><p><b>Objective:</b> To explore the clinical and salivary metabolic component characteristics of patients with OSA combined with LPRD, and to investigate the potential co-morbid mechanisms of LPRD and OSA. <b>Methods:</b> A total of 98 adult patients with OSA (81 males and 17 females) who visited the Department of Otolaryngology of Peking University Third Hospital from March 2024 to May 2024 were consecutively included. The age ranged from 19 to 68 years (mean±standard deviation: 39.44±11.39 years). The severity of OSA was grouped according to the apnea-hypopnea index (AHI) [mild group (29 cases), moderate group (26 cases), and severe group (43 cases)]. Patients with a reflux symptom index score (RSI)>13 points and/or a reflux sign score (RFS)>7 points were considered LPRD positive. Among the 98 OSA patients, 48 had LPRD and 50 did not. All patients were diagnosed with OSA through out of center sleep testing(OCST) or polysomnography (PSG), and general information, laryngoscopic examination images, and RSI scales were collected. The RFS was evaluated based on the laryngoscopic examination results. Saliva samples were collected from both groups for metabolomics analysis. Chi-square test was used for categorical variable comparison, and independent sample t-test or one-way ANOVA analysis of variance was used for continuous variable comparison. <b>Results:</b> Stratified analysis showed that the proportion of male patients in the mild OSA group was significantly lower than that in the moderate or severe OSA groups (58.6%, 92.3%, 93.0%, <i>χ</i>²=16.43, <i>P</i><0.001), and the BMI was significantly lower in the mild OSA group [(25.80±4.41)kg/m², (27.53±3.88)kg/m², (28.99±3.65)kg/m², <i>F</i>=6.91, <i>P</i>=0.002]. There was no statistically significant difference in the prevalence of LPRD among patients with different severity of OSA. The BMI of OSA patients with LPRD was higher than that of patients with OSA alone [(28.65±4.75)kg/m², (26.94±3.16)kg/m², <i>t</i>=-2.07,<i>P</i>=0.041], but there were no statistically significant differences in gender composition, age, AHI, and minimum blood oxygen saturation between the two groups. The metabolomics results of saliva samples from both groups showed significant differences in the levels of tryptophan pathway metabolites. The salivary serotonin metabolite level in patients with LPRD combined with OSA was significantly lower than that in patients with OSA alone (relative abundance 0.12±0.019 vs 0.22±0.046, <i>t</i>=2.04,<i>P</i>=0.045). <b>Conclusion:</b> Patients with OSA combined with LPRD have a greater BMI and significantly lower serotonin, a tryptophan metabolite component of saliva, which may be a potential co-morbidity mechanism between OSA and LPRD.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 8","pages":"890-896"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}