中华流行病学杂志最新文献

{"title":"[Association between handgrip strength and chronic kidney disease in adult residents in Anhui Province].","authors":"W Xu, G D Xie, J Y Hu, D Dai, X Y Xing, H D Wang, Q He, J Q Xu, Y L Lyu, Q Y Cheng, Q L Meng","doi":"10.3760/cma.j.cn112338-20241125-00747","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241125-00747","url":null,"abstract":"<p><p><b>Objective:</b> To explore the independent association between handgrip strength and chronic kidney disease (CKD) in adult residents in Anhui Province using data from the China Adult Chronic Disease and Risk Factor Surveillance (2023). <b>Methods:</b> A multi-stage stratified cluster random sampling method was used to select residents aged ≥18 years for surveys, physical measurements, and laboratory tests. Relevant covariates were adjusted, and a multivariable logistic regression model was established to infer the association between handgrip strength and CKD, followed by subgroup analysis. <b>Results:</b> A total of 7 295 participants were included in the study, with age of (61.5±13.2) years, and 55.6% of the study participants were women. The results of the multivariate logistic regression analysis showed that with each 1.0 kg increase in handgrip strength, the risk for CKD decreased by 1.3% (<i>OR</i>=0.987, 95%<i>CI</i>: 0.978-0.997). Compared with those with low handgrip strength, the people with moderate hasdgrip strength (<i>OR</i>=0.818, 95%<i>CI</i>: 0.694-0.964) and high handgrip strength (<i>OR</i>=0.729, 95%<i>CI</i>: 0.598-0.989) had lower risk for CKD. In the subgroup analysis, the association between handgrip strength and risk for CKD remained unchanged regardless age, sex, smoking status, and alcohol consumption statuys, and the prevalence of hypertension and hyperlipidemia (interaction <i>P</i>>0.05), except BMI and diabetes. <b>Conclusion:</b> The decline in handgrip strength is associated with an increased risk for CKD in adult residents in Anhui.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1231-1236"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Spatiotemporal distribution of etiologically positive pulmonary tuberculosis in Shaanxi Province, 2015-2023].","authors":"K K Li, L H Dang, H W Zhang, Z Q He","doi":"10.3760/cma.j.cn112338-20250126-00064","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20250126-00064","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To understand the spatiotemporal distribution of pulmonary tuberculosis (TB) in Shaanxi Province from 2015 to 2023, and provide reference for the prevention and control of pulmonary TB in Shaanxi. &lt;b&gt;Methods:&lt;/b&gt; The registration data of etiologically positive pulmonary TB cases in Shaanxi from 2015 to 2023 were collected from the tuberculosis subsystem of Chinese Disease Control and Prevention Information System. Descriptive method was used to analyze the basic characteristics of the etiologically positive pulmonary TB cases. Linear trend &lt;i&gt;χ&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt; test was used to analyze trends in registration rate and pathogen positive rate. Software SPSS 25.0 was used for statistical analysis. Software ArcGIS 10.8 was used for global spatial autocorrelation and hotspot analysis to explore spatial clustering of the etiologically positive pulmonary TB cases. Software SaTScan 10.0 was used for spatiotemporal scan statistics, and software ArcGIS 10.8 was used to visualize the spatiotemporal clustering. &lt;b&gt;Results:&lt;/b&gt; A total of 64 148 cases of etiologically positive pulmonary TB were registered in Shaanxi from 2015 to 2023, with an average annual registration rate of 18.33/100 000. The registration rate and pathgen positive rate all showed upward trends from 2015 to 2023, and the differences were significant (the trend &lt;i&gt;χ&lt;/i&gt;&lt;sup&gt;2&lt;/sup&gt;=4 555.18 and 19 330.43, both &lt;i&gt;P&lt;/i&gt;&lt;0.001). Global spatial autocorrelation and hotspot analysis showed that the registration rate of etiologically positive pulmonary TB in Shaanxi from 2017 to 2023 showed a spatial clustering. The hotspots were mainly in Zhenba and Xixiang counties of Hanzhong, six counties (districts) of Ankang, and Yanchuan and Yanchang counties of Yan'an. The coldspots were mainly in parts of the Guanzhong area, including Baoji, Xi'an, and Xianyang. A total of 4 spatiotemporal clustering areas were explored by spatiotemporal scanning analysis (all &lt;i&gt;P&lt;/i&gt;&lt;0.001), in which the first-level clustering areas covered 17 counties (districts), mainly Zhenping, Ziyang, Zhenba, in southern Shaanxi from 2019 to 2022, the second-level clustering areas covered 6 counties (districts), mainly Yanchuan, Yanchang, Qingjian, in northern Shaanxi from 2018 to 2021, the third-level clustering areas covered 14 counties (districts), mainly Yanta, Chang'an, Jingyang, in Guanzhong area from 2018 to 2019, and the fourth-level clustering areas covered 10 counties (districts) from 2019 to 2021. &lt;b&gt;Conclusions:&lt;/b&gt; The registration rate of labortory confirmed pulmonary TB cases in Shaanxi showed an upward trend, with obvious differences in spatiotemporal clustering distribution. The clustering areas were mainly in southern Shaanxi, such as Zhenba, Zhenping, Hanbin, Langao, Pingli, Xunyang, Ziyang counties, and northern Shaanxi, such as Yanchuan and Yanchang counties, as well as in capital city, Xi'an and the adjacent Guanzhong area. It is necessary to develope targeted measures according to local","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1180-1187"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application of health big data in hospital-based cancer screening study].","authors":"C R Wang, Z M Guo, X Y Shi, Y D Zheng, Z L Luo, J X Xie, X L Chen, J B Li, Y J Xu, W Cao, F Wang, X S Dong, N Li, J He","doi":"10.3760/cma.j.cn112338-20241026-00664","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20241026-00664","url":null,"abstract":"<p><p>This paper focuses on the application of health big data in cancer screening. Firstly, the sources and characteristics of health big data are introduced, then the commonly used epidemiological designs and analytical techniques in hospital-based cancer screening studies are summarized and the application scenarios of such studies are described. Finally, the challenges and future development in the application of health big data are analyzed to provide reference for the future studies.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1297-1303"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Clinical research design and challenges of multi-conjugate vaccine and polyvalent vaccine].","authors":"H Y Liu, W W Han, M Z Gan, F C Zhu, J X Li","doi":"10.3760/cma.j.cn112338-20241025-00662","DOIUrl":"10.3760/cma.j.cn112338-20241025-00662","url":null,"abstract":"<p><p>Multi-conjugate vaccine and polyvalent vaccine can reduce the number of vaccinations, improve vaccination efficiency, and provide wider protection against diseases, and can not only brings convenience to recipients but also reduce healthcare costs, making it a key focus in modern vaccine development. However, even if the components of the vaccine are derived from already approved monovalent vaccines, it must still be considered as a new vaccine and undergo randomized controlled clinical trials to evaluate their safety and efficacy in humans. Due to the inclusion of multiple antigens, clinical evaluation must consider the potential interactions between or among the components, as well as the impacts of adjuvants, preservatives, and other ingredients on the vaccines' safety and efficacy. These factors introduce certain specific challenges in the clinical evaluation of multi-conjugate vaccine and polyvalent vaccine. This article summarizes the key elements and methods of clinical study design for multi-conjugate vaccine and polyvalent vaccine in terms of safety, immunogenicity, and protective efficacy, and discuss the problems and challenges exisitng in vaccine clinical evaluation to provide reference for the standardization of clinical study design of multi-conjugate vaccine and polyvalent vaccine.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1304-1310"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Progress in research of the definition of multimorbidity].","authors":"Z Y Chen, Y T Han, D J Y Sun, C Q Yu, Y J Pang, L M Li, J Lyu","doi":"10.3760/cma.j.cn112338-20241114-00725","DOIUrl":"10.3760/cma.j.cn112338-20241114-00725","url":null,"abstract":"<p><p>With the rapid global population aging, multimorbidity is becoming a more serious public health problem, to which medical researchers have paid close attention. A standardized definition of multimorbidity is essential for relevant research. However, there is a lack of consensus on the definition of multimorbidity, which makes it difficult to compare results among studies and replicate important findings. Based on the conceptual comparison, this paper summarizes the key dimensions of the definition of multimorbidity, including the number and types of conditions, the granularity of classification, methods for obtaining outcomes, and settings and objectives of research. It also discusses the inherent relationships among the dimensions and their impact on research results, and introduces the characteristics of the commonly used condition lists in current multimorbidity definition research. By suggesting areas for improvement in the multimorbidity definition system, it aims to enhance the understanding of multimorbidity research and achieve consensus on the definition, thereby facilitating further multimorbidity research.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1283-1288"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on diagnosis, treatment, and prevention of <i>Vibrio vulnificus</i> infection].","authors":"","doi":"10.3760/cma.j.cn112338-20250304-00132","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20250304-00132","url":null,"abstract":"<p><p><i>Vibrio vulnificus</i> (<i>V. vulnificus</i>) is a marine bacterium that can cause sepsis, characterized by rapid progression of infection and high clinical mortality rates. However, many healthcare workers lack systematic understanding of <i>V. vulnificus</i> infections and practical experience in the prevention and control of <i>V. vulnificus</i> infection. Therefore, joining with multidisciplinary experts, the Chinese Preventive Medicine Association established a special working group to formulate this consensus, aiming to provide guidance and reference for the diagnosis, treatment and prevention of <i>V. vulnificus</i> infection. Based on existing evidence and the latest research, 6 recommendations were formulated in terms of epidemiology, clinical manifestations, laboratory examination, early diagnosis, clinical evaluation, and infection treatment and prevention.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1142-1149"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevalence of smoking in people aged 15 years and above in Baoji, Shaanxi Province, 2013-2023].","authors":"Z Y Chen, H L Wang, P R Yang, L Zheng, F Deng","doi":"10.3760/cma.j.cn112338-20250411-00235","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20250411-00235","url":null,"abstract":"<p><p><b>Objective:</b> To understand the changes in the prevelance smoking in people aged ≥15 years in Baoji, and provide evidence for the improvement of tobacco control strategies. <b>Methods:</b> Data were from the sampling survey of chronic diseases and their risk factors conducted in Baoji at an interval of five years from 2013 to 2023. The survey used multi-stage cluster random sampling method to select local people aged ≥15 years, and the information about their tobacco use were collected by face-to-face interview. Descriptive epidemiological methods were used to analyze the prevalence of smoking, and <i>χ</i>² test was used to analyze the change trend. <b>Results:</b> The smoking rate in people aged ≥15 years in Baoji decreased from 2013 to 2023, and the standardized smoking rate decreased by 13.6% in 2023 compared with 2013. The standardized smoking cessation rate increased by 13.4% in 2018 compared with 2013, and the standardized smoking cessation rate decreased by 7.3% in 2023 compared with 2018. The standardized passive smoking rate decreased by 15.1% in 2018 compared with 2013, and the standardized passive smoking rate increased by 8.8% in 2023 compared with 2018. The average daily smoking amount increased by 3.7 cigarettes in 2018 compared with 2013, and the average daily smoking amount decreased by 3.9 cigarettes in 2023 compared with 2018. <b>Conclusion:</b> Progress has been made in tobacco control in Baoji, but problems still exist in tobacco control, to which close attention needs to be paid.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1237-1242"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Expert consensus on immunoprophylaxis of cervical cancer and other human papillomavirus- related diseases (2025 edition)].","authors":"","doi":"10.3760/cma.j.cn112338-20250530-00364","DOIUrl":"10.3760/cma.j.cn112338-20250530-00364","url":null,"abstract":"<p><p>There have been recent, significant changes in strategies and policies for elimination of cervical cancer and advances in research of human papillomavirus (HPV)-related diseases and their prevention and control. Based on the latest national and international research, and building on a consensus published in 2019, we developed an expert consensus on immunoprophylaxis of cervical cancer and other human papillomavirus-related diseases (2025 edition) in order to provide clinicians, disease prevention and control professionals, and vaccination staff a reference for the prevention and control of cervical cancer and other HPV-related diseases and systematic, comprehensive evidence-based support for the scientific use of HPV vaccines to optimize their prevention effectiveness.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 ","pages":"1107-1141"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Progress in research of textual quality evaluation of health-related media reports].","authors":"L Yang, M Zhao, S Y Zhao, W X Xiao, P X Cheng, G Q Hu","doi":"10.3760/cma.j.cn112338-20241012-00629","DOIUrl":"10.3760/cma.j.cn112338-20241012-00629","url":null,"abstract":"<p><p><b>Objective:</b> To summarize the progress in the research of textual quality evaluation of health-related media reports. <b>Methods:</b> A systematic literature retrieval about textual quality evaluation of health-related media reports based on PubMed, Web of Science, Embase, Wanfang database, and China National Knowledge Infrastructure was conducted. Information regarding the textual quality definition, evaluation dimensions, indicators and methods of included papers was extracted. <b>Results:</b> A total of 29 study papers were included in this analysis, in which 26 were about retrospective textual quality evaluation of health-related media reports, and 3 were about the model or tool development for textual quality evaluation of health-related media reports. The topics of news reports included: 16 studies on injury, 3 on general health, 3 on infectious disease, 3 on cancer screening and treatment, 3 on chronic non-communicable disease, and 1 on medication risk. The definition of textual quality of health-related media reports and the dimensions of the quality evaluation varied across the studies. The quality evaluation indicators of media reports can be divided into three categories: availability of surveillance information, availability of professional information, and adherence to principles of media reporting. Most studies conducted the quality evaluation manually, with only 2 studies employing semi-automated or automated evaluation methods. <b>Conclusions:</b> No unified definition, set of dimensions, indicators, or automated algorithms exist for evaluating the textual quality of health-related media reports, which limits assessing massive news data effectively. It is necessary to conduct methodological studies on the textual quality evaluation of health-related media reports based on journalism and communication theory, infodemiology, deep learning, natural language processing, text mining, as well as specific disease and injury prevention theory.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1269-1275"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Age-period-cohort analysis on disease burden of <i>Chlamydia trachomatis</i> infection in women aged 15-49 years in China, 1990-2021].","authors":"Y Q Yang, X D Ye, Q Luo, W P He, C Mao","doi":"10.3760/cma.j.cn112338-20250101-00002","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20250101-00002","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the incidence rate and disability-adjusted life year (DALY) rate of <i>Chlamydia trachomatis</i> (<i>C. trachomatis</i>) infection in women aged 15-49 years in China from 1990 to 2021, identify the vulnerable populations, and provide evidence for the prevention and control of <i>C. trachomatis</i> infection. <b>Methods:</b> The data from Global Burden of Disease Study 2021 were used to analyze the incidence rate and DALY rate of <i>C. trachomatis</i> infection in women aged 15-49 years in China from 1990 to 2021 by using Joinpoint regression model. The age-period-cohort analysis method was used to decompose the age effect, period effect and cohort effect of incidence rate and DALY rate of <i>C. trachomatis</i> infection. <b>Results:</b> From 1990 to 2021, the incidence rate of <i>C. trachomatis</i> infection increased from 5 892.02/100 000 in 1990 to 7 402.23/100 000 in 2021 in women aged 15-49 years in China. The DALY rate increased from 1.92/100 000 person-years in 1990 to 2.00/100 000 person-years in 2021. Joinpoint regression showed that, from 1990 to 2021, the annual incidence of <i>C. trachomatis</i> infection in Chinese women age aged 15-49 years increased by 0.74% [average annual percent change (AAPC) =0.74%, 95%<i>CI:</i> 0.67%-0.81%, <i>t</i>=21.94, <i>P</i><0.001] and the annual average DALY rate increased by 0.11% (AAPC=0.11%, 95%<i>CI:</i> -0.09%-0.30%, <i>t</i>=1.06, <i>P</i>=0.287). Age-period-cohort model analyses showed that women aged 30-34 years were at high risk to be infected with <i>C. trachomatis</i> and women aged 40-44 years were at high risk to have high DALY. The period effect showed that the risk for <i>C. trachomatis</i> infection began to increase in 1990, peaked during 2000-2004, then gradually decreased. During 2015-2019, the infection risk increased again, while the risk for high DALY showed a decreasing trend. The cohort effect showed that the risks for <i>C. trachomatis</i> infection and DALY were lower in later birth cohorts. <b>Conclusions:</b> From 1990 to 2021, the incidence rate and DALY rate of <i>C. trachomatis</i> infection showed fluctuations in women aged 15-49 years in China. It is necessary to pay close attention to the prevention and control of <i>C. trachomatis</i> infection in women aged 30-34 years.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"46 7","pages":"1168-1174"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}