中华流行病学杂志最新文献

{"title":"[Analysis on adverse treatment outcome of rifampicin-resistant tuberculosis patients and influencing factors in 9 provinces in China, 2017-2021].","authors":"H J Sun, X Q Liu, W Su, T Li, Y L Zhao, W Chen","doi":"10.3760/cma.j.cn112338-20240702-00394","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240702-00394","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the incidence of adverse treatment outcome of rifampicin-resistant tuberculosis (RR-TB) patients and influencing factors in 9 provinces in China. <b>Methods:</b> The information about the basic characteristics, diagnosis and treatment of RR-TB patients registered from January 1, 2017 to December 31, 2021 in 9 provinces (Beijing, Jilin, Shanghai, Jiangsu, Zhejiang, Hubei, Henan, Yunnan and Guizhou) were collected from the tuberculosis information management sub-system of China Disease Control and Prevention Information System for a descriptive analysis, and the influencing factors of adverse treatment outcome were identified by binary logistic regression analysis. <b>Results:</b> In 18 204 RR-TB patients in this study a total of 6 852 had adverse treatment outcomes (37.64%). Treatment failure occurred in 1 031 patients, 1 272 patients died, 2 284 patients were lost to follow-up, and 2 265 patients were not evaluated. The results of multivariate logistic regression analysis showed that being man (a<i>OR</i>=1.54, 95%<i>CI</i>: 1.43-1.66), age ≥65 years (a<i>OR</i>=2.42, 95%<i>CI</i>: 2.20-2.67), being from other ethnic groups (a<i>OR</i>=1.18, 95%<i>CI</i>: 1.03-1.35), being farmer (a<i>OR</i>=1.22, 95%<i>CI</i>: 1.13-1.32), being retired with honours or being retired (a<i>OR</i>=1.16, 95%<i>CI</i>: 1.00-1.35) and being floating population (a<i>OR</i>=1.23, 95%<i>CI</i>: 1.13-1.34), re-treatment (a<i>OR</i>=1.33, 95%<i>CI</i>: 1.24-1.42), long-term treatment therapy (a<i>OR</i>=3.26, 95%<i>CI</i>: 2.52-4.23), living in central provinces (a<i>OR</i>=2.76, 95%<i>CI</i>: 2.55-2.99), living in western provinces (a<i>OR</i>=2.31, 95%<i>CI</i>: 2.08-2.57) were the influencing factors for adverse treatment outcome of RR-TB. <b>Conclusions:</b> The incidence of adverse outcomes in RR-TB patients in 9 provinces in China was higher from 2017 to 2021. There were many influencing factors associated with adverse treatment outcome in RR-TB patients, especially the area specific factors. The national tuberculosis control program should strengthen the follow-up and treatment management of RR-TB in men, the elderly, floating population, people in central and western provinces and other key groups, actively promote the short-term treatment program and improve the allocation of medical resources to reduce the influencing for adverse treatment outcomes in RR-TB patient.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"188-195"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between dietary choline intake trajectories and cognitive function in middle-aged and older population].","authors":"Y B Liu, W W Du, Q Y Cao, H J Wang, C Su, Y N He, J G Ji, J Li, X F Jia","doi":"10.3760/cma.j.cn112338-20240906-00559","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240906-00559","url":null,"abstract":"<p><p><b>Objective:</b> To identify the trajectories of dietary choline intake in middle-aged and older population, and to analyze its longitudinal association with cognitive function. <b>Methods:</b> Subjects aged 55 to 79 years with at least two rounds of completed population economics, lifestyle, disease history, cognitive function, dietary assessments and physical measurements in 1997-2018 and those with at least three rounds of dietary measures in 1991-2015 were selected from the China Health and Nutrition Survey. Dietary survey was conducted using three consecutive 24-hour dietary recalls combined with a weighing inventory at the household level. Cognitive assessment was performed using part of the Telephone Interview for Cognitive Status Scale. Group-based univariate trajectory modeling was used to identify trajectory of choline intake, and three-level linear mixed-effects models or three-level logistic mixed-effects models was employed to analyze the relationship between trajectory groups and cognitive function. Subgroup analyses were conducted by gender and age at baseline. <b>Results:</b> Four trajectories of dietary choline intake were identified in the whole population, named as low-intake-stable group (61.0%), medium-intake-stable group (23.9%), medium-intake-slowly-declined group (11.2%), and high-intake-stable group (3.9%). Three trajectories were identified for each subgroup. Low-intake-stable group accounted for more than 60% in total population as well as each subgroup, especially in women and 55-59 years group. After adjusting for covariates, global cognitive scores were 0.54 (95%<i>CI</i>: 0.26-0.82), 0.77 (95%<i>CI</i>: 0.36-1.18), and 0.85 (95%<i>CI</i>: 0.21-1.48) points higher in medium-intake-stable, medium-intake- slowly-declined and high-intake-stable groups in the whole population, respectively, compared with the low-intake-stable group. The likelihoods of cognitive decline were 18.4% (<i>OR</i>=0.816,95%<i>CI</i>: 0.709-0.939), 17.6% (<i>OR</i>=0.824, 95%<i>CI</i>: 0.680-0.998), 24.4% (<i>OR</i>=0.756, 95%<i>CI</i>: 0.589-0.970) and 22.4% (<i>OR</i>=0.776,95%<i>CI</i>: 0.623-0.968) lower in medium-intake-stable group of dietary choline in the whole population, medium-intake-stable group in males, medium-intake-slightly-increased group in females and medium-intake-slowly-increased group in 55-59 years at baseline than in low-intake-stable group, respectively. <b>Conclusions:</b> Dietary choline intake is generally lower in the Chinese population aged 55-79 years. Long-term lower choline intake has a negative impact on cognitive function in middle-aged and older adults and may increase the risk of cognitive decline. The increment in the consumption of choline-enriched foods should be recommended.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"210-217"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Development of an evaluation indicator system for access to cancer screening services: a Delphi study].","authors":"X Wang, A Y Mao, X Y Zhou, P Dong, Y J Li, S Y Cai, Y J Wu, H Y Huang, G X Liu, W H Xu, J M Qin, W Q Chen, J F Shi","doi":"10.3760/cma.j.cn112338-20240622-00367","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240622-00367","url":null,"abstract":"<p><p><b>Objective:</b> To present an evaluation indicator system for access to cancer screening services. <b>Methods:</b> The evaluation indicator pool was constructed through a scoping review. The theoretical framework was constructed based on the multi-source indicators, and the qualitative expert consultation method was employed to form the initial version of the three-level evaluation indicator system. Delphi expert consultation method was conducted in two rounds to evaluate the relevance, importance, and availability of the proposed evaluation indicator system. The expert positive coefficient, authority coefficient, coordination degree of expert opinions, and concentration of expert opinions were subjected to analysis. Subsequently, the three-level evaluation indicator system for access to cancer screening services was adjusted and determined based on the boundary value method and the open opinions of experts. Finally, the combination weight method was employed to determine the weight. <b>Results:</b> The initial version of the indicator system comprised 3 primary (first-level) indicators, 11 secondary (second-level) indicators, and 46 tertiary (third-level) indicators. Delphi expert consultation was conducted for the initial version, and 17 experts ultimately completed it, exhibiting a positive coefficient of 100% and an authority coefficient of 0.87. In comparison to the initial round of consultation, Kendall's W coefficient ranges (0.15-0.43, all <i>P</i><0.05) of relevance, importance, and availability scores for each tertiary indicator in the second round exhibited an improvement. The analysis of the importance dimension indicates that expert opinions are also more concentrated, as evidenced by an increase of 8.5% and 7.0% in the proportion of the tertiary indicators with an arithmetic mean above 8 and a full mark ratio above 0.5, respectively. The final evaluation indicator system comprises three primary indicators, with the weights of structure evaluation, process evaluation, and outcome evaluation being 0.338, 0.378, and 0.285, respectively. It also comprises 11 secondary indicators and 45 tertiary indicators. <b>Conclusions:</b> The evaluation indicator system developed in this article can be an effective evaluation tool for quantitative comparison of access to cancer screening services across different populations, cancer types, and before and after intervention. Furthermore, it is recommended that the system undergo continuous optimization concerning its application.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"307-315"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevalence of common chronic diseases and related factors in HIV-infected persons in Henan Province, 2023].","authors":"Z Y Chen, Q X Zhao, X Yang, M Deng, S X Zhao, C L Liu, M J Hou, Z H Zhang, Q Li, Y Sun","doi":"10.3760/cma.j.cn112338-20240626-00375","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240626-00375","url":null,"abstract":"<p><p><b>Objective:</b> To understand the prevalence and related factors of three common chronic diseases, hyperlipidemia, hypertension and diabetes in HIV-infected persons. <b>Methods:</b> As of December 2023, HIV-infected persons >15 years old who are receiving antiviral therapy (ART) and follow-up in Henan Province were selected as the study objects. Questionnaires, physical examinations, and blood samples were collected to collect demographic information, ART, body weight, blood lipids, blood pressure, and blood sugar of HIV-infected persons. The logistic regression model was used to analyze the related factors of hyperlipidemia, hypertension and diabetes. <b>Results:</b> Among 4 023 HIV-infected patients, the prevalence rates of hyperlipidemia, hypertension, and diabetes were 64.47% (2 594/4 023), 16.80% (676/4 023), and 10.54% (424/4 023), respectively. Multivariate analysis showed that hyperlipidemia was positively associated with ≥40 years of age, overweight and obesity, two nucleoside reverse transcriptase inhibitors (NRTIs) + proteasome inhibitors (PIs) regimen and two NRTIs+ integrase inhibitor regimen, and negatively associated with low body weight. Hypertension was positively correlated with the age group ≥40 years old, family history of cardiovascular and cerebrovascular diseases, overweight and obesity, ART time ≥0.5 years, and negatively correlated with low body weight. Diabetes was positively associated with age group ≥40 years, family history of cardiovascular and cerebrovascular disease, overweight and obesity, and negatively associated with the use of two NRTIs+PIs treatment regimens. <b>Conclusions:</b> In 2023, the prevalence of hyperlipidemia, hypertension, and diabetes among HIV-infected people in Henan Province was relatively high, and the risk of common chronic diseases among those ≥40 years old, overweight and obese, and those with a family history of cardiovascular and cerebrovascular diseases was also relatively high. It is recommended to strengthen the prevention and management of common chronic diseases among HIV-infected people.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"258-263"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A survey on the cognition of mpox expertise among relevant clinicians in China].","authors":"Z W Chen, W Q Zhu, Y L Wu, S Q Liang, X L Yue, J Li, J H Zhang, X D Gong","doi":"10.3760/cma.j.cn112338-20240719-00439","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240719-00439","url":null,"abstract":"<p><p><b>Objective:</b> To investigate and evaluate the correct cognition and influencing factors of mpox expertise among relevant Chinese clinicians and to provide a reference for prevention and control. <b>Methods:</b> A cross-sectional survey was conducted among clinicians in relevant departments using a structured questionnaire compiled by ourselves through a non-random network recruitment method. The content includes demography, clinical specialties, and characteristics of medical institutions, and 37 questions to evaluate the professional cognition of mpox etiology, clinical characteristics, transmission, prevention, and control. Using the modified Bloom's cutoff point to determine the correct answer is greater than or equal to 26 entitled correct cognition. A logistic regression model was used to analyze the factors influencing the correct cognition rate. <b>Results:</b> A total of 4 332 clinicians in 23 provinces (autonomous regions, municipality) in China were investigated by online questionnaires and 4 276 effective questionnaires were collected, with an effective rate of 98.71%. The mean age of the respondents was (39.46±9.54) years old, 61.18% were female. The overall correct cognition rate of mpox expertise was 62.04% (95%<i>CI</i>: 60.59%-63.50%), the correct cognition rates of mpox etiology, clinical characteristics, transmission, prevention and control were 48.25% (95%<i>CI</i>: 46.68%-49.82%), 78.66% (95%<i>CI</i>: 77.38%-79.95%), 68.56% (95%<i>CI</i>: 67.10%-70.02%), respectively. Multivariate logistic regression analysis showed that the relevant factors affecting the overall correct cognition of mpox expertise among Chinese clinicians included gender (female: <i>OR</i>=1.54, 95%<i>CI</i>: 1.31-1.80), region (eastern region: <i>OR</i>=1.46, 95%<i>CI</i>: 1.18-1.79; midwestern region: <i>OR</i>=1.24, 95%<i>CI</i>: 1.04-1.49), professional title (deputy senior: <i>OR</i>=1.43, 95%<i>CI</i>:1.16-1.76; senior: <i>OR</i>=1.72, 95%<i>CI</i>:1.30-2.28), the clinical field (the clinical fields of dermatology and venereal diseases: <i>OR</i>=1.78, 95%<i>CI</i>: 1.42-2.23). <b>Conclusions:</b> The overall correct cognition rate of mpox expertise among relevant Chinese clinicians was low. It was essential to conduct mpox knowledge training for clinicians in males, northeast regions, junior professional title and the clinical fields other than dermatology and venereal diseases to improve their correct cognition rates and epidemic prevention and control ability.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"239-244"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Epidemiological characteristics of hand, foot and mouth disease among people aged 6 and over in Guangzhou, 2010-2023].","authors":"S Y Zhong, H Wang, Q Zeng, Q L Wu, L Luo, X Zhang, Z B Zhang","doi":"10.3760/cma.j.cn112338-20240729-00465","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240729-00465","url":null,"abstract":"<p><p><b>Objective:</b> The purpose of this study was to analyze the epidemiological characteristics of hand, foot, and mouth disease (HFMD) among individuals aged 6 years and above in Guangzhou from 2010 to 2023, with the intention that a scientific basis be provided for effective prevention and control measures in older age groups. <b>Methods:</b> Data on HFMD incidence among individuals aged 6 years and above in Guangzhou from 2010 to 2023 were collected and analyzed. Descriptive epidemiological methods were used to analyze the distributions and pathogen components of HFMD cases in Guangzhou residents aged 6 years and above. Spatial autocorrelation analysis and Getis-Ord <i>Gi</i>* analysis were conducted to identify the spatial clustering patterns of HFMD at the street town level. <b>Results:</b> From 2010 to 2023, the gender ratio of HFMD cases in persons aged 6 and above was 1.49∶1 in Guangzhou. The average annual incidence rate of HFMD among individuals aged 6 years and above in Guangzhou was 25.75 per 100 000. Furthermore, the reported incidence rate indicated an increased tendency. The annual incidence showed a bimodal distribution, with the main peak occurring from May to July and the secondary peak from September to October. HFMD incidence rates vary by townships, with hotspots clustered in urban and urban-rural regions. The dominant pathogen shifts from year to year. Enterovirus 71 (EV71) was the prevalent strain in 2010, followed by other enteroviruses and Coxsackievirus (CV)-A16 from 2011 to 2016. Since 2017, CV-A6 has steadily become the major pathogen. <b>Conclusions:</b> The incidence of HFMD cases among individuals aged 6 years and above in Guangzhou increased generally from 2010 to 2023, with hotspots localized in urban and urban-rural areas. The pathogen composition altered dramatically, with the proportion of EV71 dropping overall, while CV-A6 eventually became the dominating strain. Therefore, it is imperative to focus on the prevention and control of HFMD in this age group, especially by strengthening measures in areas with high prevalence.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"196-203"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between social support and subjective and objective cognitive functions among middle-aged and elderly population in Pingyin County, Jinan City].","authors":"X Li, Q Wang, C Y Fu, Z X Wang, L Y Zhang, X Y Zhang, D S Zhu","doi":"10.3760/cma.j.cn112338-20240812-00496","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240812-00496","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the association between social support and subjective and objective cognitive functions among the middle-aged and elderly population in Pingyin County, Jinan City, Shandong Province. <b>Methods:</b> Employing a multi-stage cluster random sampling method, a cross-sectional study was conducted in 2023 by selecting people aged 45-70 years from seven villages in three towns within Pingyin County, Jinan City, as survey respondents. Social Support Rating Scale (SSRS), Subjective Cognitive Decline-Questionnaire 9 (SCD-Q9) and Montreal Cognitive Assessment-Basic (MoCA-B) were used to assess the social support and cognitive status of interviewees, and a self-developed questionnaire was used to collect other basic information. Pearson correlation analysis, multiple linear regression and multifactorial logistic regression were used to explore the relationship between social support and subjective and objective cognitive functions. <b>Results:</b> A total of 1 891 subjects were finally included in the study, with 45.52±6.99 for the SSRS total score, an abnormal rate of 43.68% (826/1 891) for the SCD-Q9 score and an abnormal rate of 60.02% (1 135/1 891) for the MoCA-B score. The SSRS total score, subjective support score, objective support score and support utilization score were negatively correlated with SCD-Q9 scores and positively correlated with MoCA-B scores (all <i>P</i><0.05). An increase in SSRS total score (<i>β</i>=-0.034, 95%<i>CI</i>: -0.051--0.017, <i>P</i><0.001) and objective support score (<i>β</i>=-0.074, 95%<i>CI</i>: -0.121--0.027, <i>P</i>=0.002) can lower SCD-Q9 scores. Compared to those who had only 1 source of financial support or help with practical problems when experiencing an acute situation, those with 2-4 (<i>OR</i>=0.53, 95%<i>CI</i>: 0.34-0.82), 5 (<i>OR</i>=0.46, 95%<i>CI</i>: 0.27-0.79), or 6-7 (<i>OR</i>=0.42, 95%<i>CI</i>: 0.22-0.81) sources of help were more likely to have normal SCD-Q9 scores. Compared to individuals with ≤2 close friends who provided support and help, those with 3-5 (<i>OR</i>=0.67, 95%<i>CI</i>: 0.50-0.91) or ≥6 friends (<i>OR</i>=0.72, 95%<i>CI</i>: 0.54-0.97) were more likely to have normal MoCA-B scores. Moreover, compared to individuals who never participated in group activities, those who actively participated (<i>OR</i>=0.59, 95%<i>CI</i>: 0.42-0.81) were more likely to have normal MoCA-B scores. <b>Conclusions:</b> Social support has protective effects on subjective and objective cognitive functions, and various social support conditions have different protective effects on subjective and objective cognitive functions among middle-aged and older people. Improving social support conditions for middle-aged and elderly individuals may delay the process of cognitive decline.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"218-225"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Latent-class analysis of intimate partner violence and HIV high risk behaviors among college students in Zhuhai].","authors":"Y H Lin, Y Zhou, Y F Xie, J B Li, X X Tan, K H Lin, Y Yan, H B Jiang","doi":"10.3760/cma.j.cn112338-20240617-00354","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240617-00354","url":null,"abstract":"<p><p><b>Objective:</b> To explore the latent-classes of HIV high risk behaviors among college students, and the association between experiences of intimate partner violence (IPV) and HIV high risk behaviors, to provide evidence for reducing the HIV high risk behaviors among them. <b>Methods:</b> A cross-sectional study was conducted from October to December 2019 among university students from six higher education institutions in Zhuhai City, using a multi-stage cluster sampling method, with an estimated sample size of 1 318. The study included participants who self-reported being in a romantic relationship and having sexual experience within the past year. Data on sociodemographic characteristics, IPV experiences, and HIV high risk behaviors were collected. Latent-class analysis was performed on HIV high risk behaviors, and chi-squared tests and multivariable logistic regression were used to analyze the associations between IPV experiences and different latent classes of HIV high risk behaviors. <b>Results:</b> The effective response rate for the survey was 95.4% (12 235/12 821). 1 382 college students from Zhuhai were included as participants in the study, with 19.4% (268/1 382) self-reporting having experienced IPV. Latent-class analysis of HIV high risk behaviors classified the participants into three latent groups: low-risk group (78.1%, 1 079/1 382), multiple sexual partners/alcohol use before sex group (15.8%, 219/1 382), and high-risk group (6.1%, 84/1 382). Multivariable logistic regression analysis showed that students who had experienced psychological violence were more likely to be in the group that had multiple sexual partners/alcohol use before sex (a<i>OR</i>=2.51, 95%<i>CI</i>:1.48-4.27). Those who had experienced IPV (a<i>OR</i>=5.74, 95%<i>CI</i>:3.45-9.55), physical violence (a<i>OR</i>=9.26, 95%<i>CI:</i> 5.24-16.35), sexual violence (a<i>OR</i>=8.46, 95%<i>CI</i>:4.93-14.52), or psychological violence (a<i>OR</i>=15.99, 95%<i>CI</i>:8.64-29.57) were more likely to be in the high-risk group. Students who experienced two (a<i>OR</i>=9.37, 95%<i>CI</i>:3.55-24.71) or three types of IPV (a<i>OR</i>=50.09, 95%<i>CI</i>: 21.06-119.14) were more likely to be in the high-risk group compared to those with no IPV experiences. <b>Conclusions:</b> HIV high risk behaviors among college students in Zhuhai exhibited heterogeneity across different latent groups, and these groups have different associations with IPV experiences. Universities should tailor targeted HIV/AIDS education and prevention strategies based on the characteristics of each latent group to reduce HIV high risk behaviors among college students.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"245-251"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Development of a pre-processing workflow for real world data derived from multicenter clinical laboratories].","authors":"C Liu, X X Peng, S Y Cai, Y L Liu, C Zhang, F Hu","doi":"10.3760/cma.j.cn112338-20240620-00364","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240620-00364","url":null,"abstract":"<p><p><b>Objective:</b> To develop a pre-processing workflow of real world data (RWD) derived from multicenter clinical laboratories so that the level of data standardization can be improved, and subsequently to produce more robust real world evidence (RWE). <b>Methods:</b> Purpose sampling was used to invite senior experts with experience in clinical research utilizing RWD, covering the fields of clinical laboratory, epidemiology, biostatistics, and clinical medicine. In-depth, semi-structured individual interviews were conducted and thematic analysis was used to analyze the collected data. <b>Results:</b> The in-depth interviews were completed in 16 experts. The experts unanimously agreed that pre-processing RWD derived from multicenter clinical laboratories is necessary prior to its application in research. Based on experts' insights, a comprehensive pre-processing workflow for RWD was constructed, comprising six key steps: ①developing a variable list based on research questions and distributing it to each clinical laboratory; ②conducting an initial quality assessment of RWD based on existing quality control results in clinical laboratories; ③cleaning the data; ④determining whether RWD (including categorical and continuous variables) is heterogeneity among different clinical laboratories; ⑤exploring potential sources of heterogeneity;⑥pre-processing RWD based on identified causes contributing to heterogeneity. <b>Conclusion:</b> The pre-processing workflow of RWD was established, to provide a methodological reference for controlling systematic errors in RWD derived from multicenter clinical laboratories, thereby enhancing the validity of RWE.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"296-306"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevalence and associates of hyperuricemia in middle- and older-aged populations of islands and mountainous areas in Taizhou City of Zhejiang Province].","authors":"Y H Gao, T T Wang, T L Chen, Y L Xie, Y T Wang, S L Wang, L Y Wang, H J Lin, N He","doi":"10.3760/cma.j.cn112338-20240819-00510","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240819-00510","url":null,"abstract":"<p><p><b>Objective:</b> To determine the prevalence and associates of hyperuricemia (HUA) among the middle- and older-aged population of the island and mountainous areas in Taizhou City of Zhejiang Province. <b>Methods:</b> A cross-sectional study was conducted on individuals aged 45 and above in the island and mountainous area of Taizhou City. The study included questionnaires, physical examinations, and laboratory tests. Data were primarily collected on sociodemographic characteristics, chronic disease history, lifestyle factors, waist circumference, blood pressure, and serum uric acid levels. The association between hyperuricemia and these factors was analyzed by logistic regression. <b>Results:</b> A total of 971 individuals were included in the study, comprising 468 from island and 503 from mountainous area. The prevalence of hyperuricemia was 17.9%, with a significantly higher prevalence in the island area (25.6%) compared to the mountainous area (10.7%). Stratified by gender and age, differences in the prevalence of hyperuricemia between island and mountainous areas were observed in males aged 55 to 64, females aged 45 to 54, 55 to 64, 75 and above (all <i>P</i><0.05). Multiple logistic regression analysis showed that high intake of sea food (>3 times/week) was positively associated with hyperuricemia (<i>OR</i>=2.10, 95%<i>CI</i>:1.33-3.34). Furthermore, separate regionally stratified logistic regression analyses showed that in the island area, male gender (<i>OR</i>=3.15, 95%<i>CI</i>:1.78-5.66), central obesity (<i>OR</i>=2.38, 95%<i>CI</i>:1.46-3.93), and hypertriglyceridemia (<i>OR</i>=2.00, 95%<i>CI</i>:1.22-3.30) were positively correlated with hyperuricemia (all <i>P</i><0.05). In the mountainous area, the age group of 65 and above (<i>OR</i>=3.50, 95%<i>CI</i>:1.09-12.50), male (<i>OR</i>=6.79, 95%<i>CI</i>:2.87-17.81), those employed in enterprises and institutions (<i>OR</i>=6.57, 95%<i>CI</i>:1.92-23.73) and hypertension (<i>OR</i>=3.68, 95%<i>CI</i>:1.66-8.87) were positively correlated with hyperuricemia (all <i>P</i><0.05). <b>Conclusions:</b> The prevalence of hyperuricemia among the middle- and older-aged population in the island of Taizhou City is significantly higher than that in the mountainous areas. Targeted comprehensive behavioral interventions such as routine screening of chronic diseases, low-fat diet, alcohol control, reduced seafood intake, enhanced exercise, weight management, and blood pressure control are warranted.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 2","pages":"226-231"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}