中华流行病学杂志最新文献

{"title":"[Spatial accessibility and resource allocation of prehospital emergency medical services in Guangzhou].","authors":"S J Xia, Y Y Jin, D F Gan, R Zeng, H B Luo, S Y Cao, Z Y Liang, X F Liang, S Zhu","doi":"10.3760/cma.j.cn112338-20251118-00836","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251118-00836","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the spatial accessibility and resource allocation of prehospital emergency medical services (PEMS) in Guangzhou and provide evidence for network optimization and resource allocation. <b>Methods:</b> The data from 2 842 communities/village committees and 150 \"120\" network hospitals, including emergency medical service (EMS) stations, were used. Spatial accessibility was evaluated by using the nearest-neighbor (minimum travel time/distance) approach and the enhanced two-step floating catchment area (E2SFCA) method; spatial clustering was tested with global and local Moran's <i>I</i>, and emergency resource allocation was evaluated by using Lorenz curve and Gini coefficient. <b>Results:</b> By the nearest-neighbor analysis, the shortest travel time from communities in the central urban area to the nearest EMS station were 7.93-9.90 minutes, whereas it exceeded 12.00 minutes in many peripheral districts (e.g., Nansha District). E2SFCA indicated higher accessibility in parts of Conghua and Zengcheng Districts, but lower accessibility in some communities/village in Huangpu, Tianhe and parts of Panyu Districts. The global Moran's <i>I</i> was 0.57 (<i>P</i><0.001), demonstrating significant positive spatial autocorrelation; high-high clusters were observed in Conghua, Zengcheng and Yuexiu Districts, whereas low-low clusters were mainly in the central urban area and western Panyu District except Yuexiu District. Population-based Gini coefficient for ambulance and EMS stations were <0.30, in contrast, the area-based Gini for ambulance was 0.44. Geographically weighted regression results showed that the associations between accessibility and both the number and proportion of residents aged ≥60 years were usually positive, whereas the directions and intensity of the effects of public/medical facility supply variables exhibited spatial heterogeneity. <b>Conclusions:</b> The PEMS generally met response requirements in Guangzhou, however, spatial accessibility showed significant district specific difference and clustering pattern. Travel time was shorter in the central urban district but low-low clustering persist, whereas peripheral district tend to have longer travel times, while parts of Conghua and Zengcheng Districts exhibited relatively higher accessibility. Resource of PEMS allocation was relatively equitable based on population size but imbalanced based on district area. The coverage of PEMS in peripheral districts and the districts with low population density was still limited.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1286-1293"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Effects of exposure to ambient fine particulate matter on dyslipidemia and modifying role of dietary factors in children and adolescents in rural China].","authors":"L J Huang, W Cao, J Xu, H L Wang, H Pan, T T Yang, R H Luo, J F Zhang, H Y Fang, P P Xu, Y H Zheng, Q Zhang, A L Liu","doi":"10.3760/cma.j.cn112338-20251120-00843","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251120-00843","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the association between fine particulate matter (PM_2.5) exposure and dyslipidemia, and the potential modifying role of dietary factors in children and adolescents in rural China. <b>Methods:</b> A multi-stage cluster random sampling method was applied to conduct questionnaire survey, biochemical measurements, and physical examination in children and adolescents aged 8 to 15 years in 103 key surveillance counties where the Nutrition Improvement Program for Rural Compulsory Education Students was conducted. The average PM_2.5 concentration in previous 3 years was used as the long-term exposure level. The linear mixed-effect model was used to evaluate the association between PM_2.5 exposure and dyslipidemia. Stratified analyses by dietary factors were conducted to analyze their potential modifying effects. <b>Results:</b> A total of 10 788 children and adolescents were included, including 5 391 boys (49.97%) and 5 244 primary school students (48.61%). The annual PM_2.5 exposure level was (30.36±10.62) µg/m³, and the prevalence rate of dyslipidemia was 21.84%. Higher PM_2.5 exposure was significantly associated with the increased risk for dyslipidemia (<i>OR</i>=1.501, 95%<i>CI</i>: 1.028-2.192), with stronger associations observed in boys, junior high school students, and those attending schools in county towns. Stratified analyses indicated that no significant association was observed between high PM_2.5 exposure and dyslipidemia in children and adolescents with greater vegetable intake diversity. <b>Conclusions:</b> High level of PM_2.5 exposure increased the risk for dyslipidemia in children and adolescents. Greater diversity of vegetable intake might play a modifying role in the adverse association between PM_2.5 exposure and dyslipidemia.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1258-1263"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Descriptive analysis of characteristics of stepping activity in middle-aged and old adults in 10 areas of China].","authors":"X Y Zhang, Y Z Zhao, Y X Zhao, D J Y Sun, L Pan, P Pei, H D Du, J S Chen, Z M Chen, J Lyu, L M Li, Doherty Aiden, C Q Yu","doi":"10.3760/cma.j.cn112338-20251231-00939","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251231-00939","url":null,"abstract":"<p><p><b>Objective:</b> To investigate the level and intensity of stepping and associated factors in middle-aged and elderly people in the 3^rd resurvey of the China Kadoorie Biobank study project. <b>Methods:</b> The stepping activity level (daily steps, daily stepping duration and stepping intensity (peak 1-minute cadence and peak 30-minute cadence) were obtained by using sports bracelet and calculation. The time, area and population distributions were described by using general linear models. General linear regression model was used to identify associated factors. <b>Results:</b> A total of 20 246 study participants were included in the analysis. The women usually had higher stepping activity level compared with men. The study participants usually had lower stepping activity level on weekdays, but the daily stepping duration was higher. The rural residents had higher stepping level (daily steps: 10 262.1, daily stepping duration:166.0 minutes), whereas the urban residents demonstrated greater stepping intensity (step peaks 109.6 steps within 1 minute and 91.3 steps within 30 minutes). The stepping level showed non-linear relationships with age. Daily steps and daily stepping duration peaked at age 60.7 years and 62.3 years, respectively. The cadence peaks within 1 minute and 30 minutes declined significantly after age 69.2 years. Smoking and suffering from chronic diseases were associated with lower stepping level. <b>Conclusion:</b> The stepping level exhibited significant time, area and population specific characteristics in middle-aged and elderly people in China, which were closely associated with lifestyle and health status.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1199-1207"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Study of associations between childhood phthalate exposure and physical growth].","authors":"J N Jiang, D Gao, J Y Liu, Y Zhang, L Chen, X L Song, R L Wang, Z Y Zou, J Ma, Y H Dong","doi":"10.3760/cma.j.cn112338-20251103-00785","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251103-00785","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the associations between childhood phthalic acid esters (PAEs) exposure and physical growth indicators (body height, body weight, BMI), and their gender specific differences. <b>Methods:</b> Based on data from the three-year follow-up (2018-2020) of Xiamen Puberty Development Cohort, this study included 848 children aged 7-13 years for anthropometric examinations (e.g., body height and body weight) and urinary tests for seven PAEs metabolites. Those who had at least two repeated measurements were included in the analysis. Linear mixed effects model was used to analyze the associations between individual PAEs metabolites and body height Z-score, body weight Z-score, and BMI Z-score. Quantile g-computation was used to analyze the mixture exposure effect, stratified by gender. <b>Results:</b> PAEs metabolites were commonly detected in children's urine. In girls, mono-n-butyl phthalate (MnBP) and mono-2-ethylhexyl phthalate (MEHP) were negatively associated with body height Z-score (MnBP: <i>β</i>=-0.023, 95%<i>CI</i>: -0.041- -0.005; MEHP: <i>β</i>=-0.016, 95%<i>CI</i>: -0.029 - -0.003). In boys, the associations between PAEs metabolites and physical growth indicators had no statistical significance. The mixed exposure to PAEs metabolites showed no statistical significant association with body height Z-score, body weight Z-score, or BMI Z-score. <b>Conclusions:</b> There are gender specific differences in the association between childhood exposure to PAEs and physical growth. Exposure to some PAEs (MnBP, MEHP) is negatively associated with the body height of girls.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1216-1221"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Prevention and control strategies for exported transmission of mosquito-borne infectious diseases based on 2025 Chikungunya fever epidemic prevention and control in Guangzhou].","authors":"J Huang, F X Li, J Z Gan, S J Fan, Y H Liu, R N Zhen, Y L Li, S Y Jiang, Y Q Wu, J Yuan","doi":"10.3760/cma.j.cn112338-20260129-00079","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20260129-00079","url":null,"abstract":"<p><p>The cross-regional transmission of mosquito-borne infectious diseases has become a prominent challenge in current infectious disease prevention and control, posing a severe threat to global public health. Based on prevention and control of the exported transmission of Chikungunya fever epidemic in Guangzhou in 2025, this paper systematically summarizes the definition, identification methods, prevention and control effects or significance of exported cases of mosquito-borne infectious diseases, analyzes their transmission characteristics, introduces the influencing factors, further summarizes the key points for preventing and controlling of the exported transmission and suggests targeted strategies and measures. The results indicated that exported cases of mosquito-borne infectious diseases exhibited a phased characteristic of \"low-level incubation, rapid incidence rise, fluctuating decline\". The exported transmission risk was highly correlated with the incidence level and mosquito density in epidemic focus area. Population mobility is a key factor in the exported transmission of the epidemic, and the transmission process is often unnoticeable. For the prevention and control of exported transmission of mosquito-borne infectious diseases, it is essential to simultaneously implement dual management of infected individuals and mosquito vectors, follow the seasonal activity patterns of mosquitoes, and focus on high-risk areas for mosquito breeding and key populations with cross-regional mobility. Surveillance and early warning, regional coordination and collaboration, management of key places, and populations and public health education are key approaches to managing such diseases exported transmission. The findings can be used as theoretical basis and practical reference for the establishment of a cross-regional prevention and control system for mosquito-borne infectious diseases.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1348-1354"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Medical real-world data governance-Construction of common data model].","authors":"Y Q Zheng, S Y Zhan, F Sun","doi":"10.3760/cma.j.cn112338-20260402-00221","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20260402-00221","url":null,"abstract":"<p><p>Real-world data (RWD) governance is a critical foundation for generating high-quality real-world evidence. However, inconsistencies in data structure, terminology, and quality control across different data sources hinder cross-institutional data integration and use. Against this background, the group standard T/CAS 1170-2025, <i>Medical real-world data governance-Construction of common data model</i>, was developed to provide technical specifications for common data model (CDM) construction for medical RWD. This article interprets the drafting background, main contents, and practical significance of the standard. The standard describes key stages in CDM development, including requirement analysis and data source definition, data model design, terminology standardization and mapping, data integration, model validation and quality assessment, as well as model maintenance and evolution. It also puts forward requirements for data security and compliance, data transparency, bias control, and reproducibility of analytical results. In light of domestic and international practice, CDM has gradually become an important technical foundation for standardized RWD governance, collaborative analysis, and evidence generation. Although China has initiated relevant explorations at the levels of hospitals, specialty platforms, and regional health information systems, these efforts remain relatively fragmented overall. The release of this standard provides a unified framework for medical RWD governance in China, and is expected to improve data standardization, promote multicenter collaboration and data sharing, and support post-marketing evaluation of drugs and the development of regulatory science.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1189-1198"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Health cooperation under the \"Lancang-Mekong Cooperation 2.0\" framework: a decade of retrospection and prospective outlook].","authors":"Z Li, Z C Shao, H Z S Jiang, L Zhang, M H Ren, K Zhai","doi":"10.3760/cma.j.cn112338-20251030-00772","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251030-00772","url":null,"abstract":"<p><p>Since the launch of the Lancang-Mekong Cooperation in 2015, a core platform for regional health governance has been established. This paper systematically deconstructs 28 multilateral official documents issued between 2015 and 2024 by using policy text analysis to trace the logical trajectory of Lancang-Mekong health cooperation's development from project-driven initiatives to institutionalized governance. The study concludes that major public health emergencies within the region is the key factor to improve the institutional development and resource allocation of the system. This has expanded the cooperative agenda from initial joint prevention and control of infectious diseases to a comprehensive governance framework encompassing health service delivery, human resources, information systems, pharmaceutical products, health financing, and leadership and governance. By systematically analyzing achievements in building the six cornerstones of the health system, this paper reveals the platform's systemic integration advantages and collaborative governance effectiveness in addressing complex challenges. Based on the strategic requirement for quality enhancement and upgrading under \"Lancang-Mekong Cooperation 2.0\", this paper suggests continuing the efforts to improve the linkage between \"water and health\", fully implement the \"One Health\" approach, and accelerate digital health transformation to build a more resilient regional health community.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1372-1378"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A study of confounding effect control based on residual strategy with multivariate random forest analysis].","authors":"T X R Deng, M Y Lu, F Shao, D F You, Y Zhao","doi":"10.3760/cma.j.cn112338-20260106-00016","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20260106-00016","url":null,"abstract":"<p><p>By using generalized estimating equation, random intercept model, random coefficients model, and generalized linear model respectively, this study obtained residuals for predictors and outcomes as new predictors and outcomes for multivariate random forest (MRF) analysis. Simulation experiments were conducted to compare the performance of these methods in confounding adjustment under scenarios with varying outcome correlations, causal effect magnitudes, numbers of confounding factors, and sample sizes. United Kingdom Biobank data were used for further validation. Simulation results showed that conventional MRF failed to control type Ⅰ error, whereas the proposed residual-based MRF effectively controlled type Ⅰ error. Notably, the residual strategy based on generalized estimating equation achieved the best performance in identifying important predictors, especially when outcomes were highly correlated. As the number of confounding factors increased, the performance of all the methods declined but remained effective when the causal effect was sufficiently large. With the increase of sample size, the performance of the residual-based MRF became more stable, and the proportion of identifying the true causal predictor as the top variable reached 100%. The United Kingdom Biobank analysis also supported the effectiveness of the residual strategy in adjusting for confounding effect in real-world data.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1333-1340"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A study of parent-of-origin effect of single nucleotide polymorphisms of imprinted gene <i>KCNQ1</i> on risk for hypertension].","authors":"X Y Ye, H Y Zhang, H D Guo, H X Peng, T J Hou, Y X Li, Y X Tan, H Y Gong, W F Wu, Y Zhao, M Y Wang, Y Q Wu, X Y Qin, J Li, D F Chen, Y H Hu, T Wu","doi":"10.3760/cma.j.cn112338-20251113-00824","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251113-00824","url":null,"abstract":"<p><p><b>Objective:</b> To understand the potential parent-of-origin effect (POE) of imprinted gene <i>KCNQ1</i> on the risk for hypertension by using a family-based design. <b>Methods:</b> Probands and their relatives in 9 rural areas in Fangshan District, Beijing, were included in this study. Mixed-effects model was used to evaluate the association between single nucleotide polymorphisms (SNPs) in the <i>KCNQ1</i> gene and hypertension. The POE effects were evaluated by adopting log-linear model, and the interactions between POE and environmental factors, including smoking, alcohol consumption, were analyzed by using <i>Wald χ</i>² test. The POE was assessed by the ratio of maternal relative risk to paternal relative risk (<i>RR_m</i>/<i>RR_f</i>). <b>Results:</b> A total of 195 SNPs in the <i>KCNQ1</i> gene were included in the analysis after quality control. The association analysis in 1 261 study participants identified 13 loci in the <i>KCNQ1</i> gene associated with hypertension (all <i>P</i><0.05). POE analysis, involving 167 study participants from 54 core families, identified 6 loci that showed possible POE with hypertension (all <i>P</i><0.05). The most significant locus was rs231879, with an <i>RR_m</i>/<i>RR_f</i> of 3.46 (95%<i>CI</i>: 1.36-8.57, <i>P</i>=0.009), indicating that the relative risk of inheriting the risk allele from mother was 3.46 times higher than that from father. Analysis on the interactions between POE and environmental exposure revealed that sleep duration might potentially modify the POE of rs170786 (interaction for <i>P</i>=0.023). <b>Conclusion:</b> The imprinted gene <i>KCNQ1</i> might be associated with the risk for hypertension through POE.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1264-1269"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association between exposure to bedroom light-at-night and depressive symptoms in children and adolescents].","authors":"S X Qu, M Liu, J Y Jin, Y Han, F J Ying, F Y Zhang, D L Yang, S L Huang, K Y Zheng, X D Sun, C Y Luo","doi":"10.3760/cma.j.cn112338-20251103-00787","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251103-00787","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the association between the exposure to bedroom light-at-night and depressive symptoms in children and adolescents. <b>Methods:</b> From April to December 2024, a study was conducted in students at grade 4-7 recruited from 3 schools in Shanghai. The 10-item Center for Epidemiological Studies Depression Scale was used to detect depressive symptoms, and a portable illuminance meter was used to measure the intensity of bedroom light-at-night for one week. The log-binomial regression model was applied to analyze the association between the exposure to bedroom light-at-night and depressive symptoms. <b>Results:</b> A total of 628 children and adolescents were included, including 314 boys and 314 girls. The average age of the students was (10.8±1.1) years. The detection rate of depressive symptoms was 26.4%. The median intensity of bedroom light-at-night from 21:00 to 07:00 was 5.1(2.2,10.5) lx, which was higher on schooldays [5.1(1.9,10.1) lx] than that on weekends [4.0(1.3,9.3) lx]. Log-binomial regression analysis showed that during 21:00 - 7:00 , compared with the <i>Q</i>₁ group of exposure to light-at-night, the <i>PR</i> for depressive symptoms in the <i>Q</i>₄ group was 1.431 (95%<i>CI</i>: 1.002-2.043) and during 21:00-22:00, compared with <i>Q</i>₁ group, both the <i>Q</i>₂ and <i>Q</i>₄ groups showed higher <i>PR</i> for depressive symptoms [1.669 (95%<i>CI</i>: 1.136-2.451); 1.538 (95%<i>CI</i>: 1.020-2.319)]. Similar results were observed during 21:00-23:00. During 21:00-24:00, the <i>PR</i> for depressive symptoms in the <i>Q</i>₄ group significantly increased compared with <i>Q</i>₁ group [1.611 (95%<i>CI</i>: 1.064-2.440)]. Associations between different levels of exposure to bedroom light-at-night and depressive symptoms were observed in different times on school days and in girls. No significant association was found between the exposure to bedroom light-at-night and depressive symptoms in boys and on weekends (<i>P></i>0.05). <b>Conclusion:</b> Higher exposure to bedroom light-at-night during 21:00-24:00 was associated with depressive symptoms in children and adolescents, especially in girls and on schooldays.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1243-1249"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}