中华流行病学杂志最新文献

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[Epidemiological characteristics and influencing factors of diabetes and pre-diabetes among adult residents in Hainan Province]. [海南省成年居民糖尿病及前驱糖尿病流行病学特征及影响因素]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240821-00516
J Jiang, C F Xiong, D W Sun, Y Liu, H Y Wu, X R Wang, X H Wang, T T Ou, X Zhou, S Z Meng, S K Chen, K L Wang, L Zhong, B He
{"title":"[Epidemiological characteristics and influencing factors of diabetes and pre-diabetes among adult residents in Hainan Province].","authors":"J Jiang, C F Xiong, D W Sun, Y Liu, H Y Wu, X R Wang, X H Wang, T T Ou, X Zhou, S Z Meng, S K Chen, K L Wang, L Zhong, B He","doi":"10.3760/cma.j.cn112338-20240821-00516","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240821-00516","url":null,"abstract":"<p><p><b>Objective:</b> To describe epidemiological characteristics and their influencing factors of diabetes and pre-diabetes among adult residents in Hainan Province and provide a theoretical basis to develop epidemic prevention and control strategies for diabetes. <b>Methods:</b> This study used a two-stage unequal proportion cluster sampling method, and 32 857 subjects (≥18 years old) were collected from 24 cities/counties/districts in Hainan Province. All the subjects were investigated with questionnaires, physical examination, and laboratory tests from January to June 2023. The <i>χ</i><sup>2</sup> and Mantel-Haenszel trend <i>χ</i><sup>2</sup> tests were used to analyze the data. Multivariate logistic regression was used to analyze the factors influencing diabetes and pre-diabetes. SPSS 23.0 software was used to analyze the data. <b>Results:</b> The crude prevalence of diabetes and pre-diabetes in adult residents of Hainan Province were 18.1% and 22.8%, while the weighted rates were 13.7% and 20.7%, respectively. The results of multivariate logistic regression analysis showed that: aging (30-39 years old: <i>OR</i>=2.65, 95%<i>CI</i>: 2.06-3.41; 40-49 years old: <i>OR</i>=5.64, 95%<i>CI</i>: 4.40-7.24; 50- 59 years old: <i>OR</i>=9.88, 95%<i>CI</i>: 7.71-12.67; 60-69 years old: <i>OR</i>=18.34, 95%<i>CI</i>: 14.28-23.55; 70-79 years old: <i>OR</i>=21.30, 95%<i>CI</i>: 16.41-27.65; 80 years old and above: <i>OR</i>=24.13, 95%<i>CI</i>: 17.94-32.46), nationality (Li minority group: <i>OR</i>=1.50, 95%<i>CI</i>: 1.38-1.63; other ethnic groups: <i>OR</i>=1.53, 95%<i>CI</i>: 1.20-1.94), urban (<i>OR</i>=1.12, 95%<i>CI</i>: 1.04-1.21), central obesity (<i>OR</i>=2.14, 95%<i>CI</i>: 2.01-2.29), higher frequency of alcohol consumption (5-7 day/week: <i>OR</i>=1.24, 95%<i>CI</i>: 1.11-1.38), physical inactivity (<i>OR</i>=1.09, 95%<i>CI</i>: 1.02-1.17) were risk factors for diabetes, while aging (30-39 years old: <i>OR</i>=1.53, 95%<i>CI</i>: 1.31-1.79; 40-49 years old: <i>OR</i>=2.36, 95%<i>CI</i>: 2.01-2.76; 50-59 years old: <i>OR</i>=3.03, 95%<i>CI</i>: 2.58-3.55; 60-69 years old: <i>OR</i>=4.22, 95%<i>CI</i>: 3.58-4.97; 70-79 years old: <i>OR</i>=5.05, 95%<i>CI</i>: 4.23-6.04; 80 years old and above: <i>OR</i>=6.08, 95%<i>CI</i>: 4.86-7.61), nationality: (Li minority group: <i>OR</i>=1.18, 95%<i>CI</i>: 1.10-1.28; other ethnic groups: <i>OR</i>=1.40, 95%<i>CI</i>: 1.14-1.71), urban (<i>OR</i>=1.12, 95%<i>CI</i>: 1.04-1.19), central obesity (<i>OR</i>=1.72, 95%<i>CI</i>: 1.62-1.83), higher frequency of alcohol consumption (1-4 day/week: <i>OR</i>=1.12, 95%<i>CI</i>: 1.01-1.23; 5-7 day/week: <i>OR</i>=1.35, 95%<i>CI</i>: 1.22-1.49) were risk factors for pre-diabetes. <b>Conclusions:</b> The epidemic situation of diabetes and pre-diabetes among adult residents in Hainan Province was not optimistic. In order to control the development of abnormal blood glucose, measures and targeted health education should be carried out to strengthen the screening","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"700-708"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Awareness of HCV infection status and willingness for ribonucleic acid testing among hepatitis C cases in four provinces in China]. [中国四省丙型肝炎患者对丙型肝炎病毒感染状况的知晓程度和核糖核酸检测意愿]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240929-00604
J J Yu, X B Zhang, N Li, H Tang, S D Ye, J Li, Z F Liu, D D Yang, J Han
{"title":"[Awareness of HCV infection status and willingness for ribonucleic acid testing among hepatitis C cases in four provinces in China].","authors":"J J Yu, X B Zhang, N Li, H Tang, S D Ye, J Li, Z F Liu, D D Yang, J Han","doi":"10.3760/cma.j.cn112338-20240929-00604","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240929-00604","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the awareness of HCV infection status and willingness for HCV-RNA testing among hepatitis C cases in four provinces in China and to provide a reference for adjusting HCV prevention and control strategies. <b>Methods:</b> From September 2021 to September 2022, a cross-sectional survey was conducted using stratified random cluster sampling in four provinces (Jiangsu, Henan, Hubei, and Yunnan) in China, with an estimated sample size of 6 468 participants. The questionnaire included sociodemographic information, HCV infection awareness, willingness for HCV-RNA testing, and history of high-risk behaviors from the survey participants. Logistic regression models were used to analyze the factors associated with HCV infection awareness and willingness for HCV-RNA testing among hepatitis C cases. Statistical analysis was performed using R 4.1.3 software. <b>Results:</b> A total of 10 563 hepatitis C cases were surveyed. The awareness rate of HCV infection was 86.74% (9 162/10 563), and the willingness rate for HCV-RNA testing was 85.21% (9 001/10 563). Multivariate logistic regression models analysis showed that the awareness rate of HCV infection was lower among individuals aged ≥60 years, urban residents (with New Rural Cooperative Medical Insurance ), those without a history of blood transfusion, those without a history of paid blood donation, those without a history of injection drug use, and those without a family member with hepatitis C case.The awareness rate was higher among individuals with high or technical secondary school education, college education or above, and those married with a spouse (all <i>P</i><0.05). In terms of willingness for HCV-RNA testing, it was lower among females, individuals aged ≥60 years, and those without a history of blood transfusion, paid blood donation, or injection drug use. The willingness was higher among farmers or migrant workers, employees of enterprises or institutions, and those in other occupations (all <i>P</i><0.05). <b>Conclusions:</b> There was room for improvement in the awareness proportion of HCV infection and willingness for HCV-RNA testing among hepatitis C cases in the four provinces of China. More convenient policies and measures should be provided to increase the awareness rate of HCV infection and the willingness to undergo HCV-RNA testing in this population.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"688-694"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Study on the association between compound hot extremes and fall death risk in three provinces of southern China]. [中国南方三省复合极端高温与秋季死亡风险的相关性研究]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240911-00570
L L Xie, J M Zeng, J Wan, Z H Tang, R L Meng, C L Zhou, M Yu, Y Lin, W Q Zeng, W J Ma, G H He
{"title":"[Study on the association between compound hot extremes and fall death risk in three provinces of southern China].","authors":"L L Xie, J M Zeng, J Wan, Z H Tang, R L Meng, C L Zhou, M Yu, Y Lin, W Q Zeng, W J Ma, G H He","doi":"10.3760/cma.j.cn112338-20240911-00570","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240911-00570","url":null,"abstract":"<p><p><b>Objective:</b> To explore the risk fall death associated with compound hot extremes. <b>Methods:</b> This study collected data on fall deaths in Guangdong, Hunan, and Zhejiang Provinces from 2013 to 2018 and matched their exposure to meteorological data. Based on a time-stratified case-crossover design, a conditional logistic regression model embedded with a cross-basis function of the distributed lag nonlinear model was applied to estimate the risk of fall to death due to compound hot extremes. <b>Results:</b> Compared with regular days, compound hot extremes significantly increased the risk of death from falls (<i>OR</i>=1.19, 95%<i>CI</i>: 1.09-1.30), and women (<i>OR</i>=1.27, 95%<i>CI</i>: 1.11-1.45) and the elderly age 65 and above (<i>OR</i>=1.24, 95%<i>CI</i>: 1.12-1.39) were more sensitive to compound hot extremes. The maximum duration of compound hot extremes was 7 days, and the maximum intensity was 6.2 ℃, and the duration and intensity were proportional to the risk of death from falls. The risk of death from falls increased by 12% (<i>OR</i>=1.12, 95%<i>CI</i>: 1.06-1.18) each day, increasing in duration after linearization. The risk of death from falls increased by 16% (<i>OR</i>=1.16, 95%<i>CI</i>: 1.10-1.22) for each 1 ℃ increase in linearized intensity. <b>Conclusion:</b> Compound hot extremes increase the risk of death cases from falls.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"581-586"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Associations of plasma metabolites with mortality in Chinese adults: a prospective study]. [血浆代谢物与中国成人死亡率的关系:一项前瞻性研究]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20241209-00780
T Wu, S Y Song, Y J Pang, C Q Yu, D J Y Sun, P Pei, H D Du, J S Chen, Z M Chen, A Pan, J Lyu, L M Li
{"title":"[Associations of plasma metabolites with mortality in Chinese adults: a prospective study].","authors":"T Wu, S Y Song, Y J Pang, C Q Yu, D J Y Sun, P Pei, H D Du, J S Chen, Z M Chen, A Pan, J Lyu, L M Li","doi":"10.3760/cma.j.cn112338-20241209-00780","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241209-00780","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the prospective associations between plasma metabolites and the risks of all-cause and cause-specific mortality among Chinese adults. <b>Methods:</b> This study analyzed plasma metabolomics data from 2 183 healthy adults in the China Kadoorie Biobank (CKB), measured using targeted mass spectrometry. Cox proportional hazards regression models were used to examine the associations between 630 metabolites and the risk of all-cause mortality. Cause-specific hazard regression models evaluated the associations between metabolites and cardiovascular disease (CVD) risks, cancer, and other-cause mortality. Stepwise regression was used to identify key metabolites independently associated with all-cause mortality, and the area under the receiver operating characteristic curve (AUC) was calculated to assess the improvement in predictive performance when these metabolites were added to traditional risk prediction models. <b>Results:</b> The mean age of the participants was (53.2±9.8) years, 65.1% of whom were female. During a median follow-up of 14.5 years, 231 deaths occurred. A total of 44 metabolites were significantly associated with the risk of all-cause mortality [false discovery rate (FDR)-adjusted <i>P</i><0.05], primarily including triglycerides, ceramides, and amino acids. Additionally, 29 and 15 metabolites were found to be associated with cancer and other-cause mortality, respectively, but no metabolites were significantly associated with CVD mortality after FDR corrections. Adding 14 metabolites independently associated with all-cause mortality into the traditional prediction model significantly improved its predictive performance. Specifically, incorporating metabolites into the traditional model, which already included laboratory biomarkers, increased the AUC to 0.798 (95%<i>CI</i>: 0.755-0.843), an improvement of 0.088 compared to the traditional model (<i>P</i><0.001). <b>Conclusions:</b> Multiple metabolites are significantly associated with mortality risk and can substantially improve the accuracy of mortality risk prediction models. These findings provide new insights into the physiological mechanisms of aging and offer valuable clues for personalized health risk assessment.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"557-565"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Study on the association between temperature and the risk of injuries by animals in Guangdong Province]. [温度与广东省动物伤害风险的关系研究]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240910-00565
W Q Zeng, Y J Xu, A X Zheng, J X Hu, Y Fang, M E Guo, K Q Liang, S H Ye, Q J Zhu, G H He, T Liu, R L Meng, W J Ma
{"title":"[Study on the association between temperature and the risk of injuries by animals in Guangdong Province].","authors":"W Q Zeng, Y J Xu, A X Zheng, J X Hu, Y Fang, M E Guo, K Q Liang, S H Ye, Q J Zhu, G H He, T Liu, R L Meng, W J Ma","doi":"10.3760/cma.j.cn112338-20240910-00565","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240910-00565","url":null,"abstract":"<p><p><b>Objective:</b> To assess the association between temperature and risk of animal injury, and identifying vulnerable populations. <b>Methods:</b> Based on a time-stratified case-crossover design, the number of animal injuries monitored in hospitals of Guangdong Provincial Injury Surveillance System in 2011 and 2015-2016 was included, and the daily meteorological data were derived from the fifth generation of European ReAnalysis-Land, which was produced by the European Centre for Medium-Range Weather Forecasts. Conditional logistic regression combined with a distributed lagged nonlinear model was applied to analyze the association of temperature and animal-specific injuries. We also conducted stratified analysis by region, sex, age, occupation, and location of injury occurrence. <b>Results:</b> There was an almost linear relationship between temperature and the occurrence of animal injury. The excess risk (<i>ER</i>) of animal injury was 2.65% (95%<i>CI</i>: 2.27%-3.04%) for a 1 ℃ rise in temperature with much higher risk of occurrence (<i>ER</i>=9.34%, 95%<i>CI</i>: 7.57%-11.13%) for non-mammalian injury than that for mammalian injuries (<i>ER</i>=2.30%, 95%<i>CI</i>: 1.90%-2.70%). Stratified analysis revealed that the occurrence of animal injury was more susceptible to temperature influences in urban (<i>ER</i>=2.78%, 95%<i>CI</i>: 2.35%-3.21%), female (<i>ER</i>=2.71%, 95%<i>CI</i>: 2.16%-3.27%), the elderly aged 60 years and above (<i>ER</i>=3.05%, 95%<i>CI</i>: 1.65%- 4.47%), farmer (<i>ER</i>=4.66%, 95%<i>CI</i>: 3.03%-6.32%) and agricultural area (<i>ER</i>=10.63%, 95%<i>CI</i>: 7.57%-13.79%) than their correspondents. In terms of mammalian injury, dog bites showed the highest risk (<i>ER</i>=2.71%, 95%<i>CI</i>: 2.12%-3.30%). In terms of non-mammalian,snake injuries were highly influenced by temperature (<i>ER</i>=16.74%, 95%<i>CI</i>: 11.33%-22.40%). <b>Conclusions:</b> The ambient temperature rises could increase the risk of animal injury with much higher risk for non-mammalian than that for mammalian injuries. Our findings suggest that global warming may increase the risk and disease burden from animal injuries.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"587-595"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Analysis of HIV antibody positivity and influencing factors among new type drug users at AIDS surveillance posts in Zhejiang Province from 2017 to 2023]. 2017 - 2023年浙江省艾滋病监测点新型吸毒人员HIV抗体阳性及影响因素分析
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240924-00593
Z Yuan, Y Xu, W Cheng, J Z Yang, J Jiang, L Chen, X H Pan
{"title":"[Analysis of HIV antibody positivity and influencing factors among new type drug users at AIDS surveillance posts in Zhejiang Province from 2017 to 2023].","authors":"Z Yuan, Y Xu, W Cheng, J Z Yang, J Jiang, L Chen, X H Pan","doi":"10.3760/cma.j.cn112338-20240924-00593","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240924-00593","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the HIV antibody positivity of new type drug users in drug abuse monitoring sites in Zhejiang Province from 2017 to 2023 and its influencing factors. <b>Methods:</b> From 2017 to 2023, a continuous cross-sectional survey was carried out in HIV monitoring posts among new type drug users in Zhejiang Province,the sample size was 400 people per site of 9 drug abuse surveillance sites in 7 cities. Questionnaires were conducted to investigate their social demographic information, related behavioral information, AIDS awareness, and acceptance of intervention measures, and blood was collected for HIV and syphilis antibody detection, with new type drugs users in the monitoring population as the research object. SPSS 22.0 software was used for statistical analysis. <b>Results:</b> A total of 13 955 new drug users were surveyed, and the number of new drug users was 2 518, 2 292, 2 526, 2 119, 2 161, 1 064 and 1 275 from 2017 to 2023, respectively, the HIV antibody positive rate of new type drugs users was 0.44%, 1.09%, 2.06%, 1.09%, 1.39%, 1.50%, 2.90%, respectively, and the HIV antibody positive standardized rate showed an increasing trend (all <i>P</i><0.001). The results of multivariate logistic regression analysis showed that marital status: unmarried/divorced/widowed (a<i>OR</i>=3.92, 95%<i>CI</i>: 2.46-6.25), provincial household registration (a<i>OR</i>=3.54, 95%<i>CI</i>: 2.34-5.35), high school education or above (a<i>OR</i>=5.42, 95%<i>CI</i>: 3.68-7.98), sexual activity within the last 1 year after drug use (a<i>OR</i>=1.84, 95%<i>CI</i>: 1.19-2.84), and knowledge that the use of new drugs increases the risk of HIV infection (a<i>OR</i>=2.27, 95%<i>CI</i>: 1.17-4.39) were associated with increased HIV antibody favorable rates among new type drugs users. <b>Conclusions:</b> During 2017-2023, the HIV antibody-positive rate of new type drug users in Zhejiang Province showed an upward trend. It is necessary to strengthen the monitoring and intervention of this population.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"662-668"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Study on the physical activity levels and all-cause mortality risk in diabetic kidney disease patients and mediating effect of inflammation]. [糖尿病肾病患者体力活动水平、全因死亡风险及炎症介导作用的研究]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240816-00504
S S Tian, F Zhang, H Q Hao, X S Zhou
{"title":"[Study on the physical activity levels and all-cause mortality risk in diabetic kidney disease patients and mediating effect of inflammation].","authors":"S S Tian, F Zhang, H Q Hao, X S Zhou","doi":"10.3760/cma.j.cn112338-20240816-00504","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240816-00504","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the association between physical activity levels and all-cause mortality risk in patients with diabetic kidney disease (DKD) and to investigate the mediating effect of inflammation. <b>Methods:</b> Based on National Health and Nutrition Examination Survey of America data matched with the National Death Index of America, a prospective cohort was formed, including 59 482 participants from six cycles between 2007 and 2018. After applying inclusion and exclusion criteria, 2 214 DKD patients were selected for the study. Cox proportional hazard regression models were used to analyze the impact of physical activity levels on all-cause mortality risk. The mediating effect of inflammatory markers in the association between physical activity and all-cause mortality risk was explored. <b>Results:</b> There were statistically significant differences in survival curves among different physical activity level groups (<i>P<</i>0.001). As physical activity levels increased, the risk of mortality decreased. Patients in the high physical activity group had a lower mortality risk compared to those in the inactive group (<i>HR</i>=0.64, 95%<i>CI</i>: 0.53-0.78), with a statistically significant difference (<i>P</i><0.001). Patients with higher physical activity levels had lower levels of inflammation (white blood cell, neutrophil, and C-reactive protein) (<i>P</i><0.001). White blood cell, neutrophil, C-reactive protein, the neutrophil-to-lymphocyte ratio (NLR), and the systemic inflammation index (SII) were independent risk factors for mortality in DKD patients (<i>HR</i>>1.00), with higher risk effects observed for the combined indicator lgNLR (<i>HR</i>=2.06, 95%<i>CI</i>: 1.76-2.41) and lgSII (<i>HR</i>=1.44, 95%<i>CI</i>: 1.26-1.64). Mediation analysis showed that physical activity had an indirect effect on all-cause mortality risk through neutrophil, with an effect size of -0.033 (95%<i>CI</i>: -0.052 - -0.002), which was statistically significant (<i>P</i><0.05), with a mediation effect proportion of 9.75%. <b>Conclusion:</b> Physical activity is a protective factor against all-cause mortality risk in DKD patients, partly through reducing neutrophil levels.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"717-723"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Study on the association between heatwaves and road traffic injury mortality in five provinces of China]. [中国五省热浪与道路交通伤害死亡率的关系研究]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240911-00568
S W Yu, M Yu, A X Zheng, C L Zhou, R L Meng, B Huang, Y Z Xiao, W Wu, G H He, J X Hu, W J Ma, T Liu
{"title":"[Study on the association between heatwaves and road traffic injury mortality in five provinces of China].","authors":"S W Yu, M Yu, A X Zheng, C L Zhou, R L Meng, B Huang, Y Z Xiao, W Wu, G H He, J X Hu, W J Ma, T Liu","doi":"10.3760/cma.j.cn112338-20240911-00568","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240911-00568","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the impact of short-term exposure to daytime heatwaves, nighttime heatwaves, and compound heatwaves on the risk of road traffic mortality and calculate the attributable mortality burden. <b>Methods:</b> This study collected road traffic mortality data from the Disease Surveillance System in Guangdong, Hunan, Zhejiang, Yunnan, and Jilin Provinces from 2013 to 2018. A time-stratified case-crossover design was used in this study, with the death date for each case serving as the case day. Control days were selected from the same year, month, and day of the week as the case day. A conditional logistic regression model was employed to estimate the cumulative associations of short-term exposure to daytime heatwaves, nighttime heatwaves, and compound heatwaves on the risk of road traffic mortality (lag 0-1 day) and to calculate the attributable fractions (AF). <b>Results:</b> Compared to non-heatwave days, the excess risk (<i>ER</i>) of road traffic mortality on daytime heatwave days, nighttime heatwave days, and compound heatwave days was 5.3% (95%<i>CI</i>: 0.5%-10.2%), 4.9% (95%<i>CI</i>: 0.5%-9.4%) and 7.5% (95%<i>CI</i>: 2.3%- 12.9%), with corresponding AF of 5.0% (95%<i>CI</i>: 0.5%-9.3%), 4.7% (95%<i>CI</i>: 0.5%-8.6%), and 6.9% (95%<i>CI</i>: 2.3%-11.4%), respectively. Stratified analysis showed that the risk of traffic mortalities caused by daytime heatwaves was higher in females (<i>ER</i>=15.7%, 95%<i>CI</i>: 5.8%-26.5%) than in males (<i>ER</i>=1.8%, 95%<i>CI</i>: -3.6%-7.4%). Elderly individuals over 64 years old (<i>ER</i>=10.9%, 95%<i>CI</i>: 0.3%- 22.6%) had a higher risk of road traffic mortalities from compound heatwaves than those under 45 years old (<i>ER</i>=2.6%, 95%<i>CI</i>: -5.4%-11.2%). The risk of road traffic injury mortality from motor vehicle accidents caused by compound heatwaves (<i>ER</i>=16.6%, 95%<i>CI</i>:2.4%-32.7%) was higher than that from non-motor vehicle accidents (<i>ER</i>=5.7%, 95%<i>CI</i>:0.1%-11.5%). <b>Conclusions:</b> Short-term exposure to daytime heatwaves, nighttime heatwaves, and compound heatwaves was associated with an increased risk of road traffic mortality, with the strongest association observed for compound heatwaves. The mortality burden attributable to compound heatwaves was higher than that for daytime and nighttime heatwaves. Heatwaves were more significantly associated with road traffic mortality risk among females, elderly individuals over 64 years old, and motor vehicle accidents.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"573-580"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144021884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The spatio-temporal trend of female breast cancer incidence and mortality in Shandong Province from 2012 to 2023 and trend prediction]. [2012 - 2023年山东省女性乳腺癌发病率和死亡率时空趋势及趋势预测]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240830-00539
F Jiang, Z T Fu, Q F Wang, J Chu, B Y Zhang, Z L Lu, X L Guo, A Q Xu
{"title":"[The spatio-temporal trend of female breast cancer incidence and mortality in Shandong Province from 2012 to 2023 and trend prediction].","authors":"F Jiang, Z T Fu, Q F Wang, J Chu, B Y Zhang, Z L Lu, X L Guo, A Q Xu","doi":"10.3760/cma.j.cn112338-20240830-00539","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240830-00539","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; We aimed to analyze the spatio-temporal trend of breast cancer incidence and mortality in Shandong Province from 2012 to 2023 and predict the development trend from 2024 to 2030. &lt;b&gt;Methods:&lt;/b&gt; Data on the incidence and mortality of breast cancer in Shandong Province from 2012 to 2023 were obtained from the Shandong Cancer Registry. The incidence, age-specific incidence, mortality, and age-specific mortality in different years, as well as in urban and rural areas, were calculated, and the rates were standardized based on the age composition of the Chinese standard population in 2000. The average annual percent change (AAPC) rate was calculated using Joinpoint 4.8.0.1 software. The global and local spatial autocorrelation analysis were performed using GeoDa 1.12 software. The Bayesian age-period-cohort model was used to predict the trend of breast cancer incidence and mortality from 2024 to 2030. &lt;b&gt;Results:&lt;/b&gt; From 2012 to 2023, the breast cancer age-standardized incidence rate (ASIR) showed an increasing trend. The ASIR increased from 30.48/100 000 in 2012 to 39.94/100 000 in 2023 (AAPC=2.59%, &lt;i&gt;P&lt;/i&gt;&lt;0.001). The ASIR of urban and rural females also showed an upward trend. Additionally, the ASIR in rural areas (AAPC=3.33%, &lt;i&gt;P&lt;/i&gt;&lt;0.001) increased more than that in urban areas (AAPC=1.83%, &lt;i&gt;P&lt;/i&gt;=0.002). The incidence peak of breast cancer mainly concentrated in population aged 45-64 years, and with the increase of years, the incidence peak gradually moved forward. The age-standardized mortality rate (ASMR) showed a downward trend. The ASMR decreased from 6.89/100 000 in 2012 to 4.93/100 000 in 2023 (AAPC=-3.12%, &lt;i&gt;P&lt;/i&gt;&lt;0.001). The ASMR of urban and rural females also showed a downward trend (urban: AAPC=-3.56%, &lt;i&gt;P&lt;/i&gt;=0.007; rural: AAPC=-2.72%, &lt;i&gt;P&lt;/i&gt;&lt;0.001). The spatial analysis showed that from 2015 to 2023, the clustering areas of breast cancer incidence and mortality in Shandong had changed significantly. In 2015, the \"High-high clusters\" of ASIR mainly included Wendeng District in Weihai City, Dongying District, Kenli District, Lijin County, Guangrao County in Dongying City, Tianqiao District, Shizhong District in Jinan City; In 2023, the \"High-high clusters\" mainly included Jiaxiang County, Liangshan County, Jinxiang County, Wenshang County, Rencheng District in Jining City, Hedong District in Linyi City, Guangrao County in Dongying City. In 2015, the \"High-high clusters\" of ASMR only included Wenshang County in Jining City. In 2023, the \"High-high clusters\" mainly included Laizhou County in Yantai City, Junan County and Yishui County in Linyi City, Gaotang County in Liaocheng City, Dongping County and Ningyang County in Taian City. The Bayesian age-period-cohort model predicted that the ASIR trend of breast cancer in Shandong tended to be smooth (AAPC=0.33%, &lt;i&gt;P&lt;/i&gt;=0.001). However, the ASMR remained decreasing (AAPC=-4.68%, &lt;i&gt;P&lt;/i&gt;&lt;0.001). &lt;b&gt;Conclusions:&lt;/b&gt; The breast cancer incidence in Shandong ","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"646-654"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Current situation of e-cigarettes and its relationship with smoking and smoking cessation among residents aged 18-65 in Beijing]. [北京市18-65岁居民电子烟现状及其与吸烟、戒烟的关系]。
中华流行病学杂志 Pub Date : 2025-04-10 DOI: 10.3760/cma.j.cn112338-20240809-00489
B Jiang, A J Ma, J Xie, C Xie, X Y Han, L Nie, Y Q Wei, K Fang, J Dong, Y Zhao, Z Dong
{"title":"[Current situation of e-cigarettes and its relationship with smoking and smoking cessation among residents aged 18-65 in Beijing].","authors":"B Jiang, A J Ma, J Xie, C Xie, X Y Han, L Nie, Y Q Wei, K Fang, J Dong, Y Zhao, Z Dong","doi":"10.3760/cma.j.cn112338-20240809-00489","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240809-00489","url":null,"abstract":"<p><p><b>Objective:</b> To understand the usage situation of e-cigarettes among residents aged 18-65 in Beijing, explore the relationship between e-cigarette use and cigarette smoking as well as smoking cessation behaviors, and provide scientific support for the developing and improving policies and measures related to e-cigarettes. <b>Methods:</b> Using 19 684 residents data from the Beijing Non-communication Chronic Disease and Risk Factors Surveillance in 2022, complex sampling weighted methods were used to estimate proportions, and complex sampling logistic regression analysis was applied to explore the relationship between e-cigarette use, cigarette smoking, and smoking cessation. <b>Results:</b> Among all study participants, the proportion of those who had ever used e-cigarettes was 3.36%, with the current e-cigarette use at 1.26%. The proportion of current e-cigarette users (1.87%) and the former e-cigarette users (3.47%) were higher (<i>χ</i>²=64.70, <i>P</i><0.001) among males compared to females (0.60% and 0.64% respectively). The top three reasons for using e-cigarettes were wanting to quit smoking, perceiving e-cigarettes as less harmful, and enjoying the flavors of e-cigarettes. 83.54% of e-cigarette users started with cigarettes. The results of the complex sampling multivariable logistic regression analysis showed that current smoking (<i>OR</i>=61.35, 95%<i>CI</i>: 36.98-101.76) and former smoking (<i>OR</i>=31.20, 95%<i>CI</i>: 15.52-62.71) were positively associated with e-cigarette, while current e-cigarette use (<i>OR</i>=0.13, 95%<i>CI</i>: 0.04-0.39) was negatively associated with quitting cigarette smoking. <b>Conclusions:</b> The proportion of e-cigarette use in Beijing was relatively low. E-cigarette use was associated with cigarette use and was not conducive to smoking cessation. Therefore, stronger regulatory measures and health education campaigns regarding the risks of e-cigarettes should be implemented.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 4","pages":"638-645"},"PeriodicalIF":0.0,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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