{"title":"[Progress on the mechanisms of olfactory epithelium injury in chronic rhinosinusitis associated olfactory dysfunction].","authors":"L F Y Fan, F Q Chen","doi":"10.3760/cma.j.cn115330-20240430-00250","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240430-00250","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 4","pages":"470-477"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Exploring the criteria for assessing hypoxemia in patients with obstructive sleep apnea from the standpoint of hypertension].","authors":"L L Yu, S Z Zou, Y Y Jia, R Zhang, J R Li","doi":"10.3760/cma.j.cn115330-20241022-00593","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20241022-00593","url":null,"abstract":"<p><p><b>Objective:</b> To determine appropriate cutoff values for evaluating hypoxemia severity in patients with obstructive sleep apnea (OSA). <b>Methods:</b> This cross-sectional study selected data from 1, 781 young patients with obstructive sleep apnea (OSA) who underwent polysomnography in the Department of Otorhinolaryngology Head and Neck Surgery of the Sixth Medical Center of PLA General Hospital from January 2015 to June 2023. The cohort included 1, 604 males and 177 females, with a mean age of (32.6±5.3) years. The relationship between the minimum arterial oxygen saturation (MSaO<sub>2</sub>) and the prevalence of hypertension in this population was investigated. Subjects were categorized into seven groups based on MSaO<sub>2</sub> levels: Group 1 (MSaO<sub>2</sub>≥90%), Group 2 (85%≤MSaO<sub>2</sub><90%), Group 3 (80%≤MSaO<sub>2</sub><85%), Group 4 (75%≤MSaO<sub>2</sub><80%), Group 5 (70%≤MSaO<sub>2</sub><75%), Group 6 (65%≤MSaO<sub>2</sub><70%), and Group 7 (MSaO<sub>2</sub><65%). The prevalence of hypertension in each group was statistically analyzed, and the chi-square test was used to identify significant differences in hypertension prevalence. The diagnostic performance of the new versus traditional grouping methods was evaluated using receiver operating characteristic (ROC) curve analysis. <b>Results:</b> Among the 1, 781 OSA patients, 915 had hypertension. The prevalence of hypertension in Groups 1 to 7 was 27.8%, 42.4%, 52.2%, 54.1%, 59.5%, 70.5%, and 75.4%, respectively. Significant differences in hypertension prevalence were observed between Group 1 and other groups, Group 2 and Groups 5-7, Group 3 and Groups 6-7, and Group 4 and Group 7(χ2=187.94,<i>P</i><0.001). After merging the groups based on MSaO<sub>2</sub> thresholds of≥90%, 90%>MSaO<sub>2</sub>≥85%, 85%>MSaO<sub>2</sub>≥75%, and MSaO<sub>2</sub><75%, the prevalence of hypertension in the new groups was 27.8%, 42.4%, 53.0%, and 71.2%, respectively, with significant differences between adjacent groups(χ2=178.99,<i>P</i><0.001). ROC curve analysis revealed that the area under the curve (AUC) for the new grouping method (0.676) was higher than that for the original grouping method (0.664). <b>Conclusions:</b> As hypoxemia severity increases in OSA, so does the prevalence of comorbid hypertension. Using MSaO<sub>2</sub> cutoff values of 90%, 85%, and 75% to categorize hypoxemia severity appears more appropriate compared to the existing guideline values of 90%, 85%, and 80%.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 4","pages":"441-446"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Comparison between transoral minimally invasive surgery and Sistrunk surgery for the treatment of lingual thyroglossal duct cyst].","authors":"P J Zhang, X F Tian","doi":"10.3760/cma.j.cn115330-20240831-00500","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240831-00500","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the feasibility and efficacy of transoral minimally invasive surgery for the treatment of lingual thyroglossal duct cyst(LTGDC) by comparison with Sistrunk surgery. <b>Methods:</b> The clinical data of 34 patients with LTGDC were analyzed retrospectively at the First Affiliated Hospital of Zhengzhou University from March 2019 to August 2023. Among these patients, comprising 26 males, 8 females, aged from 1 year and 11 months to 76 years old, with a mean age of 31 years old, 22 patients underwent transoral minimally invasive surgery and 12 patients underwent Sistrunk surgery. The operation time, intraoperative blood loss volume, recovery time and follow-up information of the two groups were analyzed. The follow-up period ranged from 12 to 65 months. An independent sample <i>t</i>-test was used to analyze the surgical duration between the two groups, while the Mann-Whitney <i>U</i> test was employed to analyze data on age, cyst size, intraoperative blood loss, and length of hospital stay between the two groups. <b>Results:</b> There were no significant differences in gender, age and size of the cysts between the two groups(all <i>P</i>>0.05). For the transoral minimally invasive group, the mean operation time was (75.5±20.2) minutes, median intraoperative blood loss volume was 5.0(5.0, 10.0)ml and median recovery time was 9.0(8.0, 10.0)days. The data of Sistrunk group were (131.7±16.8) min, 27.5(20.0, 40.0)ml, 11.0(10.0, 15.0)days respectively. There was a statistically significant difference between the two groups(<i>Z</i>=-8.192, -4.539, -3.71, all <i>P</i><0.001). In the transoral group, there were three recurrences, two patients subsequently underwent Sistrunk surgery, while one opted for continuous observation. Additionally, one patient experienced partial loss of epiglottic cartilage.Four patients in the Sistrunk group developed a pharyngeal fistula, but there were no reported recurrences. <b>Conclusions:</b> Compared to Sistrunk surgery, transoral surgery for lingual thyroglossal duct cyst provides several benefits, such as reduced complication rates, accelerated recovery, and the absence of neck scarring.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 4","pages":"435-440"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Tian, J Q Guo, Z Q Guo, J Y Chen, Z H Zhou, S Y Shi, X X Yu, W D Xu, S Zhou, X B Gao, J Wang, S L Zhang
{"title":"[A preliminary study on the effects of vestibular migraine, Meniere's disease and comorbidities on emotional status and cognitive function].","authors":"E Tian, J Q Guo, Z Q Guo, J Y Chen, Z H Zhou, S Y Shi, X X Yu, W D Xu, S Zhou, X B Gao, J Wang, S L Zhang","doi":"10.3760/cma.j.cn115330-20240829-00498","DOIUrl":"https://doi.org/10.3760/cma.j.cn115330-20240829-00498","url":null,"abstract":"<p><p><b>Objective:</b> This study aims to investigate the differences in emotional status and cognitive function among patients with vestibular migraine (VM), Meniere's disease (MD), and their comorbidity (VMMD), and to analyze key factors influencing cognitive function. <b>Methods:</b> This cross-sectional study included 96 outpatients (32 males, 64 females, aged 21-73 years) from the Department of Otorhinolaryngology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, between December 2022 and December 2023. The study population consisted of 31 VM patients (VM group), 36 MD patients (MD group), and 29 VMMD patients (VMMD group), along with 32 healthy controls (16 males, 16 females, aged 19-74 years). Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA), while emotional status and somatization symptoms were evaluated through the Generalized Anxiety Disorder scale, Patient Health Questionnaire Depression scale, Symptom Checklist-90, and the Self-rating Somatization Symptom scale. Multiple linear regression analysis was conducted to explore the influence of different variables on cognitive function. <b>Results:</b> The total MoCA score in the VMMD group (26.0 [24.5, 28.0]) was significantly lower than that in the control group (28.0 [27.0, 29.0]) and the MD group (28.0 [26.0, 30.0]) (<i>P</i>=0.006). VMMD patients exhibited significant impairments in specific cognitive domains, including visuospatial/executive function, delayed recall, and orientation (<i>P</i><0.05). Patients with VM, MD, and VMMD showed higher rates of anxiety, depression, and somatization symptoms compared to the control group (<i>P</i><0.05), with the VMMD group experiencing the most severe emotional distress. Multiple linear regression analysis identified education level and vestibular disease type as key factors affecting cognitive function, with a university-level education predicting higher MoCA scores (<i>P</i><0.001), while VMMD was associated with cognitive decline (<i>P</i><0.01). <b>Conclusions:</b> Patients with VM and MD, particularly those with comorbid VMMD, exhibit significant emotional distress. Cognitive impairments are present in VM and VMMD patients, affecting different cognitive domains. These factors should be comprehensively considered in clinical assessments to develop more effective treatment strategies.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 4","pages":"394-402"},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J C Wu, B Ye, Y L Shen, H X Hu, Z H Wang, Z H Shi, C Fan, X W Miao, Y N Liu, M L Xiang
{"title":"[Transoral robotic surgery with single-port robot system for tongue base cancer].","authors":"J C Wu, B Ye, Y L Shen, H X Hu, Z H Wang, Z H Shi, C Fan, X W Miao, Y N Liu, M L Xiang","doi":"10.3760/cma.j.cn115330-20250104-00009","DOIUrl":"10.3760/cma.j.cn115330-20250104-00009","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 ","pages":"351-354"},"PeriodicalIF":0.0,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Guideline for diagnosis and treatment of chronic rhinosinusitis (2024)].","authors":"","doi":"10.3760/cma.j.cn115330-20250116-00051","DOIUrl":"10.3760/cma.j.cn115330-20250116-00051","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 ","pages":"221-249"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143731886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y L Zhao, X J Cao, D M Zhang, C F Jiang, W Q Wang, P X Wu
{"title":"[Symptoms and impact on quality of life of patients with Ménière's disease].","authors":"Y L Zhao, X J Cao, D M Zhang, C F Jiang, W Q Wang, P X Wu","doi":"10.3760/cma.j.cn115330-20240624-00370","DOIUrl":"10.3760/cma.j.cn115330-20240624-00370","url":null,"abstract":"<p><p><b>Objective:</b> To explore the symptoms of Ménière's disease patients and their impact on quality of life. <b>Methods:</b> A cross-sectional study was conducted, consecutively enrolling patients of Ménière's disease who visited the Otolaryngology Clinic at the Eye & ENT Hospital of Fudan University from October 2014 to December 2022. The Chinese version of the Ménière's Disease Outcomes Questionnaire (MDOQ) and a Ménière's disease-specific symptom checklist were utilized for assessment. SPSS 25.0 software was employed to perform multiple linear regression analysis to determine the impact of Ménière's disease symptoms on patients' quality of life. <b>Results:</b> A total of 790 patients with a definitive diagnosis of Ménière's disease who met the inclusion and exclusion criteria were analyzed. The cohort comprised 418 males and 372 females, with a mean age of (54.8±13.1) years and a diagnosis duration ranging from 0 to 72 months, with a median of 3 months. The total score of the Chinese MDOQ was 61.0±12.0. The symptomatic presentations of the enrolled patients included hearing changes, tinnitus, aural fullness, drop attacks, vertigo episodes, visual instability, dizziness, and headache. Multiple linear regression analysis revealed that age, tinnitus, aural fullness, frequency of drop attacks, visual instability, dizziness, and headache were significant factors affecting the quality of life in Ménière's disease patients (<i>F</i>=145.50, <i>P</i><0.05). <b>Conclusions:</b> The quality of life in Ménière's disease patients requires improvement. Attention to the specific symptoms of Ménière's disease and their impact on patients' quality of life, along with targeted symptom interventions based on these findings, will be a focal point in future disease management.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 3","pages":"305-312"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Analysis of current research on recurrent sudden sensorineural hearing loss].","authors":"J L Zhang, L S Yu, X Ma","doi":"10.3760/cma.j.cn115330-20240401-00191","DOIUrl":"10.3760/cma.j.cn115330-20240401-00191","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 3","pages":"360-365"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y Q Xie, X D Cha, F Z Li, S L Wang, Z Y Xu, W W Ren, H H Liu, J Wu
{"title":"[Olfactory dysfunction, aging, and neurodegenerative diseases].","authors":"Y Q Xie, X D Cha, F Z Li, S L Wang, Z Y Xu, W W Ren, H H Liu, J Wu","doi":"10.3760/cma.j.cn115330-20240331-00185","DOIUrl":"10.3760/cma.j.cn115330-20240331-00185","url":null,"abstract":"","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 3","pages":"366-370"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Xu, L Tao, Y Wang, F Y Liang, C Z Xu, L L Deng, X Zou, X Lu, X M Huang, P Han
{"title":"[Multicenter retrospective study of transoral robotic surgery for supraglottic laryngeal cancer].","authors":"K Xu, L Tao, Y Wang, F Y Liang, C Z Xu, L L Deng, X Zou, X Lu, X M Huang, P Han","doi":"10.3760/cma.j.cn115330-20240807-00466","DOIUrl":"10.3760/cma.j.cn115330-20240807-00466","url":null,"abstract":"<p><p><b>Objective:</b> To explore the safety, effectiveness, and short-term outcomes of transoral robotic surgery (TORS) for supraglottic laryngeal cancer. <b>Methods:</b> A retrospective analysis was conducted on patients with supraglottic laryngeal cancer who underwent TORS at Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Eye Ear Nose and Throat Hospital of Fudan University, and the First Affiliated Hospital of China Medical University between January 2018 and April 2024. Data on operative time, intraoperative blood loss, postoperative hospital stay, perioperative tracheostomy, nasogastric feeding, complications, and short-term follow-up were analyzed. Statistical analysis was performed using Python. <b>Results:</b> A total of 27 patients with supraglottic laryngeal cancer were included from the four centers, including 24 males and 3 females, with a median age of 66 (65, 68) years [<i>M</i>(<i>Q</i><sub>1</sub>, <i>Q</i><sub>3</sub>), same below]. There were 26 cases of squamous cell carcinoma and 1 case of adenoid cystic carcinoma.The TNM staging included T1 in 10 cases (37.04%), T2 in 13 cases (48.15%), and T3 in 4 cases (14.81%); N0 in 14 cases (51.85%), N1 in 7 cases (25.93%), and N2 in 6 cases (22.22%). The Da Vinci Si system was used in 23 cases, and the Da Vinci Xi in 4 cases. The robotic surgical time was 53 (30, 58) min. Concurrent neck dissection was performed in 25 cases, neoadjuvant therapy was given preoperatively in 8 cases (29.63%), and postoperative radiotherapy was administered in 13 cases (48.15%). Tracheostomy was performed in 11 cases (40.74%). Nasogastric tube placement was required in 23 cases (85.19%), with a median duration of 16 (12, 21) days. The postoperative hospital stay was 9.19±4.07 days. The median follow-up time was 12 (3, 30) months. Local recurrence occurred in 2 cases. The 3-year overall survival rate was 100%, and the 3-year disease-free survival rate was 94.1%. <b>Conclusion:</b> With appropriate patient selection, TORS for supraglottic laryngeal cancer demonstrates satisfactory short-term outcomes, thereby offering advantages in safety, efficacy, and minimal invasiveness, which can be considered a new treatment option for this condition.</p>","PeriodicalId":23987,"journal":{"name":"Chinese journal of otorhinolaryngology head and neck surgery","volume":"60 ","pages":"266-271"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}