中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240513-00267
F H Wang, N Yang, J Wang, M T Wei, X G Wang, C Yang, Y L Zhang
{"title":"[Interaction of obesity and dyslipidemia on the risk of hypertension].","authors":"F H Wang, N Yang, J Wang, M T Wei, X G Wang, C Yang, Y L Zhang","doi":"10.3760/cma.j.cn112338-20240513-00267","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240513-00267","url":null,"abstract":"<p><p><b>Objective:</b> To understand the interaction effect of general obesity, central obesity, and dyslipidemia on the risk of hypertension to provide scientific evidence for the early prevention and control of hypertension. <b>Methods:</b> From 2019 to 2023, 10 of the 16 districts in Tianjin were selected as project sites. A community and a natural village were selected as monitoring sites in each project site using a multi-stage cluster random sampling method. A questionnaire, physical, and biochemical examination were conducted on permanent residents aged 35-75 who had lived in the surveillance sites for more than half a year. The chi-square test univariate and multivariate logistic regression were used for statistical analysis. The multiplicative and additive models were used to calculate the interaction between general obesity and dyslipidemia, as well as central obesity and dyslipidemia, respectively. <b>Results:</b> A total of 177 160 subjects were included in the study, with an age of (56.44±8.62) years old. There were 29 535 (16.67%) patients with general obesity, 67 338 (38.01%) patients with central obesity, 64 906 (36.64%) patients with dyslipidemia, and 90 266 (50.95%) patients with hypertension. Multiplication interaction analysis results showed that, after adjusting for gender, age, culture level, marriage status, drinking, smoking, and diabetes, the multiplicative interactions between general obesity and dyslipidemia, and central obesity and dyslipidemia on hypertension were statistically significant (all <i>P</i><0.001), and the adjusted <i>OR</i> and 95%<i>CI</i> were 2.57 (2.47-2.68) and 2.14 (2.08-2.20), respectively. The results of the additive interaction analysis demonstrated that after adjusting for relevant variables, the relative excess risk of interaction (<i>RERI</i>), the attributable proportion of interaction (<i>API</i>), and the synergy index (<i>SI</i>) of the interaction between generalized obesity and dyslipidemia were 0.48 (95%<i>CI</i>: 0.33-0.63), 0.15 (95%<i>CI</i>: 0.11-0.19), and 1.27 (95%<i>CI</i>: 1.18-1.36), respectively; the <i>RERI</i>, <i>API</i>, and <i>SI</i> of the interaction between central obesity and dyslipidemia were 0.37 (95%<i>CI</i>: 0.28-0.46), 0.13 (95%<i>CI</i>: 0.10-0.16), and 1.25 (95%<i>CI</i>: 1.18-1.32), respectively. <b>Conclusions:</b> There might be multiplicative and additive interactions between general obesity, central obesity, and dyslipidemia on the risk of hypertension. Simultaneous control of BMI, waist circumference, and blood lipid levels may effectively reduce the risk of hypertension.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1658-1665"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240605-00331
X Li, Y B Zhao, Q Ren, H Jia, T Chen, Q Wu, W H Chang
{"title":"[Awareness, willingness, and status of using HIV pre-exposure prophylaxis among men who have sex with men in Shaanxi Province].","authors":"X Li, Y B Zhao, Q Ren, H Jia, T Chen, Q Wu, W H Chang","doi":"10.3760/cma.j.cn112338-20240605-00331","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240605-00331","url":null,"abstract":"<p><p><b>Objective:</b> To analyze awareness, willingness, the status of using, and related factors of HIV pre-exposure prophylaxis (PrEP) in men who have sex with men (MSM) in Shaanxi Province to provide a reference for the next step of HIV prevention and control strategy. <b>Methods:</b> Using a cross-sectional study design from March to May 2022, with the assistance of MSM social organizations in Xi'an, relying on the network platform and MSM Social organizations, a convenient sampling method was used to recruit MSM with an estimated sample size of 900. The inclusion criteria were male aged ≥18, having had same-sex sexual intercourse in the last twelve months, HIV-negative or unknown status of infection. An electronic questionnaire was made with the help of questionnaire-star and an anonymous self-administered questionnaire was used to collect information on socio-demographic characteristics, sexual behavior, awareness and using of PrEP, <i>etc</i>. A logistic regression model was used to analyze related factors of PrEP awareness and use in MSM. SPSS 25.0 software was used for statistical analysis. <b>Results:</b> Among 981 MSM subjects, 76.55% (751/981) had heard of PrEP, and 42.51% (417/981) were aware of PrEP. Among those who knew about PrEP, 74.34% (310/417) had homosexual sexual activity in the last six months, 99.03% (307/310) were willing to use PrEP, and 40.97% (127/310) were using PrEP. The multivariate logistic regression analysis model results showed that nationality (other ethnic groups:a<i>OR</i>=4.48,95%<i>CI</i>:1.28-15.68),education level (high school or technical secondary school: a<i>OR</i>=3.01,95%<i>CI</i>:1.49-6.07; universities or colleges: a<i>OR</i>=2.86,95%<i>CI</i>:1.47-5.57; master degree: a<i>OR</i>=5.10,95%<i>CI</i>:2.37-10.98), monthly income 5 000-10 000 yuan (a<i>OR</i>=1.70,95%<i>CI</i>: 1.00-2.88), tested for HIV in the past 12 months (a<i>OR</i>=1.87,95%<i>CI</i>:1.34-2.61) were related factors of PrEP knowledge awareness. Singlehood (a<i>OR</i>=0.46,95%<i>CI</i>:0.26-0.81) and consulted professionals about PrEP (a<i>OR</i>=9.56,95%<i>CI</i>:4.58-19.96) were related factors of PrEP use. <b>Conclusions:</b> The proportion of willingness to use PrEP was higher among MSM in Shaanxi Province, but the awareness rate and utilization rate of MSM for PrEP were low. The cognition of PrEP should be further improved to promote the correct use of PrEP among MSM.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1679-1684"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240602-00322
R H Tang, Y C Yang, R H Ye, L F Xiang, Y R Gong, S J Yang, Q B Zhou, X Duan, S Duan, D Shan
{"title":"[Epidemic characteristics of HIV-infected people among Chinese and Burmese in Dehong Dai and Jingpo Autonomous Prefecture of Yunnan Province, 2000-2023].","authors":"R H Tang, Y C Yang, R H Ye, L F Xiang, Y R Gong, S J Yang, Q B Zhou, X Duan, S Duan, D Shan","doi":"10.3760/cma.j.cn112338-20240602-00322","DOIUrl":"10.3760/cma.j.cn112338-20240602-00322","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the epidemic characteristics and trends of newly reported HIV-infected people among Chinese and Burmese in Dehong Dai and Jingpo Autonomous Prefecture (Dehong Prefecture) of Yunnan Province, China, from 2000 to 2023, and provide evidence for formµlating AIDS prevention and control measures for the Burmese living in Dehong. <b>Methods:</b> The data were obtained from the Chinese Disease Control and Prevention Information System. The distribution of HIV-infected people with different population characteristics was analyzed, and the Joinpoint regression model was used to analyze the temporal trend of crude detection rate in different genders, ethnicities, and ages. <b>Results:</b> From 2000 to 2023, 24 989 newly HIV infections were reported in Dehong Prefecture, of which 14 594 (58.4%) were Chinese and 10 395 (41.6%) were Burmese. Compared with Chinese, Burmese women (32.9%, 3 416/10 395), those aged 20-29 (40.9%, 4 248/10 395), and Jingpo people (26.7%, 2 773/10 395) accounted for a higher proportion. The new diagnosis rate of Chinese nationals increased from 1.0/10 000 in 2000 to 15.4/10 000 in 2004, and then showed a downward trend, falling to 1.2/10 000 in 2023. Among them, compared with other age groups, Dai and other ethnic groups and women, the new diagnosis rate among 20-49 age group, Jingpo and men were relatively higher, at 1.7/10 000, 2.3/10 000 and 1.3/10 000 respectively. Regarding the method of detection, the Chinese HIV-infected people were mainly detected by key population testing (35.7%), while the Burmese HIV-infected people by key population testing (28.9%) and physical examination for entry-exit personnel (25.3%). The transmission routes of both nationalities were mainly heterosexual transmission, but compared with Chinese HIV-infected persons, the proportion of Burmese infected persons through non-marital non-commercial transmission was relatively higher (66.4% <i>vs</i>. 60.6%). The proportion of Chinese nationals with a first CD4<sup>+</sup>T lymphocyte (CD4) counts of <200 cells/µl (28.9%) was higher than that of Burmese nationals (19.8%). <b>Conclusions:</b> The rising trend of HIV infection among Chinese and Burmese people in Dehong Prefecture from 2000 to 2023 slowed down. The new diagnosis rate was higher in the 20-49 age group, Jingpo and men. Compared with Burmese HIV-infected people, the proportion of Chinese HIV-infected people with first CD4 counts <200 cells/µl was relatively higher. Comprehensive interventions should be further carried out for Myanmar nationals, and efforts should be made to expand testing for Chinese nationals.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1633-1638"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240618-00359
Y Liang, Y K Xu, P Y Fan, Y G Nie, J Geng, J C Shi, G L Zhang, D Y Zhao
{"title":"[Spatial-temporal distribution of newly reported HIV/AIDS cases in Henan Province, 1995-2020].","authors":"Y Liang, Y K Xu, P Y Fan, Y G Nie, J Geng, J C Shi, G L Zhang, D Y Zhao","doi":"10.3760/cma.j.cn112338-20240618-00359","DOIUrl":"10.3760/cma.j.cn112338-20240618-00359","url":null,"abstract":"<p><p><b>Objective:</b> To identify the spatial clustering and its temporal trends among newly reported HIV/AIDS cases in Henan Province during 1995-2020, and to provide evidence for strategies on prevention and control of the disease. <b>Methods:</b> Information about newly reported HIV/AIDS cases in Henan between 1995 and 2020 were obtained from China Information System for Disease Control and Prevention and to describe their demographic characteristics, spatial autocorrelation and changing trends. This program was conducted at county level, using the ArcGIS 10.2. <b>Results:</b> A total of 96 528 HIV/AIDS cases with complete current address information in counties (districts) were newly reported during 1995-2020 in Henan, and the spatial autocorrelation analysis showed that Global Moran's <i>I</i> index was 0.249, <i>Z<sub>G</sub></i> value of the Global Getis-Ord <i>G</i> coefficient was 6.472 (all <i>P</i><0.001), indicating that there was a high clustered positive spatial autocorrelation of HIV/AIDS. The newly reported HIV/AIDS cases from 1995 to 2000, 2001 to 2005, 2006 to 2010, 2011 to 2015, and 2016 to 2020 in Henan Province all exhibited high values of global spatial clustering. Their Moran's <i>I</i> indices were 0.197, 0.103, 0.491, 0.411 and 0.383, respectively. The <i>Z<sub>G</sub></i> values of the Global Getis-Ord <i>G</i> coefficient were 4.580, 3.386, 10.246, 8.378 and 8.093, respectively. All of global spatial correlation were statistically significant (all <i>P</i><0.001). The results of local spatial autocorrelation analysis showed that newly reported HIV/AIDS cases in Henan Province had high-high clustering areas at each time stage mentioned above. The number of high-high clustering counties/districts gradually increased from 6 in 2001-2005 to 21 in 2016-2020, spreading from Zhumadian City and Zhoukou City in southeast Henan to Nanyang City in southwest Henan, Zhengzhou City and its surrounding counties/districts in central Henan. <b>Conclusions:</b> In Henan Province, an increasing trend of clusters appeared on HIV epidemic among newly reported HIV/AIDS cases from 1995 to 2020, and high-high clustering areas gradually expanded from Zhumadian City and Zhoukou City to Nanyang City, Zhengzhou City and its surrounding counties/districts, indicating that it is necessary to strengthen the AIDS prevention and control programs in these areas in Henan.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1685-1692"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20241009-00620
X P Song, S Cong, J Fan, N Wang, W J Wang, L W Fang
{"title":"[Prevalence and influencing factors of severe respiratory infections in childhood among residents of China, 2019-2020].","authors":"X P Song, S Cong, J Fan, N Wang, W J Wang, L W Fang","doi":"10.3760/cma.j.cn112338-20241009-00620","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241009-00620","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the exposure level and changes in severe respiratory infection among Chinese residents aged ≥40 years in China and to provide essential data for preventing and controlling chronic respiratory diseases. <b>Methods:</b> The data came from chronic obstructive pulmonary disease surveillance of Chinese residents in 2014-2015 and 2019-2020. The surveillance covers 31 provinces (autonomous regions and municipalities) in China. A multi-stage stratified cluster random sampling method was used to select permanent residents aged ≥40 years. Relevant information about exposure to severe respiratory infections during childhood was collected through investigation. Rigorous complex sampling and weighted analysis were applied to estimate the exposure rate of severe respiratory infections among children with different characteristics among residents aged ≥40 years in China from 2019 to 2020. Additionally, changes in severe respiratory infections during childhood were analyzed over 2014-2015 and 2019-2020. <b>Results:</b> In 2019-2020, the exposure rate of severe respiratory infection before 18 for residents aged ≥40 years in China was 21.58‰ (95%<i>CI</i>: 17.57‰-25.59‰). The exposure rate of severe respiratory infection before the age of 14 was 19.40‰ (95%<i>CI</i>:15.25‰-23.55‰), the difference in the exposure rate between men and women was not statistically significant (both <i>P</i>>0.05), and the exposure rate of urban residents is higher than that of rural residents. The results of multivariate logistic regression analysis showed that in western rural areas, factors including being born by cesarean section, exposure to secondhand smoke before age 14 years old, and a family history of chronic respiratory diseases were associated with severe respiratory infections in childhood. Compared with 2014-2015, the proportion of residents aged 40 and older in China hospitalized for pneumonia or bronchitis before 14 from 2019 to 2020 was slightly lower than five years prior. <b>Conclusions:</b> Among residents in China aged ≥40 years, 21.58‰ experienced severe respiratory infection exposure during childhood, varying exposure levels across different demographic groups. The burden of chronic respiratory diseases in adulthood cannot be ignored. Efforts should be made to expand the coverage of planned immunization and to focus on early-life interventions during childhood to reduce the incidence of severe respiratory infections.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1617-1625"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240626-00379
S Y Song, Z Y Wu, D J Y Sun, C Q Yu, J Lyu, L M Li, Y J Pang
{"title":"[Recent advances in organ-system-specific biological age].","authors":"S Y Song, Z Y Wu, D J Y Sun, C Q Yu, J Lyu, L M Li, Y J Pang","doi":"10.3760/cma.j.cn112338-20240626-00379","DOIUrl":"10.3760/cma.j.cn112338-20240626-00379","url":null,"abstract":"<p><p>Biological age (BA) is a marker to accurately assess aging, facilitating the prediction of age-related diseases and promoting healthy aging. In recent years, first- and second-generation organ-system-specific BA has been developed using chronological age (CA) or aging-related outcomes (mortality) as training phenotypes and data from questionnaires, physical examinations, clinical biochemistry, imaging, and multi-omics to investigate the specificity of organ systems aging. Here, we review the methodologies for constructing BA, current efforts to assess organ system-specific BA, and related genome-wide association studies (GWAS). Previous studies predominantly used the first-generation BA method, using CA as training phenotypes. Organ-system-specific BA can accurately predict the disease risk of corresponding organ systems. We propose the development of organ system-specific BA through second-generation BA models and conducting GWAS and Mendelian randomization studies to explore organ system-specific aging processes, which will provide a theoretical foundation for the clinical application of organ system-specific BA.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1751-1760"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240531-00319
S Cheng, L Gao, S Si, Y Wang, T Song, X Y Hao, L Li
{"title":"[Survey on diarrhea symptoms and diarrhea vaccination willingness of residents in Tianjin].","authors":"S Cheng, L Gao, S Si, Y Wang, T Song, X Y Hao, L Li","doi":"10.3760/cma.j.cn112338-20240531-00319","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240531-00319","url":null,"abstract":"<p><p><b>Objective:</b> To understand the symptoms of diarrhea of residents in Tianjin and their willingness to vaccinate, to provide reference for health education, prevention and control of infectious diarrhea. <b>Methods:</b> Cross-sectional study design was adopted. From September to December 2023, a questionnaire survey was conducted among some residents as subjects in Nankai District, Beichen District, Baodi District and Binhai Area of Tianjin by multistage stratified cluster random sampling,to collect information such as sociodemographic characteristics, diarrhea symptoms and vaccination intention. According to the formula <i>n</i>=[<i>u</i><sup>2</sup><i><sub>α</sub>π</i>(1 -<i>π</i>)]/<i>δ</i><sup>2</sup>, the estimated sample size was 3 458 cases. The logistic regression model was used to analyze the factors related to the willingness of the respondents to receive diarrhea vaccination. The software SPSS 24.0 was used for statistical analysis. <b>Results:</b> A total of 3 808 subjects were investigated, with the male-to-female ratio as 1∶1.11 (1 806∶2 002), the age was (42.48±21.59) years old, and the education level of middle school or below accounted for 50.84% (1 936/3 808). The incidence rate of diarrhea was 18.28% (696/3 808), and 48.84% (1 860/3 808) were willing to be vaccinated with diarrhea vaccine. The results of multivariate logistic regression analysis showed that the age was 15-59 years old and ≥60 years old (a<i>OR</i>=2.31, 95%<i>CI</i>:1.80-2.96; a<i>OR</i>=1.66, 95%<i>CI</i>:1.38-2.00), lived in Binhai Area (a<i>OR</i>=2.09, 95%<i>CI</i>:1.62-2.71), and those who knew that community health service centers can provide the vaccination (a<i>OR</i>=1.61,95%<i>CI</i>:1.34-1.92), those who walked from the address to the community health service center were less than 15 minutes (a<i>OR</i>=1.54, 95%<i>CI</i>:1.28-1.85), those who often travel or on business (a<i>OR</i>=1.36, 95%<i>CI</i>:1.07-1.73), and those who actively obtained health care information related to diarrhea prevention when going abroad (a<i>OR</i>=1.69,95%<i>CI</i>:1.43-1.98) were more willing to be vaccinated against diarrhea. <b>Conclusions:</b> The incidence of diarrhea symptoms of residents was slightly higher in Tianjin, but they were less willing to be vaccinated against diarrhea. People who often go outside and go abroad were more willing to be vaccinated against diarrhea. It is suggested that the popular science propaganda and health education of diarrhea vaccine should be effectively carried out by using network platform in community.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1666-1671"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240617-00355
H J Li, J Y Bai, M H Yu, X Y Dong, T L Ning, J J Zhu, Y Zhang
{"title":"[Analysis of human papillomavirus infection status and related factors among men who have sex with men in Tianjin].","authors":"H J Li, J Y Bai, M H Yu, X Y Dong, T L Ning, J J Zhu, Y Zhang","doi":"10.3760/cma.j.cn112338-20240617-00355","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240617-00355","url":null,"abstract":"<p><p><b>Objective:</b> The status quo and related factors of human papillomavirus (HPV) infection in multiple parts of men who have sex with men (MSM) in Tianjin were analyzed. <b>Methods:</b> Using the cross-sectional survey method, a total of 600 MSM were recruited in Tianjin from September to December 2023, including 200 (18-26 years old), 300 (27-45 years old), and 100 (≥46 years old) stratificaed by age group. Questionnaire survey was used to collect knowledge and behavioral information related to demography and STD prevention and treatment. Exfoliated cells from genital, perianal and oral cavity were collected for HPV typing detection. Logistic regression model was used to analyze the related factors of HPV infection. <b>Results:</b> The infection rate of HPV was 53.67% (322/600) in MSM, with high-risk type as 41.17% (247/600), low-risk type as 27.17% (163/600). The infection rate of HPV in both multiple and single types was 26.83% (161/600).The infection rates of genotypes covered by nine-valent HPV vaccine, quadrivalent HPV vaccine and bivalent HPV vaccine were 36.83% (221/600), 25.17% (151/600) and 9.50% (57/600), respectively.The infection rates of genital HPV, high-risk or low-risk types were 24.67% (148/600), 16.67% (100/600) and 11.00% (66/600), respectively. The infection rates of perianal HPV, high-risk or low-risk types were 42.00% (252/600), 30.17% (181/600) and 20.50% (123/600), respectively. The infection rates of oral HPV high-risk and low-risk types were 3.17% (19/600), 2.33% (14/600) and 1.17% (7/600), respectively. Divorce or widowhood (a<i>OR</i>=2.38, 95%<i>CI</i>: 1.26-4.50), history of homosexual anal intercourse in the past 6 months (a<i>OR</i>=2.28, 95%<i>CI</i>: 1.00-5.50), and use of dependent drugs (including new psychoactive substances) (a<i>OR</i>=1.62, 95%<i>C</i>I: 1.02-2.58) were risk factors for genital HPV infection. College degree/university degree or above (a<i>OR</i>=0.36, 95%<i>CI</i>: 0.16-0.81) was a protective factor for perianal HPV infection, and a history of drug dependence (a<i>OR</i>=1.85, 95%<i>CI</i>: 1.19-2.88) was a risk factor. <b>Conclusions:</b> MSM in Tianjin was a high-risk group for HPV infection, and the HPV infection in the perianal area was more severe than in the genital area and oral area.Marital status, education level, history of homosexual anal sex in the past 6 months, and history of drug dependence were related factors of HPV infection among MSM.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1693-1699"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240617-00353
X Y Pang, J G Yu, X Yin, Z X Sun, X Liu, J Li, Y L Wu, Q Zhao, Y G Jiang, G M Zhao, N Wang, Q W Jiang
{"title":"[Study on the association of diet pattern with chronic obstructive pulmonary disease in population aged 40 years and above in Songjiang District, Shanghai].","authors":"X Y Pang, J G Yu, X Yin, Z X Sun, X Liu, J Li, Y L Wu, Q Zhao, Y G Jiang, G M Zhao, N Wang, Q W Jiang","doi":"10.3760/cma.j.cn112338-20240617-00353","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240617-00353","url":null,"abstract":"<p><p><b>Objective:</b> To explore the incidence of chronic obstructive pulmonary disease (COPD) in a cohort aged 40 years and above in Songjiang District, Shanghai, and to analyze the association of Mediterranean diet pattern and dietary approaches in stopping hypertension pattern (DASH) with the risk of developing COPD. <b>Methods:</b> Based on a natural population cohort in Songjiang District, Shanghai, 27 474 adults aged 40 years and above who did not have COPD at baseline were enrolled in the study. The Cox proportional risk regression model was used to analyze the association of baseline Mediterranean diet pattern score and DASH score with the risk of COPD, and the hazard ratio (<i>HR</i>) of the risk and its 95%<i>CI</i> were calculated. Restricted cubic spline was used to analyze the nonlinear association between the two diet scores and the risk of COPD. Stratified analyses were performed according to gender, age, smoking status, etcetera. Sensitivity analyses were conducted by censoring cases diagnosed within one year after the baseline survey or people with a history of malignant tumor disease. <b>Results:</b> As of June 30, 2023, after a median follow-up time of 6.21 years, there were 1 089 (4.0%) new COPD cases with an incidence density of 64.00 per 10 000 person-years. After adjusting for relevant confounders, in the Mediterranean tertile subgroups under diet pattern score, the risk of developing COPD could be reduced by approximately 14% in the intermediate scoring group (<i>HR</i>=0.86, 95%<i>CI</i>: 0.75-0.99) and 15% in the highest scoring group (<i>HR</i>=0.85, 95%<i>CI</i>: 0.72-0.99) compared to the lowest scoring group. The association remained after censoring cases diagnosed within one year of the baseline survey (<i>HR</i>=0.82, 95%<i>CI</i>: 0.70-0.95; <i>HR</i>=0.82, 95%<i>CI</i>: 0.68-0.97) or censoring people with a history of malignant tumor disease (<i>HR</i>=0.84, 95%<i>CI</i>: 0.73-0.97; <i>HR</i>=0.84, 95%<i>CI</i>: 0.71-0.99). No statistical association was found between the DASH score and the risk of COPD. <b>Conclusions:</b> The Mediterranean diet pattern was associated with a lower risk of COPD. Increasing the intake of vegetables, fruits, legumes, and whole grains and decreasing the intake of red meat and others can reduce the risk of COPD. No association was found between the DASH dietary pattern and the risk of COPD in this community population.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1649-1657"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华流行病学杂志Pub Date : 2024-12-10DOI: 10.3760/cma.j.cn112338-20240818-00508
J H Si, F Gao
{"title":"[Infodemiology: past, present and future].","authors":"J H Si, F Gao","doi":"10.3760/cma.j.cn112338-20240818-00508","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240818-00508","url":null,"abstract":"<p><p>The internet era has brought a dual impact on epidemiological research: on one hand, it has expanded the breadth and depth of public health surveillance, enriching the formulation of strategies for early warning for public health emergencies and infectious disease outbreaks, disease prevention, and health promotion through vast medical information resources. On the other hand, it has triggered the issue of \"infodemic\", wherein the rapid spread of misinformation disrupts public perception, weakens the effectiveness of public health responses, and adds complexity to the management of public health emergencies. This paper focuses on representative research areas of infodemiology, for example, infodemic caused by inforus, and explores its future development trends and potential challenges with the aim to deepen infodemiology research and optimize public health practice.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"45 12","pages":"1715-1719"},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}