中华口腔医学杂志最新文献

{"title":"[Effects of microplastics exposure in development of mineralized tissues].","authors":"S H Yu, L W Zheng, M Wan","doi":"10.3760/cma.j.cn112144-20250109-00008","DOIUrl":"10.3760/cma.j.cn112144-20250109-00008","url":null,"abstract":"<p><p>Microplastics are emerging pollutants of increasing concern, which can enter the human body through pathways such as diet, respiration and skin contact, inducing oxidative stress and inflammatory responses and posing a potential risk on the formation and development of mineralized tissues in the body. Early life is a critical period for the formation and development of mineralized tissues. Microplastics can pass though the placental barrier during early life to affect the fetus directly by accumulating in the bone marrow and interfering with the development of the growth plate, leading to abnormal bone growth. Additionally, microplastics can act as carriers to release bisphenol A (BPA), synergistically enhancing the toxicity of pollutants such as lead and zinc oxide, thereby affecting the development of mineralized tissues. Therefore, exposure to microplastics during early life may be a significant environmental factor contributing to the abnormal development of mineralized tissues. Future researches are needed to explore the specific impacts and mechanisms of microplastics on maxillofacial and tooth development, to provide insights and theoretical foundations for the prevention and treatment of diseases related to the development of mineralized tissues.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"928-934"},"PeriodicalIF":0.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Cone beam CT image analysis of mandibular second and third molar association area].","authors":"X Pan, Z T Lin, S F Zhao","doi":"10.3760/cma.j.cn112144-20241217-00493","DOIUrl":"10.3760/cma.j.cn112144-20241217-00493","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To explore the imaging characterization of mandibular third molar (M3) and mandibular second molar (M2) and their associated areas using cone beam CT (CBCT). &lt;b&gt;Methods:&lt;/b&gt; A total of 226 images of patients with concomitant mandibular second and third molars in the Department of Oral and Maxillofacial Medical Imaging of Nanjing Stomatology Hospital were selected to retrospectively analyze their clinical information and imaging manifestations from January 2020 to January 2024, and their clinical information and imaging performances were analyzed. Clinical information included patient's age, gender, and chief complaint; dental tissues (crowns, roots) and periodontal tissues (periodontium, alveolar bone) of the mandibular second molar were evaluated based on their CBCT, and the position (high, medium, low), type of obstruction, dental tissues, periodontal tissues and bone margins of the alveolar bone between them, extent (concave, oblique, flat) and depth of bone defects, and periodontal membrane imaging changes of the mandibular third molars etc. &lt;b&gt;Results:&lt;/b&gt; There were 104 cases of mandibular M2 and M3 as the main complaints and 122 cases of non-main complaints in this study. According to the imaging aspects, the mandibular M2 and M3 associated regions with abnormal CBCT imaging manifestations were mainly categorized into six sagittal representation phenotypes (types Ⅰ-Ⅵ); among them, middle-aged and elderly patients≥45 years of age more often showed abnormal imaging phenotypes (75%), and the peripheral bone defects were more severe. The correlation between the type and height of the mandibular M3 obstruction (high:medium:low=42∶110∶74) and the imaging typology of the mandibular M2 and M3 association regions was statistically significant (&lt;i&gt;P&lt;&lt;/i&gt;0.001). The bone defects between mandibular M2 and M3 of the young patients≤25 years of age were predominantly of the oblique type of resorption (41/69 cases), and the least of the flat type (1/69 cases), whereas flat type could reached 27.8% in the middle-aged and elderly patients≥45 years of age, and the circumferential angle of the peripheral bone defects in the mandibular M2 and M3 regions showed strong correlation with age (&lt;i&gt;P&lt;&lt;/i&gt;0.001), typology (&lt;i&gt;P&lt;&lt;/i&gt;0.001), and the height of the obstruction (&lt;i&gt;P=&lt;/i&gt;0.004). The correlation between defect depth and obstruction height for the same fractal type was statistically significant in the age groups≤25 years and 26-44 years (&lt;i&gt;P&lt;/i&gt;&lt;sub&gt;≤25 years&lt;/sub&gt;=0.0385, &lt;i&gt;P&lt;/i&gt;&lt;sub&gt;26~44 years&lt;/sub&gt;=0.032). There was a significant correlation between mandibular M3 with different types of obstruction, especially proximal-medial (34/43 cases) and horizontal obstruction (8/43 cases), and neighboring M2 suffering from caries (&lt;i&gt;P=&lt;/i&gt;0.004). The correlation between obstruction height (median 46.3%, low 50.0%) and M2 extra-root resorption (80 cases) was statistically significant (&lt;i&gt;P&lt;&lt;/i&gt;0.001). &lt;b&gt;Conclusions:&lt;/b&gt; In this study, we","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"905-914"},"PeriodicalIF":0.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Zheng Linfan's contribution to the strategic thinking of innovative development in oral science].","authors":"B B Li, Y H Shan, Y S Zhou","doi":"10.3760/cma.j.cn112144-20250423-00152","DOIUrl":"10.3760/cma.j.cn112144-20250423-00152","url":null,"abstract":"<p><p>Professor Zheng Linfan has played an important role in pioneering and leading the development of dentistry in China. In the early 1940s, he spearheaded groundbreaking investigations on the oral health status of Chinese students, and guided fundamental researches by clinical issues which led to the establishment of China's first oral histopathology laboratory and the Institute of Stomatology. His remarkable scholarly achievements earned him the National Medical and Health Science Conference Award in 1978. He attached great importance to \"investigation and clinical practice\", \"basic research-driven\", \"interdisciplinary\" and \"international cooperation and exchange\" in the early stage of the development of oral science in China, and therefore formed a four-in-one innovative idea, making important contributions to the innovative research and clinical development of Chinese stomatology. This article bases on professor Zheng Linfan's work and research experience. Through the excavation of archival documents, correspondence, memoirs, historical records, and oral history materials, this article reconstructs his contributions to stomatology in China, and summarizes his academic ideas, practical paths, and ideological values in promoting the construction of the stomatological development system, providing references for enriching the historical narrative of stomatology in China, and assisting contemporary advancements and technological innovation.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 8","pages":"915-920"},"PeriodicalIF":0.0,"publicationDate":"2025-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparison of magnetic resonance images of the temporomandibular joint using different coils].","authors":"X J Zhang, T T Wu, Y Zhang, R Q Guo, Z Yin, Y Zhao, J Wang, T J Li, H M Liu, X C Guo, X H Zhang, W Hou, T T Liu, X F Ma, X H Liu","doi":"10.3760/cma.j.cn112144-20250411-00132","DOIUrl":"10.3760/cma.j.cn112144-20250411-00132","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Objective:&lt;/b&gt; To explore and compare the clinical application value of 8-channel head phased-array coil, an 8-channel temporomandibular joint (TMJ)-specific surface coil, and a single-channel surface coil in TMJ MRI examinations. &lt;b&gt;Methods:&lt;/b&gt; A total of 600 temporomandibular disorders (TMD) patients (1 200 joints) who underwent TMJ MRI examination in the First People's Hospital of Jinzhong from June 2020 to January 2025 were retrospectively screened. Based on inclusion/exclusion criteria, 120 TMD patients (240 joints) with closed-mouth oblique sagittal proton density weighted imaging (OSag PDWI), coronal T2 fat-suppression weighted imaging (OCor fs T2WI) and open-mouth oblique sagittal proton density weighted imaging (OSag PDWI) were included. Patients were divided into groups A, B, and C, with 40 cases in each group. Group A (31female, 9male, median age 24 years old), underwent 8-channel head phased-array coil imaging. Group B (29 female, 11male, median age 23.5 years old) underwent TMJ imaging with an 8-channel surface coil. Group C (29 female, 11male, median age 22.5 years old) underwent single-channel surface coil imaging. There were no significant differences in age, gender, type or disease types among groups (&lt;i&gt;P&gt;&lt;/i&gt;0.05). Six healthy volunteers without TMD (4 female, 2 male, range 19 to 45 years old) underwent imaging with all three coils as self-control. The signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and image quality were compared for five regions of interest (ROI) in both patients and volunteers. &lt;b&gt;Results:&lt;/b&gt; Under the same sequence and the same parameters, SNR and CNR in group B were higher than those in group A, and SNR and CNR in group C were also higher than those in group A, the differences were statistically significant (&lt;i&gt;P&lt;&lt;/i&gt;0.05). However, there were significant differences in SNR and CNR between group B and group C in the closed and open positions of ROI1, the open positions of ROI3 and the open positions of ROI5 (&lt;i&gt;P&lt;&lt;/i&gt;0.05), and there were no significant differences in other positions (&lt;i&gt;P&gt;&lt;/i&gt;0.05). Group B had the best image quality, followed by group C and group A had the worst image quality. There were significant differences in the visualization of OSag PDWI in the closed mouth position, OCor T2WI in the coronal position, and OSag PDWI in the open mouth position, such as condyle, anterior attachment, joint disc, double lamina area, joint cavity and lateral pterygoid muscle (&lt;i&gt;P&lt;&lt;/i&gt;0.05). There were significant differences between group B and group C in showing the joint cavity in the closed mouth position and showing the structure of the bilaminar area in the open mouth position (&lt;i&gt;P&lt;&lt;/i&gt;0.05). There was no significant difference in other regions of interest (&lt;i&gt;P&gt;&lt;/i&gt;0.05). The subjective scores of condyle, anterior attachment, articular disc, bilaminar area, articular cavity, lateral pterygos muscle and other structures were medium to high in group A, high in group B, and hi","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"713-722"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[A bibliometric analysis of research progress in temporomandibular disorders: 2010-2024].","authors":"M Q Liu, Y J Jiang, K K Ma, Y Luo, Z Y Chen","doi":"10.3760/cma.j.cn112144-20250313-00079","DOIUrl":"10.3760/cma.j.cn112144-20250313-00079","url":null,"abstract":"<p><p><b>Objective:</b> To analyze research trends, hotspots, and international collaboration in temporomandibular disorders (TMD) from 2010 to 2024 using bibliometric methods. <b>Methods:</b> A total of 4 368 articles published between January 2010 to December 2024 were retrieved from PubMed using the search strategy temporomandibular disorders[MeSH Terms] OR temporomandibular joint disorders[Title/Abstract]. The R package\"bibliometrix\" was employed to analyze publication statistics, author collaboration networks, and keyword co-occurrence. <b>Results:</b> The annual publication volume in the TMD field increased 3.4-fold from 2010 to 2024, with an average annual output of 291.2 articles. MANFREDINI DANIELE was identified as the most prolific author (74 articles). The <i>Journal of Oral Rehabilitation</i> ranked first in terms of publication quantity (454 articles). The University of São Paulo (Brazil) emerged as the leading contributor, followed by Sichuan University (China) globally. Research hotspots predominantly focused on the DC/TMD diagnostic criteria and pain mechanisms. Analysis of international collaboration networks revealed that core authors (e.g., Lobbezoo F, Manfredini D) have driven advancements in the field through multidisciplinary collaboration (dentistry+psychology+medical imaging). The high-frequency occurrence of the imaging keyword \"magnetic resonance imaging (MRI)\" underscores its pivotal role in diagnosing disc displacement. Chinese institutions (Sichuan University, Peking University) ranked second globally in research output; however, interdisciplinary international collaboration remained limited, with multiple-country publications (MCP) accounting for only 13.0%. <b>Conclusions:</b> TMD research demonstrates interdisciplinary integration, highlighting the need for future emphasis on Asian population studies and innovative diagnostic/therapeutic technologies.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"723-730"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Multidisciplinary treatment of a class Ⅱ division 2 patient with temporomandibular disorders].","authors":"H X Hong, G B Liu, K M Li","doi":"10.3760/cma.j.cn112144-20250206-00037","DOIUrl":"10.3760/cma.j.cn112144-20250206-00037","url":null,"abstract":"","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"775-780"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Multidimensional analysis of cranio-maxillofacial joint-neural interactions and their clinical significance].","authors":"K Jiao","doi":"10.3760/cma.j.cn112144-20250319-00092","DOIUrl":"10.3760/cma.j.cn112144-20250319-00092","url":null,"abstract":"<p><p>The interplay between the skeletal and nervous systems has emerged as a pivotal area in modern medical research. Unlike mesodermal-origin trunk skeletons, craniofacial bones demonstrate distinctive neurobiological properties due to their unique embryonic origin from ectodermal neural crest cells. This article systematically investigates the interaction mechanisms between craniofacial bones and the nervous system across developmental, anatomical, and functional dimensions. It comprehensively elaborates the translational value of this neuro-skeletal association in advancing precision diagnosis and treatment for various pathologies, including temporomandibular joint osteoarthritis, craniofacial bone trauma, and dentition defect restoration. The findings propose novel strategies spanning molecular regulation to clinical translation, offering innovative perspectives for managing craniofacial disorders.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"697-703"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Retrospective analysis of the etiology and treatment of 20 cases of retrograde peri-implantitis].","authors":"M W Li, X M Xu, Y T Zhang, X W Hua, D J Li, X Ding","doi":"10.3760/cma.j.cn112144-20241105-00417","DOIUrl":"10.3760/cma.j.cn112144-20241105-00417","url":null,"abstract":"<p><p><b>Objective:</b> To retrospectively analyze the pathogenic factors of retrograde peri-implantitis (RPI) and assess the effectiveness of treatment, and to provide clinicians evidence for the prevention and treatment of RPI. <b>Methods:</b> A total of 2 731 patients with missing teeth (4 016 implants) who underwent implant restoration in the Department of Stomatology, The First Affiliated Hospital of Wenzhou Medical University between January 2004 and December 2022 were included in the study. According to the diagnostic criteria of RPI, a total of 20 cases (23 implants) of RPI were collected, including 4 female (5 implants) and 16 male (18 implants), and the treatment medical records, intraoral photos and cone beam CT or oral panoramic radiographs records of each patient were collected. Each patient with RPI was treated accordingly and followed up regularly to evaluate its efficacy. <b>Results:</b> After treatment, the follow-up time for 20 patients with clinical symptoms of RPI was 13 (6, 40) months (1 month to 13 years), and the survival rate of the treated implants was 91% (21/23). There were 7 patients (8 implants) with inactive RPI, no clinical symptoms, no loosening of the implant, with normal occlusal load, and the disease was at the inactive stage and was not treated. The pulp vitality of the natural tooth adjacent to the implant was normal, and the implant could function normally. There were 13 patients (15 implants) with infected RPI, 1 patient (1 implant) had no loosening of the implant, and the periapical radiolucency of the implant disappeared after endodontic treatment of the natural tooth adjacent to the implant; 12 patients (14 implants) had clinical symptoms such as implant loosening, pus discharge, etc. Among them, 10 patients (12 implants) were successfully implanted in situ or in adjacent sites after removing the implants, and were successfully implanted after 3 to 20 months. Two patients(2 implants) were removed and no further implants were placed. Among them, 2 implants with infected RPI had cystic lesions, which was similar to natural root apex cysts. <b>Conclusions:</b> The etiology of RPI is related to inflammation of adjacent tooth root tips or bacterial residues from inflammatory lesions in the alveolar bone and bone augmentation. RPI can be treated by perfect root canal treatment of adjacent teeth, removal of inflammatory tissue, or simultaneous guided bone regeneration techniques.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"739-748"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Evolution and innovation of dental handpieces: a historical review and future perspectives].","authors":"Z X Li, K Gao, W Zhang, J Zhou","doi":"10.3760/cma.j.cn112144-20250217-00047","DOIUrl":"10.3760/cma.j.cn112144-20250217-00047","url":null,"abstract":"<p><p>As a core device in dental diagnosis and treatment, dental handpiece and its evolution have played a crucial role in advancing dental medicine. This paper systematically reviews the developmental journey of dental handpiece, from primitive dental drill to modern handpiece, analyzing breakthroughs in rotational speed performance, structural design, and functional expansion, as well as their clinical value. Furthermore, it proposes future clinical needs and innovative directions for dental handpiece development, providing references for innovative research and development of dental handpiece.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"763-768"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Quantitative textual analysis of policies about the national oral health based on the policy tools].","authors":"X N Liu, B Y Pan, C X Wang","doi":"10.3760/cma.j.cn112144-20241213-00477","DOIUrl":"10.3760/cma.j.cn112144-20241213-00477","url":null,"abstract":"<p><p><b>Objective:</b> To explore the characteristics of oral health policies at national government level, thus providing evidence for the ongoing refinement and enhancement of these policies. <b>Methods:</b> This study took the relevant texts reflecting the national government-level oral public health as the research objects, and searched the policy texts on Wanfang Data Knowledge Service Platform and government department websites since 1978. The contents of the policy texts were coded, classified and statistically analyzed. The literature research method, content analysis method and text analysis method were adopted as research tools. From the perspective of policy tools, an analysis framework of X dimension (policy tool dimension) and Y dimension (oral health strategic goal dimension) was constructed to conduct quantitative analysis of the relevant texts of oral public health. <b>Results:</b> A total of 195 policy texts were included in the analysis. From the perspective of the document type, published time and issuing department, notification documents [89.74% (175/195)], documents published at the fourth stage [47.69% (93/195)], documents published by National Health Commission of the People's Republic of China [72.31% (141/195)] accounted for the highest proportion. From the perspective of the X and Y dimension, environment-based policy tools [71.18% (247/347)], as well as oral health promotion and oral disease prevention [40.47% (155/383)] accounted for the highest proportion respectively. <b>Conclusions:</b> Since 1978, the number of oral public health policies issued in China has shown an upward trend, reflecting the strengthening of the coordinated role of various departments, the inclusion of oral health work in the important policies of government health and hygiene, and taking into account the Chinese characteristics of local areas. With the strategic goals of WHO as a reference, it shows that China's policies in terms of health workforce, oral health information system and oral health research agenda are relatively insufficient. The structure of X and Y policy tools in China is unbalanced and needs to be improved.</p>","PeriodicalId":23965,"journal":{"name":"中华口腔医学杂志","volume":"60 7","pages":"749-756"},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}