中华流行病学杂志最新文献

{"title":"[Analysis of the consultation for services and related factors of post-exposure prophylaxis services among college students who were at high risk for HIV infection in Hangzhou].","authors":"X L Zhang, K Xu, Z Sun, X T Li, X H Pan, J F Chen","doi":"10.3760/cma.j.cn112338-20241219-00814","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241219-00814","url":null,"abstract":"<p><p><b>Objective:</b> To understand the consultation for post-exposure prophylaxis(PEP) services and their related factors among college students who were at high risk for HIV infection in Hangzhou,and to provide a reference basis for formulating an intervention model for college students at high risk of HIV infection. <b>Methods:</b> A cross-sectional survey was conducted between November 2022, and March 2023, in 5 different types of schools in Hangzhou. The subjects should meet the inclusion criteria of age between 18 years and 24 years old self-reported having ever had sex in the past. The sample size was estimated at 864. An online survey was conducted among college students by questionnaire star of an online survey platform to collect their demographic information, sexual behavior characteristics, HIV test status, and consultation for PEP services. The HIV infection risk among participants was evaluated according to their sexual behavior. The consultation for PEP services and the related factors of college students who were at high risk for HIV infection were analyzed. <b>Results:</b> A total of 20 973 college students were surveyed, and 2 291 who have ever had sex were recruited in the study. The proportion assessed as being at high risk for HIV infection was 43.47% (996/2 291), and the proportion of consultation for PEP services was 9.24% (92/996). Multivariate logistic regression analysis showed that among college students who were at high risk for HIV infection, the positive related factors of consultation for PEP services included knowing about PEP services (a<i>OR</i>=17.49, 95%<i>CI</i>: 7.98-38.36) ,having HIV tests (a<i>OR</i>=3.92, 95%<i>CI</i>: 2.08-7.42) and access to condoms on campus (a<i>OR</i>=3.38, 95%<i>CI</i>: 2.02-5.65), and the negative related factor was homosexual orientation (a<i>OR</i>=0.24, 95%<i>CI</i>: 0.06-0.91). <b>Conclusions:</b> Among college students who were at high risk for HIV infection, the proportion of consultation for PEP services was at a lower level. It is necessary to strengthen further the health education of PEP services knowledge among college students, improve the PEP services system, and promote the utilization of PEP services to reduce new HIV infections among college students.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"1008-1013"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Epidemiological characteristics of bacillary dysentery in China, 2005-2024].","authors":"Y F Zhang, F F Liu, Y Song, T Qin, D Jin, Z R Chang, B Kan","doi":"10.3760/cma.j.cn112338-20250311-00153","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20250311-00153","url":null,"abstract":"<p><p><b>Objective:</b> The objective of this study was to understand the incidence, spatial and temporal distribution characteristics and trends of bacillary dysentery in China from 2005 to 2024 in order to identify the high-risk groups and reveal the potential risk factors and to provide a scientific basis for optimizing the allocation of preventive and control resources, formulating targeted intervention strategies and assessing the effectiveness of the measures. <b>Methods:</b> The nationally reported incidence data of bacillary dysentery was collected from 2005 to 2024 in the Chinese Center for Disease Control and Prevention National Notifiable Diseases Reporting Information System. Descriptive epidemiological methods were used to analyze the population characteristics of bacillary dysentery cases. A Joinpoint regression model was constructed to examine long-term trends in reported incidence rates and spatial dynamic window scanning statistics were applied to detect spatial clusters of bacillary dysentery cases. <b>Results:</b> Between 2005 and 2024, 3 520 247 cases of bacillary dysentery were reported across China, with an average incidence rate of 12.88 per 100 000 people, after which the rate of decline decreased. The incidence rate showed a general downward trend, featuring a significant inflection point in 2016. It exhibited marked seasonality, peaking from May to October (summer-autumn), which weakened over time. From 2005 to 2024, the most likely clusters were in Beijing and Tianjin. Males, infants, the elderly, farmers, and children not in daycare showed many cases. <b>Conclusions:</b> The results revealed that the peak incidence of bacillary dysentery in China from 2005 to 2024 was featured in the summer-autumn months. High-incidence areas were mainly Beijing and Tianjin. The key groups, including males, infants, the elderly, farmers and children not in daycare, were identified. Enhancing surveillance, targeted health education, and preventive measures, especially in these key populations and in regions where the disease shows a high incidence should be strengthened.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"942-950"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Exploring the abnormal correlation between obesity and higher survival rate based on directed acyclic graphs and collider bias theory].","authors":"Y X Tian, Y Q Peng, T T Geng, G Liu, A Pan","doi":"10.3760/cma.j.cn112338-20240819-00511","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240819-00511","url":null,"abstract":"<p><p>In the general population, obesity (high BMI) is often considered as an important risk factor for many diseases and premature death. However, in patients with a certain disease, the risk of death in people with obesity was lower than that in people with normal weight. This abnormal correlation has caused widespread discussion, and different explanations have been given by physiology and epidemiology. Based on causal inference theory, this study used directed acyclic graphs to introduce the collision bias (also called collision-stratification bias). Through example demonstrations, this study explored whether and why the abnormal correlation between obesity and higher survival rates in patients with hyperglycemia exists. Finally, it was concluded that this abnormal correlation among patients with a certain disease (e.g., hyperglycemia in the current analysis) was partly or even totally caused by collider bias.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"1067-1072"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevalence and influencing factors of preserved ratio impaired spirometry in adults aged 40 years and above in 10 areas in China].","authors":"Y B Lan, X Y Zhang, D Z Wu, J Lyu, D J Y Sun, P Pei, H D Du, J S Chen, Z M Chen, L M Li, C Q Yu","doi":"10.3760/cma.j.cn112338-20241127-00754","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241127-00754","url":null,"abstract":"<p><p><b>Objective:</b> To describe the prevalence of preserved ratio impaired spirometry (PRISm) in participants from the China Kadoorie Biobank (CKB) and explore the influencing factors. <b>Methods:</b> The CKB project conducted the baseline survey, the first and the second resurvey in 2004-2008, 2008, and 2013-2014, respectively. Based on the lung function tests, the participants were categorized into three groups: regular, PRISm, and airflow obstruction. The prevalence of PRISm was reported by gender, age, and region at the baseline survey. The secular trend in the prevalence of PRISm was described during the three surveys. Finally, we used the multiple logistic regression model to examine the factors related to PRISm in the baseline survey. <b>Results:</b> After standardization for gender, age, and region according to the sixth national census data in 2010, the overall prevalence of PRISm and airflow obstruction among the 434 760 participants at baseline was 24.8% and 6.1%, respectively. The prevalence of PRISm was higher in rural (25.4%) than that in urban areas (24.3%). Of the 10 study regions, Gansu had the highest prevalence of PRISm (56.0%), while Henan had the lowest (15.4%). After standardization for gender, age, and region according to the baseline population, the prevalence of PRISm decreased from 24.9% at baseline to 15.7% in the second resurvey, and the prevalence of airflow obstruction increased from 5.9% to 21.4%. Unmarried status, current smoking, using solid fuels for cooking, low body weight, being overweight, obesity, and central obesity were associated with an increased risk of PRISm. In contrast, higher education attainments, increased household income, and maintaining a specific degree of physical activity were associated with a reduced risk of PRISm. <b>Conclusions:</b> The prevalence of PRISm was high in adults aged 40 years and above in China, and it varied by sociodemographic and lifestyle factors.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"929-934"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A cohort study on the association of healthy lifestyle with co-morbidity of overweight/obesity and myopia in adolescents].","authors":"L T Chu, F Y Zhang, W J Qi, S X Qu, Y T Yang, Y T Huang, S L Huang, K Y Zheng, D L Yang, C Y Luo","doi":"10.3760/cma.j.cn112338-20241028-00667","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241028-00667","url":null,"abstract":"<p><p><b>Objective:</b> To explore the association between healthy lifestyle and co-morbidity of overweight/obesity and myopia in adolescents. <b>Methods:</b> Based on the Shanghai Municipal Dynamic Cohort of Student Common Diseases, we used the group-based trajectory model (GBTM) to establish a model for the development of adolescents' healthy lifestyle trajectories aged 11-14 years and the Cox proportional hazard regression model to assess the effects of different healthy lifestyles on the co-morbidity of overweight/obesity and myopia in adolescents. <b>Results:</b> A total of 2 331 adolescents were included in the analysis. The average follow-up time was 1.87 years, with age of (11.44±0.45) years at the initial follow-up, among 1 106 boys and 1 225 girls. During the 2-year follow-up period, the incidence rates of overweight/obesity, myopia, and co-occurrence of overweight/obesity and myopia were 25.9%, 77.0%, and 13.7%, respectively. GBTM identified 3 healthy lifestyles: the unhealthy group (7.3%), the relatively healthy group (50.2%), and the healthy group (42.5%). The risk of overweight/obesity was lower in the relatively healthy group than in the unhealthy group (<i>HR</i>=0.694, 95%<i>CI</i>: 0.508-0.947). There was no statistically significant association between the GBTM lifestyle subgroups and myopia (<i>P</i>>0.05). The risk of co-occurrence of overweight/obesity and myopia was lower in both relatively healthy group and healthy group than in the unhealthy group (relatively healthy group: <i>HR</i>=0.515, 95%<i>CI</i>: 0.348-0.763; healthy group: <i>HR</i>=0.571, 95%<i>CI</i>: 0.384-0.849). Sensitivity analyses showed this result to be stable for myopia, overweight/obesity and myopia co-morbidities. <b>Conclusion:</b> Persistent unhealthy lifestyle increases the risk of overweight/obesity and myopia co-occurrence in adolescents.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"1023-1029"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of myopia detection rate and influencing factors among primary and secondary school students in Hunan Province in 2022].","authors":"S J Xiao, M Y Luo, Z H Huang, Y Zhou, F Wang, Y Q Tan, Y H Chen","doi":"10.3760/cma.j.cn112338-20240912-00572","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240912-00572","url":null,"abstract":"<p><p><b>Objective:</b> To determine the detection rate of myopia among primary and secondary school students in Hunan Province in 2022 and to analyze the influencing factors at both the school and individual levels, thereby providing a scientific basis for developing myopia prevention and control strategies. <b>Methods:</b> From October to November 2022, a multi-stage stratified cluster random sampling method was employed to select students from Year 4 of primary school to Year 3 of senior high school across 14 prefecture-level (autonomous prefecture) cities in Hunan Province for vision screening and questionnaire surveys. A multilevel regression model was utilized to analyze the influencing factors of myopia at both the school and individual levels. <b>Results:</b> A total of 189 343 primary and secondary school students were included in this study. The overall myopia detection rate was 55.56%, with a significantly higher prevalence observed in female students (60.49%) compared to males (51.03%) and in urban students (59.12%) versus those from rural areas (53.50%). A marked upward trend in myopia prevalence was identified with advancing grade levels (trend test <i>χ</i>²=16 246.13, <i>P</i><0.001). Multilevel regression analysis revealed that at the individual level, female gender, higher grade level, parental myopia history, daily homework duration ≥2 hours after school, improper reading/writing postures, and taking breaks only after more than 15 minutes of near work were associated with an increased risk of myopia. Conversely, adequate sleep duration, outdoor activity ≥2 hours, and outdoor breaks during recess demonstrated protective effects. At the school level, non-compliant blackboard illumination uniformity emerged as a significant risk factor for myopia development. <b>Conclusions:</b> The detection rate of myopia among primary and secondary school students in Hunan Province remains relatively high and is associated with multiple factors at both the school and individual levels. Targeted interventions should be implemented at different levels to mitigate the risk of myopia.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"1014-1022"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis of the epidemiological characteristics of self-injury/suicide cases at injury surveillance sentinel hospitals in Jiangsu Province from 2006 to 2022].","authors":"X Wu, W C Du","doi":"10.3760/cma.j.cn112338-20240919-00583","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240919-00583","url":null,"abstract":"<p><p><b>Objective:</b> To understanding the epidemiological characteristics of self-injury/suicide among residents in Jiangsu Province, as well as grasping the current situation and patterns, will provide support and a basis for reducing the occurrence of self-injury/suicide harm. <b>Methods:</b> Data on self-injury/suicide cases from 2006 to 2022 were collected from 12 national injury surveillance sentinel hospitals in Jiangsu Province. The prevalence characteristics were analyzed using R 4.2.1 software, employing the chi-square test and Post Hoc testing for pairwise comparisons between groups, with adjusted standardized residuals to assess group differences. <b>Results:</b> From 2006 to 2022, there were 5 504 cases of self-injury/suicide monitored in Jiangsu Province, comprising 2 016 males and 3 488 females, resulting in a male-to-female ratio of 1∶1.73. The top three months for self-injury/suicide incidents were June (10.12%), May (9.85%), and July (9.25%). The peak times for these incidents were between 00:00-01:00 and 20:00-21:00. The majority of self-harm/suicide incidents occurred at home (73.64%). The primary methods of self-harm/suicide were poisoning and injuries caused by sharp objects, accounting for 47.11% and 35.32%, respectively. The frequently injured body parts were the upper limbs (34.97%) and generalized injuries throughout the body (25.56%). In terms of severity, mild cases predominated (49.78%). Further analysis reveals that, compared to male, self-harm/suicidal characteristics, female self-harm/suicidal behavior is more likely to occur at home, with poisoning as the predominant method, injuries affecting multiple body areas, and the severity of injuries being relatively mild (<i>P</i><0.001). In the 15-29 age group, self-harm/suicidal injuries predominantly affect the upper limbs (<i>P</i><0.001). Self-harm/suicidal behavior is more likely to occur at home, with poisoning being the primary method, injuries affecting multiple body areas, and the severity of injuries being more severe (all <i>P</i><0.001) for individuals aged 60 and above. <b>Conclusions:</b> To prevent and control self-harm/suicidal behavior and reduce the suicide mortality rate, it is essential to strengthen support and care for key populations such as women, those aged 15 to 29, and individuals aged 60 and above. Monitoring and management should be enhanced in key locations where self-harm/suicide is more likely to occur, such as homes, public living spaces, schools, and public areas, to enable early detection. Controlling potential methods of suicide is crucial, such as continuing to strengthen regulations and restrictions on highly toxic pesticides and reducing the likelihood of fatal overdoses from medications.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"966-972"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Epidemiological and clinical characteristics of pertussis identified through active surveillance].","authors":"J Li, H Q He, Y Y Zhang, B H Chen, Y Gao, H Y Dai, J Xu, Y Zhu, T Fu, C W Chen, Q Q Zhou, L Xu, J Che, M J Zhang, Z J Shao","doi":"10.3760/cma.j.cn112338-20241211-00788","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241211-00788","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the epidemiological and clinical characteristics of pertussis cases identified through active surveillance. <b>Methods:</b> Active surveillance for pertussis was conducted in three sentinel hospitals in Yiwu, Zhejiang Province, and Yongcheng, Henan Province. The study population included cases that met the surveillance case definition and sought medical care at outpatient/emergency departments or were hospitalized between June 1, 2021, and May 31, 2022. Samples were collected for bacterial culture and PCR detection. Case information and clinical data were collected. Differences in rates were assessed using the chi-square test or Fisher's exact probability test, and the differences in cough time were compared using the Mann-Whitney <i>U</i> test. <b>Results:</b> Among 1 423 cases of pertussis surveillance, the positive rate of pertussis was 28.11% (400/1 423), with a median age of 5 years (interquartile range: 2, 8). The positive rate in Yongcheng, Henan Province, and Yiwu, Zhejiang Province were 39.27% (216/550) and 21.08% (184/873), respectively; the positive rate of pertussis was highest in July 2021, and the highest positive rate of pertussis was among those aged 10-14. The positive rate of pertussis in hospitalized cases was higher than in outpatient/emergency cases (26.68%) (<i>χ</i>²=4.16, <i>P</i>=0.041). Among the 400 laboratory test-positive cases, the highest proportion of atypical symptom cases was in adults aged 20-59 (43.33%, 13/30). The specificity rates of apnea and worsening nocturnal cough in monitored cases under 3 months of age were 100.00% and 73.81%, respectively. Among monitored cases aged 3 months to 9 years, the proportions of symptoms including worsening nighttime cough (63.00%) and night sweats (4.59%) in test-positive cases were significantly higher than those in the test-negative group (47.77% and 0.56%, respectively), with statistically significant differences (both <i>P</i><0.05). The specificity rates of worsened nighttime coughing and night sweats were 52.23% and 99.44%, respectively. <b>Conclusions:</b> The active surveillance results for pertussis showed that the 10-14 age group exhibited the highest positivity rate. Active surveillance enhanced the detection rate of pertussis. Among laboratory-confirmed cases, the proportion of atypical symptoms was the highest in adults, suggesting that laboratory testing should be combined to diagnose programs of pertussis. For infants under 3 months, worsening nighttime cough and apnea increase the diagnostic specificity, while for individuals aged 3 to 9 years old, worsening nighttime cough and night sweats increase the diagnostic specificity.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"1043-1050"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between remnant cholesterol and the risk of atherosclerotic cardiovascular disease in a community population in Shanghai].","authors":"Y Q Deng, M H Tang, K X Zhang, X H Liu, Y N Wu, Q Peng, L P Yi, J H Shi, Y F Lu, Y G Jiang, G M Zhao","doi":"10.3760/cma.j.cn112338-20241018-00641","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241018-00641","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the association between remnant cholesterol (RC) and the risk of atherosclerotic cardiovascular disease (ASCVD) in community population in Shanghai. <b>Methods:</b> Using baseline and follow-up data from the Shanghai Suburban Adult Cohort and Biobank, individuals with ASCVD (including coronary heart disease, stroke, myocardial infarction, and peripheral artery disease) at baseline were excluded. A Cox proportional hazards regression model was employed to analyze the relationship between RC and ASCVD risk and the association under different LDL-C levels. <b>Results:</b> A total of 57 281 participants were included, with a median follow-up of 5.61 person-years. During the follow-up, 1 436 ASCVD events (2.51%) were recorded. After adjusting for potential confounders, individuals with moderate (<i>HR</i>=1.18, 95%<i>CI</i>: 1.03-1.36) or high RC levels (<i>HR</i>=1.32, 95%<i>CI</i>: 1.15-1.51) had an increased risk of ASCVD. The association was stronger in participants younger than 60 years-old (interaction <i>P</i>=0.048). Participants with RC ≥0.97 mmol/L and LDL-C <3.40 mmol/L demonstrated a 19% (<i>HR</i>=1.19, 95%<i>CI</i>: 1.06-1.35) increased risk of ASCVD. When RC ≥0.97 mmol/L and LDL-C ≥3.40 mmol/L, ASCVD risk increased by 42% (<i>HR</i>=1.42, 95%<i>CI</i>: 1.21-1.67). <b>Conclusions:</b> Elevated RC increases ASCVD risk, regardless of LDL-C levels. RC can serve as a valuable predictor and intervention target for ASCVD.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"935-941"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Bayesian quantitative bias analysis of misclassification adjustment for prevalence].","authors":"J Liu, S W Tang, H Zhang","doi":"10.3760/cma.j.cn112338-20240924-00594","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20240924-00594","url":null,"abstract":"<p><p>In epidemiological research, accurate estimation of prevalence is important for understanding disease distribution, evaluating the effectiveness of interventions, and allocating health resources. However, the prevalence estimation is often influenced by misclassification bias. Quantitative bias analysis (QBA) can comprehensively evaluate the potential impact of bias on outcomes from three dimensions: bias type, level, and uncertainty. Although QBA research has been developed rapidly in the world in recent years, the introduction of QBA design principles, evaluation methods, and application cases is still insufficient in China. In our previous study, we introduced a new method for adjusting misclassification bias of prevalence and suggested the corresponding analytical tools. Based on the results of previous studies, this paper introduces the principles of QBA design, evaluation indexes, and the application of Bayesian methods in bias adjustment, which provide methodological support for epidemiologists conducting research in this field.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 6","pages":"1073-1078"},"PeriodicalIF":0.0,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}