中华流行病学杂志最新文献

{"title":"[Analysis of the epidemic trend and spatiotemporal clustering of influenza in Shijiazhuang City during the 2023-2026 surveillance years].","authors":"J L Tao, L J Zhang, S Y Zhang, X S Liu, Y R Zhang, H H Liu, H L Ma","doi":"10.3760/cma.j.cn112338-20260415-00256","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20260415-00256","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the epidemic trends and spatiotemporal clustering characteristics of influenza in Shijiazhuang during the 2023-2026 surveillance years, and to provide evidence-based support for the precision prevention and control of influenza. <b>Methods:</b> Data on influenza cases from March 1, 2023 to March 31, 2026 were obtained from the Infectious Disease Reporting Information Management System of Chinese Information System for Disease Control and Prevention. Descriptive epidemiological methods were used to analyze the epidemic characteristics of influenza. Local indicators of spatial association and the SaTScan Poisson-based spatial scan statistic were used for spatial autocorrelation analysis. <b>Results:</b> During the 2023-2026 surveillance years, the annualized incidence rate of influenza in Shijiazhuang was 644.7 per 100 000 person- years, with rates of 370.0 per 100 000 person-years, 616.1 per 100 000 person-years, and 971.9 per 100 000 person-years in 2023, 2024, and 2025 surveillance years, respectively. Students accounted for the largest proportion of cases (30.9%). Three epidemic peaks were identified, occurring in the winters of 2023, 2024, and 2025, and the number of reported cases across these three winter peaks increased year by year. The 2025 influenza season began approximately 2-3 weeks earlier than in the previous two years. Spatial autocorrelation analysis showed a global Moran's <i>I</i> of 0.375 for the surveillance period, with clusters concentrated in the five main urban districts. The global Moran's <i>I</i> values of the second and third epidemic peaks were similar (0.360 and 0.359). Clustering began to stabilize from the second epidemic peak, showing a transmission trend of outward diffusion from the five main urban districts. <b>Conclusions:</b> After the gradual withdrawal of non-pharmaceutical interventions during the 2023-2026 surveillance years, influenza in Shijiazhuang showed a continuously expanding epidemic scale, with the three epidemic peaks increasing in size year by year; students were the most affected population. Spatially, influenza transmission showed a pattern of spreading from the five main urban districts to the near suburbs and spilling over to the outer suburbs, for which the transportation hub effect and regular cross-regional commuting may be the main driving factors. It is recommended to strengthen the promotion of influenza vaccination among school-age children before the start of the autumn semester and to enhance school-based influenza surveillance, and to strengthen influenza surveillance in key venues such as high-speed rail stations and airports and among key populations such as regular commuters.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 8","pages":"1464-1470"},"PeriodicalIF":0.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Associations of serum micronutrients with osteoporotic fracture].","authors":"T Liu, Z H Li, H X Xia, M Y Fan, X Jiang, L Y Fan","doi":"10.3760/cma.j.cn112338-20251124-00847","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251124-00847","url":null,"abstract":"<p><p><b>Objective:</b> To evaluate the relationship between serum micronutrient levels, including calcium, phosphorus, iron, and 25-hydroxyvitamin D, and the incidence of osteoporotic fracture. <b>Methods:</b> A retrospective analysis was performed in 5 984 patients hospitalized in the Department of Osteoporosis, West China Fourth Hospital, Sichuan University, from December 2017 to October 2024. The patients with osteoporotic fracture were divided into case group and those without osteoporotic fracture were divided into control group. Missing data were addressed using multiple imputation. Logistic regression model was used to analyze the association between different micronutrient levels and fracture risk, and mediating effect of bone mineral density was further evaluated. Model discrimination was evaluated using receiver operating characteristic curve and area under the curve (AUC), and differences in AUC were compared by DeLong test. <b>Results:</b> The calcium, phosphorus, and iron levels were significantly lower in patients with osteoporotic fracture than in controls, the difference was significant (all <i>P</i><0.05). After adjustment for age, sex, BMI, and comorbidity, including diabetes, coronary heart disease, and hypertension, the logistic regression analysis showed that calcium level was significantly inversely associated with osteoporotic fractures, and phosphorus, iron, and 25-hydroxyvitamin D were not significantly associated with osteoporotic fractures. After additional mutual adjustment for phosphorus, iron and 25-hydroxyvitamin D, the association between calcium and fracture remained stable (<i>OR</i>=0.88, 95%<i>CI</i>: 0.82-0.94, <i>P</i><0.001). This relationship was consistent in different subgroups, with no significant interactions. Bone mineral density had no effect to mediate the association between micronutrients and fracture. Using calcium level in the baseline model significantly increased the AUC, enhancing its discriminative ability (<i>P</i>=0.002). <b>Conclusions:</b> In patients with osteoporosis, the serum calcium levels showed an inverse association with fracture risk, and maintaining adequate calcium may help reduce this risk. The etiological roles of other serum micronutrients, including phosphorus, iron, and 25-hydroxyvitamin D, remain to be further analyzed.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 8","pages":"1478-1484"},"PeriodicalIF":0.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[An overview of environmental pharmacoepidemiology].","authors":"Z S Fu, Q Chen, Y Deng, S F Wang","doi":"10.3760/cma.j.cn112338-20251108-00805","DOIUrl":"10.3760/cma.j.cn112338-20251108-00805","url":null,"abstract":"<p><p>Environmental pharmacoepidemiology (EPE) is an emerging interdisciplinary field developed to address the health challenges arising from the complex interactions between environmental factors and drug effects. This paper systematically introduces the definitions, core research domains, methodological framework, and public health significance of EPE. The field's primary objective is to integrate data on environmental exposures and drug utilization to evaluate how the environment influences the efficacy and safety of pharmaceuticals, as well as the potential impacts of drugs on the environment. By leveraging exposomics, phenome-wide data, and real-world big data, while applying advanced statistical methods like propensity scores and multilevel models, EPE facilitates a deeper investigation into the intricate \"environment-drug-health\" nexus. While facing challenges such as dynamic exposure assessment, poorly understood interaction mechanisms, and statistical modeling limitations, future advancements in EPE will provide crucial scientific support for achieving precision medicine and advancing the synergistic governance of environmental health.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 8","pages":"1520-1526"},"PeriodicalIF":0.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Bayesian statistics and its applications in medical research].","authors":"Y Zhao, L L Huang, M Y Lu, Z H Zhong, F R Yan, F Chen","doi":"10.3760/cma.j.cn112338-20260123-00064","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20260123-00064","url":null,"abstract":"<p><p>Bayesian statistics dates back to the 18th century. Its development was once hindered by computational complexity. However, as computing methods and technologies have advanced, Bayesian statistics has demonstrated its advantages across many research scenarios, including small-population studies, information borrowing, complex and innovative designs, and dynamic decision-making. Recently, regulatory authorities in China, the United States, and Europe have issued guidelines, acknowledging the role of Bayesian statistics in new drug research and development. This paper introduced the basic concepts, theoretical foundations, and inference frameworks of Bayesian statistics. Bayesian statistics uses Bayes' theorem to combine prior information with sample data to derive the posterior distribution, which serves as the basis for Bayesian inference and decision-making. Unlike the traditional frequentist approach, which focuses on \"analyzing only the data from the current study\", the Bayesian approach aims to \"integrate and use previous information together with current data,\" thereby forming a statistical decision-making approach that continuously accumulates and makes dynamic decision-making. The paper also discussed the strengths and weaknesses of the frequentist and the Bayesian, as well as their respective strengths and weaknesses. The authors note that the two inference frameworks will be used in a complementary manner in the future, and Bayesian methods play an invaluable role in advancing innovative medical research.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 8","pages":"1383-1388"},"PeriodicalIF":0.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Attribution analysis of common respiratory pathogens in influenza-like illness, 2024-2025 surveillance years in Beijing].","authors":"L Zhang, Y Shen, X D Hu, J Li, W Duan, Y Y Wang, J X Ma, J J Zhang, D T Zhang, C N Ma","doi":"10.3760/cma.j.cn112338-20260211-00118","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20260211-00118","url":null,"abstract":"<p><p><b>Objective:</b> Analyze the contribution of common respiratory pathogens to influenza-like illness (ILI) in Beijing during the 2024-2025 surveillance years, and identify the dominant local pathogens and their differences across age groups. <b>Methods:</b> Collect ILI consultation data from secondary-level and above medical institutions in Beijing during the 2024-2025 surveillance year, as well as the positive rates for 22 respiratory pathogens from 19 sentinel hospitals. We used the elastic network model to screen for pathogens, and construct generalized additive models (GAM) for the entire population and each age group separately. Based on the correction of confounding factors such as time and holidays, calculate the attributable contribution of each pathogen to the ILI through the attributable fraction (AF). <b>Results:</b> A total of 1 389 954 cases of ILI were monitored, averaging 26 730 cases per week. A total of 14 pathogens had a positive rate of ≥1.00% among the 22 pathogens. The top 5 pathogens with the highest positive rates were haemophilus influenzae (10.78%,2 188/20 296), streptococcus pneumoniae (10.62%,2 155/20 296), and 2019-nCoV (9.96%,2 021/20 296), influenza virus (9.34%, 1 895/20 296) and rhinovirus (5.79%, 1 175/20 296). In the pathogen attribution analysis, the elastic network model screened out a total of 9 pathogens, with a combined AF of 52.88%, and the number of attributed ILI was 735 008 cases. The top three pathogens by AF (and number of attributed cases) were influenza virus at 20.46% (284 385 cases), rhinovirus at 10.47% (145 528 cases), and human metapneumovirus at 8.09% (112 447 cases). Among the age groups of 0-4 years, 15-59 years and over 60 years, AF of influenza virus was the highest, being 11.71% (95%<i>CI</i>: 0.00%-17.77%), 26.38% (95%<i>CI</i>: 13.60%- 36.94%), and 29.89% (95%<i>CI</i>: 3.30%-37.66%) respectively; among the 5-14 years age group, AF of rhinovirus was the highest, being 9.82% (95%<i>CI</i>: 0.00%-18.37%). <b>Conclusions:</b> During the 2024-2025 surveillance years, the number of patients visiting the outpatient and emergency departments with ILI was caused by multiple pathogens. Influenza virus, rhinovirus, and human metapneumovirus were the main causative pathogens, and their contributions varied across age groups. GAM can effectively measure the disease burden of different pathogens and provide reliable data support for the precise monitoring and stratified prevention and control of respiratory infectious diseases.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 8","pages":"1451-1456"},"PeriodicalIF":0.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Application progress and analysis of public participation in infectious disease surveillance and early warning mechanisms].","authors":"Z P Li, J Y Yao, R Rong, Z H Yu, L Y Yang, S J Shi, H Li","doi":"10.3760/cma.j.cn112338-20251110-00807","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251110-00807","url":null,"abstract":"<p><p>Public participation in the surveillance and early warning of infectious diseases has demonstrated its unique value in implementing the \"Four Early\" principle of prevention and control of infectious diseases, as well as in the research and evaluation of epidemic situations and the formulation of prevention and control strategies. It is an important supplementary measure to enhance surveillance and early warning capacity for infectious diseases and to address the shortcomings of the professional surveillance system. China's current public participation in infectious disease surveillance and early warning is still in its infancy, and there are problems such as insufficient systematization and limited intelligence. This paper analyzes and summarizes the experience and successful cases by systematically sorting out the legal basis, practical experience, and application effect of public participation in infectious disease surveillance and early warning at home and abroad, to provide theoretical support for the construction of China's public participation in the working mechanism and management system of infectious disease surveillance and early warning.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 8","pages":"1533-1538"},"PeriodicalIF":0.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Modification of low-density lipoprotein cholesterol on the relationship of serum testosterone with all-cause mortality in Hainan male centenarians].","authors":"Q Zhu, C Chen, S H Fu, M Liu, Y He, Y L Zhao, X W Cheng, Y Z Chen","doi":"10.3760/cma.j.cn112338-20251119-00838","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251119-00838","url":null,"abstract":"<p><p><b>Objective:</b> To explore the association between serum testosterone and all-cause mortality in Hainan male centenarians, and the modifying effect of low-density lipoprotein cholesterol (LDL-C). <b>Methods:</b> Based on the China Hainan Centenarian Cohort Study, 167 male participants with complete data were followed up for survival status and death outcomes. Restricted cubic splines (RCS), Cox proportional hazards regression model, and Kaplan-Meier survival curves were used to investigate the relationship between testosterone and mortality. The effect of LDL-C on the relationship between testosterone and all-cause mortality was analyzed using the likelihood ratio test. <b>Results:</b> As of March 31, 2023, the median follow-up time <i>M</i>(<i>Q</i>₁, <i>Q</i>₃) was 22.90 (10.00, 48.60) months. RCS results showed a linear negative association between testosterone levels and mortality (<i>P</i>=0.042, <i>P</i> for nonlinear=0.061). Kaplan-Meier survival curves analysis indicated that lower testosterone levels were significantly associated with shorter survival time (22.50 months <i>vs.</i> 28.00 months, <i>P</i>=0.006). Interaction analysis revealed that LDL-C influenced the independent predictive ability of testosterone for all-cause mortality in male centenarians (<i>P</i> for linear <0.001; <i>P</i> for nonlinear=0.003). <b>Conclusions:</b> Among male centenarians in Hainan, decreased serum testosterone levels are associated with an increased risk of all-cause mortality. Furthermore, when serum LDL-C levels are low, the association between testosterone levels and higher mortality is more pronounced.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 8","pages":"1416-1421"},"PeriodicalIF":0.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Associations of body weight perceptions with suicidal ideation and suicidal attempts among middle and high school students in Zhejiang Province].","authors":"Z Yu, Y Y Meng, Y Q Guan, K Huang, W Wu, X F Du, Z M Ma, J M Zhong, M Wang, G P Dong","doi":"10.3760/cma.j.cn112338-20260209-00115","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20260209-00115","url":null,"abstract":"<p><p><b>Objective:</b> To understand the association between body weight perception and suicide related behaviors among middle and high school students in Zhejiang Province, and to provide a basis for body weight management and suicide prevention. <b>Methods:</b> Based on the baseline survey data of the Zhejiang childhood behavior and health cohort, 7 666 subjects were included in this study the use multivariate logistic regression analysis to examine the association between body weight perception and accuracy with suicidal ideation and attempts, and <i>OR</i> with 95%<i>CI</i> were reported. <b>Results:</b> The proportions of feeling moderate, underweight, and overweight were 43.7%, 24.0%, and 32.3%, respectively. The rates of accurate, underestimated, and overestimated weight perception were 61.6%, 22.9%, and 15.5%, respectively. In the past 12 months, 18.4% of students had suicidal ideation, 4.9% had suicidal attempts. After adjustment for potential confounders, analysis results showed that the <i>OR</i>s for suicidal ideation and perceived underweight and overweight were 1.66 (95%<i>CI</i>: 1.40-1.97) and 1.36 (95%<i>CI</i>: 1.14-1.63), respectively; the <i>OR</i>s for suicidal ideation and underestimation and overestimation of body weight were 1.35 (95%<i>CI</i>: 1.15-1.58) and 1.32 (95%<i>CI</i>: 1.09-1.59), respectively. The <i>OR</i>s for suicidal attempts between perceived overweight, and overestimated weight were 1.34 (95%<i>CI</i>: 1.00-1.80) and 1.43 (95%<i>CI</i>: 1.05-1.93), respectively. There is no significant association between BMI and weight perception or weight perception accuracy. <b>Conclusions:</b> BMI is not associated with suicidal behavior. Both perceived overweight and underweight are positively correlated with suicidal ideation in students, while perceived overweight and overweight are positively correlated with suicidal attempts.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 8","pages":"1422-1431"},"PeriodicalIF":0.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148798611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Analysis on critical vaccination challenges in China: a perspective from cross-level theory between individual behavioral cognition and social influence framework].","authors":"H S Liu, M H Guo, F Gao, X F Liang","doi":"10.3760/cma.j.cn112338-20251107-00802","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251107-00802","url":null,"abstract":"<p><p>Vaccination is the cornerstone of global public health by curbing emerging infectious diseases, preventing some cancers, and establishing herd immunity, thereby protecting population health and mitigating disease burden. In recent years, however, challenges, such as stagnated vaccination coverage, increased vaccination hesitancy, and implementation strategies hindered further progress. From a global perspective, this paper summarizes the key factors constraining the sustained development of immunization program in China, analyses these challenges from two dimensions: population behavioral determinants and governmental decision-making mechanisms, discuss the strategic priorities and transformative directions for future immunization program and analyze the key behavioral problems affecting the immunization program in China based on the cross-level theory of individual behavioral cognition and social influence to provide theorical reference and strategic evidence for improvements of the immunization program system, government decision-making, and public confidence, and the development of global immunization barriers.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1355-1362"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Association of urinary molybdenum levels with diabetes in adults aged 18 years and above in China].","authors":"Z Y Hu, Z Li, W Y Shi, L Ding, Y D Wu, Y L Qu, F Zhao, J M Hu, S S Ji, Y W Li, W L Zhang, H C Song, J Y Cai, J F Cai, F Y Long, H L Lai, M K Yu, Y F Ma, Y Zhu, X M Shi, Y B Lyu","doi":"10.3760/cma.j.cn112338-20251119-00837","DOIUrl":"https://doi.org/10.3760/cma.j.cn112338-20251119-00837","url":null,"abstract":"<p><p><b>Objective:</b> To analyze the association of the urinary molybdenum level with diabetes in adults aged ≥18 years in China. <b>Methods:</b> A total of 10 893 adults aged 18-79 years were included from the first round of cross-sectional survey of China National Human Biomonitoring (2017-2018). Fasting venous blood and midcourse random urine samples were collected from them to detect the levels of serum fasting blood glucose and urinary molybdenum. Through physical examination and questionnaire survey, information about their demographic characteristics, dietary frequency, lifestyle and health status were collected. Restricted cubic spline function was used to analyze the dose-response relationship between urinary molybdenum level and the prevalence of diabetes. Multivariate logistic regression model was used to analyze the association between urinary molybdenum level and the prevalence of diabetes. <b>Results:</b> The weighted age of the study participants was (47.42±0.24) years, and 1 125 study participants were diagnosed with diabetes (the weighted prevalence rate: 10.72%). The weighted <i>M</i>(IQR) of urinary molybdenum and creatinine-corrected urinary molybdenum were 51.19 (54.87) μg/L and 48.12 (45.53) μg/g·creatinine, respectively. After adjustment for potential confounders, restricted cubic spline analysis revealed a positive linear dose-response relationship (total <i>P</i>=0.005, <i>P</i> for non-linear=0.055). The odds of diabetes increased by 15% with each 1 natural logarithm unit increase in urinary molybdenumnlevel, according to weighted multivariate logistic regression analysis, the <i>OR</i> was 1.15 (95%<i>CI:</i>1.04-1.28). Subgroup analysis revealed that the association was stronger in men, those living in rural area, and those aged 60-79 years. <b>Conclusion:</b> There is a positive association between the urinary molybdenum level and the prevalence of diabetes in adults in China.</p>","PeriodicalId":23968,"journal":{"name":"中华流行病学杂志","volume":"47 7","pages":"1250-1257"},"PeriodicalIF":0.0,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148593514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}